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M.", "lastName": "Wolff" } ], "abstractNote": "", "publicationTitle": "Medicine", "publisher": "", "place": "United States", "date": "1973 Nov", "volume": "52", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "535-561", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Medicine (Baltimore)", "DOI": "10.1097/00005792-197311000-00002", "citationKey": "", "url": "", "accessDate": "", "PMID": "4748591", "PMCID": "", "ISSN": "0025-7974", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Azathioprine/therapeutic use" }, { "tag": "Biopsy" }, { "tag": "Corneal Ulcer/etiology" }, { "tag": "Cyclophosphamide/therapeutic use" }, { "tag": "Diagnosis, Differential" }, { "tag": "Ear Diseases/etiology" }, { "tag": "Eye Manifestations" }, { "tag": "Female" }, { "tag": "Granulomatosis with Polyangiitis/complications/*diagnosis/drug therapy" }, { "tag": "Humans" }, { "tag": "Kidney Diseases/drug therapy/etiology/pathology" }, { "tag": "Lung Diseases/diagnostic imaging/etiology" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Nasal Septum/pathology" }, { "tag": "Neurologic Manifestations" }, { "tag": "Paranasal Sinuses/diagnostic imaging" }, { "tag": "Radiography" }, { "tag": "Sinusitis/etiology" }, { "tag": "Skin Manifestations" }, { "tag": "Vascular Diseases/diagnosis" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "M8NQB8PA", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/M8NQB8PA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/M8NQB8PA", "type": "text/html" } }, "meta": { "creatorSummary": "Horn et al.", "parsedDate": "1974-03", "numChildren": 0 }, "data": { "key": "M8NQB8PA", "version": 158766, "itemType": "journalArticle", "title": "Renal biopsy pathology in Wegener's granulomatosis.", "creators": [ { "creatorType": "author", "firstName": "R. G.", "lastName": "Horn" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Rosenthal" }, { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" } ], "abstractNote": "Eighteen renal biopsies from 10 patients with active generalized Wegener's granulomatosis (GWG), with GWG in remission on therapy, and with active localized Wegener's granulomatosis (LWG) have been examined by light and electron microscopy. In all 9 patients with active GWG, light microscopy revealed focal and segmental glomerulonephritis. Electron microscopy revealed subepithelial basement membrane densities resembling immune complex deposits in two biopsies from patients with active GWG. In biopsies from patients on cytotoxic therapy, there was no active inflammatory process, but focal glomercular obsolescence and segmental tuft sclerosis provided evidence of prior focal and segmental glomercular disease. Discrete zones of basement membrane crimping and increased mesangial material along the capillary wall were observed in some patients with apparent LWG, as well as proven GWG, possibly representing foci of previous glomerular injury. The appearance of dense deposits on the epithelial side of the basement membrane suggests that immune complex deposition in the glomeruli may be at least partially responsible for the renal injury in Wegener's granulomatosis.", "publicationTitle": "The American journal of pathology", "publisher": "", "place": "United States", "date": "1974 Mar", "volume": "74", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "423-440", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Am J Pathol", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "4592552", "PMCID": "PMC1910796", "ISSN": "0002-9440 1525-2191", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Antigen-Antibody Complex" }, { "tag": "Azathioprine/therapeutic use" }, { "tag": "Biopsy" }, { "tag": "Blood Urea Nitrogen" }, { "tag": "Cyclophosphamide/therapeutic use" }, { "tag": "Granulomatosis with Polyangiitis/drug therapy/immunology/*pathology/physiopathology" }, { "tag": "Humans" }, { "tag": "Kidney Function Tests" }, { "tag": "Kidney Glomerulus/immunology/pathology" }, { "tag": "Kidney/immunology/*pathology/physiopathology" }, { "tag": "Microscopy, Electron" }, { "tag": "Microscopy, Phase-Contrast" }, { "tag": "Prednisone/therapeutic use" }, { "tag": "Triamcinolone/therapeutic use" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "4427UJQ6", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/4427UJQ6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/4427UJQ6", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci et al.", "parsedDate": "1974-08", "numChildren": 0 }, "data": { "key": "4427UJQ6", "version": 158766, "itemType": "journalArticle", "title": "Cyclophosphamide and lymphocyte subpopulations in Wegener's granulomatosis.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" }, { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" } ], "abstractNote": "", "publicationTitle": "Arthritis and rheumatism", "publisher": "", "place": "United States", "date": "1974 Jul-Aug", "volume": "17", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "355-361", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Arthritis Rheum", "DOI": "10.1002/art.1780170404", "citationKey": "", "url": "", "accessDate": "", "PMID": "4604290", "PMCID": "", "ISSN": "0004-3591", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Antigens" }, { "tag": "Cyclophosphamide/administration & dosage/pharmacology/*therapeutic use" }, { "tag": "Dose-Response Relationship, Drug" }, { "tag": "Female" }, { "tag": "Granulomatosis with Polyangiitis/*drug therapy/immunology" }, { "tag": "Humans" }, { "tag": "Immune Adherence Reaction" }, { "tag": "In Vitro Techniques" }, { "tag": "Leukocyte Count" }, { "tag": "Lymphocytes/*drug effects/immunology" }, { "tag": "Male" }, { "tag": "Microscopy, Phase-Contrast" }, { "tag": "Middle Aged" }, { "tag": "Mitogens" }, { "tag": "Sheep/immunology" }, { "tag": "T-Lymphocytes/drug effects/immunology" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "JCWJPUAY", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/JCWJPUAY", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/JCWJPUAY", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci and Dale", "parsedDate": "1974-01", "numChildren": 0 }, "data": { "key": "JCWJPUAY", "version": 158766, "itemType": "journalArticle", "title": "The effect of in vivo hydrocortisone on subpopulations of human lymphocytes.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" } ], "abstractNote": "This study was designed to determine the effect of in vivo hydrocortisone on subpopulations of lymphoid cells in normal humans. Subjects received a single intravenous dose of either 100 mg or 400 mg of hydrocortisone, and blood was drawn at hourly intervals for 6 h, and then again at 10 and 24 h after injection. Profound decreases in absolute numbers of circulating lymphocytes and monocytes occurred at 4-6 h after both 100 mg and 400 mg of hydrocortisone. Counts returned to normal by 24 h. The relative proportion of circulating thymus-derived lymphocytes as measured by the sheep red blood cell rosette assay decreased maximally by 4 h and returned to base line 24 h after hydrocortisone. There was a selective depletion of functional subpopulations of lymphocytes as represented by differential effects on in vitro stimulation with various mitogens and antigens. Phytohaemagglutinin response was relatively unaffected, while responses to concanavalin A were significantly diminished. Responses to pokeweed mitogen were unaffected by 100 mg of hydrocortisone, but greatly diminished by 400 mg of hydrocortisone. In vitro responses to the antigens streptokinase-streptodornase and tetanus toxoid were markedly diminished by in vivo hydrocortisone. Reconstitution of monocyte-depleted cultures with autologous monocytes partially corrected the diminished response to antigens. This transient selective depletion of monocytes and subsets of human lymphocytes by a single dose of hydrocortisone is most compatible with a redistribution of these cells out of the circulation into other body compartments.", "publicationTitle": "The Journal of clinical investigation", "publisher": "", "place": "United States", "date": "1974 Jan", "volume": "53", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "240-246", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Clin Invest", "DOI": "10.1172/JCI107544", "citationKey": "", "url": "", "accessDate": "", "PMID": "4808638", "PMCID": "PMC301459", "ISSN": "0021-9738", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Blood Cell Count" }, { "tag": "Concanavalin A/antagonists & inhibitors/pharmacology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Hydrocortisone/administration & dosage/*pharmacology" }, { "tag": "Immune Adherence Reaction" }, { "tag": "Lectins/antagonists & inhibitors/pharmacology" }, { "tag": "Lymphocytes/*drug effects" }, { "tag": "Male" }, { "tag": "Mitogens/antagonists & inhibitors/pharmacology" }, { "tag": "Monocytes/drug effects" }, { "tag": "Streptodornase and Streptokinase/antagonists & inhibitors/pharmacology" }, { "tag": "Tetanus Toxoid/antagonists & inhibitors/pharmacology" }, { "tag": "Time Factors" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "47EYX5AW", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/47EYX5AW", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/47EYX5AW", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci and Wolff", "parsedDate": "1974-04", "numChildren": 0 }, "data": { "key": "47EYX5AW", "version": 158766, "itemType": "journalArticle", "title": "Letter: Immunological features of Wegener's granulomatosis.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" } ], "abstractNote": "", "publicationTitle": "Lancet (London, England)", "publisher": "", "place": "England", "date": "1974 Apr", "volume": "1", "issue": "7859", "section": "", "partNumber": "", "partTitle": "", "pages": "688-689", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Lancet", "DOI": "10.1016/s0140-6736(74)93250-4", "citationKey": "", "url": "", "accessDate": "", "PMID": "4132363", "PMCID": "", "ISSN": "0140-6736", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Complement System Proteins/isolation & purification" }, { "tag": "Cyclophosphamide/therapeutic use" }, { "tag": "Fluorescent Antibody Technique" }, { "tag": "Granulomatosis with Polyangiitis/drug therapy/etiology/*immunology" }, { "tag": "Humans" }, { "tag": "Hypersensitivity, Delayed" }, { "tag": "Immune Complex Diseases/complications" }, { "tag": "Immunoglobulins/isolation & purification" }, { "tag": "Kidney/immunology" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "U9TTL5G3", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/U9TTL5G3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/U9TTL5G3", "type": "text/html" } }, "meta": { "creatorSummary": "Wolff et al.", "parsedDate": "1974-10", "numChildren": 0 }, "data": { "key": "U9TTL5G3", "version": 158766, "itemType": "journalArticle", "title": "Wegener's granulomatosis.", "creators": [ { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "R. G.", "lastName": "Horn" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" } ], "abstractNote": "", "publicationTitle": "Annals of internal medicine", "publisher": "", "place": "United States", "date": "1974 Oct", "volume": "81", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "513-525", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Ann Intern Med", "DOI": "10.7326/0003-4819-81-4-513", "citationKey": "", "url": "", "accessDate": "", "PMID": "4416890", "PMCID": "", "ISSN": "0003-4819", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Granulomatosis with Polyangiitis/diagnosis" }, { "tag": "Adolescent" }, { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Azathioprine/administration & dosage/therapeutic use" }, { "tag": "Child" }, { "tag": "Child, Preschool" }, { "tag": "Cyclophosphamide/administration & dosage/immunology/pharmacology/therapeutic use" }, { "tag": "Diagnosis, Differential" }, { "tag": "Ear Diseases/etiology" }, { "tag": "Eye Diseases/etiology" }, { "tag": "Female" }, { "tag": "Follow-Up Studies" }, { "tag": "Heart Diseases/etiology" }, { "tag": "Hematologic Diseases/etiology" }, { "tag": "Humans" }, { "tag": "Immunosuppression Therapy" }, { "tag": "Infant" }, { "tag": "Kidney Diseases/etiology/pathology" }, { "tag": "Kidney Glomerulus/pathology" }, { "tag": "Leukocyte Count" }, { "tag": "Leukocytes/drug effects" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "National Institutes of Health (U.S.)" }, { "tag": "Nervous System Diseases/etiology" }, { "tag": "Respiratory Tract Diseases/etiology/pathology" }, { "tag": "Skin Diseases/etiology" }, { "tag": "United States" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "5X94JY8P", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/5X94JY8P", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/5X94JY8P", "type": "text/html" } }, "meta": { "creatorSummary": "Dale et al.", "parsedDate": "1974-11-28", "numChildren": 0 }, "data": { "key": "5X94JY8P", "version": 158766, "itemType": "journalArticle", "title": "Alternate-day prednisone. Leukocyte kinetics and susceptibility to infections.", "creators": [ { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" } ], "abstractNote": "", "publicationTitle": "The New England journal of medicine", "publisher": "", "place": "United States", "date": "1974 Nov 28", "volume": "291", "issue": "22", "section": "", "partNumber": "", "partTitle": "", "pages": "1154-1158", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "N Engl J Med", "DOI": "10.1056/NEJM197411282912203", "citationKey": "", "url": "", "accessDate": "", "PMID": "4609038", "PMCID": "", "ISSN": "0028-4793", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adolescent" }, { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Child" }, { "tag": "Female" }, { "tag": "Half-Life" }, { "tag": "Humans" }, { "tag": "Infections/*etiology/immunology" }, { "tag": "Inflammation/drug therapy" }, { "tag": "Isoflurophate" }, { "tag": "Kinetics" }, { "tag": "Leukocyte Count" }, { "tag": "Leukocytes/*drug effects/immunology" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Monocytes/drug effects/metabolism" }, { "tag": "Neutrophils/drug effects/metabolism" }, { "tag": "Phosphorus Radioisotopes" }, { "tag": "Prednisone/*administration & dosage/adverse effects/therapeutic use" }, { "tag": "Skin Window Technique" }, { "tag": "Time Factors" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "7MYYBK6X", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/7MYYBK6X", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/7MYYBK6X", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci and Dale", "parsedDate": "1975-01", "numChildren": 0 }, "data": { "key": "7MYYBK6X", "version": 158766, "itemType": "journalArticle", "title": "Alternate-day prednisone therapy and human lymphocyte subpopulations.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" } ], "abstractNote": "The mechanisms and kinetics of the immunosuppressive effects of alternate-day prednisone were investigated in a group of patients with a variety of inflammatory diseases receiving a range of alternate-day prednisone doses from 5 to 120 mg. Total circulating lymphocyte and monocyte counts, as well as proportions of lymphocyte subpopulations defined both by surface markers and by in vitro functional capacities, were studied. At 8 a. m. of the day on prednisone, just before drug administration, lymphocyte and monocyte counts, proportions of lymphocyte subpopulations, as well as in vitro lymphocyte blastogenic responses to various mitogenic and antigenic stimuli were normal. 4 h after the administration of prednisone, there was a profound lymphocytopenia and monocytopenia, with a differential depletion of thymus-derived lymphocytes as well as various functionally defined lymphocyte subpopulations. Lymphocyte kinetic studies using a radioactive chromium-labeled autologous lymphocytes showed that the lymphocytopenia was due predominantly to a transient depletion of the recirculating portion of the intravascular lymphocytepool. All these parameters returned to normal by 8 a.m. of the following day (off prednisone) and remained normal throughout the day. This very transient lymphocytopenia and monocytopenia after prednisone, with normal cell numbers, proportions, and functions throughout the remainder of the 2-day cycle, was associated with suppression of disease activity, yet did not affect cutaneous delayed hypersensitivity in these patients nor increase the likelihood of infectious complications. This drug-associated cyclic and transient monocytopenia and selective lymphocytopenia is best explained by a redistribution of recirculating lymphocytes to other body compartments, particularly the bone marrow.", "publicationTitle": "The Journal of clinical investigation", "publisher": "", "place": "United States", "date": "1975 Jan", "volume": "55", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "22-32", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Clin Invest", "DOI": "10.1172/JCI107914", "citationKey": "", "url": "", "accessDate": "", "PMID": "1078546", "PMCID": "PMC301713", "ISSN": "0021-9738", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adolescent" }, { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Chromium Radioisotopes" }, { "tag": "Collagen Diseases/blood/*drug therapy" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Hypersensitivity, Delayed/immunology" }, { "tag": "Immunosuppression Therapy" }, { "tag": "Inflammation/blood/*drug therapy" }, { "tag": "Intradermal Tests" }, { "tag": "Kinetics" }, { "tag": "Leukocyte Count" }, { "tag": "Lymphocyte Activation/drug effects" }, { "tag": "Lymphocyte Depletion" }, { "tag": "Lymphocytes/*drug effects/immunology" }, { "tag": "Lymphopenia/chemically induced" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Monocytes/drug effects/immunology" }, { "tag": "Prednisone/*administration & dosage/pharmacology/therapeutic use" }, { "tag": "Skin/immunology" }, { "tag": "T-Lymphocytes/drug effects/immunology" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "EPUSGN3W", "version": 158766, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/EPUSGN3W", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/EPUSGN3W", "type": "text/html" } }, "meta": { "creatorSummary": "Wolff et al.", "parsedDate": "1975", "numChildren": 0 }, "data": { "key": "EPUSGN3W", "version": 158766, "itemType": "journalArticle", "title": "Unusual etiologies of fever and their evaluation.", "creators": [ { "creatorType": "author", "firstName": "S. M.", "lastName": "Wolff" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" } ], "abstractNote": "", "publicationTitle": "Annual review of medicine", "publisher": "", "place": "United States", "date": "1975", "volume": "26", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "277-281", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Annu Rev Med", "DOI": "10.1146/annurev.me.26.020175.001425", "citationKey": "", "url": "", "accessDate": "", "PMID": "1096764", "PMCID": "", "ISSN": "0066-4219", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Bacterial Infections/complications" }, { "tag": "Body Temperature Regulation" }, { "tag": "Circadian Rhythm" }, { "tag": "Communicable Diseases/complications" }, { "tag": "Diagnosis, Differential" }, { "tag": "Fever of Unknown Origin/*etiology" }, { "tag": "Granulomatous Disease, Chronic/complications" }, { "tag": "Humans" }, { "tag": "Medical History Taking" }, { "tag": "Metabolic Diseases/complications" }, { "tag": "Neoplasms/complications" }, { "tag": "Recurrence" }, { "tag": "Rheumatic Fever/complications" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "HKLVB5I5", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/HKLVB5I5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/HKLVB5I5", "type": "text/html" } }, "meta": { "creatorSummary": "Balow et al.", "parsedDate": "1975-03", "numChildren": 0 }, "data": { "key": "HKLVB5I5", "version": 158765, "itemType": "journalArticle", "title": "Immunosuppressive effects of glucocorticosteroids: differential effects of acute vs chronic administration on cell-mediated immunity.", "creators": [ { "creatorType": "author", "firstName": "J. E.", "lastName": "Balow" }, { "creatorType": "author", "firstName": "D. L.", "lastName": "Hurley" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "The effects of acute vs. chronic glucocorticosteroid administration on established cellular immune responses were studied in guinea pigs previously sensitized to tuberculin. A greater than 50% reduction in circulating lymphocytes was observed 4 hr after injection of soluble hydrocortisone and 24 hr after daily subcutaneous injections of depot cortisone acetate. After a single dose of hydrocortisone, peripheral lymphocyte migration inhibitory factor (MIF) production and antigen and mitogen-induced proliferation were unchanged. However, the peripheral lymphocytes remaining in the circulation after chronic cortisone treatment showed a marked decrease in both antigen-induced MIF and proliferation, although mitogen responses remained normal. Although similar levels of lymphocytopenia were induced by acute and chronic glucocorticosteroid administration, only chronic treatment was associated with depression of certain cell-mediated lymphocyte functions. The available evidence suggests that these changes may depend on GCS-induced selective alterations in the circulation patterns of certain subpopulations of lymphocytes.", "publicationTitle": "Journal of immunology (Baltimore, Md. : 1950)", "publisher": "", "place": "England", "date": "1975 Mar", "volume": "114", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "1072-1076", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Immunol", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "803535", "PMCID": "", "ISSN": "0022-1767", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Immunity, Cellular" }, { "tag": "Animals" }, { "tag": "Cell Migration Inhibition" }, { "tag": "Concanavalin A" }, { "tag": "Cortisone/pharmacology" }, { "tag": "Freund's Adjuvant" }, { "tag": "Glucocorticoids/*administration & dosage" }, { "tag": "Guinea Pigs" }, { "tag": "Hydrocortisone/blood/pharmacology" }, { "tag": "Injections, Intravenous" }, { "tag": "Injections, Subcutaneous" }, { "tag": "Lectins" }, { "tag": "Lymphocyte Activation/drug effects" }, { "tag": "Lymphocyte Depletion" }, { "tag": "Lymphocytes/immunology" }, { "tag": "Macrophage Migration-Inhibitory Factors/biosynthesis" }, { "tag": "Methylprednisolone/pharmacology" }, { "tag": "Mitogens" }, { "tag": "Mycobacterium tuberculosis/immunology" }, { "tag": "Tuberculin" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "WGFAEQRV", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/WGFAEQRV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/WGFAEQRV", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci", "parsedDate": "1975-03", "numChildren": 0 }, "data": { "key": "WGFAEQRV", "version": 158765, "itemType": "journalArticle", "title": "Corticosteroids and circulating lymphocytes.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "", "publicationTitle": "Transplantation proceedings", "publisher": "", "place": "United States", "date": "1975 Mar", "volume": "7", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "37-40", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Transplant Proc", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "804193", "PMCID": "", "ISSN": "0041-1345", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Administration, Oral" }, { "tag": "Animals" }, { "tag": "Cell Movement" }, { "tag": "Chromium Radioisotopes" }, { "tag": "Glucocorticoids/*pharmacology" }, { "tag": "Guinea Pigs" }, { "tag": "Haplorhini" }, { "tag": "Humans" }, { "tag": "Hydrocortisone/pharmacology" }, { "tag": "Lymph Nodes/drug effects" }, { "tag": "Lymphocyte Depletion" }, { "tag": "Lymphocytes/*drug effects" }, { "tag": "Lymphopenia/chemically induced" }, { "tag": "Methylprednisolone/pharmacology" }, { "tag": "Mice" }, { "tag": "Organ Size/drug effects" }, { "tag": "Prednisolone/pharmacology" }, { "tag": "Prednisone/pharmacology" }, { "tag": "Rabbits" }, { "tag": "Rats" }, { "tag": "Species Specificity" }, { "tag": "Spleen/drug effects" }, { "tag": "T-Lymphocytes" }, { "tag": "Thymus Gland/drug effects" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "V32ULLM6", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/V32ULLM6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/V32ULLM6", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci", "parsedDate": "1975-04", "numChildren": 0 }, "data": { "key": "V32ULLM6", "version": 158765, "itemType": "journalArticle", "title": "Mechanisms of corticosteroid action on lymphocyte subpopulations. I. Redistribution of circulating T and b lymphocytes to the bone marrow.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "The effect of corticosteroid administration on the redistribution of sirculating lymphocytes was studied in the guinea-pig, since this species closely resembles man in its relative resistance to the lymphopenic effect of corticosteroids. A single intravenous injection of hydrocortisone (either 10 mg or 100 mg/kg) caused a profound but transient lymphocytopenia which was maximal at 4 hours following injection, with a returnto normal counts by 24 hours. There was a proportionately greater decrease in circulating T lymphocytes compared to B lymphocytes, although both populations were diminished. Chronic cortisone acetate treatment (100 mg/kg subcutaneously for 7 days) caused a similiar pattern of lymphocytopenia except that it was sustained during the period of chronically elevated plasma cortisol levels. The lymphocytes remaining inthe circulation during the period of lymphocytopenia responded normally in vitro to the mitogens phytohemagglutinin, concanavalin A, and pokeweek mitogen. There was very littleeffect of corticosteroid administration on the numbers, proportions, or mitogenic response of splenic lymphocytes. There was a dramatic increase in the bone marrow of proportions and absolute numbers of lymphocytes bearing surface T-and B-cell markers, as well as a marked increase in response of bone marrow lymphocytes to mitogenic stimulation during the period of maximal circulating lymphocytopenia caused by the administration of corticosteroids, especially chronic cortisone acetate. There was a preferential homing of reinfused -51Cr-labelled syngeneic peripheral blood lymphocytes to the bone marrow of corticosteroid-treated recipients. These studies demonstrate aredistribution of circulating lymphocytes to the bone marrow during corticosteroid treatment, resulting in an increase in immunocompetence of this compartment, while the peripheral blood lymphocyte compartment is quantitatively immunosuppressed due to a lymphocytopenia.", "publicationTitle": "Immunology", "publisher": "", "place": "England", "date": "1975 Apr", "volume": "28", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "669-680", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Immunology", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "1080130", "PMCID": "PMC1445841", "ISSN": "0019-2805 1365-2567", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Animals" }, { "tag": "B-Lymphocytes/*drug effects" }, { "tag": "Bone Marrow/drug effects/*immunology" }, { "tag": "Chromium Radioisotopes" }, { "tag": "Concanavalin A/pharmacology" }, { "tag": "Cortisone/pharmacology" }, { "tag": "Erythrocytes/immunology" }, { "tag": "Female" }, { "tag": "Guinea Pigs" }, { "tag": "Hydrocortisone/blood/*pharmacology" }, { "tag": "Immune Adherence Reaction" }, { "tag": "Immunosuppression Therapy" }, { "tag": "Lectins/pharmacology" }, { "tag": "Leukocyte Count" }, { "tag": "Lymphopenia/chemically induced" }, { "tag": "Rabbits" }, { "tag": "Sheep/immunology" }, { "tag": "T-Lymphocytes/*drug effects" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "7XW8YFB6", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/7XW8YFB6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/7XW8YFB6", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci and Dale", "parsedDate": "1975-04-24", "numChildren": 0 }, "data": { "key": "7XW8YFB6", "version": 158765, "itemType": "journalArticle", "title": "Letter: Monocytopenia after prednisone.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Dale" } ], "abstractNote": "", "publicationTitle": "The New England journal of medicine", "publisher": "", "place": "United States", "date": "1975 Apr 24", "volume": "292", "issue": "17", "section": "", "partNumber": "", "partTitle": "", "pages": "928", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "N Engl J Med", "DOI": "10.1056/NEJM197504242921722", "citationKey": "", "url": "", "accessDate": "", "PMID": "1117923", "PMCID": "", "ISSN": "0028-4793", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Humans" }, { "tag": "Leukocyte Count" }, { "tag": "Leukopenia/*chemically induced" }, { "tag": "Monocytes/*drug effects" }, { "tag": "Prednisone/*adverse effects" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "EPBXICXF", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/EPBXICXF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/EPBXICXF", "type": "text/html" } }, "meta": { "creatorSummary": "Hurley and Fauci", "parsedDate": "1975-05", "numChildren": 0 }, "data": { "key": "EPBXICXF", "version": 158765, "itemType": "journalArticle", "title": "Disseminated candidiasis. i. an experimental model in the guinea pig.", "creators": [ { "creatorType": "author", "firstName": "D. L.", "lastName": "Hurley" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "A model of experimental disseminated candidiasis was developed in the guinea pig; Candida albicans was injected intraperitoneally or intravenously. The kidney was the most severely affected organ, with maximal colony counts of 26,208 plus or minus 9,152 colony-forming units/g of tissue five days after a sublethal inocluation (one-sixth of the 50% lethal dose) of viable organisms. The heart was the next most severely affected organ, and other organs were affected little. Histologic studies confirmed the data from colony counts and showed a progression of inflammation similar to that seen in human disease. A leukocytosis predominantly of mononuclear cells, and to a lesser degree of granulocytes, occurred and was maximal four days after inoculation. This model will provide the framework for a series of future studies of the various factors important in natural host defense against infection with Candida, as well as the effects of various immunosuppressive agents, particularly corticosteroids, on the development and expression of immunity and protection against infection.", "publicationTitle": "The Journal of infectious diseases", "publisher": "", "place": "United States", "date": "1975 May", "volume": "131", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "516-527", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Infect Dis", "DOI": "10.1093/infdis/131.5.516", "citationKey": "", "url": "", "accessDate": "", "PMID": "1092767", "PMCID": "", "ISSN": "0022-1899", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Disease Models, Animal" }, { "tag": "Adrenal Glands/pathology" }, { "tag": "Animals" }, { "tag": "Candida albicans/*immunology" }, { "tag": "Candidiasis/*immunology" }, { "tag": "Female" }, { "tag": "Guinea Pigs" }, { "tag": "Heart/microbiology" }, { "tag": "Kidney/microbiology/pathology" }, { "tag": "Leukocyte Count" }, { "tag": "Leukocytosis/etiology" }, { "tag": "Liver/pathology" }, { "tag": "Male" }, { "tag": "Myocardium/pathology" }, { "tag": "Spleen/pathology" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "CBRFPRNT", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/CBRFPRNT", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/CBRFPRNT", "type": "text/html" } }, "meta": { "creatorSummary": "Chusid et al.", "parsedDate": "1975-05", "numChildren": 0 }, "data": { "key": "CBRFPRNT", "version": 158765, "itemType": "journalArticle", "title": "Letter: Pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease.", "creators": [ { "creatorType": "author", "firstName": "M. J.", "lastName": "Chusid" }, { "creatorType": "author", "firstName": "J. A.", "lastName": "Gelfand" }, { "creatorType": "author", "firstName": "C.", "lastName": "Nutter" }, { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "", "publicationTitle": "Annals of internal medicine", "publisher": "", "place": "United States", "date": "1975 May", "volume": "82", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "682-683", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Ann Intern Med", "DOI": "10.7326/0003-4819-82-5-682", "citationKey": "", "url": "", "accessDate": "", "PMID": "1094876", "PMCID": "", "ISSN": "0003-4819", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Aspergillus fumigatus/isolation & purification" }, { "tag": "*Cannabis" }, { "tag": "*Smoke" }, { "tag": "Adolescent" }, { "tag": "Aspergillosis/*etiology" }, { "tag": "Granulomatous Disease, Chronic/*immunology" }, { "tag": "Humans" }, { "tag": "Lung Diseases, Fungal/*etiology" }, { "tag": "Male" }, { "tag": "Phagocyte Bactericidal Dysfunction/*immunology" }, { "tag": "Phagocytosis" }, { "tag": "Soil Microbiology" }, { "tag": "Substance-Related Disorders/*complications" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } }, { "key": "F96TI5IH", "version": 158765, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/F96TI5IH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/F96TI5IH", "type": "text/html" } }, "meta": { "creatorSummary": "Fauci", "parsedDate": "1975-07", "numChildren": 0 }, "data": { "key": "F96TI5IH", "version": 158765, "itemType": "journalArticle", "title": "Human bone marrow lymphocytes. I. Distribution of lymphocyte subpopulations in the bone marrow of normal individuals.", "creators": [ { "creatorType": "author", "firstName": "A. S.", "lastName": "Fauci" } ], "abstractNote": "This study was undertaken to determine the proportions and in vitro immune capacities of lymphocyte populations in the bone marrows of normal humans. Relatively pure mononuclear cell suspensions were obtained from bone marrow aspirates by linear sucrose gradient centrifugations. Simultaneous peripheral blood and bone marrow specimens from each individual were assayed for lymphocyte surface markers and mitogen responsiveness. Maximal possible contamination of bone marrow aspirates by peripheral blood was determined by performing aspirates on individuals who had received 51chromium-labeled autologous erythrocytes. Rhymus-derived (T) lymphocytes, as determined by the sheep red blood cell (E) rosette assay, comprised 8.6-(plus or minus 1.6)% of the total bone marrow lymphocyte pool. Bone marrow-derived (B) lymphocytes, as determined by the presence of a complement receptor, made up 15.4-(plus or minus 1.9)% of the lymphocyte pool whereas 74.6 (plus or minus 2.4)% of mononuclear cells lacked easily detectable surface markers. These findings could not be explained by contamination with peripheral blood lymphocytes since contamination was corrected for in the calculations. Lymphocyte-enriched suspensions of bone marrow cells responded to stimulation with phytohemagglutinin, concanalin A, and particularly pokeweed mitogen. In vitro incubations of bone marrow and peripheral blood lymphocytes with tritiated thymidine followed by determinations of E and erythrocyte antibody complement (EAC) rosettes were performed. Simultaneous rosetteradioautographs demonstrated that the proliferative potential of bone marrow B lymphocytes was greater than peripheral blood B lymphocytes (P less than 0.01). On the other hand, the proliferative potential of bone marrow T lymphocytes was the same as that of peripheral blood T lymphocytes. These findings demonstrate that in addition to containing B lymphocytes the normal bone marrow contains a small fraction of T lymphocytes similar to the mature T lymphocyte pool found in the peripheral blood. These T cells most probably enter the bone marrow parenchyma as part of the normal recirculating lymphocyte pool.", "publicationTitle": "The Journal of clinical investigation", "publisher": "", "place": "United States", "date": "1975 Jul", "volume": "56", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "98-110", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Clin Invest", "DOI": "10.1172/JCI108085", "citationKey": "", "url": "", "accessDate": "", "PMID": "1079808", "PMCID": "PMC436560", "ISSN": "0021-9738", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Bone Marrow Cells" }, { "tag": "*Bone Marrow/immunology" }, { "tag": "*Lymphocytes/immunology" }, { "tag": "Adult" }, { "tag": "Animals" }, { "tag": "Autoradiography" }, { "tag": "B-Lymphocytes/immunology" }, { "tag": "Centrifugation, Zonal" }, { "tag": "Concanavalin A/pharmacology" }, { "tag": "Erythrocytes/immunology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Lectins/pharmacology" }, { "tag": "Lymphocyte Activation" }, { "tag": "Male" }, { "tag": "Mitogens/pharmacology" }, { "tag": "Sheep/immunology" }, { "tag": "T-Lymphocytes/immunology" }, { "tag": "Thymidine/metabolism" }, { "tag": "Tritium" } ], "collections": [ "AAUDSXFB" ], "relations": {}, "dateAdded": "2026-03-14T03:00:15Z", "dateModified": "2026-03-14T03:00:15Z" } } ]