[ { "key": "MB3BTW6R", "version": 206451, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/MB3BTW6R", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/MB3BTW6R", "type": "text/html" } }, "meta": { "creatorSummary": "Ferák et al.", "parsedDate": "1981-07", "numChildren": 0 }, "data": { "key": "MB3BTW6R", "version": 206451, "itemType": "journalArticle", "title": "[Population-genetical structure of a region with increased occurrence of Creutzfeldt-Jakob disease (author's transl)].", "creators": [ { "creatorType": "author", "firstName": "V.", "lastName": "Ferák" }, { "creatorType": "author", "firstName": "Z.", "lastName": "Kroupová" }, { "creatorType": "author", "firstName": "V.", "lastName": "Mayer" } ], "abstractNote": "", "publicationTitle": "Bratislavske lekarske listy", "publisher": "", "place": "Germany", "date": "1981 Jul", "volume": "76", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "35-44", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Bratisl Lek Listy", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "7020883", "PMCID": "", "ISSN": "0006-9248", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "slo", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Consanguinity" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*genetics" }, { "tag": "Czechoslovakia" }, { "tag": "Humans" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "H9Q676M7", "version": 206450, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/H9Q676M7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/H9Q676M7", "type": "text/html" } }, "meta": { "creatorSummary": "Mitrová et al.", "parsedDate": "1991-09", "numChildren": 0 }, "data": { "key": "H9Q676M7", "version": 206450, "itemType": "journalArticle", "title": "Focal accumulation of CJD in Slovakia: retrospective investigation of a new rural familial cluster.", "creators": [ { "creatorType": "author", "firstName": "E.", "lastName": "Mitrová" }, { "creatorType": "author", "firstName": "P.", "lastName": "Brown" }, { "creatorType": "author", "firstName": "D.", "lastName": "Hroncová" }, { "creatorType": "author", "firstName": "M.", "lastName": "Tatara" }, { "creatorType": "author", "firstName": "J.", "lastName": "Zilák" } ], "abstractNote": "", "publicationTitle": "European journal of epidemiology", "publisher": "", "place": "Netherlands", "date": "1991 Sep", "volume": "7", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "487-489", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Eur J Epidemiol", "DOI": "10.1007/BF00143126", "citationKey": "", "url": "", "accessDate": "", "PMID": "1761105", "PMCID": "", "ISSN": "0393-2990", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Cluster Analysis" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology" }, { "tag": "Czechoslovakia/epidemiology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Pedigree" }, { "tag": "Retrospective Studies" }, { "tag": "Rural Population" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "EXCPJRPV", "version": 206449, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/EXCPJRPV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/EXCPJRPV", "type": "text/html" } }, "meta": { "creatorSummary": "Bucy", "parsedDate": "1977-09", "numChildren": 0 }, "data": { "key": "EXCPJRPV", "version": 206449, "itemType": "journalArticle", "title": "Neurosurgical transmission of neurological diseases.", "creators": [ { "creatorType": "author", "firstName": "P. C.", "lastName": "Bucy" } ], "abstractNote": "", "publicationTitle": "Surgical neurology", "publisher": "", "place": "United States", "date": "1977 Sep", "volume": "8", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "166", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Surg Neurol", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "331525", "PMCID": "", "ISSN": "0090-3019", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Creutzfeldt-Jakob Syndrome/surgery/*transmission" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Surgical Procedures, Operative/*adverse effects" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "Z5CGZZJU", "version": 206448, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/Z5CGZZJU", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/Z5CGZZJU", "type": "text/html" } }, "meta": { "creatorSummary": "Oppenheimer", "parsedDate": "1985-04", "numChildren": 0 }, "data": { "key": "Z5CGZZJU", "version": 206448, "itemType": "journalArticle", "title": "Oncogenes in scrapie and Creutzfeldt-Jacob disease.", "creators": [ { "creatorType": "author", "firstName": "S. J.", "lastName": "Oppenheimer" } ], "abstractNote": "", "publicationTitle": "Journal of the Royal Society of Medicine", "publisher": "", "place": "England", "date": "1985 Apr", "volume": "78", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "347", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J R Soc Med", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "3884811", "PMCID": "PMC1289692", "ISSN": "0141-0768", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Oncogenes" }, { "tag": "Animals" }, { "tag": "Creutzfeldt-Jakob Syndrome/*genetics" }, { "tag": "Humans" }, { "tag": "Scrapie/*genetics" }, { "tag": "Sheep" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "J2BVSCUX", "version": 206447, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/J2BVSCUX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/J2BVSCUX", "type": "text/html" } }, "meta": { "creatorSummary": "Ridley et al.", "parsedDate": "1985-11", "numChildren": 0 }, "data": { "key": "J2BVSCUX", "version": 206447, "itemType": "journalArticle", "title": "Virogenes in scrapie and Creutzfeldt-Jakob disease.", "creators": [ { "creatorType": "author", "firstName": "R. M.", "lastName": "Ridley" }, { "creatorType": "author", "firstName": "H. F.", "lastName": "Baker" }, { "creatorType": "author", "firstName": "T. J.", "lastName": "Crow" } ], "abstractNote": "", "publicationTitle": "Journal of the Royal Society of Medicine", "publisher": "", "place": "England", "date": "1985 Nov", "volume": "78", "issue": "11", "section": "", "partNumber": "", "partTitle": "", "pages": "970", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J R Soc Med", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "3906122", "PMCID": "PMC1290018", "ISSN": "0141-0768", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Age Factors" }, { "tag": "Animals" }, { "tag": "Creutzfeldt-Jakob Syndrome/*genetics" }, { "tag": "Genes" }, { "tag": "Humans" }, { "tag": "Middle Aged" }, { "tag": "Scrapie/*genetics" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "EAY4V43C", "version": 206446, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/EAY4V43C", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/EAY4V43C", "type": "text/html" } }, "meta": { "creatorSummary": "Fieschi et al.", "parsedDate": "1983-04", "numChildren": 0 }, "data": { "key": "EAY4V43C", "version": 206446, "itemType": "journalArticle", "title": "Creutzfeld-Jakob disease in the province of Siena: two cases transmitted to monkeys.", "creators": [ { "creatorType": "author", "firstName": "C.", "lastName": "Fieschi" }, { "creatorType": "author", "firstName": "F.", "lastName": "Orzi" }, { "creatorType": "author", "firstName": "M.", "lastName": "Pocchiari" }, { "creatorType": "author", "firstName": "M.", "lastName": "Nardini" }, { "creatorType": "author", "firstName": "F.", "lastName": "Rocchi" }, { "creatorType": "author", "firstName": "D.", "lastName": "Asher" }, { "creatorType": "author", "firstName": "C.", "lastName": "Gibbs" }, { "creatorType": "author", "firstName": "D.", "lastName": "Gajdusek" } ], "abstractNote": "Two cases of histopathologically documented Creutzfeldt-Jakob disease were observed in the same area of the province of Siena in 1974-1975. The transmission of the disease was obtained through brain homogenates and lymphnodes in one of the two cases. This confirms that the agent is present in other tissues besides the brain and underlines further the analogies between Creutzfeld-Jakob disease and scrapie.", "publicationTitle": "Italian journal of neurological sciences", "publisher": "", "place": "Italy", "date": "1983 Apr", "volume": "4", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "61-64", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Ital J Neurol Sci", "DOI": "10.1007/BF02043438", "citationKey": "", "url": "", "accessDate": "", "PMID": "6345460", "PMCID": "", "ISSN": "0392-0461", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Cebidae/*microbiology" }, { "tag": "Cebus/microbiology" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*transmission" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Italy" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Saimiri/microbiology" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "THNP6GPV", "version": 206445, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/THNP6GPV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/THNP6GPV", "type": "text/html" } }, "meta": { "creatorSummary": "Akai et al.", "parsedDate": "1989", "numChildren": 0 }, "data": { "key": "THNP6GPV", "version": 206445, "itemType": "journalArticle", "title": "Creutzfeldt-Jakob disease in Japan: an epidemiological study done in a select prefecture between 1976 and 1986.", "creators": [ { "creatorType": "author", "firstName": "J.", "lastName": "Akai" }, { "creatorType": "author", "firstName": "O.", "lastName": "Ishihara" }, { "creatorType": "author", "firstName": "S.", "lastName": "Higuchi" } ], "abstractNote": "An epidemiological study was performed with respect to Creutzfeldt-Jakob disease in a designated area in Japan. The subjects were observed in a small rural prefecture where the population generally remains within a limited radius throughout their lives. The patients' life-styles in each area were investigated in detail. Nine cases appeared in 11 years; 6 were definitive and 3 probable. They were all of the subacute type; there were no noteworthy sexual differences, age of onset, course and/or past histories. Three of the nine cases came from two families; the relationship between familial and isolated cases was examined. Revealed facts and time-space clustering were investigated statistically, but no indication of natural transmission was observable.", "publicationTitle": "Neuroepidemiology", "publisher": "", "place": "Switzerland", "date": "1989", "volume": "8", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "32-37", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Neuroepidemiology", "DOI": "10.1159/000110162", "citationKey": "", "url": "", "accessDate": "", "PMID": "2643060", "PMCID": "", "ISSN": "0251-5350", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Aged" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Japan" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Rural Population" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "XC4Q2GCZ", "version": 206444, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/XC4Q2GCZ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/XC4Q2GCZ", "type": "text/html" } }, "meta": { "creatorSummary": "Cathala et al.", "parsedDate": "1980-09", "numChildren": 0 }, "data": { "key": "XC4Q2GCZ", "version": 206444, "itemType": "journalArticle", "title": "Familial Creutzfeldt-Jakob disease. Autosomal dominance in 14 members over 3 generations.", "creators": [ { "creatorType": "author", "firstName": "F.", "lastName": "Cathala" }, { "creatorType": "author", "firstName": "J.", "lastName": "Chatelain" }, { "creatorType": "author", "firstName": "P.", "lastName": "Brown" }, { "creatorType": "author", "firstName": "M.", "lastName": "Dumas" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Gajdusek" } ], "abstractNote": "Discovery oa a second affected branch of a family with transmitted Creutzfeldt-Jakob disease (CJD), originally reported by Buge et al. in 1978, brings the total number of cases to 14 in 3 generations, with at least 20 members of the next young adult generation presently at risk. Complete segregation of the illness to the descendants of these 2 branches, with no skipped generations, and an overall frequency of CJD in affected sibships of 56%, clearly defines a pattern of autosomal dominance. The disease is indifferent to sex, either in terms of affected members (8 males and 6 females) or of lineage (3 fathers and 3 mothers). Acquisition of CJD virus from a point source contamination is unlikely, and case-to-case transmission, if it occurred, would have required an average minimum incubation period of 17 years.", "publicationTitle": "Journal of the neurological sciences", "publisher": "", "place": "Netherlands", "date": "1980 Sep", "volume": "47", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "343-351", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Neurol Sci", "DOI": "10.1016/0022-510x(80)90087-8", "citationKey": "", "url": "", "accessDate": "", "PMID": "6999131", "PMCID": "", "ISSN": "0022-510X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Creutzfeldt-Jakob Syndrome/etiology/*genetics" }, { "tag": "Genes, Dominant" }, { "tag": "Humans" }, { "tag": "Pedigree" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "TEAR5FCB", "version": 206443, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/TEAR5FCB", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/TEAR5FCB", "type": "text/html" } }, "meta": { "creatorSummary": "Mitrová et al.", "parsedDate": "1986-08", "numChildren": 0 }, "data": { "key": "TEAR5FCB", "version": 206443, "itemType": "journalArticle", "title": "[An analysis of cases of familial Creutzfeldt-Jakob disease in Slovakia].", "creators": [ { "creatorType": "author", "firstName": "E.", "lastName": "Mitrová" }, { "creatorType": "author", "firstName": "L.", "lastName": "Czuhajová" }, { "creatorType": "author", "firstName": "E.", "lastName": "Gajdos" }, { "creatorType": "author", "firstName": "M.", "lastName": "Hovádová" }, { "creatorType": "author", "firstName": "A.", "lastName": "Nagy" }, { "creatorType": "author", "firstName": "J.", "lastName": "Rattaj" } ], "abstractNote": "", "publicationTitle": "Bratislavske lekarske listy", "publisher": "", "place": "Germany", "date": "1986 Aug", "volume": "86", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "202-210", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Bratisl Lek Listy", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "3530384", "PMCID": "", "ISSN": "0006-9248", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "slo", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Aged" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/etiology/*genetics" }, { "tag": "Czechoslovakia" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "RCW7DIZZ", "version": 206442, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/RCW7DIZZ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/RCW7DIZZ", "type": "text/html" } }, "meta": { "creatorSummary": "Bobowick et al.", "parsedDate": "1973-11", "numChildren": 0 }, "data": { "key": "RCW7DIZZ", "version": 206442, "itemType": "journalArticle", "title": "Creutzfeldt-Jakob disease: a case-control study.", "creators": [ { "creatorType": "author", "firstName": "A. R.", "lastName": "Bobowick" }, { "creatorType": "author", "firstName": "J. A.", "lastName": "Brody" }, { "creatorType": "author", "firstName": "M. R.", "lastName": "Matthews" }, { "creatorType": "author", "firstName": "R.", "lastName": "Roos" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Gajdusek" } ], "abstractNote": "", "publicationTitle": "American journal of epidemiology", "publisher": "", "place": "United States", "date": "1973 Nov", "volume": "98", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "381-394", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Am J Epidemiol", "DOI": "10.1093/oxfordjournals.aje.a121567", "citationKey": "", "url": "", "accessDate": "", "PMID": "4583406", "PMCID": "", "ISSN": "0002-9262", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Canada" }, { "tag": "Creutzfeldt-Jakob Syndrome/classification/complications/*epidemiology/etiology/genetics/immunology" }, { "tag": "Epidemiologic Methods" }, { "tag": "Feeding Behavior" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Occupations" }, { "tag": "Pedigree" }, { "tag": "Residence Characteristics" }, { "tag": "Seasons" }, { "tag": "Socioeconomic Factors" }, { "tag": "Time Factors" }, { "tag": "United States" }, { "tag": "Virus Diseases/complications" }, { "tag": "Zoonoses/epidemiology" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "4KVDTJ84", "version": 206441, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/4KVDTJ84", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/4KVDTJ84", "type": "text/html" } }, "meta": { "creatorSummary": "Will and Matthews", "parsedDate": "1982-03", "numChildren": 0 }, "data": { "key": "4KVDTJ84", "version": 206441, "itemType": "journalArticle", "title": "Evidence for case-to-case transmission of Creutzfeldt-Jakob disease.", "creators": [ { "creatorType": "author", "firstName": "R. G.", "lastName": "Will" }, { "creatorType": "author", "firstName": "W. B.", "lastName": "Matthews" } ], "abstractNote": "Three cases of probable iatrogenic transmission of Creutzfeldt-Jakob disease by neurosurgery are detailed together with a cluster of three cases in Eastern England possibly connected by dental procedures, and the development of Creutzfeldt-Jakob disease in a patient who had been in social contact with a familial case.", "publicationTitle": "Journal of neurology, neurosurgery, and psychiatry", "publisher": "", "place": "England", "date": "1982 Mar", "volume": "45", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "235-238", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Neurol Neurosurg Psychiatry", "DOI": "10.1136/jnnp.45.3.235", "citationKey": "", "url": "", "accessDate": "", "PMID": "7045290", "PMCID": "PMC491343", "ISSN": "0022-3050 1468-330X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Aged" }, { "tag": "Cerebral Ventriculography" }, { "tag": "Creutzfeldt-Jakob Syndrome/genetics/*transmission" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Iatrogenic Disease" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Neurosurgery" }, { "tag": "Surgical Procedures, Operative/adverse effects" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "WYPJ6TYM", "version": 206440, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/WYPJ6TYM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/WYPJ6TYM", "type": "text/html" } }, "meta": { "creatorSummary": "Neugut et al.", "parsedDate": "1979-02", "numChildren": 0 }, "data": { "key": "WYPJ6TYM", "version": 206440, "itemType": "journalArticle", "title": "Creutzfeldt-Jakob disease: familial clustering among Libyan-born Israelis.", "creators": [ { "creatorType": "author", "firstName": "R. H.", "lastName": "Neugut" }, { "creatorType": "author", "firstName": "A. I.", "lastName": "Neugut" }, { "creatorType": "author", "firstName": "E.", "lastName": "Kahana" }, { "creatorType": "author", "firstName": "Z.", "lastName": "Stein" }, { "creatorType": "author", "firstName": "M.", "lastName": "Alter" } ], "abstractNote": "Creutzfeldt-Jakob disease was studied among Libyan-born Israelis, in whom the disease appears with unusual frequency. Interviews with relatives of deceased victims revealed statistically significant clustering within families. The results suggest either a common source of exposure or a genetic influence on susceptibility to the virus.", "publicationTitle": "Neurology", "publisher": "", "place": "United States", "date": "1979 Feb", "volume": "29", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "225-231", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Neurology", "DOI": "10.1212/wnl.29.2.225", "citationKey": "", "url": "", "accessDate": "", "PMID": "372840", "PMCID": "", "ISSN": "0028-3878", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Jews" }, { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Creutzfeldt-Jakob Syndrome/etiology/*genetics/transmission" }, { "tag": "Environment" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Israel" }, { "tag": "Libya/ethnology" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Pedigree" }, { "tag": "Probability" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "NVB6HVNP", "version": 206439, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/NVB6HVNP", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/NVB6HVNP", "type": "text/html" } }, "meta": { "creatorSummary": "Haltia et al.", "parsedDate": "1979-08", "numChildren": 0 }, "data": { "key": "NVB6HVNP", "version": 206439, "itemType": "journalArticle", "title": "Familial Creutzfeldt-Jakob disease.", "creators": [ { "creatorType": "author", "firstName": "M.", "lastName": "Haltia" }, { "creatorType": "author", "firstName": "J.", "lastName": "Kovanen" }, { "creatorType": "author", "firstName": "H.", "lastName": "Van Crevel" }, { "creatorType": "author", "firstName": "G. T.", "lastName": "Bots" }, { "creatorType": "author", "firstName": "S.", "lastName": "Stefanko" } ], "abstractNote": "A Finnish family is described with 9 cases of presenile dementia in 3 generations. The mean age at onset was 52 years (range 46--62 years). Progressive dementia, upper motor neuron signs, muscular rigidity, and twitching, irregular tremors were consistent features in the 6 clinically investigated patients and were associated with spongiform change in the cerebral cortex of one autopsy and two brain biopsy cases. The EEG showed progressive slowing without the occurrence of repetitive high-voltage complexes at any stage of the disease. The average duration of the disease (21 months, range 11--36 months) was longer than in the sporadic form of CJD. The occurrence of CJD within this family follows a pattern consistent with an autosomal dominant mode of inheritance, suggesting the possibility of vertical transmission of the presumptive causative agent for example by genomic integration or transplacental passage. However, the occurrence of the disease only through the paternal line of relationships and the presence of a discordant twin pair argue strongly against transplacental passage or transmission via mother's milk. Simple contact infection also seems unlikely, as conjugal cases were not found among the 7 married patients. The interval between the death of the last affected member in generation IV and the time of onset of the disease in the first affected member of generation V was 10 years. Thus setting a minimum incubation period if case-to-case transmission were occurring. To evaluate the role of a genetically determined susceptibility to infection studies on the HLA antigens and other genetic markers are in progress.", "publicationTitle": "Journal of the neurological sciences", "publisher": "", "place": "Netherlands", "date": "1979 Aug", "volume": "42", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "381-389", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Neurol Sci", "DOI": "10.1016/0022-510x(79)90171-0", "citationKey": "", "url": "", "accessDate": "", "PMID": "390100", "PMCID": "", "ISSN": "0022-510X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Creutzfeldt-Jakob Syndrome/etiology/*genetics/transmission" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "JQWCPRXM", "version": 206438, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/JQWCPRXM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/JQWCPRXM", "type": "text/html" } }, "meta": { "creatorSummary": "Ferak et al.", "parsedDate": "1981-02-14", "numChildren": 0 }, "data": { "key": "JQWCPRXM", "version": 206438, "itemType": "journalArticle", "title": "Are population-genetic mechanisms responsible for clustering of cases of Creutzfeldt-Jakob disease?", "creators": [ { "creatorType": "author", "firstName": "V.", "lastName": "Ferak" }, { "creatorType": "author", "firstName": "Z.", "lastName": "Kroupova" }, { "creatorType": "author", "firstName": "V.", "lastName": "Mayer" } ], "abstractNote": "", "publicationTitle": "British medical journal (Clinical research ed.)", "publisher": "", "place": "England", "date": "1981 Feb 14", "volume": "282", "issue": "6263", "section": "", "partNumber": "", "partTitle": "", "pages": "521-522", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Br Med J (Clin Res Ed)", "DOI": "10.1136/bmj.282.6263.521-a", "citationKey": "", "url": "", "accessDate": "", "PMID": "6780108", "PMCID": "PMC1504344", "ISSN": "0267-0623", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Gene Frequency" }, { "tag": "Consanguinity" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*genetics" }, { "tag": "Czechoslovakia" }, { "tag": "Humans" }, { "tag": "Marriage" }, { "tag": "Space-Time Clustering" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "FTC3ZX57", "version": 206437, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/FTC3ZX57", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/FTC3ZX57", "type": "text/html" } }, "meta": { "creatorSummary": "Matthews", "parsedDate": "1975-03", "numChildren": 0 }, "data": { "key": "FTC3ZX57", "version": 206437, "itemType": "journalArticle", "title": "Epidemiology of Creutzfeldt-Jakob disease in England and Wales.", "creators": [ { "creatorType": "author", "firstName": "W. B.", "lastName": "Matthews" } ], "abstractNote": "Some aspects of the epidemiology of Creutzfeldt-Jakob disease in England and Wales in the decade 1964-73 were studied with the object of detecting evidence of natural transmission of this slow virus encephalopathy. Some geographical clustering and possibility of contact between cases was found.", "publicationTitle": "Journal of neurology, neurosurgery, and psychiatry", "publisher": "", "place": "England", "date": "1975 Mar", "volume": "38", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "210-213", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Neurol Neurosurg Psychiatry", "DOI": "10.1136/jnnp.38.3.210", "citationKey": "", "url": "", "accessDate": "", "PMID": "1097599", "PMCID": "PMC491897", "ISSN": "0022-3050 1468-330X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Cerebrovascular Disorders/complications" }, { "tag": "Craniocerebral Trauma/complications" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/transmission" }, { "tag": "England" }, { "tag": "Feeding Behavior" }, { "tag": "Female" }, { "tag": "Ferrets" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Rural Population" }, { "tag": "Trigeminal Neuralgia/surgery" }, { "tag": "Urban Population" }, { "tag": "Wales" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "K7T4UPBU", "version": 206436, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/K7T4UPBU", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/K7T4UPBU", "type": "text/html" } }, "meta": { "creatorSummary": "Goldfarb et al.", "parsedDate": "1990-08-25", "numChildren": 0 }, "data": { "key": "K7T4UPBU", "version": 206436, "itemType": "journalArticle", "title": "Mutation in codon 200 of scrapie amyloid protein gene in two clusters of Creutzfeldt-Jakob disease in Slovakia.", "creators": [ { "creatorType": "author", "firstName": "L. G.", "lastName": "Goldfarb" }, { "creatorType": "author", "firstName": "E.", "lastName": "Mitrová" }, { "creatorType": "author", "firstName": "P.", "lastName": "Brown" }, { "creatorType": "author", "firstName": "B. K.", "lastName": "Toh" }, { "creatorType": "author", "firstName": "D. C.", "lastName": "Gajdusek" } ], "abstractNote": "", "publicationTitle": "Lancet (London, England)", "publisher": "", "place": "England", "date": "1990 Aug 25", "volume": "336", "issue": "8713", "section": "", "partNumber": "", "partTitle": "", "pages": "514-515", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Lancet", "DOI": "10.1016/0140-6736(90)92073-q", "citationKey": "", "url": "", "accessDate": "", "PMID": "1975028", "PMCID": "", "ISSN": "0140-6736", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Mutation" }, { "tag": "Aged" }, { "tag": "Codon/*genetics" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*genetics" }, { "tag": "Czechoslovakia/epidemiology" }, { "tag": "DNA, Viral/analysis" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Nerve Tissue Proteins/*genetics" }, { "tag": "PrP 27-30 Protein" }, { "tag": "RNA, Messenger/*genetics" }, { "tag": "Space-Time Clustering" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "ED7T3U75", "version": 206435, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/ED7T3U75", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/ED7T3U75", "type": "text/html" } }, "meta": { "creatorSummary": "Barash and Dziura", "parsedDate": "2007-07", "numChildren": 0 }, "data": { "key": "ED7T3U75", "version": 206435, "itemType": "journalArticle", "title": "A systematic review of sporadic Creutzfeldt-Jakob disease clusters: do clinical, epidemiologic, and genetic features reflect infectious clustering mechanisms?", "creators": [ { "creatorType": "author", "firstName": "Jed A.", "lastName": "Barash" }, { "creatorType": "author", "firstName": "James", "lastName": "Dziura" } ], "abstractNote": "BACKGROUND: While the cause of sporadic Creutzfeldt-Jakob disease (sCJD) is unknown, case clustering could suggest infectious transmission in some instances. METHODS: Publications of sCJD clusters were systematically identified and pooled to determine if their clinical, epidemiologic, and genetic features reflected potential infectious clustering mechanisms. RESULTS: The search yielded five clusters involving 23 cases. Most notably, among 12 cases with reported residential histories, patients lived for a median of 30.0 years (25th percentile: 26.5 years; 75th percentile: 51.0 years) in their respective cluster regions. Of 19 cases that underwent genotyping for polymorphic codon 129, seventeen were methionine homozygotes (89.5%; 95% CI 67.4-98.3%); none were heterozygous. CONCLUSIONS: Prolonged residency duration and Prnp codon 129 methionine homozygosity may be consistent with underlying disease-clustering mechanisms, although larger, controlled investigations might help to exclude the possibility that these findings reflect the normal distribution of these features among relevant comparison populations.", "publicationTitle": "Connecticut medicine", "publisher": "", "place": "United States", "date": "2007 Jun-Jul", "volume": "71", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "333-337", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Conn Med", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "17619468", "PMCID": "", "ISSN": "0010-6178", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Cluster Analysis" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/genetics/transmission" }, { "tag": "Genotype" }, { "tag": "Humans" }, { "tag": "Residence Characteristics" }, { "tag": "Risk Factors" }, { "tag": "Time Factors" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "WQCXCXJ9", "version": 206434, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/WQCXCXJ9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/WQCXCXJ9", "type": "text/html" } }, "meta": { "creatorSummary": "Lo Russo et al.", "parsedDate": "1980-06", "numChildren": 0 }, "data": { "key": "WQCXCXJ9", "version": 206434, "itemType": "journalArticle", "title": "Creutzfeldt-Jakob disease and sheep brain. A report from central and Southern Italy.", "creators": [ { "creatorType": "author", "firstName": "F.", "lastName": "Lo Russo" }, { "creatorType": "author", "firstName": "G.", "lastName": "Neri" }, { "creatorType": "author", "firstName": "L.", "lastName": "Figà-Talamanca" } ], "abstractNote": "The places of origin of 7 out of 8 patients with CJD coincide with the distribution of sheep-rearing in central and southern Italy, confirming the suggested link between this disease and eating and-or handling sheep CNS tissue. Since 6 of the 8 cases were women, it seems more likely that the virus responsible for CJD enters the body through a break in the skin of the hands and forearms in the process of foodhandling rather than via the Digestive tract. This aspect should be borne in mind when investigating the problems of CJD transmission.", "publicationTitle": "Italian journal of neurological sciences", "publisher": "", "place": "Italy", "date": "1980 Jun", "volume": "1", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "171-174", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Ital J Neurol Sci", "DOI": "10.1007/BF02335847", "citationKey": "", "url": "", "accessDate": "", "PMID": "7042643", "PMCID": "", "ISSN": "0392-0461", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Animal Husbandry" }, { "tag": "*Food Handling" }, { "tag": "*Sheep" }, { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Brain" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*transmission" }, { "tag": "Diet/adverse effects" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Italy" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Sheep Diseases/*transmission" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "4RM3EKR2", "version": 206433, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/4RM3EKR2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/4RM3EKR2", "type": "text/html" } }, "meta": { "creatorSummary": "Bacchetti", "parsedDate": "2003-12", "numChildren": 0 }, "data": { "key": "4RM3EKR2", "version": 206433, "itemType": "journalArticle", "title": "Age and variant Creutzfeldt-Jakob disease.", "creators": [ { "creatorType": "author", "firstName": "Peter", "lastName": "Bacchetti" } ], "abstractNote": "The young and stable median age of those who die of variant Creutzfeldt-Jakob disease has been attributed to age-dependent infection rates. This analysis shows that an influence of age on risk for death after infection better explains age patterns, suggesting that biologic factors peaking in the third decade of life may hasten disease.", "publicationTitle": "Emerging infectious diseases", "publisher": "", "place": "United States", "date": "2003 Dec", "volume": "9", "issue": "12", "section": "", "partNumber": "", "partTitle": "", "pages": "1611-1612", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Emerg Infect Dis", "DOI": "10.3201/eid0912.030361", "citationKey": "", "url": "", "accessDate": "", "PMID": "14720404", "PMCID": "", "ISSN": "1080-6040", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Age Factors" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/mortality" }, { "tag": "Humans" }, { "tag": "Models, Biological" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "35EFWLQA", "version": 206432, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/35EFWLQA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/35EFWLQA", "type": "text/html" } }, "meta": { "creatorSummary": "Cathala et al.", "parsedDate": "1985-06", "numChildren": 0 }, "data": { "key": "35EFWLQA", "version": 206432, "itemType": "journalArticle", "title": "Failure to detect scrapie virus in sheep at slaughter in a highly endemic region of France.", "creators": [ { "creatorType": "author", "firstName": "F.", "lastName": "Cathala" }, { "creatorType": "author", "firstName": "P.", "lastName": "Brown" }, { "creatorType": "author", "firstName": "F.", "lastName": "Gray" }, { "creatorType": "author", "firstName": "M.", "lastName": "Sulima" }, { "creatorType": "author", "firstName": "J.", "lastName": "Chatelain" }, { "creatorType": "author", "firstName": "C. J. Jr", "lastName": "Gibbs" } ], "abstractNote": "A study was carried out in a sheep slaughterhouse located in a region of France where scrapie has been endemic for several decades. Neuropathological examination of 63 randomly selected lambs and adult sheep revealed no scrapie-related abnormalities, and inoculation of mice with brain, tonsil, lateropharyngeal ganglia, and intestine from the same animals did not transmit scrapie. The failure to detect any evidence of scrapie infection in commercially-bred sheep, the absence of an increased mortality rate for human CJD in the surrounding consumer region, and the absence of a single case of CJD among slaughterhouse personnel, do not support the hypothesis that exposure to potentially scrapie-contaminated products is responsible for CJD in humans.", "publicationTitle": "European journal of epidemiology", "publisher": "", "place": "Netherlands", "date": "1985 Jun", "volume": "1", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "90-93", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Eur J Epidemiol", "DOI": "10.1007/BF00141798", "citationKey": "", "url": "", "accessDate": "", "PMID": "3939516", "PMCID": "", "ISSN": "0393-2990", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "*Abattoirs" }, { "tag": "Animals" }, { "tag": "Brain/pathology" }, { "tag": "Creutzfeldt-Jakob Syndrome/transmission" }, { "tag": "France" }, { "tag": "Humans" }, { "tag": "Mice" }, { "tag": "Prions/*isolation & purification" }, { "tag": "Scrapie/*epidemiology" }, { "tag": "Sheep/*microbiology" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "T7IDLY6D", "version": 206431, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/T7IDLY6D", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/T7IDLY6D", "type": "text/html" } }, "meta": { "creatorSummary": "Ward et al.", "parsedDate": "2002-08-27", "numChildren": 0 }, "data": { "key": "T7IDLY6D", "version": 206431, "itemType": "journalArticle", "title": "Sporadic Creutzfeldt-Jakob disease and surgery: a case-control study using community controls.", "creators": [ { "creatorType": "author", "firstName": "H. J. T.", "lastName": "Ward" }, { "creatorType": "author", "firstName": "D.", "lastName": "Everington" }, { "creatorType": "author", "firstName": "E. A.", "lastName": "Croes" }, { "creatorType": "author", "firstName": "A.", "lastName": "Alperovitch" }, { "creatorType": "author", "firstName": "N.", "lastName": "Delasnerie-Lauprêtre" }, { "creatorType": "author", "firstName": "I.", "lastName": "Zerr" }, { "creatorType": "author", "firstName": "S.", "lastName": "Poser" }, { "creatorType": "author", "firstName": "C. M.", "lastName": "van Duijn" } ], "abstractNote": "BACKGROUND: The cause of sporadic Creutzfeldt-Jakob disease (CJD) is unknown. Previous studies found a link with a history of surgery but had methodologic problems. OBJECTIVE: To help elucidate medical and associated risk factors for sporadic CJD as part of the 1993 to 1995 European Union collaborative studies of CJD. METHODS: Medical and associated risk factors from 326 patients with sporadic CJD, taken from population-based studies performed between 1993 and 1995 in France, Germany, the Netherlands, and the UK, were compared with 326 community controls recruited by telephone in 2000. RESULTS: A history of surgery was significantly associated with the risk of sporadic CJD (odds ratio [OR]: 1.8; 95% CI: 1.2 to 2.6), which was not dependent on the number of surgical procedures, and was stronger in females (OR: 2.5; 95% CI: 1.5 to 4.0). Gynecologic (OR: 1.5; 95% CI: 1.0 to 2.3) and \"other\" operations (any operation other than neurologic, eye, ear, gallbladder, gastrointestinal, and gynecologic operations, tonsillectomy, and appendectomy) (OR: 1.5; 95% CI: 1.1 to 2.1) were associated with risk of CJD. Tonsillectomy (OR: 0.3; 95% CI: 0.2 to 0.5) and appendectomy (OR: 0.6; 95% CI: 0.4 to 0.8) were observed less frequently in cases. An increased risk was also found with a history of ear piercing in females (OR: 1.6; 95% CI: 1.1 to 2.5) and psychiatric visit(s) (OR: 2.6; 95% CI: 1.5 to 4.3). CONCLUSIONS: These results support the hypothesis that cases of sporadic CJD may result from hitherto unrecognized surgical contamination events. However, because of the limits of the study design, the rarity of the disease, and the potential for bias, the results should be interpreted with caution.", "publicationTitle": "Neurology", "publisher": "", "place": "United States", "date": "2002 Aug 27", "volume": "59", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "543-548", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Neurology", "DOI": "10.1212/wnl.59.4.543", "citationKey": "", "url": "", "accessDate": "", "PMID": "12196646", "PMCID": "", "ISSN": "0028-3878", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Aged" }, { "tag": "Case-Control Studies" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/*etiology" }, { "tag": "Female" }, { "tag": "France/epidemiology" }, { "tag": "Germany/epidemiology" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Netherlands/epidemiology" }, { "tag": "Odds Ratio" }, { "tag": "Registries/statistics & numerical data" }, { "tag": "Risk Assessment" }, { "tag": "Risk Factors" }, { "tag": "Sex Distribution" }, { "tag": "Sex Factors" }, { "tag": "Surgical Procedures, Operative/*adverse effects/statistics & numerical data" }, { "tag": "United Kingdom/epidemiology" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "33JNYH6E", "version": 206430, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/33JNYH6E", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/33JNYH6E", "type": "text/html" } }, "meta": { "creatorSummary": "Cousens et al.", "parsedDate": "1990-06", "numChildren": 0 }, "data": { "key": "33JNYH6E", "version": 206430, "itemType": "journalArticle", "title": "Geographical distribution of cases of Creutzfeldt-Jakob disease in England and Wales 1970-84.", "creators": [ { "creatorType": "author", "firstName": "S. N.", "lastName": "Cousens" }, { "creatorType": "author", "firstName": "R.", "lastName": "Harries-Jones" }, { "creatorType": "author", "firstName": "R.", "lastName": "Knight" }, { "creatorType": "author", "firstName": "R. G.", "lastName": "Will" }, { "creatorType": "author", "firstName": "P. G.", "lastName": "Smith" }, { "creatorType": "author", "firstName": "W. B.", "lastName": "Matthews" } ], "abstractNote": "Two hundred and sixty seven patients with a definite or probable diagnosis of Creutzfeldt-Jakob disease (CJD) were identified in an attempt to ascertain all cases of the disease in England and Wales in the period 1970-84. No evidence of space-time clustering of dates and places of onset was found for these cases. Two age- and sex-matched controls were selected for 72 of the 122 cases diagnosed in the period 1980-84 and life histories of places of residence were obtained for these cases and the controls. No evidence was found that cases had lived closer to each other than had controls at any time in their lives, except that there was an excess of cases born in London. The study does not provide supportive evidence for case-to-case transmission of CJD being an important component in the aetiology of the disease.", "publicationTitle": "Journal of neurology, neurosurgery, and psychiatry", "publisher": "", "place": "England", "date": "1990 Jun", "volume": "53", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "459-465", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Neurol Neurosurg Psychiatry", "DOI": "10.1136/jnnp.53.6.459", "citationKey": "", "url": "", "accessDate": "", "PMID": "2199610", "PMCID": "PMC1014203", "ISSN": "0022-3050 1468-330X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Case-Control Studies" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/transmission" }, { "tag": "Cross-Sectional Studies" }, { "tag": "England/epidemiology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Incidence" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Retrospective Studies" }, { "tag": "Risk Factors" }, { "tag": "Wales/epidemiology" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "2DIPDXC7", "version": 206429, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/2DIPDXC7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/2DIPDXC7", "type": "text/html" } }, "meta": { "creatorSummary": "Nakatani et al.", "parsedDate": "2015-04", "numChildren": 0 }, "data": { "key": "2DIPDXC7", "version": 206429, "itemType": "journalArticle", "title": "Temporal and regional variations in sporadic Creutzfeldt-Jakob disease in Japan, 2001-2010.", "creators": [ { "creatorType": "author", "firstName": "E.", "lastName": "Nakatani" }, { "creatorType": "author", "firstName": "T.", "lastName": "Nishimura" }, { "creatorType": "author", "firstName": "B.", "lastName": "Zhou" }, { "creatorType": "author", "firstName": "H.", "lastName": "Kaneda" }, { "creatorType": "author", "firstName": "S.", "lastName": "Teramukai" }, { "creatorType": "author", "firstName": "Y.", "lastName": "Nagai" }, { "creatorType": "author", "firstName": "M.", "lastName": "Fukushima" }, { "creatorType": "author", "firstName": "Y.", "lastName": "Kanatani" } ], "abstractNote": "The objective of this study was to examine temporal and regional variations of sporadic Creutzfeldt-Jakob disease (sCJD) in a retrospective study using Japanese national surveillance data from 2001 to 2010. We calculated the incidence of sCJD by age and sex, derived the standardized incidence in each of the 47 prefectures, and performed spatial disease clustering analysis. The average annual incidence of sCJD was 1.026 per million in men (637 patients) and 1.132 per million in women (733 patients), a significant sex difference after adjustment for age (P = 0.001). The ratios of familial CJD to sCJD apparently increased between 2001-2005 and 2006-2010, possibly as a result of the nationwide introduction of genetic testing after 2006. Based on the data of 2006-2010, certain geographical clusters of sCJD were identified. The incidence of sCJD was higher in several specific prefectures compared to the national average. Thus, sCJD appears to have regional variations, suggesting the existence of genetic or region-specific factors affecting the incidence of the disease.", "publicationTitle": "Epidemiology and infection", "publisher": "", "place": "England", "date": "2015 Apr", "volume": "143", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "1073-1078", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Epidemiol Infect", "DOI": "10.1017/S0950268814001605", "citationKey": "", "url": "", "accessDate": "", "PMID": "25034354", "PMCID": "PMC9507112", "ISSN": "1469-4409 0950-2688", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adolescent" }, { "tag": "Adult" }, { "tag": "Age Distribution" }, { "tag": "Aged" }, { "tag": "Child" }, { "tag": "Child, Preschool" }, { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Incidence" }, { "tag": "Infant" }, { "tag": "Infant, Newborn" }, { "tag": "Japan/epidemiology" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Retrospective Studies" }, { "tag": "Sex Distribution" }, { "tag": "Time Factors" }, { "tag": "Young Adult" }, { "tag": "spatial modelling" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "TU5BC2B8", "version": 206428, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/TU5BC2B8", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/TU5BC2B8", "type": "text/html" } }, "meta": { "creatorSummary": "Cathala et al.", "parsedDate": "1986-02-22", "numChildren": 0 }, "data": { "key": "TU5BC2B8", "version": 206428, "itemType": "journalArticle", "title": "[Creutzfeldt-Jakob disease in France. Value of familial forms. Is there a gene controlling the length of the incubation period?].", "creators": [ { "creatorType": "author", "firstName": "F.", "lastName": "Cathala" }, { "creatorType": "author", "firstName": "P.", "lastName": "Brown" }, { "creatorType": "author", "firstName": "J.", "lastName": "Chatelain" }, { "creatorType": "author", "firstName": "P.", "lastName": "Castaigne" }, { "creatorType": "author", "firstName": "C.", "lastName": "Gajdusek" } ], "abstractNote": "An extensive search for patients who died of Creutzfeld-Jakob disease in France between 1968 and 1982 resulted in the discovery of 327 cases, 233 of which were histologically proven and 29 transmitted to animals; 17 patients belonged to 6 families. Further investigations among members of these 6 families yielded 21 additional cases, i.e. a total of 38 familial cases. Studies among sibships suggested an autosomal dominant pattern of transmission but did not exclude lateral contamination infancy. The patients' age at death was 10 to 15 years lower than that of the total of French cases and seemed to be a characteristic of each individual family. This suggests that, as in scrapie, a gene may control the length of the incubation period.", "publicationTitle": "Presse medicale (Paris, France : 1983)", "publisher": "", "place": "France", "date": "1986 Feb 22", "volume": "15", "issue": "8", "section": "", "partNumber": "", "partTitle": "", "pages": "379-382", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Presse Med", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "2938156", "PMCID": "", "ISSN": "0755-4982", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "fre", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Aged" }, { "tag": "Animals" }, { "tag": "Creutzfeldt-Jakob Syndrome/epidemiology/*genetics/transmission" }, { "tag": "Female" }, { "tag": "France" }, { "tag": "Genes" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Time Factors" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } }, { "key": "DUBQET2H", "version": 206427, "library": { "type": "user", "id": 6212901, "name": "Nick Petosky", "links": { "alternate": { "href": "https://www.zotero.org/foxsayswhat", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/users/6212901/items/DUBQET2H", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/foxsayswhat/items/DUBQET2H", "type": "text/html" } }, "meta": { "creatorSummary": "Mitrová", "parsedDate": "1991-09", "numChildren": 0 }, "data": { "key": "DUBQET2H", "version": 206427, "itemType": "journalArticle", "title": "Some new aspects of CJD epidemiology in Slovakia.", "creators": [ { "creatorType": "author", "firstName": "E.", "lastName": "Mitrová" } ], "abstractNote": "Descriptive epidemiological and genealogical data obtained by prospective and retrospective studies on CJD in Slovakia and in patients emigrating from CJD clusters were analysed. Observations contradictory to an exclusively genetic etiology of temporo-spatial accumulation of CJD are presented. Data indicating a genetically increased susceptibility to the disease and its coincidence with environmental risk in clustering patients are discussed.", "publicationTitle": "European journal of epidemiology", "publisher": "", "place": "Netherlands", "date": "1991 Sep", "volume": "7", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "439-449", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Eur J Epidemiol", "DOI": "10.1007/BF00143119", "citationKey": "", "url": "", "accessDate": "", "PMID": "1761100", "PMCID": "", "ISSN": "0393-2990", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Creutzfeldt-Jakob Syndrome/*epidemiology/genetics" }, { "tag": "Czechoslovakia/epidemiology" }, { "tag": "Disease Susceptibility" }, { "tag": "Female" }, { "tag": "Humans" }, { "tag": "Male" }, { "tag": "Middle Aged" }, { "tag": "Pedigree" }, { "tag": "Prospective Studies" }, { "tag": "Retrospective Studies" }, { "tag": "Risk Factors" } ], "collections": [ "344H8INJ" ], "relations": {}, "dateAdded": "2026-07-09T16:28:02Z", "dateModified": "2026-07-09T16:28:02Z" } } ]