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            "version": 1895,
            "itemType": "journalArticle",
            "title": "Is the natural anatomical evolution of type B intramural hematomas reliable to identify the patients at risk of aneurysmal progression?",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Sonia",
                    "lastName": "Bolomey"
                },
                {
                    "creatorType": "author",
                    "firstName": "Arnaud",
                    "lastName": "Blanchard"
                },
                {
                    "creatorType": "author",
                    "firstName": "Pierre-Antoine",
                    "lastName": "Barral"
                },
                {
                    "creatorType": "author",
                    "firstName": "Julien",
                    "lastName": "Mancini"
                },
                {
                    "creatorType": "author",
                    "firstName": "David",
                    "lastName": "Lagier"
                },
                {
                    "creatorType": "author",
                    "firstName": "Laurence",
                    "lastName": "Bal"
                },
                {
                    "creatorType": "author",
                    "firstName": "Mariangela",
                    "lastName": "De Masi"
                },
                {
                    "creatorType": "author",
                    "firstName": "Alexis",
                    "lastName": "Jacquier"
                },
                {
                    "creatorType": "author",
                    "firstName": "Philippe",
                    "lastName": "Piquet"
                },
                {
                    "creatorType": "author",
                    "firstName": "Marine",
                    "lastName": "Gaudry"
                }
            ],
            "abstractNote": "OBJECTIVES: The natural history of type B intramural hematomas is little-known. Aneurysmal progression or an aortic dissection occurs in 15 to 20% of the cases. The study of the natural anatomical evolution could help to identify the patients at risk of unfavorable evolution.\nMATERIALS AND METHODS: All the patients monitored for a type B intramural hematoma between 2009 and 2018 were included in this monocentric retrospective study. CTA centerline measurement of diameters was obtained in various points of aortic segmentation on D0 and at one month (M1). Aortic volumes (lumen, intramural hematoma, total volume) were calculated. The circulating volume was calculated using the volume rendering method. The volume of the intramural hematoma was measured using a manual section by section segmentation tool, and the total volume was obtained by summing up the two preceding volumes. Two groups of patients were compared: group 1 (favorable anatomical evolution) and group 2 (unfavorable anatomical evolution).\nRESULTS: Between January 2008 and August 2018, 25 patients were managed for a type B intramural hematoma in our center. After an average follow-up of 15.5 months (1-52) 13 patients (52%) presented a favorable evolution and 12 (48%) an unfavorable evolution. At M1 a significant increase of the luminal diameters (37 mm vs 32 mm; p < 0.01) and a significant reduction in the longitudinal extension (19 mm vs 26 mm; p<0.01) were observed. The maximum aortic diameter evolved significantly between J0 and M1 in the unfavorable evolution group (49 mm vs 44; p=0.038). Such a difference was not found in the favorable evolution group (37.4 vs 37.1; p=0.552). An overall significant reduction in the total aortic volume (166 cm3 vs 219 cm3; p<0.01), the circulating volume (124 cm3 vs 145 cm3; p=0,026) and the volume of the hematoma (42 cm3 vs 39 cm3; p<0.01) was observed. The circulating volume decreased significantly between D0 and M1 in the favorable evolution group (110 cm3 vs 135 cm3; p=0.05) whereas no difference was noted in the unfavorable group (142 cm3 vs 157 cm3; p=0.24).\nCONCLUSION: The progression of the maximum aortic diameter and of the circulating volume after one month of follow-up could be predictive factors of the poor long-term evolution of type B intramural hematomas.",
            "publicationTitle": "Annals of Vascular Surgery",
            "publisher": "",
            "place": "",
            "date": "Jan 02, 2020",
            "volume": "",
            "issue": "",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Ann Vasc Surg",
            "DOI": "10.1016/j.avsg.2019.11.048",
            "citationKey": "",
            "url": "",
            "accessDate": "",
            "PMID": "31904521",
            "PMCID": "",
            "ISSN": "1615-5947",
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            "language": "eng",
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            "creatorSummary": "Bonello et al.",
            "parsedDate": "2019",
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        "data": {
            "key": "FR94W6PJ",
            "version": 1895,
            "itemType": "journalArticle",
            "title": "Etiology and Prognosis of Cardiogenic Shock in a Secondary Center without Surgical Back-Up",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Laurent",
                    "lastName": "Bonello"
                },
                {
                    "creatorType": "author",
                    "firstName": "Marc",
                    "lastName": "Laine"
                },
                {
                    "creatorType": "author",
                    "firstName": "Etienne",
                    "lastName": "Puymirat"
                },
                {
                    "creatorType": "author",
                    "firstName": "Victoria",
                    "lastName": "Ceccaldi"
                },
                {
                    "creatorType": "author",
                    "firstName": "Mélanie",
                    "lastName": "Gaubert"
                },
                {
                    "creatorType": "author",
                    "firstName": "Franck",
                    "lastName": "Paganelli"
                },
                {
                    "creatorType": "author",
                    "firstName": "Pr Franck",
                    "lastName": "Thuny"
                },
                {
                    "creatorType": "author",
                    "firstName": "Thibaut",
                    "lastName": "Dabry"
                },
                {
                    "creatorType": "author",
                    "firstName": "Guillaume",
                    "lastName": "Schurtz"
                },
                {
                    "creatorType": "author",
                    "firstName": "Clement",
                    "lastName": "Delmas"
                },
                {
                    "creatorType": "author",
                    "firstName": "Julien",
                    "lastName": "Mancini"
                },
                {
                    "creatorType": "author",
                    "firstName": "Gilles",
                    "lastName": "Lemesle"
                }
            ],
            "abstractNote": "Background: Cardiogenic shock (CS) remains a major challenge in contemporary cardiology. Data regarding CS etiologies and their prognosis are limited and mainly derived from tertiary referral centers.\nAims: To investigate the current etiologies of cardiogenic shock and their associated short- and long-term outcomes in a secondary center without surgical back-up.\nMethods: We performed an observational prospective monocenter study. All patients admitted for a first episode of CS related to left ventricular dysfunction were enrolled. The definition of CS was consistent with the European Society of Cardiology guidelines. Patients were followed for 6 months. Etiologies were analyzed, and survival rates derived from Kaplan-Meier estimates were compared with the log-rank test.\nResults: Between January 2015 and January 2016, 152 patients were included. The first most common cause of CS was acute decompensation of chronic heart failure (CHF). Acute coronary syndromes (ACS) were the second most common cause of CS (35.4%). At one month, the all-cause mortality rate was 39.5% and was similar between ACS and CHF (43% vs 35%, respectively; p=0.7). In a landmark analysis between 1 and 6 months, we observed a significantly higher mortality in patients with CHF than in patients with ACS (18% vs. 0%; p=0.01).\nConclusions: In the present registry, acute decompensation of chronic heart failure was the most common cause of CS, while ACS complicated by CS was the second most common cause. Of importance, acute decompensation of CHF was associated with a significantly worse outcome than ACS in the long term.",
            "publicationTitle": "Cardiology Research and Practice",
            "publisher": "",
            "place": "",
            "date": "2019",
            "volume": "2019",
            "issue": "",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "3869603",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Cardiol Res Pract",
            "DOI": "10.1155/2019/3869603",
            "citationKey": "",
            "url": "",
            "accessDate": "",
            "PMID": "31885900",
            "PMCID": "PMC6925788",
            "ISSN": "2090-8016",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "eng",
            "libraryCatalog": "PubMed",
            "callNumber": "",
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            "extra": "",
            "tags": [
                {
                    "tag": "Full Paper Publication"
                },
                {
                    "tag": "JM: Biostats / hors Cancer"
                }
            ],
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            "relations": {},
            "dateAdded": "2020-01-08T12:50:11Z",
            "dateModified": "2020-01-08T12:50:39Z"
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    {
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            "creatorSummary": "Serin et al.",
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            "title": "SFSPM 2018 — Congrès de la Société Française de Sénologie et de Pathologie Mammaire (Avignon, 7-9/11-2018)",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "D.",
                    "lastName": "Serin"
                },
                {
                    "creatorType": "author",
                    "firstName": "S.",
                    "lastName": "Adnot"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Allioux"
                },
                {
                    "creatorType": "author",
                    "firstName": "S.",
                    "lastName": "Alran"
                },
                {
                    "creatorType": "author",
                    "firstName": "B.",
                    "lastName": "Bazin"
                },
                {
                    "creatorType": "author",
                    "firstName": "M.-K.",
                    "lastName": "Bendiane"
                },
                {
                    "creatorType": "author",
                    "firstName": "E.",
                    "lastName": "Bo-Gallon"
                },
                {
                    "creatorType": "author",
                    "firstName": "D.",
                    "lastName": "Boinon"
                },
                {
                    "creatorType": "author",
                    "firstName": "A.-D.",
                    "lastName": "Bouhnik"
                },
                {
                    "creatorType": "author",
                    "firstName": "E.",
                    "lastName": "Bourstyn"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Charles"
                },
                {
                    "creatorType": "author",
                    "firstName": "A.",
                    "lastName": "Clément"
                },
                {
                    "creatorType": "author",
                    "firstName": "J.",
                    "lastName": "Coussirou"
                },
                {
                    "creatorType": "author",
                    "firstName": "B.",
                    "lastName": "Cutuli"
                },
                {
                    "creatorType": "author",
                    "firstName": "S.",
                    "lastName": "Dauchy"
                },
                {
                    "creatorType": "author",
                    "firstName": "P.",
                    "lastName": "Debourdeau"
                },
                {
                    "creatorType": "author",
                    "firstName": "L.",
                    "lastName": "Degos"
                },
                {
                    "creatorType": "author",
                    "firstName": "P.",
                    "lastName": "Duponchel"
                },
                {
                    "creatorType": "author",
                    "firstName": "T.",
                    "lastName": "Durand"
                },
                {
                    "creatorType": "author",
                    "firstName": "F.",
                    "lastName": "Eisinger"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Falandry"
                },
                {
                    "creatorType": "author",
                    "firstName": "B.",
                    "lastName": "Favier"
                },
                {
                    "creatorType": "author",
                    "firstName": "P. E.",
                    "lastName": "Heudel"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Ledig"
                },
                {
                    "creatorType": "author",
                    "firstName": "A.",
                    "lastName": "Lesur"
                },
                {
                    "creatorType": "author",
                    "firstName": "J.",
                    "lastName": "Mancini"
                },
                {
                    "creatorType": "author",
                    "firstName": "A.",
                    "lastName": "Monet"
                },
                {
                    "creatorType": "author",
                    "firstName": "J.",
                    "lastName": "Moretta"
                },
                {
                    "creatorType": "author",
                    "firstName": "J.",
                    "lastName": "Neveu"
                },
                {
                    "creatorType": "author",
                    "firstName": "G.",
                    "lastName": "Ninot"
                },
                {
                    "creatorType": "author",
                    "firstName": "M.",
                    "lastName": "Préau"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Ravot"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Rousset-Jablonski"
                },
                {
                    "creatorType": "author",
                    "firstName": "R.",
                    "lastName": "Touzani"
                },
                {
                    "creatorType": "author",
                    "firstName": "M.",
                    "lastName": "Valéro"
                },
                {
                    "creatorType": "author",
                    "firstName": "J.-J.",
                    "lastName": "Zambrowski"
                }
            ],
            "abstractNote": "Les 40es Journées de la SFSPM se sont tenues à Avignon du 7 au 9 novembre 2018. Le thème abordé—Cancer du sein : optimisation du parcours de soins — a réuni plus de 1 200 participants sous les voûtes du Palais des Papes. La fluidité de chaque segment du parcours a été analysée en termes de risques de rupture de continuité des soins tant au sein du segment lui-même qu’en amont et en aval. Dans un parcours par essence pluridisciplinaire et plurimétiers, la nécessité d’une réflexion globale et d’une coordination active réalisées par des professionnels formés a été rappelée à chaque session. Chacun des intervenants a esquissé de potentiels indicateurs de qualité tenant compte à la fois de son implication dans son segment d’intervention, mais tenant compte aussi d’une vision plus globale de ce que devrait être le parcours au travers de la maladie et des soins. La parole a été très largement partagée entre soignants et associations de malades, entre paramédicaux et acteurs en sciences humaines et sociales, entre responsables de la santé publique HAS, ARS, CNAM–CPAM 84 et représentants des différents modes d’hospitalisation publique/privée et ESPIC. La session grand public a été l’occasion d’échanges fructueux et instructifs sur la perception des difficultés comme des satisfactions rencontrées que nous ont fait partager les malades, leurs proches et les représentantes des associations. Au total, un congrès de réflexion partagé par de nombreux acteurs qui cherchent tous à améliorer le parcours de soins des malades atteintes de cancer du sein. La publication le 21 janvier par l’INCa de dix indicateurs de qualité du parcours de soins pour les malades atteints de cancer du sein est une étape importante qu’attendaient tous les participants d’Avignon — SFSPM 2018.",
            "publicationTitle": "Oncologie",
            "publisher": "",
            "place": "",
            "date": "2018/07/01",
            "volume": "20",
            "issue": "7-12",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "145-189",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Oncol.",
            "DOI": "10.3166/onco-2019-0040",
            "citationKey": "",
            "url": "https://onco.revuesonline.com/articles/lvonco/abs/2018/05/lvonco_2019_spronco001775/lvonco_2019_spronco001775.html",
            "accessDate": "2019-11-05T13:14:00Z",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1292-3818, 1765-2839",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "fr",
            "libraryCatalog": "onco.revuesonline.com",
            "callNumber": "",
            "rights": "© Lavoisier SAS 2019",
            "extra": "",
            "tags": [
                {
                    "tag": "Abstract Form Publication"
                },
                {
                    "tag": "JM: SESSTIM / Canbios"
                }
            ],
            "collections": [],
            "relations": {},
            "dateAdded": "2019-11-05T13:14:00Z",
            "dateModified": "2019-11-05T13:14:42Z"
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                    "lastName": "Nicollas"
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            "title": "Platelet reactivity inhibition following ticagrelor loading dose in patients undergoing percutaneous coronary intervention for acute coronary syndrome",
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                    "firstName": "Marc",
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                    "lastName": "Gouarne"
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                    "firstName": "Franck",
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                    "firstName": "Marie-Christine",
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                    "firstName": "Laurent",
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            "abstractNote": "BACKGROUND: Ticagrelor induces more potent platelet reactivity (PR) inhibition with reduced interindividual variability compared to clopidogrel. Although on-clopidogrel PR was shown to correlate with ischemia and bleeding events, no study has investigated the relationship between on ticagrelor PR and outcome.\nOBJECTIVES: We aimed to evaluate the relationship between on ticagrelor PR, assessed by the vasodilator-stimulated phosphoprotein index (VASP), and thrombotic and bleeding events in patients with acute coronary syndrome (ACS) treated by percutaneous coronary intervention (PCI).\nMETHODS: We performed a prospective, multicenter observational study on patients treated with PCI for ACS. The VASP index was used to assess PR after ticagrelor loading dose (LD). The primary endpoint was the link between major adverse cardiovascular events (MACE) and PR.\nRESULTS: Among the included 530 patients with ACS, 183 (34.5%) were admitted for ST elevation myocardial infarction. We observed high potency and limited interindividual variability after the ticagrelor LD (VASP 19.1 ± 16.6%). At 1 month, 21 (3.8%) MACE and 29 (5.5%) bleedings Academic Research Consortium ≥2 events were recorded. Neither MACE nor bleeding were associated with PR (p= 0.34 and p= 0.78 respectively). However, there was a strong association between PR and the occurrence of definite acute stent thrombosis (p= 0.03). PR was the only factor associated with acute definite stent thrombosis.\nCONCLUSION: In patients receiving a ticagrelor LD while undergoing PCI for ACS, PR using the VASP did not predict MACE or bleeding, but it was significantly associated with the occurrence of definite acute stent thrombosis. This article is protected by copyright. All rights reserved.",
            "publicationTitle": "Journal of thrombosis and haemostasis: JTH",
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            "title": "Do early luteal serum progesterone levels predict the reproductive outcomes in IVF with oral dydrogesterone for luteal phase support?",
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                    "lastName": "Netter"
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            "abstractNote": "OBJECTIVE: We sought to determine whether the early luteal serum progesterone (P4) level predicts the success of IVF treatment with oral dydrogesterone for luteal support.\nMETHOD: This retrospective monocentric cohort study included 242 women who underwent IVF treatment with fresh embryo transfer (ET) between July 2017 and June 2018. The population was unselected, and women were treated according to our unit's usual stimulation protocols. For the luteal phase support (LPS), all women were supplemented with a 10 mg three-times-daily dose of oral dydrogesterone beginning on the day of oocyte pick-up (OPU). Blood sampling was performed on the day of ET (Day 2-3 after OPU) to determine the early luteal serum progesterone level.\nRESULTS: ROC curve analysis allowed us to determine two thresholds for the prediction of live birth using the early P4 level. Women who had early luteal P4 levels greater than 252 nmol/l had a significantly higher live birth rate (27.1%) than women with early luteal P4 between 115 and 252 nmol/l (17.2%) and women with early luteal P4 below 115 nmol/l (6.0%; p = 0.011). After a multiple regression analysis, an early luteal P4 level greater than 252 nmol/l was still associated with a higher chance of a live birth than a P4 between 115 and 252 nmol/l (OR = 0.40 [0.18-0.91]; p = 0.028) or a P4 below 115 nmol/l (OR = 0.10 [0.01-0.52]; p = 0.006).\nCONCLUSIONS: Our study suggests a positive association between early P4 levels and reproductive outcomes in IVF using oral dydrogesterone for luteal support. The inconsistencies between our results and those of other studies suggest that extrapolation is impractical. Further larger prospective cohort studies should be conducted to determine reliable thresholds that could be used to personalize luteal phase support.",
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            "abstractNote": "PURPOSE: The prevalence of breast cancer is increasing in low- to middle-income countries such as Senegal. Our prospective study assessed the quality of life (QoL) of patients with breast cancer undergoing chemotherapy in Senegal.\nPATIENTS AND METHODS: Our study included women with breast cancer undergoing chemotherapy as initial treatment at the Center Aristide Le Dantec University Hospital in Dakar. Clinical, sociodemographic, and QoL data were collected and analyzed at three different times: baseline, 3 months, and 6 months after the start of systemic therapy. Health-related QoL was assessed using a Functional Assessment of Cancer Therapies-Breast (FACT-B) questionnaire after translation into the Wolof language. Linear mixed-effects models were performed to assess the changes in QoL scores.\nRESULTS: Between July 2017 and February 2018, 120 patients were included in the study. Their median age was 45 years. Most patients (n = 105; 92%) had locally advanced disease (T3 to T4 stage) and lymph node involvement (n = 103; 88%), and half had metastatic disease. The FACT-B total scores significantly improved over time (β = 1.58; 95% CI, 0.50 to 2.67; P < .01). Nausea and vomiting were significantly associated with a decrease in FACT-B total scores (β = -16.89, 95% CI, -29.58 to -4.24, P = .012; and β = -13.44, 95% CI, -25.15 to -1.72, P = .028, respectively).\nCONCLUSION: Our study confirmed the feasibility of standardized QoL assessment in Senegalese patients with breast cancer. Our results indicated a potential improvement of QoL over the course of chemotherapy. Optimizing nausea and vomiting prevention may improve QoL.",
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            "PMID": "31322991",
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            "title": "Uptake of genetic counseling among adult children of BRCA1/2 mutation carriers in France",
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            "title": "Preoperative inferior mesenteric artery embolization is a cost-effective technique that may reduce the rate of aneurysm sac diameter enlargement and reintervention following EVAR",
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            "abstractNote": "PURPOSE: Type II endoleaks are the most common complications following endovascular repair of abdominal aortic aneurysms (EVAR). Some studies have shown the benefit of preventive inferior mesenteric artery (IMA) embolization, but its efficacy and cost-effectiveness continue to be controversial. The aim of this study was to evaluate the efficacy of this procedure on the increase in aneurysmal sac diameter during follow-up.\nMATERIALS AND METHODS: All consecutive patients who underwent the embolization of the IMA prior to EVAR in our center, between January 2014 and July 2016, were included. We retrospectively compared the diameter of the aortic aneurysm sac, the rate of endoleak and reinterventions, and the theoretical cost of management between these patients (group 2) and a historical cohort of patients treated for EVAR before January 2014 who did not undergo prior IMA embolization (group 1).\nRESULTS: Two hundred and twenty four patients were retrospectively analysed. After exclusion, we compared a group of 37 embolized patients with a control group of 46 patients. The rate of enlargement in the aneurysmal sac diameter was significantly higher in the control group at 2 years (27.9% vs 4.3%, p=0.025). The type II endoleak rate at 2 years was significantly higher in the control group (53.1% vs 18.2%, P=0.012) as was the aneurysm-related re-intervention rate (31.1% vs 8.1%, p=0.013). Multivariate analysis confirmed these results. At 2 years of follow-up, there was no difference in the overall cost of patient management between 2 groups.\nCONCLUSION: Preventive IMA embolization is an effective, reliable and cost-effective technique that seems to reduce the rate of the aneurysmal sac diameter enlargement, type II endoleak and reinterventions after EVAR.",
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            "title": "Role of diffusion-weighted imaging in the discrimination of purulent intrasinusal content: a retrospective study",
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                    "lastName": "Radulesco"
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            "abstractNote": "OBJECTIVES: The objective of this study was to analyze MRI with morphological (T1, T2) and diffusion sequences (DWI, b1000) in patients presenting non-aggressive patterns of sinus opacity and operated on by Functional Endoscopic Sinus Surgery (FESS).\nDESIGN: A retrospective study.\nSETTING: Diffusion imaging in paranasal sinus pathology remains little known. To date, no imaging system is capable of determining the purulent content of a non-enhanced sinus filling.\nPARTICIPANTS: We included consecutive patients having undergone FESS in whom MRI of the paranasal sinuses were performed. Subjects were allocated to Case (pus) or Control (no pus) groups depending on sinus content found intraoperatively. FESS was performed for bacterial acute rhinosinusitis, acute exacerbations of chronic rhinosinusitis, non-purulent sinusitis, naso-sinusal polyposis, antro-choanal polyp, isolated polyp, angiomatous polyp and eosinophilic fungal sinusitis. Tumors, mucoceles and fungus balls were excluded.\nMAIN OUTCOME MEASURES: We analyzed T1, T2, b1000 and MRI sequences and ADC map.\nRESULTS: On univariate analysis, intermediate signal in T2 and high signal in b1000 were associated with Cases (p<0.001) as were low ADC values (p<0.001). The difference in mean ADC values between Cases and Controls were statistically significant (respectively 0.518 vs 2.041 x10-3 mm2 /sec, p<0.01). On multivariate analysis, MRI with ADC<0.725 x10-3 mm2 /sec and b1000_SI>brain were significantly associated with the Case group. MRI with b1000_SI< brain and ADC>1.450x10-3 mm2 /sec were significantly associated with the Control group.\nCONCLUSIONS: Diffusion MRI offers extremely promising results regarding content characterization of infectious sinus diseases. This article is protected by copyright. All rights reserved.",
            "publicationTitle": "Clinical otolaryngology: official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery",
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