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            ],
            "abstractNote": "Several studies have demonstrated neurobehavioral impairment related to manganese (Mn) exposure in the workplace. Exposure to high doses of manganese is associated with irreversible neurodegenerative disorders resembling idiopathic Parkinson disease. Although there is a risk of Mn accumulation in the foetus during pregnancy, little information exists about developmental effects of environmental low-level exposure in human. For this reason, we conducted a prospective epidemiological study in 247 healthy pregnant women and their babies to determine the long-term effect of in utero Mn levels on child's psychomotor development. Concurrently, we examined the relationship between Mn tissue levels at delivery and foetal plasma monoamine metabolites. Of the newborns, 195 were examined at 9 months, 126 at 3 years and 100 at 6 years. At 9 months, the Brunet-L�zine scales were administered. The McCarthy scales of children's abilities were used at 3 and 6 years. After adjustment for potential confounding co-factors (child's gender, mother's educational level), negative relationships were observed between cord blood Mn levels and several psychomotor sub-scales at age of 3 years: \"attention\" (partial r=-0.33, P<0.001), \"non-verbal memory\" (partial r=-0.28, P<0.01), and \"hand skills\" (partial r=-0.22, P<0.05). No significant relationships were observed between Mn measures at birth and the general psychomotor indices, Brunet-L�zine developmental quotient (DQ) at 9 months or McCarthy general cognitive index (GCI) at 3 and 6 years. Maternal blood Mn levels were negatively associated with foetal plasma HVA and 5-HIAA concentrations (adjusted for labour duration, child's gender, and smoking during pregnancy), but the adjustment for monoamine levels at birth did not change the association between the Mn levels and the psychomotor scores. These results suggest that environmental Mn exposure in utero could affect early psychomotor development.",
            "publicationTitle": "NeuroToxicology",
            "publisher": "",
            "place": "",
            "date": "2003",
            "volume": "24",
            "issue": "4-5",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "667-674",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
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            "url": "http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W81-48TM0TX-C&_user=1072191&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000051289&_version=1&_urlVersion=0&_userid=1072191&md5=191162b419b3a802ee7efb8f2b3b3eec",
            "accessDate": "",
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            "shortTitle": "Manganese, Monoamine Metabolite Levels at Birth, and Child Psychomotor Development",
            "language": "",
            "libraryCatalog": "",
            "callNumber": "",
            "rights": "",
            "extra": "",
            "tags": [
                {
                    "tag": "Dopamine"
                },
                {
                    "tag": "Manganese"
                },
                {
                    "tag": "Psychomotor development"
                },
                {
                    "tag": "Serotonin"
                }
            ],
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            "creatorSummary": "Stamler et al.",
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            "title": "Relationship between platelet monoamine oxidase-B (MAO-B) activity and mercury exposure in fish consumers from the Lake St. Pierre region of Que., Canada",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "C. J.",
                    "lastName": "Stamler"
                },
                {
                    "creatorType": "author",
                    "firstName": "N.",
                    "lastName": "Abdelouahab"
                },
                {
                    "creatorType": "author",
                    "firstName": "C.",
                    "lastName": "Vanier"
                },
                {
                    "creatorType": "author",
                    "firstName": "D.",
                    "lastName": "Mergler"
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                {
                    "creatorType": "author",
                    "firstName": "H. M.",
                    "lastName": "Chan"
                }
            ],
            "abstractNote": "Mercury (Hg) is a widespread neurotoxic compound that bio-accumulates in fish and marine mammals. Monoamine oxidase (MAO; EC 1.4.3.4) regulates biogenic amine concentration in the brain and peripheral tissue and has been shown to be a molecular target of Hg compounds in animal models. Blood platelet monoamine oxidase-B (MAO-B) activity may reflect MAO function in the central nervous tissue. Therefore, the objective of this study was to evaluate the relationship between platelet MAO-B and Hg exposure in fish-eating adults (n=127) living along the St. Lawrence River (Lake St. Pierre, Que., Canada). Hg concentrations were determined in blood and hair samples. A significant negative association was observed between platelet MAO-B activity and blood-Hg (r=-0.193, p=0.029) but not with hair-Hg levels (r=-0.125, p=0.169). Multiple linear regression analysis demonstrated that blood-Hg (beta=-4.6, p=0.011) and heavy smoking (beta=-8.5, p=0.001) were associated with reduced platelet MAO activity in the total population. In addition, this reduction in MAO-B activity appeared to be associated with blood-Hg concentrations above 3.4 microg/L (75th percentile). Possible gender related differences were also observed and are discussed. Our results suggest that MAO-B activity in blood platelets may be a useful tool to assess biochemical effects of Hg exposure in human populations. These changes in platelet MAO-B may reflect enzymatic changes in nervous tissue and should be further investigated as a surrogate marker of neurotoxicity.",
            "publicationTitle": "NeuroToxicology",
            "publisher": "",
            "place": "",
            "date": "2006 May",
            "volume": "27",
            "issue": "3",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "429-36",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "",
            "DOI": "10.1016/j.neuro.2005.12.005",
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            "PMID": "",
            "PMCID": "",
            "ISSN": "0161-813X (Print)",
            "archive": "",
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            "shortTitle": "Relationship between platelet monoamine oxidase-B (MAO-B) activity and mercury exposure in fish consumers from the Lake St. Pierre region of Que., Canada",
            "language": "eng",
            "libraryCatalog": "",
            "callNumber": "",
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            "tags": [
                {
                    "tag": "Mercure, Contamination des aliments, Plaquettes sanguines, Monoamine oxidase, Genre"
                },
                {
                    "tag": "Mercure, Food contamination, Blood platelets, Monoamine oxidase, Gender"
                }
            ],
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            "title": "Expanding the practice of ecosystem health",
            "creators": [
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                    "firstName": "David J.",
                    "lastName": "Rapport"
                },
                {
                    "creatorType": "author",
                    "firstName": "Donna",
                    "lastName": "Mergler"
                }
            ],
            "abstractNote": "Le concept de la Santé écosystémique est né de la fusion de l’écologie, de la médecine et de la santé. Au cours des dernières décennies et suite à l’établissement d’une Société internationale pour la santé écosystémique, certains ont commencé à questionner la façon dont la santé humaine a été étudiée à la lumière de changements environnementaux complexes. Le Centre de recherches pour le développement international (CRDI) a proposé le concept d’approches écosystémiques de la santé humaine en étudiant comment les conditions sociales, culturelles, politiques et économiques dans les pays les plus pauvres influent sur l’environnement et la santé humaine. En mai 2003, le Forum international sur les approches écosystémiques de la santé humaine a offert aux adeptes l’occasion d’étudier comment la communauté de pratique en matière de santé écosystémique aborde les questions de santé humaine. Des déséquilibres dans les écosystèmes provoquent des situations qui accroissent la vulnérabilité des êtres humains à la maladie. De plus, nous commençons à peine à comprendre les problèmes de santé propres aux centres urbains surpeuplés et sévèrement pollués. L’impact de ces problèmes est amplifié par des conditions sociales et économiques défavorables. Ces problèmes relèvent de la dégradation des écosystèmes, ce qui suggère que la stratégie pour assurer la santé des populations repose sur la restauration des écosystèmes ou l’établissement de conditions qui réduisent leur vulnérabilité. Par conséquent, des approches pratiques de la santé humaine axées sur la nature des écosystèmes dans lesquels les êtres vivent, de même que sur les forces sociales et politiques qui les affectent, ont pris forme. Ce supplément d’ Ecohealth présente des exemples touchants du travail accompli dans le domaine des approches écosystémiques de la santé humaine. Les études de cas permettent d’espérer une amélioration mais indiquent que pour y parvenir, il faudra modifier de façon radicale les valeurs humaines et créer une science intégrée novatrice. Ces projets ne sont qu’un premier pas.",
            "publicationTitle": "EcoHealth",
            "publisher": "",
            "place": "",
            "date": "2004",
            "volume": "1",
            "issue": "Supplément 2",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "4-7",
            "series": "",
            "seriesTitle": "",
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            "url": "http://www.ecohealth.net/pdf/journal_pdf/Vol_1/Vol1_Supp2/EcoHealth_Editorial_1_S2.pdf",
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            "shortTitle": "Expanding the practice of ecosystem health",
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            "tags": [
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                    "tag": "Human health, Ecosystem health, Vulnerability"
                },
                {
                    "tag": "Santé humaine, Santé des écosystèmes, Vulnérabilité"
                }
            ],
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            "title": "La santé des travailleuses : la science est-elle aveugle?",
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                    "firstName": "Karen",
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            "abstractNote": "Ce livre est le fruit des recherches que Karen Messing poursuit depuis plus de vingt ans dans le domaine de la santé au travail. Sa réflexion porte plus particulièrement sur les résistances de la culture scientifique à saisir les aspects «invisibles» du travail dans le secteur des services, souvent effectué par des femmes. En examinant les conditions de travail des caissières, secrétaires, serveuses, infirmières, travailleuses d'usine, téléphonistes, préposées à l'entretien, Karen Messing met en question la division sexuelle du monde du travail et les préjugés qui freinent le débat sur la santé des travailleuses.\n\n« C'est à la lecture d'un texte étayé de réflexions critiques, illustré de nombreux exemples concrets, de témoignages des premières concernées et de données statistiques et ponctué d'anecdotes personnelles que nous invite Messing. Au terme de cette lecture qui instruit et fait refléchir tout à la fois, on en sait davantage sur les conditions de travail des femmes, sur leurs effets sur la santé de ces dernières et un peu plus sur les pourquoi des lacunes qu'affichent les connaissances dans le domaine. Face au tableau brossé par l'auteure, qui oserait encore prétendre que la santé des femmes au travail n'est pas une question prioritaire. » - Maria de Koninck (préface)\n\n« Le livre de Karen Messing est un des plus importants ouvrages parus dans le domaine de la santé et sécurité au travail au cours de la dernière moitié du XXe siècle. » - Claire Williams, Work, Employment and Society.",
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            "date": "2000",
            "publisher": "Éditions remue-ménage et Octarès",
            "place": "Montréal et Toulouse",
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            "url": "http://www.octares.com/boutique_fiche.asp?IdProd=58 http://www.editions-remuemenage.qc.ca/consulter.php?titre=137",
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                    "tag": "Femmes, Santé au travail, Division sexuelle au travail, Culture scientifique"
                },
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                    "tag": "Women, Occupational health, Gender division at work, Scientific culture"
                }
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            "itemType": "journalArticle",
            "title": "Be the fairest of them all: Challenges and recommendations for the treatment of gender in occupational health research",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Karen",
                    "lastName": "Messing"
                },
                {
                    "creatorType": "author",
                    "firstName": "Laura",
                    "lastName": "Punnett"
                },
                {
                    "creatorType": "author",
                    "firstName": "Meg",
                    "lastName": "Bond"
                },
                {
                    "creatorType": "author",
                    "firstName": "Kristina",
                    "lastName": "Alexanderson"
                },
                {
                    "creatorType": "author",
                    "firstName": "Jean",
                    "lastName": "Pyle"
                },
                {
                    "creatorType": "author",
                    "firstName": "Shelia",
                    "lastName": "Zahm"
                },
                {
                    "creatorType": "author",
                    "firstName": "David",
                    "lastName": "Wegman"
                },
                {
                    "creatorType": "author",
                    "firstName": "Susan R.",
                    "lastName": "Stock"
                },
                {
                    "creatorType": "author",
                    "firstName": "Sylvie de",
                    "lastName": "Grosbois"
                }
            ],
            "abstractNote": "BACKGROUND: Both women's and men's occupational health problems merit scientific attention. Researchers need to consider the effect of gender on how occupational health issues are experienced, expressed, defined, and addressed. More serious consideration of gender-related factors will help identify risk factors for both women and men. METHODS: The authors, who come from a number of disciplines (ergonomics, epidemiology, public health, social medicine, community psychology, economics, sociology) pooled their critiques in order to arrive at the most common and significant problems faced by occupational health researchers who wish to consider gender appropriately. RESULTS: This paper describes some ways that gender can be and has been handled in studies of occupational health, as well as some of the consequences. The paper also suggests specific research practices that avoid errors. Obstacles to gender-sensitive practices are considered. CONCLUSIONS: Although gender-sensitive practices may be difficult to operationalize in some cases, they enrich the scientific quality of research and should lead to better data and ultimately to well-targeted prevention programs.",
            "publicationTitle": "American Journal of Industrial Medicine",
            "publisher": "",
            "place": "",
            "date": "2003",
            "volume": "43",
            "issue": "6",
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            "pages": "618-629",
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            "tags": [
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                    "tag": "Gender, Sex, Women, Men, Research methodology, Epidemiology, Ergonomics"
                },
                {
                    "tag": "Genre, Sexe, Femme, Homme, Méthode de recherche, Épidémiologie, Ergonomie"
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            "itemType": "journalArticle",
            "title": "Desegregation and occupational health: how male and female hospital attendants collaborate on work tasks requiring physical effort",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Karen",
                    "lastName": "Messing"
                },
                {
                    "creatorType": "author",
                    "firstName": "Diane",
                    "lastName": "Elabidi"
                }
            ],
            "abstractNote": "Until recently, hospital attendants in Québec were assigned tasks on the basis of gender, but now few hospitals practise segregation explicitly. However, some attendants suggest that women attendants do not carry out their fair share of tasks involving physical effort, resulting in male attendants being exposed to increased risk of injury. To examine this assumption, the authors observed attendants carrying out 1,169 physical operations for a total of 61 hours. Surprisingly, women performed significantly more operations per hour than their male counterparts. After discussions with participants, a number of factors were proposed to account for the divergence between the assumption (that women did not share equally in physical tasks) and the authors' observation (that women carried out more tasks per hour than men). These factors include: retention of stronger women, stereotyping, and recourse to men for rare, extremely demanding operations. In conclusion, the authors suggest that the desegregation of jobs should be accompanied by both observation and discussion to identify problems and adapt work practices and environments.",
            "publicationTitle": "Policy and Practice in Health and Safety",
            "publisher": "",
            "place": "",
            "date": "2003",
            "volume": "1",
            "issue": "1",
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            "pages": "83-103",
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            "archive": "",
            "archiveLocation": "",
            "shortTitle": "Desegregation and occupational health: how male and female hospital attendants collaborate on work tasks requiring physical effort",
            "language": "",
            "libraryCatalog": "",
            "callNumber": "",
            "rights": "",
            "extra": "",
            "tags": [
                {
                    "tag": "Ergonomics, Teamwork, Male-female differences, Non-traditional jobs"
                },
                {
                    "tag": "Ergonomie, Travail en équipe, Différences mâle-femelle, Emploi non-traditionnel"
                }
            ],
            "collections": [],
            "relations": {
                "owl:sameAs": "http://zotero.org/groups/269067/items/JZ2I4VQA"
            },
            "dateAdded": "2016-04-08T15:44:25Z",
            "dateModified": "2016-04-08T15:44:25Z"
        }
    }
]