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            "creatorSummary": "Yang et al.",
            "parsedDate": "2007-07-13",
            "numChildren": 1
        },
        "data": {
            "key": "GMKVGTQT",
            "version": 2,
            "itemType": "journalArticle",
            "title": "Effects of different steeping methods and storage on caffeine, catechins and gallic acid in bag tea infusions",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Deng-Jye",
                    "lastName": "Yang"
                },
                {
                    "creatorType": "author",
                    "firstName": "Lucy Sun",
                    "lastName": "Hwang"
                },
                {
                    "creatorType": "author",
                    "firstName": "Jau-Tien",
                    "lastName": "Lin"
                }
            ],
            "abstractNote": "Bag teas, packed 3g of ground black, green, oolong, paochoung and pu-erh tea leaves (the particle size used was 1-2mm), were steeped in 150 mL of 70, 85 or 100 degrees C hot water to study the effects of the number of steeping (the same bag tea was steeped repeatedly eight times, 30s each time, as done in China for making ceremonial tea) and varied steeping durations (0.5-4 min) on caffeine, catechins and gallic acid in tea infusions. The changes in tea infusions during storage at 4 or 25 degrees C for 0-48 h and the variations in these compounds of bag tea infused with 150 mL of 4 or 25 degrees C cold water for 0.5-16 h were also investigated. A HPLC method with a C18 column and a step gradient solvent system consisting of acetonitrile and 0.9% acetic acid in deionized water was used for analysis. Results for all kinds of tea samples showed that the second tea infusion contained the highest contents of caffeine, catechins and gallic acid when bag teas were steeped in 70 degrees C water. It was different from that steeped at 85 and 100 degrees C, the highest contents existed in the first infusion. These compounds decreased gradually in later infusions. Higher amounts of caffeine, catechins and gallic acid could be released from bag teas as hotter water was used. As steeping duration prolonged, these ingredients increased progressively, however, their levels were lower than that cumulated from the infusions with the identical bag tea prepared recurrently at the same temperature and time points. (-)-Gallocatechin gallate and (+)-catechin existed in these tea infusions rarely and could not be detected until a certain amount of them infusing. Except gallic acid that showed a significant increase and caffeine that exhibited no significant change, all kinds of catechins decreased appreciably after tea infusions were stored at 25 degrees C for 36 h; nevertheless, all of them showed no evident changes at 4 degrees C storage. The caffeine, catechins and gallic acid in tea infused with cold water also increased with increasing duration. Their contents in 25 degrees C steeped tea were higher than that made at 4 degrees C; moreover, their infusion rates from bag teas to cold water were markedly lower than that steeped in hot water. Infusing efficiencies of non-gallated catechins were higher than gallated catechins under cold water steeping.",
            "publicationTitle": "Journal of chromatography. A",
            "publisher": "",
            "place": "",
            "date": "Jul 13, 2007",
            "volume": "1156",
            "issue": "1-2",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "312-320",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "J Chromatogr A",
            "DOI": "10.1016/j.chroma.2006.11.088",
            "citationKey": "",
            "url": "http://www.ncbi.nlm.nih.gov/pubmed/17161409",
            "accessDate": "",
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            "ISSN": "0021-9673",
            "archive": "",
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            "shortTitle": "",
            "language": "",
            "libraryCatalog": "NCBI PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 17161409",
            "tags": [
                {
                    "tag": "Caffeine",
                    "type": 1
                },
                {
                    "tag": "Catechin",
                    "type": 1
                },
                {
                    "tag": "Chromatography, High Pressure Liquid",
                    "type": 1
                },
                {
                    "tag": "Food Handling",
                    "type": 1
                },
                {
                    "tag": "Gallic Acid",
                    "type": 1
                },
                {
                    "tag": "Tea",
                    "type": 1
                },
                {
                    "tag": "Temperature",
                    "type": 1
                }
            ],
            "collections": [],
            "relations": {},
            "dateAdded": "2012-12-07T15:48:57Z",
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            "creatorSummary": "Hursel et al.",
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            "key": "FH7GTK22",
            "version": 1,
            "itemType": "journalArticle",
            "title": "The effects of green tea on weight loss and weight maintenance: a meta-analysis",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "R",
                    "lastName": "Hursel"
                },
                {
                    "creatorType": "author",
                    "firstName": "W",
                    "lastName": "Viechtbauer"
                },
                {
                    "creatorType": "author",
                    "firstName": "M S",
                    "lastName": "Westerterp-Plantenga"
                }
            ],
            "abstractNote": "INTRODUCTION\n\nDifferent outcomes of the effect of green tea on weight loss (WL) and weight maintenance (WM) have been reported in studies with subjects differing in ethnicity and habitual caffeine intake.\n\n\nPURPOSE\n\nTo elucidate by meta-analysis whether green tea indeed has a function in body weight regulation.\n\n\nMETHODS\n\nEnglish-language studies about WL and WM after green tea supplementation were identified through PubMed and based on the references from retrieved articles. Out of the 49 studies initially identified, a total of 11 articles fitted the inclusion criteria and provided useful information for the meta-analysis. Effect sizes (mean weight change in treatment versus control group) were computed and aggregated based on a random-effects model. The influence of several moderators on the effect sizes was examined.\n\n\nRESULTS\n\nCatechins significantly decreased body weight and significantly maintained body weight after a period of WL (microcirc=-1.31 kg; P<0.001). Inhibition of this effect by high habitual caffeine intake (>300 mg per day) failed to reach significance (microcirc=-0.27 kg for high and microcirc=-1.60 kg for low habitual caffeine intake; P=0.09). Also, the seemingly smaller effect of catechins in Caucasian (microcirc=-0.82 kg) subjects compared with Asians (microcirc=-1.51 kg; P=0.37) did not reach significance. Interaction of ethnicity and caffeine intake was a significant moderator (P=0.04).\n\n\nCONCLUSIONS\n\nCatechins or an epigallocatechin gallate (EGCG)-caffeine mixture have a small positive effect on WL and WM. The results suggest that habitual caffeine intake and ethnicity may be moderators, as they may influence the effect of catechins.",
            "publicationTitle": "International journal of obesity (2005)",
            "publisher": "",
            "place": "",
            "date": "Sep 2009",
            "volume": "33",
            "issue": "9",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "956-961",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Int J Obes (Lond)",
            "DOI": "10.1038/ijo.2009.135",
            "citationKey": "",
            "url": "http://www.ncbi.nlm.nih.gov/pubmed/19597519",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1476-5497",
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            "shortTitle": "The effects of green tea on weight loss and weight maintenance",
            "language": "",
            "libraryCatalog": "NCBI PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 19597519",
            "tags": [
                {
                    "tag": "Caffeine",
                    "type": 1
                },
                {
                    "tag": "Catechin",
                    "type": 1
                },
                {
                    "tag": "Humans",
                    "type": 1
                },
                {
                    "tag": "Obesity",
                    "type": 1
                },
                {
                    "tag": "Satiation",
                    "type": 1
                },
                {
                    "tag": "Tea",
                    "type": 1
                },
                {
                    "tag": "Weight Loss",
                    "type": 1
                }
            ],
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            "relations": {},
            "dateAdded": "2012-12-07T15:52:17Z",
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            "creatorSummary": "Carlsen et al.",
            "parsedDate": "2010",
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            "version": 1,
            "itemType": "journalArticle",
            "title": "The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Monica H",
                    "lastName": "Carlsen"
                },
                {
                    "creatorType": "author",
                    "firstName": "Bente L",
                    "lastName": "Halvorsen"
                },
                {
                    "creatorType": "author",
                    "firstName": "Kari",
                    "lastName": "Holte"
                },
                {
                    "creatorType": "author",
                    "firstName": "Siv K",
                    "lastName": "Bøhn"
                },
                {
                    "creatorType": "author",
                    "firstName": "Steinar",
                    "lastName": "Dragland"
                },
                {
                    "creatorType": "author",
                    "firstName": "Laura",
                    "lastName": "Sampson"
                },
                {
                    "creatorType": "author",
                    "firstName": "Carol",
                    "lastName": "Willey"
                },
                {
                    "creatorType": "author",
                    "firstName": "Haruki",
                    "lastName": "Senoo"
                },
                {
                    "creatorType": "author",
                    "firstName": "Yuko",
                    "lastName": "Umezono"
                },
                {
                    "creatorType": "author",
                    "firstName": "Chiho",
                    "lastName": "Sanada"
                },
                {
                    "creatorType": "author",
                    "firstName": "Ingrid",
                    "lastName": "Barikmo"
                },
                {
                    "creatorType": "author",
                    "firstName": "Nega",
                    "lastName": "Berhe"
                },
                {
                    "creatorType": "author",
                    "firstName": "Walter C",
                    "lastName": "Willett"
                },
                {
                    "creatorType": "author",
                    "firstName": "Katherine M",
                    "lastName": "Phillips"
                },
                {
                    "creatorType": "author",
                    "firstName": "David R, Jr",
                    "lastName": "Jacobs"
                },
                {
                    "creatorType": "author",
                    "firstName": "Rune",
                    "lastName": "Blomhoff"
                }
            ],
            "abstractNote": "BACKGROUND\n\nA plant-based diet protects against chronic oxidative stress-related diseases. Dietary plants contain variable chemical families and amounts of antioxidants. It has been hypothesized that plant antioxidants may contribute to the beneficial health effects of dietary plants. Our objective was to develop a comprehensive food database consisting of the total antioxidant content of typical foods as well as other dietary items such as traditional medicine plants, herbs and spices and dietary supplements. This database is intended for use in a wide range of nutritional research, from in vitro and cell and animal studies, to clinical trials and nutritional epidemiological studies.\n\n\nMETHODS\n\nWe procured samples from countries worldwide and assayed the samples for their total antioxidant content using a modified version of the FRAP assay. Results and sample information (such as country of origin, product and/or brand name) were registered for each individual food sample and constitute the Antioxidant Food Table.\n\n\nRESULTS\n\nThe results demonstrate that there are several thousand-fold differences in antioxidant content of foods. Spices, herbs and supplements include the most antioxidant rich products in our study, some exceptionally high. Berries, fruits, nuts, chocolate, vegetables and products thereof constitute common foods and beverages with high antioxidant values.\n\n\nCONCLUSIONS\n\nThis database is to our best knowledge the most comprehensive Antioxidant Food Database published and it shows that plant-based foods introduce significantly more antioxidants into human diet than non-plant foods. Because of the large variations observed between otherwise comparable food samples the study emphasizes the importance of using a comprehensive database combined with a detailed system for food registration in clinical and epidemiological studies. The present antioxidant database is therefore an essential research tool to further elucidate the potential health effects of phytochemical antioxidants in diet.",
            "publicationTitle": "Nutrition journal",
            "publisher": "",
            "place": "",
            "date": "2010",
            "volume": "9",
            "issue": "",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "3",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Nutr J",
            "DOI": "10.1186/1475-2891-9-3",
            "citationKey": "",
            "url": "http://www.ncbi.nlm.nih.gov/pubmed/20096093",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1475-2891",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "",
            "libraryCatalog": "NCBI PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 20096093",
            "tags": [
                {
                    "tag": "Antioxidants",
                    "type": 1
                },
                {
                    "tag": "Beverages",
                    "type": 1
                },
                {
                    "tag": "Cacao",
                    "type": 1
                },
                {
                    "tag": "Cereals",
                    "type": 1
                },
                {
                    "tag": "Dairy Products",
                    "type": 1
                },
                {
                    "tag": "Dietary Fats",
                    "type": 1
                },
                {
                    "tag": "Dietary Fats, Unsaturated",
                    "type": 1
                },
                {
                    "tag": "Dietary Supplements",
                    "type": 1
                },
                {
                    "tag": "Eggs",
                    "type": 1
                },
                {
                    "tag": "Fabaceae",
                    "type": 1
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                    "tag": "Food",
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                    "tag": "Food Analysis",
                    "type": 1
                },
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                    "tag": "Fruit",
                    "type": 1
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                    "tag": "Infant Food",
                    "type": 1
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                    "tag": "Infant Formula",
                    "type": 1
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                    "type": 1
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                    "tag": "Nuts",
                    "type": 1
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            "title": "Dietary antioxidants and cardiovascular disease",
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                    "firstName": "Rune",
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            ],
            "abstractNote": "PURPOSE OF REVIEW\n\nOxidative damage is involved in cardiovascular diseases. Intervention with alpha-tocopherol, ascorbic acid and beta-carotene does not appear to reduce pathogenesis. The purpose of this review is to describe alternative antioxidant mechanisms that may be involved.\n\n\nRECENT FINDINGS\n\nAntioxidants with different chemical properties may recharge each other in an antioxidant network. The total antioxidant content of dietary plants may therefore be a useful tool for testing the \"antioxidant network\" hypothesis. Several berries, fruits, nuts, seeds, vegetables, drinks and spices have been found to be high in total antioxidants. Initial studies in animals and humans are supportive as to the beneficial effects of dietary plants rich in total antioxidants. Additionally, antioxidants and other plant compounds may also improve the endogenous antioxidant defence through induction of antioxidant and phase 2 enzymes. Dietary plants rich in such compounds include broccoli, Brussels sprouts, cabbage, kale, cauliflower, carrots, onions, tomatoes, spinach and garlic.\n\n\nSUMMARY\n\nAlthough initial studies have indicated that antioxidants may reduce oxidative stress, human intervention studies do not support a beneficial effect of antioxidant supplements. Further research is needed to clarify whether other plant antioxidants, plants rich in a combination of antioxidants, or plant compounds that induce the endogenous antioxidant defence can reduce pathogenesis of cardiovascular disease and other oxidative stress-related diseases.",
            "publicationTitle": "Current opinion in lipidology",
            "publisher": "",
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            "date": "Feb 2005",
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            "pages": "47-54",
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                    "creatorType": "author",
                    "firstName": "Siv Fagertun",
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            "title": "The activity of gastric ghrelin positive cells in obese patients treated surgically",
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                    "creatorType": "author",
                    "firstName": "Jacek",
                    "lastName": "Dadan"
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                    "firstName": "Hady Razak",
                    "lastName": "Hady"
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                    "firstName": "Robert Lukasz",
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                    "firstName": "Paweł",
                    "lastName": "Iwacewicz"
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                    "firstName": "Artur",
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            "abstractNote": "Ghrelin is a 28 amino acid peptide hormone regulating food intake and stimulating releasement of growth hormone. It is produced in a distinct endocrine call known as X/A - like cells. The most abundant source of this very important factor in energy homeostasis is gastric fundus. Regulatory mechanisms of ghrelin synthesis and secretion in physiological and pathological states are not discovered completely. The aim of our study was evaluation of the activity of gastric X/A-like cells in obese patients before and after the most popular surgical bariatric procedures - Roux - Y Gastric Bypass (RYGB) and Laparoscopic Adjustable Gastric Banding (LAGB). Obese patients in number 18 took part in the study. LAGB was performed in 7 patients and RYGB in 11 patients. Peripheral blood was taken from each patient before operation and first day, seventh day, one month and three months after surgery. Ghrelin level was determined by RIA technique. The specimen of stomach was taken from circular stapler after gastrojejunostomy during RYGB and immunohistochemical study of gastric mucosa, using the EnVision method and specific monoclonal antybodies against ghrelin was performed. The intensity of ghrelin-immunoreactivity in X/A-like cells was analyzed using Olympus Cell D image analysis system. Efficiency of bariatric procedures was estimated by EWL- excess weight loss. We observed very strong immunohistochemical reactions of gastric X/A-like cells, accompanied by lower ghrelin plasma concentration, in comparison to the control group. LAGB procedure induced increase of ghrelin plasma level while RYGB procedure induced decrease of this hormone. The main finding of the present study is the hypoactivity of gastric X/A-like cells in obese patients in comparison to the control group.",
            "publicationTitle": "Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society",
            "publisher": "",
            "place": "",
            "date": "2009",
            "volume": "47",
            "issue": "2",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "307-313",
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            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Folia Histochem. Cytobiol.",
            "DOI": "10.2478/v10042-009-0033-z",
            "citationKey": "",
            "url": "http://www.ncbi.nlm.nih.gov/pubmed/19995718",
            "accessDate": "2012-06-14T19:52:36Z",
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                    "tag": "Adult",
                    "type": 1
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                {
                    "tag": "Female",
                    "type": 1
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                {
                    "tag": "Follow-Up Studies",
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                },
                {
                    "tag": "Gastric Bypass",
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                {
                    "tag": "Gastric Mucosa",
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                },
                {
                    "tag": "Ghrelin",
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                {
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                {
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                {
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                    "firstName": "Erick Prado",
                    "lastName": "de Oliveira"
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                    "creatorType": "author",
                    "firstName": "Roberto Carlos",
                    "lastName": "Burini"
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            "abstractNote": "ABSTRACT: High plasma uric acid (UA) is a precipitating factor for gout and renal calculi as well as a strong risk factor for Metabolic Syndrome and cardiovascular disease. The main causes for higher plasma UA are either lower excretion, higher synthesis or both. Higher waist circumference and the BMI are associated with higher insulin resistance and leptin production, and both reduce uric acid excretion. The synthesis of fatty acids (tryglicerides) in the liver is associated with the de novo synthesis of purine, accelerating UA production. The role played by diet on hyperuricemia has not yet been fully clarified, but high intake of fructose-rich industrialized food and high alcohol intake (particularly beer) seem to influence uricemia. It is not known whether UA would be a causal factor or an antioxidant protective response. Most authors do not consider the UA as a risk factor, but presenting antioxidant function. UA contributes to > 50% of the antioxidant capacity of the blood. There is still no consensus if UA is a protective or a risk factor, however, it seems that acute elevation is a protective factor, whereas chronic elevation a risk for disease.",
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            "title": "Encuesta-Nacional-de-Consumo-Alimentario-2010-2011.pdf (application/pdf Objeto)",
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