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            "title": "Generalized Anxiety Disorder",
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            "abstractNote": "What is Generalized Anxiety Disorder (GAD)?",
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            "itemType": "journalArticle",
            "title": "Prevalence, characteristics and comorbidities of anxiety disorders in France: Results from the \"Mental Health in General Population\" Survey (MHGP)",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "E.",
                    "lastName": "Leray"
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                {
                    "creatorType": "author",
                    "firstName": "A.",
                    "lastName": "Camara"
                },
                {
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                    "firstName": "D.",
                    "lastName": "Drapier"
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                {
                    "creatorType": "author",
                    "firstName": "F.",
                    "lastName": "Riou"
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                {
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                    "firstName": "N.",
                    "lastName": "Bougeant"
                },
                {
                    "creatorType": "author",
                    "firstName": "A.",
                    "lastName": "Pelissolo"
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                {
                    "creatorType": "author",
                    "firstName": "K. R.",
                    "lastName": "Lloyd"
                },
                {
                    "creatorType": "author",
                    "firstName": "V.",
                    "lastName": "Bellamy"
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                    "firstName": "J. L.",
                    "lastName": "Roelandt"
                },
                {
                    "creatorType": "author",
                    "firstName": "B.",
                    "lastName": "Millet"
                }
            ],
            "abstractNote": "Purpose Only a few European countries have carried out large, community-based, national surveys about psychiatric morbidity. Here is presented the first national French survey, aiming to estimate the prevalence of anxiety disorders and associated comorbidities according to sociodemographic characteristics. Materials and methods The Mental Health in General Population (MHGP) database is derived from a representative national survey of the French adult population ( n = 36,105), conducted between 1999 and 2003. Data collection was done using an anonymous face-to-face interview. The presence of anxiety disorders (generalized anxiety disorder, panic disorder, agoraphobia, social phobia and post-traumatic stress disorder) was assessed using the Mini International Neuropsychiatric Interview. Results The overall prevalence of anxiety disorders was estimated to be 21.6%, generalized anxiety disorder being the most prevalent one (12.8%). Women, young people, and people earning low income were identified as the more at risk. Major depressive episode, alcohol abuse and drug addiction frequently co-occur with anxiety disorders (28.3, 4.4 and 2.8% respectively). Conclusion The MHGP study showed that anxiety disorders are highly prevalent in France with a high frequency of comorbidities. Our results highlight the need for considering anxiety disorders as a public health priority in France as well as in other European countries.",
            "publicationTitle": "European Psychiatry",
            "publisher": "",
            "place": "",
            "date": "2011",
            "volume": "26",
            "issue": "6",
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            "partTitle": "",
            "pages": "339–345",
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            "DOI": "10.1016/j.eurpsy.2009.12.001",
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            "ISSN": "0924-9338",
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            "shortTitle": "Prevalence, characteristics and comorbidities of anxiety disorders in France",
            "language": "eng",
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            "callNumber": "",
            "rights": "",
            "extra": "",
            "tags": [
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                    "tag": "Anxiety Disorders",
                    "type": 1
                },
                {
                    "tag": "Epidemiology",
                    "type": 1
                }
            ],
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            "title": "The effects of co-morbidity on the onset and persistence of generalized anxiety disorder in the ICPE surveys",
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                    "firstName": "R. c",
                    "lastName": "Kessler"
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                    "lastName": "Andrade"
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            ],
            "abstractNote": "Although it is well known that generalized anxiety disorder (GAD) is highly co-morbid with other mental disorders, little is known about the extent to which earlier disorders predict the subsequent first onset and persistence of GAD. These associations are examined in the current report using data from four community surveys in the World Health Organization (WHO) International Consortium in Psychiatric Epidemiology (ICPE). The surveys come from Brazil, Canada, the Netherlands and the United States. The Composite International Diagnostic Interview (CIDI) was used to assess DSM-III-R anxiety, mood and substance use disorders in these surveys. Discrete-time survival analysis was used to examine the associations of retrospectively reported earlier disorders with first onset of GAD. Logistic regression analysis was used to examine the associations of the disorders with persistence of GAD. Six disorders predict first onset of GAD in all four surveys: agoraphobia, panic disorder, simple phobia, dysthymia, major depression and mania. With the exception of simple phobia, only respondents with active disorders have elevated risk of GAD. In the case of simple phobia, in comparison, respondents with a history of remitted disorder also have consistently elevated risk of GAD. Simple phobia is also the only disorder that predicts the persistence of GAD. The causal processes linking temporally primary disorders to onset of GAD are likely to be state-dependent. History of simple phobia might be a GAD risk marker. Further research is needed to explore the mechanisms involved in the relationship between simple phobia and subsequent GAD.",
            "publicationTitle": "Psychological Medicine",
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            "date": "2002",
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            "pages": "1213–1225",
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                    "firstName": "Sarah A.",
                    "lastName": "Hayes-Skelton"
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                    "firstName": "Susan M.",
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                    "lastName": "Dugas"
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            "abstractNote": "This study presents a preliminary test of a conceptual model of Generalized Anxiety Disorder (GAD) which is theoretically driven and has clear clinical implications. The model's main features are intolerance of uncertainty, beliefs about worry, poor problem orientation and cognitive avoidance. Subjects were 24 GAD patients and 20 non clinical control subjects. The results show that all main components of the model were highly related to the discriminant function and that intolerance of uncertainty was pivotal in distinguishing GAD patients from non clinical subjects. Further, the discriminant function derived from these four process variables was very effective for classifying GAD patients and non clinical subjects into their respective groups. Overall, 82% of subjects were correctly classified as 18 of 24 subjects in the GAD group and 18 of 20 subjects in the non clinical group were properly identified. The results are discussed in terms of the proposed model of GAD and its clinical implications.",
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