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Indeed, vaccination and cross immunity period are seen to decrease the frequency and magnitude of outbreaks but in a differentiated manner with specific effects depending upon the interaction vaccine and strain type.", "publicationTitle": "Mathematical Biosciences", "publisher": "", "place": "", "date": "", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Mathematical Biosciences", "DOI": "10.1016/j.mbs.2016.10.001", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0025556416302401", "accessDate": "2016-10-25T13:06:45Z", "PMID": "", "PMCID": "", "ISSN": "0025-5564", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "00000", "tags": [ { "tag": "Dengue", "type": 1 }, { "tag": "Serotypes", "type": 1 }, { "tag": "Vaccine effects", "type": 1 } ], "collections": [ "XGQM5VJK" ], "relations": {}, "dateAdded": "2016-10-25T13:06:45Z", "dateModified": "2017-01-01T21:10:45Z" } }, { "key": "EHBW5UNN", "version": 60, "library": { "type": "group", "id": 679106, "name": "Dengue Vaccine", "links": { "alternate": { "href": "https://www.zotero.org/groups/dengue_vaccine", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/679106/items/EHBW5UNN", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dengue_vaccine/items/EHBW5UNN", "type": "text/html" } }, "meta": { "createdByUser": { "id": 970601, "username": "joycefigueiro", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/joycefigueiro", "type": "text/html" } } }, "lastModifiedByUser": { "id": 27767, "username": "fccoelho", "name": "Flávio Codeço Coelho", "links": { "alternate": { "href": "https://www.zotero.org/fccoelho", "type": "text/html" } } }, "creatorSummary": "Villar et al.", "parsedDate": "2015-01-08", "numChildren": 2 }, "data": { "key": "EHBW5UNN", "version": 60, "itemType": "journalArticle", "title": "Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America", "creators": [ { "creatorType": "author", "firstName": "Luis", "lastName": "Villar" }, { "creatorType": "author", "firstName": "Gustavo Horacio", "lastName": "Dayan" }, { "creatorType": "author", "firstName": "José Luis", "lastName": "Arredondo-García" }, { "creatorType": "author", "firstName": "Doris Maribel", "lastName": "Rivera" }, { "creatorType": "author", "firstName": "Rivaldo", "lastName": "Cunha" }, { "creatorType": "author", "firstName": "Carmen", "lastName": "Deseda" }, { "creatorType": "author", "firstName": "Humberto", "lastName": "Reynales" }, { "creatorType": "author", "firstName": "Maria Selma", "lastName": "Costa" }, { "creatorType": "author", "firstName": "Javier Osvaldo", "lastName": "Morales-Ramírez" }, { "creatorType": "author", "firstName": "Gabriel", "lastName": "Carrasquilla" }, { "creatorType": "author", "firstName": "Luis Carlos", "lastName": "Rey" }, { "creatorType": "author", "firstName": "Reynaldo", "lastName": "Dietze" }, { "creatorType": "author", "firstName": "Kleber", "lastName": "Luz" }, { "creatorType": "author", "firstName": "Enrique", "lastName": "Rivas" }, { "creatorType": "author", "firstName": "Maria Consuelo", "lastName": "Miranda Montoya" }, { "creatorType": "author", "firstName": "Margarita", "lastName": "Cortés Supelano" }, { "creatorType": "author", "firstName": "Betzana", "lastName": "Zambrano" }, { "creatorType": "author", "firstName": "Edith", "lastName": "Langevin" }, { "creatorType": "author", "firstName": "Mark", "lastName": "Boaz" }, { "creatorType": "author", "firstName": "Nadia", "lastName": "Tornieporth" }, { "creatorType": "author", "firstName": "Melanie", "lastName": "Saville" }, { "creatorType": "author", "firstName": "Fernando", "lastName": "Noriega" } ], "abstractNote": "Dengue is a mosquito-borne disease that is present in many parts of the world. From 2003 through 2013, the number of dengue cases that were reported to the Pan American Health Organization (PAHO) increased by a factor of five.1–3 The disease is caused by one of four closely related virus serotypes from the genus flavivirus. Mosquitoes that transmit the virus are present in tropical and subtropical regions worldwide and in some temperate areas of the United States, Europe, Africa, and the Middle East.4 Dengue is an increasing public health problem despite efforts to manage epidemics through vector control.5 Several . . .", "publicationTitle": "New England Journal of Medicine", "publisher": "", "place": "", "date": "Janeiro 8, 2015", "volume": "372", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "113-123", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1056/NEJMoa1411037", "citationKey": "", "url": "http://dx.doi.org/10.1056/NEJMoa1411037", "accessDate": "2016-10-18T19:07:38Z", "PMID": "25365753", "PMCID": "", "ISSN": "0028-4793", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "Taylor and Francis+NEJM", "callNumber": "", "rights": "", "extra": "00297", "tags": [], "collections": [ "XGQM5VJK" ], "relations": {}, "dateAdded": "2016-10-18T19:07:38Z", "dateModified": "2017-01-01T21:10:42Z" } }, { "key": "97Z53TA7", "version": 60, "library": { "type": "group", "id": 679106, "name": "Dengue Vaccine", "links": { "alternate": { "href": "https://www.zotero.org/groups/dengue_vaccine", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/679106/items/97Z53TA7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dengue_vaccine/items/97Z53TA7", "type": "text/html" } }, "meta": { "createdByUser": { "id": 970601, "username": "joycefigueiro", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/joycefigueiro", "type": "text/html" } } }, "lastModifiedByUser": { "id": 27767, "username": "fccoelho", "name": "Flávio Codeço Coelho", "links": { "alternate": { "href": "https://www.zotero.org/fccoelho", "type": "text/html" } } }, "creatorSummary": "Hadinegoro et al.", "parsedDate": "2015", "numChildren": 2 }, "data": { "key": "97Z53TA7", "version": 60, "itemType": "journalArticle", "title": "Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease", "creators": [ { "creatorType": "author", "firstName": "Sri Rezeki", "lastName": "Hadinegoro" }, { "creatorType": "author", "firstName": "Jose Luis", "lastName": "Arredondo-García" }, { "creatorType": "author", "firstName": "Maria Rosario", "lastName": "Capeding" }, { "creatorType": "author", "firstName": "Carmen", "lastName": "Deseda" }, { "creatorType": "author", "firstName": "Tawee", "lastName": "Chotpitayasunondh" }, { "creatorType": "author", "firstName": "Reynaldo", "lastName": "Dietze" }, { "creatorType": "author", "firstName": "H.I.", "lastName": "Hj Muhammad Ismail" }, { "creatorType": "author", "firstName": "Humberto", "lastName": "Reynales" }, { "creatorType": "author", "firstName": "Kriengsak", "lastName": "Limkittikul" }, { "creatorType": "author", "firstName": "Doris Maribel", "lastName": "Rivera-Medina" }, { "creatorType": "author", "firstName": "Huu Ngoc", "lastName": "Tran" }, { "creatorType": "author", "firstName": "Alain", "lastName": "Bouckenooghe" }, { "creatorType": "author", "firstName": "Danaya", "lastName": "Chansinghakul" }, { "creatorType": "author", "firstName": "Margarita", "lastName": "Cortés" }, { "creatorType": "author", "firstName": "Karen", "lastName": "Fanouillere" }, { "creatorType": "author", "firstName": "Remi", "lastName": "Forrat" }, { "creatorType": "author", "firstName": "Carina", "lastName": "Frago" }, { "creatorType": "author", "firstName": "Sophia", "lastName": "Gailhardou" }, { "creatorType": "author", "firstName": "Nicholas", "lastName": "Jackson" }, { "creatorType": "author", "firstName": "Fernando", "lastName": "Noriega" }, { "creatorType": "author", "firstName": "Eric", "lastName": "Plennevaux" }, { "creatorType": "author", "firstName": "T. Anh", "lastName": "Wartel" }, { "creatorType": "author", "firstName": "Betzana", "lastName": "Zambrano" }, { "creatorType": "author", "firstName": "Melanie", "lastName": "Saville" } ], "abstractNote": "Development of a vaccine to prevent dengue infection is an unmet global need. 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"links": { "alternate": { "href": "https://www.zotero.org/fccoelho", "type": "text/html" } } }, "creatorSummary": "Reich et al.", "parsedDate": "2013-09-06", "numChildren": 3 }, "data": { "key": "WFNMRMM9", "version": 60, "itemType": "journalArticle", "title": "Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity", "creators": [ { "creatorType": "author", "firstName": "Nicholas G.", "lastName": "Reich" }, { "creatorType": "author", "firstName": "Sourya", "lastName": "Shrestha" }, { "creatorType": "author", "firstName": "Aaron A.", "lastName": "King" }, { "creatorType": "author", "firstName": "Pejman", "lastName": "Rohani" }, { "creatorType": "author", "firstName": "Justin", "lastName": "Lessler" }, { "creatorType": "author", "firstName": "Siripen", "lastName": "Kalayanarooj" }, { "creatorType": "author", "firstName": "In-Kyu", "lastName": "Yoon" }, { "creatorType": "author", "firstName": "Robert V.", "lastName": "Gibbons" }, { "creatorType": "author", "firstName": "Donald S.", "lastName": "Burke" }, { "creatorType": "author", "firstName": "Derek A. T.", "lastName": "Cummings" } ], "abstractNote": "Dengue, a mosquito-borne virus of humans, infects over 50 million people annually. Infection with any of the four dengue serotypes induces protective immunity to that serotype, but does not confer long-term protection against infection by other serotypes. The immunological interactions between serotypes are of central importance in understanding epidemiological dynamics and anticipating the impact of dengue vaccines. We analysed a 38-year time series with 12 197 serotyped dengue infections from a hospital in Bangkok, Thailand. Using novel mechanistic models to represent different hypothesized immune interactions between serotypes, we found strong evidence that infection with dengue provides substantial short-term cross-protection against other serotypes (approx. 1–3 years). This is the first quantitative evidence that short-term cross-protection exists since human experimental infection studies performed in the 1950s. These findings will impact strategies for designing dengue vaccine studies, future multi-strain modelling efforts, and our understanding of evolutionary pressures in multi-strain disease systems.", "publicationTitle": "Journal of The Royal Society Interface", "publisher": "", "place": "", "date": "2013/09/06", "volume": "10", "issue": "86", "section": "", "partNumber": "", "partTitle": "", "pages": "20130414", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1098/rsif.2013.0414", "citationKey": "", "url": "http://rsif.royalsocietypublishing.org/content/10/86/20130414", "accessDate": "2016-10-07T01:27:01Z", "PMID": "23825116", "PMCID": "", "ISSN": "1742-5689, 1742-5662", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "en", "libraryCatalog": "rsif.royalsocietypublishing.org", "callNumber": "", "rights": ". © 2013 The Authors. 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