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                    "lastName": "Wesseling"
                },
                {
                    "creatorType": "author",
                    "firstName": "Tania",
                    "lastName": "Schink"
                },
                {
                    "creatorType": "author",
                    "firstName": "Klaus",
                    "lastName": "Jung"
                }
            ],
            "abstractNote": "Background: ROC analysis is widely accepted to assess and compare diagnostic validity of laboratory tests. Within the last few years, many new ROC programs have become available but have not been systematically evaluated. The aim of this study was to assess different ROC programs regarding their ease of use, mathematical correctness, final output, and their compatibility with other graphics programs. Methods: Eight available programs running under Windows (AccuROC, Analyse-It, CMDT, GraphROC, MedCalc, mROC, ROCKIT, and SPSS) were evaluated. ROC analyses of prostate-specific antigen and related values were performed from a dataset of 928 men with prostate cancer and benign prostatic hyperplasia and corresponding subsets. Criteria such as data input, data output, and correctness and completeness of results were used to evaluate the practicability of the programs. Results: Although the programs produced equivalent results (areas under the curves and their characteristics), we observed deficiencies concerning input of data, processing of the output data, and completeness of the results. Analyse-It, AccuROC, and MedCalc exhibited good performance, but each program had different shortcomings. Only GraphROC could compare curves at a certain sensitivity or specificity cutoff. Conclusions: Adequate ROC analysis and ROC plotting cannot be performed with a single program. Analyse-It, AccuROC, and MedCalc can be recommended with certain limitations. Further improvements of the programs are necessary.",
            "publicationTitle": "Clinical Chemistry",
            "publisher": "",
            "place": "",
            "date": "March 1, 2003",
            "volume": "49",
            "issue": "3",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "433-439",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "",
            "DOI": "10.1373/49.3.433",
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            "accessDate": "2010-08-19T14:02:44Z",
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            "language": "",
            "libraryCatalog": "HighWire",
            "callNumber": "",
            "rights": "",
            "extra": "",
            "tags": [
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                    "tag": "ROC Curve"
                }
            ],
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            "dateAdded": "2011-12-05T09:52:26Z",
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        }
    },
    {
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            "creatorSummary": "Hanley and McNeil",
            "parsedDate": "1983-09-01",
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        "data": {
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            "itemType": "journalArticle",
            "title": "A method of comparing the areas under receiver operating characteristic curves derived from the same cases",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "J. A.",
                    "lastName": "Hanley"
                },
                {
                    "creatorType": "author",
                    "firstName": "B. J.",
                    "lastName": "McNeil"
                }
            ],
            "abstractNote": "",
            "publicationTitle": "Radiology",
            "publisher": "",
            "place": "",
            "date": "Septembre 1, 1983",
            "volume": "148",
            "issue": "3",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "839-843",
            "series": "",
            "seriesTitle": "",
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            "citationKey": "",
            "url": "http://radiology.rsnajnls.org/cgi/content/abstract/148/3/839",
            "accessDate": "2008-12-03T12:43:08Z",
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            "language": "",
            "libraryCatalog": "HighWire",
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            "rights": "",
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            "tags": [
                {
                    "tag": "ROC Curve"
                },
                {
                    "tag": "ROC curve comparison"
                }
            ],
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    },
    {
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            "creatorSummary": "Hanley",
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            "version": 1,
            "itemType": "journalArticle",
            "title": "The robustness of the \"binormal\" assumptions used in fitting ROC curves",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "J A",
                    "lastName": "Hanley"
                }
            ],
            "abstractNote": "The binormal form is the most common model used to formally fit ROC curves to the data from signal detection studies that employ the \"rating\" method. The author lists a number of justifications that have been offered for this choice, ranging from theoretical considerations of probability laws and signal detection theory, to mathematical tractability and convenience, to empirical results showing that \"it fits!\" To these justifications is added another, namely that even if an alternative formulation based on another underlying form (e.g., power law) or model (e.g., binomial, Poisson, or gamma type distributions) were in fact correct, the binormal fit differs so little from the true form as to be of no practical consequence. Moreover, the small lack of fit is unlikely to be demonstrated in practice: it is obscured by the much larger variation that can be attributed to sampling of cases. In addition, even if a very large sample of cases could be studied, the small number of rating categories used does not permit seemingly very different models to be distinguished from one another.",
            "publicationTitle": "Medical Decision Making",
            "publisher": "",
            "place": "",
            "date": "1988 Jul-Sep",
            "volume": "8",
            "issue": "3",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "197-203",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Med Decis Making",
            "DOI": "",
            "citationKey": "",
            "url": "http://www.ncbi.nlm.nih.gov/pubmed/3398748",
            "accessDate": "2010-03-08T15:20:39Z",
            "PMID": "",
            "PMCID": "",
            "ISSN": "0272-989X",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "",
            "libraryCatalog": "NCBI PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 3398748",
            "tags": [
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                    "tag": "ROC Curve"
                },
                {
                    "tag": "smoothing"
                }
            ],
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