[ { "key": "WD6UMRMA", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/WD6UMRMA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/WD6UMRMA", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/6047/items/TMAE7QBB", "type": "application/json" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } } }, "data": { "key": "WD6UMRMA", "version": 1, "parentItem": "TMAE7QBB", "itemType": "attachment", "linkMode": "linked_url", "title": "2117", "accessDate": "2009-10-29T23:02:51Z", "url": "http://www.genetics.org/cgi/content/abstract/165/4/2117", "note": "", "contentType": "", "charset": "", "tags": [], "relations": {}, "dateAdded": "2009-10-29T23:02:51Z", "dateModified": "2009-10-29T23:02:51Z" } }, { "key": "TMAE7QBB", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/TMAE7QBB", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/TMAE7QBB", "type": "text/html" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } }, "creatorSummary": "Liu et al.", "parsedDate": "2003-12-01", "numChildren": 1 }, "data": { "key": "TMAE7QBB", "version": 1, "itemType": "journalArticle", "title": "Genetic Structure and Diversity Among Maize Inbred Lines as Inferred From DNA Microsatellites", "creators": [ { "creatorType": "author", "firstName": "Kejun", "lastName": "Liu" }, { "creatorType": "author", "firstName": "Major", "lastName": "Goodman" }, { "creatorType": "author", "firstName": "Spencer", "lastName": "Muse" }, { "creatorType": "author", "firstName": "J. Stephen", "lastName": "Smith" }, { "creatorType": "author", "firstName": "Ed", "lastName": "Buckler" }, { "creatorType": "author", "firstName": "John", "lastName": "Doebley" } ], "abstractNote": "Two hundred and sixty maize inbred lines, representative of the genetic diversity among essentially all public lines of importance to temperate breeding and many important tropical and subtropical lines, were assayed for polymorphism at 94 microsatellite loci. The 2039 alleles identified served as raw data for estimating genetic structure and diversity. A model-based clustering analysis placed the inbred lines in five clusters that correspond to major breeding groups plus a set of lines showing evidence of mixed origins. A \"phylogenetic\" tree was constructed to further assess the genetic structure of maize inbreds, showing good agreement with the pedigree information and the cluster analysis. Tropical and subtropical inbreds possess a greater number of alleles and greater gene diversity than their temperate counterparts. The temperate Stiff Stalk lines are on average the most divergent from all other inbred groups. Comparison of diversity in equivalent samples of inbreds and open-pollinated landraces revealed that maize inbreds capture <80% of the alleles in the landraces, suggesting that landraces can provide additional genetic diversity for maize breeding. The contributions of four different segments of the landrace gene pool to each inbred group's gene pool were estimated using a novel likelihood-based model. The estimates are largely consistent with known histories of the inbreds and indicate that tropical highland germplasm is poorly represented in maize inbreds. Core sets of inbreds that capture maximal allelic richness were defined. These or similar core sets can be used for a variety of genetic applications in maize.", "publicationTitle": "Genetics", "publisher": "", "place": "", "date": "December 1, 2003", "volume": "165", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "2117-2128", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Genetics", "DOI": "", "citationKey": "", "url": "http://www.genetics.org/cgi/content/abstract/165/4/2117", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2009-10-29T23:02:50Z", "dateModified": "2009-10-29T23:02:50Z" } }, { "key": "QCBTSGIH", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/QCBTSGIH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/QCBTSGIH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } }, "creatorSummary": "Yan et al.", "parsedDate": "2005", "numChildren": 0 }, "data": { "key": "QCBTSGIH", "version": 1, "itemType": "journalArticle", "title": "Transcription and Histone Modifications in the Recombination-Free Region Spanning a Rice Centromere", "creators": [ { "creatorType": "author", "firstName": "Huihuang", "lastName": "Yan" }, { "creatorType": "author", "firstName": "Weiwei", "lastName": "Jin" }, { "creatorType": "author", "firstName": "Kiyotaka", "lastName": "Nagaki" }, { "creatorType": "author", "firstName": "Shulan", "lastName": "Tian" }, { "creatorType": "author", "firstName": "Shu", "lastName": "Ouyang" }, { "creatorType": "author", "firstName": "C. Robin", "lastName": "Buell" }, { "creatorType": "author", "firstName": "Paul B", "lastName": "Talbert" }, { "creatorType": "author", "firstName": "Steven", "lastName": "Henikoff" }, { "creatorType": "author", "firstName": "Jiming", "lastName": "Jiang" } ], "abstractNote": "Centromeres are sites of spindle attachment for chromosome segregation. During meiosis, recombination is absent at centromeres and surrounding regions. To understand the molecular basis for recombination suppression, we have comprehensively annotated the 3.5-Mb region that spans a fully sequenced rice centromere. Although transcriptional analysis showed that the 750-kb CENH3-containing core is relatively deficient in genes, the recombination-free region differs little in gene density from flanking regions that recombine. Likewise, the density of transposable elements is similar between the recombination-free region and flanking regions. We also measured levels of histone H4 acetylation and histone H3 methylation at 176 genes within the 3.5-Mb span. Active genes showed enrichment of H4 acetylation and H3K4 dimethylation as expected, including genes within the core. Our inability to detect sequence or histone modification features that distinguish recombination-free regions from flanking regions that recombine suggest that recombination suppression is an epigenetic feature of centromeres maintained by the assembly of CENH3-containing nucleosomes within the core. CENH3-containing centrochromatin does not appear to be distinguished by a unique combination of H3 and H4 modifications. Rather, the varied distribution of histone modifications might reflect the composition and abundance of sequence elements that inhabit centromeric DNA.", "publicationTitle": "Plant Cell", "publisher": "", "place": "", "date": "2005", "volume": "17", "issue": "12", "section": "", "partNumber": "", "partTitle": "", "pages": "3227-3238", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "http://www.plantcell.org/cgi/content/abstract/17/12/3227", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2009-10-28T21:08:33Z", "dateModified": "2009-10-28T21:08:33Z" } }, { "key": "D2XNIQ6T", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/D2XNIQ6T", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/D2XNIQ6T", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/6047/items/Q4THTTCR", "type": "application/json" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } } }, "data": { "key": "D2XNIQ6T", "version": 1, "parentItem": "Q4THTTCR", "itemType": "attachment", "linkMode": "linked_url", "title": "login.aspx?direct=true&db=mnh&AN=16261189&site=ehost-live", "accessDate": "2009-10-28T21:00:37Z", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=16261189&site=ehost-live", "note": "", "contentType": "", "charset": "", "tags": [], "relations": {}, "dateAdded": "2009-10-28T21:00:49Z", "dateModified": "2009-10-28T21:00:49Z" } }, { "key": "7J8NGH8X", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/7J8NGH8X", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/7J8NGH8X", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/6047/items/Q4THTTCR", "type": "application/json" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "7J8NGH8X", "version": 1, "parentItem": "Q4THTTCR", "itemType": "note", "note": "Accession Number: 16261189 Language: English. Date Revised: 20081121. Date Created: 20051101. Date Completed: 20051213. Update Code: 20081217. Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review. Journal ID: 100962782. Publication Model: Print. Cited Medium: Print. NLM ISO Abbr: Nat. Rev. Mol. Cell Biol.", "tags": [], "relations": {}, "dateAdded": "2009-10-28T21:00:49Z", "dateModified": "2009-10-28T21:00:49Z" } }, { "key": "Q4THTTCR", "version": 1, "library": { "type": "group", "id": 6047, "name": "histone modification", "links": { "alternate": { "href": "https://www.zotero.org/groups/histone_modification", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/6047/items/Q4THTTCR", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/histone_modification/items/Q4THTTCR", "type": "text/html" } }, "meta": { "createdByUser": { "id": 62170, "username": "n8ls", "name": "Nate Ellis", "links": { "alternate": { "href": "https://www.zotero.org/n8ls", "type": "text/html" } } }, "creatorSummary": "Martin and Zhang", "parsedDate": "2005-11", "numChildren": 2 }, "data": { "key": "Q4THTTCR", "version": 1, "itemType": "journalArticle", "title": "The diverse functions of histone lysine methylation.", "creators": [ { "creatorType": "author", "firstName": "Cyrus", "lastName": "Martin" }, { "creatorType": "author", "firstName": "Yi", "lastName": "Zhang" } ], "abstractNote": "Covalent modifications of histone tails have fundamental roles in chromatin structure and function. One such modification, lysine methylation, has important functions in many biological processes that include heterochromatin formation, X-chromosome inactivation and transcriptional regulation. Here, we summarize recent advances in our understanding of how lysine methylation functions in these diverse biological processes, and raise questions that need to be addressed in the future.", "publicationTitle": "Nature Reviews. Molecular Cell Biology", "publisher": "", "place": "", "date": "November 2005", "volume": "6", "issue": "11", "section": "", "partNumber": "", "partTitle": "", "pages": "838-849", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Nat Rev Mol Cell Biol", "DOI": "", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=16261189&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1471-0072", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Animals" }, { "tag": "Gene Silencing*" }, { "tag": "Heterochromatin/*metabolism" }, { "tag": "Histone-Lysine N-Methyltransferase/*physiology" }, { "tag": "Histone-Lysine N-Methyltransferase/chemistry" }, { "tag": "Histones/*metabolism" }, { "tag": "Histones/chemistry" }, { "tag": "Lysine/metabolism" }, { "tag": "Methylation" }, { "tag": "Transcription, Genetic" }, { "tag": "Transcriptional Activation*" } ], "collections": [], "relations": {}, "dateAdded": "2009-10-28T21:00:49Z", "dateModified": "2009-10-28T21:00:49Z" } } ]