[ { "key": "RZAS9IA4", "version": 79, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/RZAS9IA4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/RZAS9IA4", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "Brochhausen et al.", "parsedDate": "2014", "numChildren": 0 }, "data": { "key": "RZAS9IA4", "version": 79, "itemType": "conferencePaper", "title": "Towards a foundational representation of potential drug-drug interaction knowledge", "creators": [ { "creatorType": "author", "firstName": "Mathias", "lastName": "Brochhausen" }, { "creatorType": "author", "firstName": "Jodi", "lastName": "Schneider" }, { "creatorType": "author", "firstName": "Daniel", "lastName": "Malone" }, { "creatorType": "author", "firstName": "Philip E", "lastName": "Empey" }, { "creatorType": "author", "firstName": "William R", "lastName": "Hogan" }, { "creatorType": "author", "firstName": "Richard D", "lastName": "Boyce" } ], "abstractNote": "", "proceedingsTitle": "First International Workshop on Drug Interaction Knowledge Representation (DIKR-2014) at the International Conference on Biomedical Ontologies (ICBO 2014)", "conferenceName": "", "publisher": "", "place": "", "date": "2014", "eventPlace": "", "volume": "", "issue": "", "numberOfVolumes": "", "pages": "", "series": "", "seriesNumber": "", "DOI": "", "ISBN": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2017-05-01T15:52:46Z", "dateModified": "2017-05-01T15:52:46Z" } }, { "key": "4W6DU3TJ", "version": 78, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/4W6DU3TJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/4W6DU3TJ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "Hachad et al.", "parsedDate": "2010-10", "numChildren": 1 }, "data": { "key": "4W6DU3TJ", "version": 78, "itemType": "journalArticle", "title": "A useful tool for drug interaction evaluation: the University of Washington Metabolism and Transport Drug Interaction Database", "creators": [ { "creatorType": "author", "firstName": "Houda", "lastName": "Hachad" }, { "creatorType": "author", "firstName": "Isabelle", "lastName": "Ragueneau-Majlessi" }, { "creatorType": "author", "firstName": "René H.", "lastName": "Levy" } ], "abstractNote": "The Metabolism and Transport Drug Interaction Database (http://www.druginteractioninfo.org) is a web-based research and analysis tool developed in the Department of Pharmaceutics at the University of Washington. The database has the largest manually curated collection of data related to drug interactions in humans. The tool integrates information from the literature, public repositories, reference textbooks, guideline documents, product prescribing labels and clinical review sections of new drug approval (NDA) packages. The database's easy-to-use web portal offers tools for visualisation, reporting and filtering of information. The database helps scientists to mine kinetics information for drug-metabolising enzymes and transporters, to assess the extent of in vivo drug interaction studies, as well as case reports for drugs, therapeutic proteins, food products and herbal derivatives. This review provides a brief description of the database organisation, its search functionalities and examples of use.", "publicationTitle": "Human Genomics", "publisher": "", "place": "", "date": "Oct 2010", "volume": "5", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "61-72", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Hum. Genomics", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1479-7364", "archive": "", "archiveLocation": "", "shortTitle": "A useful tool for drug interaction evaluation", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 21106490\nPMCID: PMC3500158", "tags": [ { "tag": "Databases, Factual", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Internet", "type": 1 }, { "tag": "Pharmaceutical Preparations", "type": 1 }, { "tag": "Pharmacokinetics", "type": 1 }, { "tag": "Receptors, Cytoplasmic and Nuclear", "type": 1 }, { "tag": "Search Engine", "type": 1 }, { "tag": "Universities", "type": 1 }, { "tag": "Washington", "type": 1 }, { "tag": "drug interactions", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2017-05-01T15:49:46Z", "dateModified": "2017-05-01T15:49:46Z" } }, { "key": "38RNVF73", "version": 78, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/38RNVF73", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/38RNVF73", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55386/items/4W6DU3TJ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } } }, "data": { "key": "38RNVF73", "version": 78, "parentItem": "4W6DU3TJ", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2017-05-01T15:49:46Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/21106490", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2017-05-01T15:49:46Z", "dateModified": "2017-05-01T15:49:46Z" } }, { "key": "MAW88CD9", "version": 77, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/MAW88CD9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/MAW88CD9", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55386/items/2IM72GUE", "type": "application/json" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } } }, "data": { "key": "MAW88CD9", "version": 77, "parentItem": "2IM72GUE", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2017-05-01T15:49:28Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/19401475", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2017-05-01T15:49:28Z", "dateModified": "2017-05-01T15:49:28Z" } }, { "key": "2IM72GUE", "version": 77, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/2IM72GUE", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/2IM72GUE", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "Leung et al.", "parsedDate": "2009-05", "numChildren": 1 }, "data": { "key": "2IM72GUE", "version": 77, "itemType": "journalArticle", "title": "Prevalence of use and the risk of adverse effects associated with complementary and alternative medicine in a cohort of patients receiving warfarin", "creators": [ { "creatorType": "author", "firstName": "Vivian W. Y.", "lastName": "Leung" }, { "creatorType": "author", "firstName": "Stephen J.", "lastName": "Shalansky" }, { "creatorType": "author", "firstName": "Melissa K.", "lastName": "Lo" }, { "creatorType": "author", "firstName": "Esther A.", "lastName": "Jadusingh" } ], "abstractNote": "BACKGROUND: The use of complementary and alternative medicine (CAM), including orally administered herbals, botanicals, vitamins, and supplements, may pose a risk to patients on warfarin therapy.\nOBJECTIVE: To estimate the prevalence of CAM use among patients taking warfarin and evaluate the impact of CAM exposure on the risk of warfarin-related adverse effects.\nMETHODS: A survey was administered to hospital inpatients and clinic outpatients on drug exposure (including CAM) over the previous month, self-reported bleeding events, use of alcohol and vitamin K-rich foods, and medical conditions. Prescription medication use was verified, and laboratory records were checked for out-of-range international normalized ratios (INRs) (defined as INR >4 or <2). The use of CAM, including products with reported or theoretical interactions with warfarin, was compared between patients with and without self-reported bleeding or out-of-range INR.\nRESULTS: Among the 314 patients who completed the survey, 44.3% reported using CAM at least weekly. Potentially interacting CAM was used by 34.1% of all patients, or 18.2% if vitamin E was excluded as an interacting CAM. Vitamin E was used by 24.2% of all patients and 71.0% of those who used potentially interacting CAM. There was no significant difference in CAM use or consumption of vitamin K-rich foods between patients with and without INRs greater than 4 or for patients with and without INRs less than 2.\nCONCLUSIONS: The use of potentially interacting CAM in this cohort was higher than the use previously reported among patients on warfarin therapy. However, exposure to CAM was not associated with an increase in the risk of self-reported bleeding or out-of-range INR.", "publicationTitle": "The Annals of Pharmacotherapy", "publisher": "", "place": "", "date": "May 2009", "volume": "43", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "875-881", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Ann Pharmacother", "DOI": "10.1345/aph.1L631", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1542-6270", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 19401475", "tags": [ { "tag": "Adult", "type": 1 }, { "tag": "Aged", "type": 1 }, { "tag": "Aged, 80 and over", "type": 1 }, { "tag": "Cohort Studies", "type": 1 }, { "tag": "Complementary Therapies", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Health Surveys", "type": 1 }, { "tag": "Hemorrhage", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "International Normalized Ratio", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Risk Factors", "type": 1 }, { "tag": "Warfarin", "type": 1 }, { "tag": "drug interactions", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2017-05-01T15:49:28Z", "dateModified": "2017-05-01T15:49:28Z" } }, { "key": "ENTKCSIH", "version": 77, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/ENTKCSIH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/ENTKCSIH", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55386/items/NTVWVQFK", "type": "application/json" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } } }, "data": { "key": "ENTKCSIH", "version": 77, "parentItem": "NTVWVQFK", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2017-05-01T15:49:12Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/24834100", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2017-05-01T15:49:12Z", "dateModified": "2017-05-01T15:49:12Z" } }, { "key": "NTVWVQFK", "version": 77, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/NTVWVQFK", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/NTVWVQFK", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "Kiefer et al.", "parsedDate": "2014", "numChildren": 1 }, "data": { "key": "NTVWVQFK", "version": 77, "itemType": "journalArticle", "title": "The Overlap of Dietary Supplement and Pharmaceutical Use in the MIDUS National Study", "creators": [ { "creatorType": "author", "firstName": "David S.", "lastName": "Kiefer" }, { "creatorType": "author", "firstName": "Joe C.", "lastName": "Chase" }, { "creatorType": "author", "firstName": "Gayle D.", "lastName": "Love" }, { "creatorType": "author", "firstName": "Bruce P.", "lastName": "Barrett" } ], "abstractNote": "Introduction. In the United States, dietary supplement (DS) use is common, often takes place outside of the purview of health care providers, and may involve DS in combination with pharmaceuticals. This situation has led to concerns about interactions between DS and pharmaceuticals, as well as the risks from polypharmacy and polysupplement use. Methods. We used data from the Midlife in the US study (MIDUS 2 Survey) to examine DS and prescription pharmaceutical use in 3876 study participants in order to determine the demographics of high-users (5 or more) of DS and pharmaceuticals and the presence of DS-pharmaceutical co-use. Results. Over 69% of study participants regularly used DS, 49.6% regularly used both DS and pharmaceuticals, and 6.3% and 8.7% were high-users of pharmaceuticals and DS, respectively. High-users of DS, pharmaceuticals, and either were more likely than the whole cohort to be female and of lower income. Conclusions. These findings corroborate those of other national studies with respect to the demographics of DS users but add new information about people at risk of DS-pharmaceutical interactions, not an insignificant proportion of the population examined by this dataset.", "publicationTitle": "Evidence-Based Complementary and Alternative Medicine: eCAM", "publisher": "", "place": "", "date": "2014", "volume": "2014", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "823853", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Evid Based Complement Alternat Med", "DOI": "10.1155/2014/823853", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1741-427X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 24834100\nPMCID: PMC4009205", "tags": [], "collections": [], "relations": {}, "dateAdded": "2017-05-01T15:49:12Z", "dateModified": "2017-05-01T15:49:12Z" } }, { "key": "K2H92AWG", "version": 76, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/K2H92AWG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/K2H92AWG", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "\"OHDSI Team\"", "parsedDate": "2016", "numChildren": 0 }, "data": { "key": "K2H92AWG", "version": 76, "itemType": "webpage", "title": "OHDSI/KnowledgeBaseWeb", "creators": [ { "creatorType": "author", "name": "\"OHDSI Team\"" } ], "abstractNote": "KnowledgeBase - Source code used to develop the OHDSI knowledge base of sources with information relevant for assessing assocations between drugs and health outcomes of interest.", "websiteTitle": "GitHub", "websiteType": "", "date": "2016", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "https://github.com/OHDSI/KnowledgeBaseWeb", "accessDate": "2016-07-29", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2016-05-11T18:45:38Z", "dateModified": "2016-10-31T14:37:57Z" } }, { "key": "SPRWJEJ3", "version": 75, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/SPRWJEJ3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/SPRWJEJ3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "\"OHDSI Team\"", "parsedDate": "2016", "numChildren": 0 }, "data": { "key": "SPRWJEJ3", "version": 75, "itemType": "webpage", "title": "WebAPI Overview and REST calls", "creators": [ { "creatorType": "author", "name": "\"OHDSI Team\"" } ], "abstractNote": "", "websiteTitle": "", "websiteType": "", "date": "2016", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.ohdsi.org/web/wiki/doku.php?id=documentation:software:splicer", "accessDate": "2016-05-11T18:46:58Z", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2016-05-11T18:46:58Z", "dateModified": "2016-10-31T14:36:12Z" } }, { "key": "27WNP3UH", "version": 74, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/27WNP3UH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/27WNP3UH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "Tatonetti et al.", "parsedDate": "2016", "numChildren": 0 }, "data": { "key": "27WNP3UH", "version": 74, "itemType": "webpage", "title": "Experimental LAERTES Evidence Base Explorer", "creators": [ { "creatorType": "author", "firstName": "Nicholas P.", "lastName": "Tatonetti" }, { "creatorType": "author", "firstName": "Benjamin", "lastName": "May" }, { "creatorType": "author", "firstName": "Richard D.", "lastName": "Boyce" } ], "abstractNote": "", "websiteTitle": "", "websiteType": "", "date": "2016", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.ohdsi.org/web/knowledgebaseweb/", "accessDate": "2016-07-29", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2016-05-11T18:43:43Z", "dateModified": "2016-07-29T09:19:55Z" } }, { "key": "Q2UZGI9H", "version": 70, "library": { "type": "group", "id": 55386, "name": "Biomedical-ontology", "links": { "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55386/items/Q2UZGI9H", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/biomedical-ontology/items/Q2UZGI9H", "type": "text/html" } }, "meta": { "createdByUser": { "id": 8771, "username": "boycer", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/boycer", "type": "text/html" } } }, "creatorSummary": "\"ISO\"", "parsedDate": "2007-12-15", "numChildren": 1 }, "data": { "key": "Q2UZGI9H", "version": 70, "itemType": "report", "title": "Information technology -- General-Purpose Datatypes (GPD)", "creators": [ { "creatorType": "author", "name": "\"ISO\"" } ], "abstractNote": "", "reportNumber": "ISO/IEC 11404:2007", "reportType": "", "institution": "", "place": "", "date": "12/15/2007", "seriesTitle": "", "seriesNumber": "", "pages": "", "DOI": "", "ISBN": "", "citationKey": "", "url": "http://www.iso.org/iso/home/store/catalogue_ics/catalogue_detail_ics.htm?csnumber=39479", "accessDate": "2016-05-21T12:45:05Z", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "ISO/IEC 11404", "language": "English", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2016-05-21T12:45:05Z", "dateModified": "2016-05-21T12:46:49Z" } }, { "key": "HBQ2JTUS", "version": 67, "library": { "type": "group", "id": 55386, "name": 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