[ { "key": "A26QAD2Q", "version": 34, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/A26QAD2Q", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/A26QAD2Q", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/4DZ9VHH3", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } } }, "data": { "key": "A26QAD2Q", "version": 34, "parentItem": "4DZ9VHH3", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2013-09-09T12:07:19Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/23885955", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-09-09T12:07:19Z", "dateModified": "2013-09-09T12:07:19Z" } }, { "key": "4DZ9VHH3", "version": 34, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/4DZ9VHH3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/4DZ9VHH3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Yao et al.", "parsedDate": "2013", "numChildren": 1 }, "data": { "key": "4DZ9VHH3", "version": 34, "itemType": "journalArticle", "title": "Global informetric perspective studies on translational medical research", "creators": [ { "creatorType": "author", "firstName": "Qiang", "lastName": "Yao" }, { "creatorType": "author", "firstName": "Peng-Hui", "lastName": "Lyu" }, { "creatorType": "author", "firstName": "Fei-Cheng", "lastName": "Ma" }, { "creatorType": "author", "firstName": "Lan", "lastName": "Yao" }, { "creatorType": "author", "firstName": "Shi-Jing", "lastName": "Zhang" } ], "abstractNote": "BACKGROUND: Translational medical research literature has increased rapidly in the last few decades and played a more and more important role during the development of medicine science. The main aim of this study is to evaluate the global performance of translational medical research during the past few decades.\nMETHODS: Bibliometric, social network analysis, and visualization technologies were used for analyzing translational medical research performance from the aspects of subject categories, journals, countries, institutes, keywords, and MeSH terms. Meanwhile, the co-author, co-words and cluster analysis methods were also used to trace popular topics in translational medical research related work.\nRESULTS: Research output suggested a solid development in translational medical research, in terms of increasing scientific production and research collaboration. We identified the core journals, mainstream subject categories, leading countries, and institutions in translational medical research. There was an uneven distribution of publications at authorial, institutional, and national levels. The most commonly used keywords that appeared in the articles were \"translational research\", \"translational medicine\", \"biomarkers\", \"stroke\", \"inflammation\", \"cancer\", and \"breast cancer\".\nCONCLUSIONS: The subject categories of \"Research & Experimental Medicine\", \"Medical Laboratory Technology\", and \"General & Internal Medicine\" play a key role in translational medical research both in production and in its networks. Translational medical research and CTS, etc. are core journals of translational research. G7 countries are the leading nations for translational medical research. Some developing countries, such as P.R China, also play an important role in the communication of translational research. The USA and its institutions play a dominant role in the production, collaboration, citations and high quality articles. The research trends in translational medical research involve drug design and development, pathogenesis and treatment of disease, disease model research, evidence-based research, and stem and progenitor cells.", "publicationTitle": "BMC medical informatics and decision making", "publisher": "", "place": "", "date": "2013", "volume": "13", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "77", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "BMC Med Inform Decis Mak", "DOI": "10.1186/1472-6947-13-77", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1472-6947", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 23885955", "tags": [ { "tag": "Bibliometrics", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Information Seeking Behavior", "type": 1 }, { "tag": "Social Networking", "type": 1 }, { "tag": "Systems Integration", "type": 1 }, { "tag": "Translational Medical Research", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2013-09-09T12:07:19Z", "dateModified": "2013-09-09T12:07:19Z" } }, { "key": "2FP353FS", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/2FP353FS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/2FP353FS", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "O'Grady", "parsedDate": "2012-10", "numChildren": 1 }, "data": { "key": "2FP353FS", "version": 1, "itemType": "journalArticle", "title": "What is knowledge and when should it be implemented?", "creators": [ { "creatorType": "author", "firstName": "Laura", "lastName": "O'Grady" } ], "abstractNote": "A primary purpose of research is to generate new knowledge. Scientific advances have progressively identified optimal ways to achieve this purpose. Included in this evolution are the notions of evidence-based medicine, decision aids, shared decision making, measurement and evaluation as well as implementation. The importance of including qualitative and quantitative methods in our research is now understood. We have debated the meaning of evidence and how to implement it. However, we have yet to consider how to include in our study findings other types of information such as tacit and experiential knowledge. This key consideration needs to take place before we translate new findings or 'knowledge' into clinical practice. This article critiques assumptions regarding the nature of knowledge and suggests a framework for implementing research findings into practice.", "publicationTitle": "Journal of evaluation in clinical practice", "publisher": "", "place": "", "date": "Oct 2012", "volume": "18", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "951-953", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Eval Clin Pract", "DOI": "10.1111/j.1365-2753.2012.01899.x", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1365-2753", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22994990", "tags": [], "collections": [], "relations": {}, "dateAdded": "2013-01-18T19:19:44Z", "dateModified": "2013-01-18T19:19:44Z" } }, { "key": "AR99W7IV", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/AR99W7IV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/AR99W7IV", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/2FP353FS", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } } }, "data": { "key": "AR99W7IV", "version": 1, "parentItem": "2FP353FS", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Link", "accessDate": "2013-01-18T19:19:44Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22994990", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-01-18T19:19:44Z", "dateModified": "2013-01-18T19:19:44Z" } }, { "key": "ICIPNWH5", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/ICIPNWH5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/ICIPNWH5", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/QTTRQM9M", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } } }, "data": { "key": "ICIPNWH5", "version": 1, "parentItem": "QTTRQM9M", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Link", "accessDate": "2013-01-18T19:17:25Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/23260775", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-01-18T19:17:25Z", "dateModified": "2013-01-18T19:17:25Z" } }, { "key": "QTTRQM9M", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/QTTRQM9M", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/QTTRQM9M", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Backus and Jones", "parsedDate": "2013-01", "numChildren": 1 }, "data": { "key": "QTTRQM9M", "version": 1, "itemType": "journalArticle", "title": "Maximizing research relevance to enhance knowledge translation", "creators": [ { "creatorType": "author", "firstName": "Deborah", "lastName": "Backus" }, { "creatorType": "author", "firstName": "Michael L", "lastName": "Jones" } ], "abstractNote": "This supplement focuses on an important issue in rehabilitation medicine: how to maximize research relevance in order to enhance knowledge translation into clinical practice. Authors provide insights into issues and barriers impacting effective translation of evidence into practice and provide useful guidance for rehabilitation researchers and practitioners on how to structure lines of inquiry to enhance clinical relevance. While this supplement will provide meaningful information to rehabilitation researchers, the content will also be of interest to clinicians, consumers of rehabilitation services, and reviewers for journals featuring rehabilitation research.", "publicationTitle": "Archives of physical medicine and rehabilitation", "publisher": "", "place": "", "date": "Jan 2013", "volume": "94", "issue": "1 Suppl", "section": "", "partNumber": "", "partTitle": "", "pages": "S1-2", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Arch Phys Med Rehabil", "DOI": "10.1016/j.apmr.2012.11.003", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1532-821X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 23260775", "tags": [], "collections": [], "relations": {}, "dateAdded": "2013-01-18T19:17:25Z", "dateModified": "2013-01-18T19:17:25Z" } }, { "key": "3W9KWVTD", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/3W9KWVTD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/3W9KWVTD", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/5JEM3V2I", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } } }, "data": { "key": "3W9KWVTD", "version": 1, "parentItem": "5JEM3V2I", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Link", "accessDate": "2013-01-18T19:16:39Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/23322363", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-01-18T19:16:39Z", "dateModified": "2013-01-18T19:16:39Z" } }, { "key": "5JEM3V2I", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/5JEM3V2I", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/5JEM3V2I", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Lam et al.", "parsedDate": "2013-01-15", "numChildren": 1 }, "data": { "key": "5JEM3V2I", "version": 1, "itemType": "journalArticle", "title": "\"Drivers\" of Translational Cancer Epidemiology in the 21st Century: Needs and Opportunities", "creators": [ { "creatorType": "author", "firstName": "Tram Kim", "lastName": "Lam" }, { "creatorType": "author", "firstName": "Margaret", "lastName": "Spitz" }, { "creatorType": "author", "firstName": "Sheri D", "lastName": "Schully" }, { "creatorType": "author", "firstName": "Muin J", "lastName": "Khoury" } ], "abstractNote": "Cancer epidemiology is at the cusp of a paradigm shift-propelled by an urgent need to accelerate the pace of translating scientific discoveries into health care and population health benefits. As part of a strategic planning process for cancer epidemiologic research, the Epidemiology and Genomics Research Program (EGRP) at the National Cancer Institute (NCI) is leading a \"longitudinal\" meeting with members of the research community to engage in an on-going dialogue to help shape and invigorate the field. Here, we review a translational framework influenced by \"drivers\" that we believe have begun guiding cancer epidemiology toward translation in the past few years and are most likely to drive the field further in the next decade. The drivers include: (i) collaboration and team science, (ii) technology, (iii) multilevel analyses and interventions, and (iv) knowledge integration from basic, clinical, and population sciences. Using the global prevention of cervical cancer as an example of a public health endeavor to anchor the conversation, we discuss how these drivers can guide epidemiology from discovery to population health impact, along the translational research continuum. Cancer Epidemiol Biomarkers Prev; 1-8. ©2013 AACR.", "publicationTitle": "Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology", "publisher": "", "place": "", "date": "Jan 15, 2013", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Cancer Epidemiol. Biomarkers Prev.", "DOI": "10.1158/1055-9965.EPI-12-1262", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1538-7755", "archive": "", "archiveLocation": "", "shortTitle": "\"Drivers\" of Translational Cancer Epidemiology in the 21st Century", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 23322363", "tags": [], "collections": [], "relations": {}, "dateAdded": "2013-01-18T19:16:39Z", "dateModified": "2013-01-18T19:16:39Z" } }, { "key": "JR7RMBFR", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/JR7RMBFR", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/JR7RMBFR", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/SI9SNC3I", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } } }, "data": { "key": "JR7RMBFR", "version": 1, "parentItem": "SI9SNC3I", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Link", "accessDate": "2013-01-18T19:10:15Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22898128", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-01-18T19:10:15Z", "dateModified": "2013-01-18T19:10:15Z" } }, { "key": "SI9SNC3I", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/SI9SNC3I", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/SI9SNC3I", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Tabak et al.", "parsedDate": "2012-09", "numChildren": 1 }, "data": { "key": "SI9SNC3I", "version": 1, "itemType": "journalArticle", "title": "Bridging research and practice: models for dissemination and implementation research", "creators": [ { "creatorType": "author", "firstName": "Rachel G", "lastName": "Tabak" }, { "creatorType": "author", "firstName": "Elaine C", "lastName": "Khoong" }, { "creatorType": "author", "firstName": "David A", "lastName": "Chambers" }, { "creatorType": "author", "firstName": "Ross C", "lastName": "Brownson" } ], "abstractNote": "CONTEXT\n\nTheories and frameworks (hereafter called models) enhance dissemination and implementation (D&I) research by making the spread of evidence-based interventions more likely. This work organizes and synthesizes these models by (1) developing an inventory of models used in D&I research; (2) synthesizing this information; and (3) providing guidance on how to select a model to inform study design and execution.\n\n\nEVIDENCE ACQUISITION\n\nThis review began with commonly cited models and model developers and used snowball sampling to collect models developed in any year from journal articles, presentations, and books. All models were analyzed and categorized in 2011 based on three author-defined variables: construct flexibility, focus on dissemination and/or implementation activities (D/I), and the socioecologic framework (SEF) level. Five-point scales were used to rate construct flexibility from broad to operational and D/I activities from dissemination-focused to implementation-focused. All SEF levels (system, community, organization, and individual) applicable to a model were also extracted. Models that addressed policy activities were noted.\n\n\nEVIDENCE SYNTHESIS\n\nSixty-one models were included in this review. Each of the five categories in the construct flexibility and D/I scales had at least four models. Models were distributed across all levels of the SEF; the fewest models (n=8) addressed policy activities. To assist researchers in selecting and utilizing a model throughout the research process, the authors present and explain examples of how models have been used.\n\n\nCONCLUSIONS\n\nThese findings may enable researchers to better identify and select models to inform their D&I work.", "publicationTitle": "American journal of preventive medicine", "publisher": "", "place": "", "date": "Sep 2012", "volume": "43", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "337-350", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Am J Prev Med", "DOI": "10.1016/j.amepre.2012.05.024", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1873-2607", "archive": "", "archiveLocation": "", "shortTitle": "Bridging research and practice", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22898128", "tags": [ { "tag": "Diffusion of Innovation", "type": 1 }, { "tag": "Evidence-Based Practice", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Models, Theoretical", "type": 1 }, { "tag": "Policy", "type": 1 }, { "tag": "Policy Making", "type": 1 }, { "tag": "Research", "type": 1 }, { "tag": "Research Design", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2013-01-18T19:10:15Z", "dateModified": "2013-01-18T19:10:15Z" } }, { "key": "5ZUTXQA4", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/5ZUTXQA4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/5ZUTXQA4", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/55192/items/U8KQKIVA", "type": "application/json" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { 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"alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Rubin and Zorumski", "parsedDate": "2012-03", "numChildren": 0 }, "data": { "key": "AJN7V9ZB", "version": 1, "itemType": "journalArticle", "title": "Perspective: Upcoming paradigm shifts for psychiatry in clinical care, research, and education", "creators": [ { "creatorType": "author", "firstName": "Eugene H", "lastName": "Rubin" }, { "creatorType": "author", "firstName": "Charles F", "lastName": "Zorumski" } ], "abstractNote": "Psychiatry is facing a crisis fueled by a fragmented and inefficient system of care delivery and a disconnection between the state of research and the state of psychiatry education and practice. Many factors contribute to the current state of psychiatric care. Psychiatry is a shortage specialty, and this will become worse in the near future. In addition, financial pressures have led to decreases in psychiatric inpatient and outpatient services and to shorter lengths of hospitalization for even the sickest patients. This has resulted in fragmented care and an overreliance on polypharmacy. To reach the large number of patients needing psychiatric services, health care systems must change and take advantage of collaborative and integrative care models and new technologies. Psychiatrists must learn to partner more effectively with primary care providers to extend their expertise to the greatest number of patients. Currently, psychiatric diagnosis is based on a criteria-based system that was developed in the 1970s. Advances in systems and molecular neuroscience are beginning to elucidate specific brain systems that are dysfunctional in psychiatric illness. This has the potential to revolutionize psychiatric diagnosis and treatment in the future. However, psychiatry has not yet been successful in incorporating the language of this research into clinically meaningful terminology. If neuroscientific progress is to be translated into clinical advances, this must change. Residency programs must better prepare their graduates to keep up with a psychiatry literature that will increasingly use the language of neural circuits to describe psychiatric symptomatology and treatments.", "publicationTitle": "Academic Medicine: Journal of the Association of American Medical Colleges", "publisher": "", "place": "", "date": "Mar 2012", "volume": "87", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "261-265", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Acad Med", "DOI": "10.1097/ACM.0b013e3182441697", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22373615", "accessDate": "2012-04-26T19:24:17Z", "PMID": "", "PMCID": "", "ISSN": "1938-808X", "archive": "", "archiveLocation": "", "shortTitle": "Perspective", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22373615", "tags": [ { "tag": "Brain", "type": 1 }, { "tag": "Cooperative Behavior", "type": 1 }, { "tag": "Curriculum", "type": 1 }, { "tag": "Delivery of Health Care, Integrated", "type": 1 }, { "tag": "Drug Therapy, Combination", "type": 1 }, { "tag": "Evidence-Based Medicine", "type": 1 }, { "tag": "Forecasting", "type": 1 }, { "tag": "Health Services Needs and Demand", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Interdisciplinary Communication", "type": 1 }, { "tag": "Mental Disorders", "type": 1 }, { "tag": "Neurosciences", "type": 1 }, { "tag": "Patient Care Team", "type": 1 }, { "tag": "Primary Health Care", "type": 1 }, { "tag": "Psychiatry", "type": 1 }, { "tag": "Psychotropic Drugs", "type": 1 }, { "tag": "Referral and Consultation", "type": 1 }, { "tag": "Translational Medical Research", "type": 1 }, { "tag": "United States", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2012-04-26T19:24:17Z", "dateModified": "2012-04-26T19:24:17Z" } }, { "key": "8E2HE4E3", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/8E2HE4E3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/8E2HE4E3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Roberts et al.", "parsedDate": "2012-03", "numChildren": 0 }, "data": { "key": "8E2HE4E3", "version": 1, "itemType": "journalArticle", "title": "Perspective: Transforming science into medicine: how clinician-scientists can build bridges across research's \"valley of death\"", "creators": [ { "creatorType": "author", "firstName": "Scott F", "lastName": "Roberts" }, { "creatorType": "author", "firstName": "Martin A", "lastName": "Fischhoff" }, { "creatorType": "author", "firstName": "Stacey A", "lastName": "Sakowski" }, { "creatorType": "author", "firstName": "Eva L", "lastName": "Feldman" } ], "abstractNote": "Significant increases in National Institutes of Health (NIH) spending on medical research have not produced corresponding increases in new treatments and cures. Instead, laboratory discoveries remain in what has been termed the \"valley of death,\" the gap between bench research and clinical application. Recently, there has been considerable discussion in the literature and scientific community about the causes of this phenomenon and how to bridge the abyss. In this article, the authors examine one possible explanation: Clinician-scientists' declining role in the medical research enterprise has had a dilatory effect on the successful translation of laboratory breakthroughs into new clinical applications. In recent decades, the percentage of MDs receiving NIH funding has drastically decreased compared with PhDs. The growing gap between the research and clinical enterprises has resulted in fewer scientists with a true understanding of clinical problems as well as scientists who are unable to or uninterested in gleaning new basic research hypotheses from failed clinical trials. The NIH and many U.S. medical schools have recognized the decline of the clinician-scientist as a major problem and adopted innovative programs to reverse the trend. However, more radical action may be required, including major changes to the NIH peer-review process, greater funding for translational research, and significantly more resources for the training, debt relief, and early career support of potential clinician-scientists. Such improvements are required for clinician-scientists to conduct translational research that bridges the valley of death and transforms biomedical research discoveries into tangible clinical treatments and technologies.", "publicationTitle": "Academic Medicine: Journal of the Association of American Medical Colleges", "publisher": "", "place": "", "date": "Mar 2012", "volume": "87", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "266-270", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Acad Med", "DOI": "10.1097/ACM.0b013e3182446fa3", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22373616", "accessDate": "2012-04-26T19:24:00Z", "PMID": "", "PMCID": "", "ISSN": "1938-808X", "archive": "", "archiveLocation": "", "shortTitle": "Perspective", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22373616", "tags": [ { "tag": "Academic Medical Centers", "type": 1 }, { "tag": "Career Choice", "type": 1 }, { "tag": "Diffusion of Innovation", "type": 1 }, { "tag": "Financing, Government", "type": 1 }, { "tag": "Forecasting", "type": 1 }, { "tag": "Health Services Needs and Demand", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Motivation", "type": 1 }, { "tag": "Physician's Role", "type": 1 }, { "tag": "Research Support as Topic", "type": 1 }, { "tag": "Science", "type": 1 }, { "tag": "Translational Medical Research", "type": 1 }, { "tag": "United States", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2012-04-26T19:24:00Z", "dateModified": "2012-04-26T19:24:00Z" } }, { "key": "4S23PQKW", "version": 1, "library": { "type": "group", "id": 55192, "name": "MLA_TR", "links": { "alternate": { "href": "https://www.zotero.org/groups/mla_tr", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/55192/items/4S23PQKW", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/mla_tr/items/4S23PQKW", "type": "text/html" } }, "meta": { "createdByUser": { "id": 446801, "username": "catsarli", "name": "Cathy Sarli", "links": { "alternate": { "href": "https://www.zotero.org/catsarli", "type": "text/html" } } }, "creatorSummary": "Gonzales et al.", "parsedDate": "2012-03", "numChildren": 0 }, "data": { "key": "4S23PQKW", "version": 1, "itemType": "journalArticle", "title": "A framework for training health professionals in implementation and dissemination science", "creators": [ { "creatorType": "author", "firstName": "Ralph", "lastName": "Gonzales" }, { "creatorType": "author", "firstName": "Margaret A", "lastName": "Handley" }, { "creatorType": "author", "firstName": "Sara", "lastName": "Ackerman" }, { "creatorType": "author", "firstName": "Patricia S", "lastName": "Oʼsullivan" } ], "abstractNote": "The authors describe a conceptual framework for implementation and dissemination science (IDS) and propose competencies for IDS training. Their framework is designed to facilitate the application of theories and methods from the distinct domains of clinical disciplines (e.g., medicine, public health), population sciences (e.g., biostatistics, epidemiology), and translational disciplines (e.g., social and behavioral sciences, business administration education). They explore three principles that guided the development of their conceptual framework: Behavior change among organizations and/or individuals (providers, patients) is inherent in the translation process; engagement of stakeholder organizations, health care delivery systems, and individuals is imperative to achieve effective translation and sustained improvements; and IDS research is iterative, benefiting from cycles and collaborative, bidirectional relationships. The authors propose seven domains for IDS training-team science, context identification, literature identification and assessment, community engagement, intervention design and research implementation, evaluation of effect of translational activity, behavioral change communication strategies-and define 12 IDS training competencies within these domains. As a model, they describe specific courses introduced at the University of California, San Francisco, which they designed to develop these competencies. The authors encourage other training programs and institutions to use or adapt the design principles, conceptual framework, and proposed competencies to evaluate their current IDS training needs and to support new program development.", "publicationTitle": "Academic Medicine: Journal of the Association of American Medical Colleges", "publisher": "", "place": "", "date": "Mar 2012", "volume": "87", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "271-278", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Acad Med", "DOI": "10.1097/ACM.0b013e3182449d33", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22373617", "accessDate": "2012-04-26T19:23:43Z", "PMID": "", "PMCID": "", "ISSN": "1938-808X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22373617", "tags": [ { "tag": "Clinical Competence", "type": 1 }, { "tag": "Communication", "type": 1 }, { "tag": "Community-Institutional Relations", "type": 1 }, { "tag": "Cooperative Behavior", "type": 1 }, { "tag": "Curriculum", "type": 1 }, { "tag": "Diffusion of Innovation", "type": 1 }, { "tag": "Education, Medical", "type": 1 }, { "tag": "Evidence-Based Medicine", "type": 1 }, { "tag": "Forecasting", "type": 1 }, { "tag": "Health Plan Implementation", "type": 1 }, { "tag": "Health Services Needs and Demand", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Information Dissemination", "type": 1 }, { "tag": "Interdisciplinary Communication", "type": 1 }, { "tag": "Translational Medical Research", "type": 1 }, { "tag": "United States", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2012-04-26T19:23:43Z", "dateModified": "2012-04-26T19:23:43Z" } } ]