Accession Number: 148507749; Source Info: Mar2021, Vol. 324 Issue 3, p74; Subject Term: MENTAL illness treatment; Subject Term: LEECH therapy; Subject Term: ENGRAVING; Subject Term: CHRISTMAS cards; Subject Term: GREETING cards; NAICS/Industry Codes: 453220 Gift, Novelty, and Souvenir Stores; NAICS/Industry Codes: 323111 Commercial Printing (except Screen and Books); NAICS/Industry Codes: 323119 Other printing; NAICS/Industry Codes: 418210 Stationery and office supplies merchant wholesalers; NAICS/Industry Codes: 424120 Stationery and Office Supplies Merchant Wholesalers; NAICS/Industry Codes: 511190 Other publishers; NAICS/Industry Codes: 511191 Greeting Card Publishers; Number of Pages: 1p; Illustrations: 3 Color Photographs, 1 Cartoon or Caricature; Document Type: Article; Full Text Word Count: 768
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "5DNKRXIF", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/5DNKRXIF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/5DNKRXIF", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "parsedDate": "2021-03", "numChildren": 1 }, "data": { "key": "5DNKRXIF", "version": 94, "itemType": "journalArticle", "title": "50, 100 & 150 YEARS AGO.", "creators": [], "abstractNote": "The article provides an overview of past publications of the periodical. Topics discussed include treatment of mental illness in the U.S.; universal use of leeches in surgery; and application of baby power to washing machines engraving belonging to John Highbarger. It also informs on politics on Christmas cards.", "publicationTitle": "Scientific American", "publisher": "", "place": "", "date": "2021-03", "volume": "324", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "74-74", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Scientific American", "DOI": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=148507749&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "00368733", "archive": "Academic Search Premier", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Scientific American", "tags": [ { "tag": "CHRISTMAS cards" }, { "tag": "ENGRAVING" }, { "tag": "GREETING cards" }, { "tag": "LEECH therapy" }, { "tag": "MENTAL illness treatment" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "QATNJ8AC", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/QATNJ8AC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/QATNJ8AC", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/R9FFRNUG", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "QATNJ8AC", "version": 94, "parentItem": "R9FFRNUG", "itemType": "note", "note": "Accession Number: 156566942; Stamler, Hannah; Source Info: Spring2022, Vol. 43 Issue 2, p1; Subject Term: LEECH therapy; Subject Term: BLOODLETTING; Subject Term: BRONCHITIS treatment; Subject Term: ANIMAL breeding; Subject Term: NORTH America; NAICS/Industry Codes: 112990 All Other Animal Production; NAICS/Industry Codes: 115210 Support Activities for Animal Production; Number of Pages: 1p; Illustrations: 1 Color Photograph; Document Type: Article; Full Text Word Count: 318
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "R9FFRNUG", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/R9FFRNUG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/R9FFRNUG", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Stamler", "parsedDate": "2022", "numChildren": 1 }, "data": { "key": "R9FFRNUG", "version": 94, "itemType": "journalArticle", "title": "Leech Mania: The humble worm was once a status symbol.", "creators": [ { "creatorType": "author", "firstName": "Hannah", "lastName": "Stamler" } ], "abstractNote": "The article informs that the ancient practice of bloodletting witnessed resurgence in Europe and North America in early 1800s as doctors prescribed leeches for a wide variety of ailments, from headaches to bronchitis. In Hungary, enterprising traders drained the kingdom's swamps to export approximately 60 tons annually. It is noted that demand for leeches was so high that nations without native leech populations started experimenting with artificial breeding.", "publicationTitle": "Humanities", "publisher": "", "place": "", "date": "2022", "volume": "43", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "1-1", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Humanities", "DOI": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=156566942&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "00187526", "archive": "Academic Search Premier", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Superintendent of Documents", "tags": [ { "tag": "ANIMAL breeding" }, { "tag": "BLOODLETTING" }, { "tag": "BRONCHITIS treatment" }, { "tag": "LEECH therapy" }, { "tag": "NORTH America" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "BZG75F7F", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/BZG75F7F", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/BZG75F7F", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/6FM259VF", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "BZG75F7F", "version": 94, "parentItem": "6FM259VF", "itemType": "note", "note": "Accession Number: 125712629; Cornejo, Agustin 1 Shammas, Ronnie L. 1 Poveromo, Luke P. 1 Hui-Jie Lee 2 Hollenbeck, Scott T. 1; Email Address: scott.hollenbeck@duke.edu; Affiliation: 1: Division of Plastic and Reconstructive Surgery, Duke University, Durham, North Carolina 2: Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina; Source Info: 2017, Vol. 33 Issue 9, p612; Subject Term: HYPEREMIA; Subject Term: LEECH therapy; Subject Term: PLASTIC surgery complications; Subject Term: TREATMENT effectiveness; Subject Term: SURGICAL flaps; Subject Term: THERAPEUTICS; Author-Supplied Keyword: Hirudo medicinalis; Author-Supplied Keyword: leech therapy; Author-Supplied Keyword: medicinal leech; Author-Supplied Keyword: venous congestion; Number of Pages: 7p; Document Type: Article
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "AWGCIHWE", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/AWGCIHWE", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/AWGCIHWE", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/TD3WHVE3", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "AWGCIHWE", "version": 94, "parentItem": "TD3WHVE3", "itemType": "note", "note": "Accession Number: 156401620; Malviya, Vikas 1 Golandaj, Vinay Kumar 1; Email Address: drvinay.surg2018@gmail.com Saini, Abhay 1 Dadsena, Narendra Kumar 1; Affiliation: 1: Department of General Surgery, L.N. Medical College and JK Hospital, JK Hospital Campus, Bhopal, Madhya Pradesh, India; Source Info: Feb2022, Vol. 84 Issue 1, p873; Subject Term: LEECH therapy; Subject Term: SALVAGE therapy; Author-Supplied Keyword: Flap; Author-Supplied Keyword: Hirudotherapy; Author-Supplied Keyword: Leech therapy; Author-Supplied Keyword: Venous congestion; Number of Pages: 6p; Document Type: Article; Full Text Word Count: 4187
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "TD3WHVE3", "version": 94, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/TD3WHVE3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/TD3WHVE3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Malviya et al.", "parsedDate": "2022-02", "numChildren": 1 }, "data": { "key": "TD3WHVE3", "version": 94, "itemType": "journalArticle", "title": "Evaluation of Leech Therapy in Salvage of Congested Flaps: a Series of Nine Cases.", "creators": [ { "creatorType": "author", "firstName": "Vikas", "lastName": "Malviya" }, { "creatorType": "author", "firstName": "Vinay Kumar", "lastName": "Golandaj" }, { "creatorType": "author", "firstName": "Abhay", "lastName": "Saini" }, { "creatorType": "author", "firstName": "Narendra Kumar", "lastName": "Dadsena" } ], "abstractNote": "Leech therapy or hirudotherapy is a well-recognized option for treatment of venous congestion in plastic and reconstructive surgery. It is clearly documented in our ancient Sanskrit text like 'Sushruta Samhita'. Recently, hirudotherapy has become an important modality in salvaging venous congested flaps. This prospective study of 1-year period was conducted at L.N. Medical College and J.K. Hospital, Bhopal, Central India. Leech therapy used in a total of nine patients in this study. Out of nine patients, five were males and four were females, with a mean age of 44 years (range 20 and 74 years). Free flaps were employed in two patients and pedicles flap was used in seven. Venous congestion in most of the patient appeared before 24 h. A number of leeches used ranged from 121 to 180 leeches per patient, with a mean of 150.8. The number of days of leeching was from 4 to 8 days, with a mean of 5.8 days. Blood transfusion required was from 1 to 5 units with a mean of 2.5 units. No local or systemic complications were observed in our study. The overall flap survival rate was 77.7% (7/9) with flap loss in two patients. Venous congestion is the most common cause of flap failure. Application of leech therapy is a helpful tool in salvaging the tissue transfer, not otherwise salvageable by surgical means. [ABSTRACT FROM AUTHOR]", "publicationTitle": "Indian Journal of Surgery", "publisher": "", "place": "", "date": "2022-02", "volume": "84", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "873-878", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Indian Journal of Surgery", "DOI": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=156401620&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "09722068", "archive": "Academic Search Premier", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Flap" }, { "tag": "Hirudotherapy" }, { "tag": "LEECH therapy" }, { "tag": "Leech therapy" }, { "tag": "SALVAGE therapy" }, { "tag": "Venous congestion" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:48Z", "dateModified": "2023-03-15T12:55:48Z" } }, { "key": "45RF3M7W", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/45RF3M7W", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/45RF3M7W", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Summers", "parsedDate": "2016", "numChildren": 1 }, "data": { "key": "45RF3M7W", "version": 93, "itemType": "thesis", "title": "Trp channels and endovanilloids: Implications for nociception in the medicinal leech", "creators": [ { "creatorType": "author", "firstName": "Torrie", "lastName": "Summers" } ], "abstractNote": "Pain and associated neuropathic conditions (e.g. hyperalgesia, allodynia) are highly prevalent, yet the basic mechanisms underlying how nociceptive pathways are modified are poorly understood. The goal of this dissertation is to contribute to the foundational understanding of nociception by exploring the physiological and behavioral role of both the Transient Receptor Vanilloid (TRP) channels and the endovanilloid (eVN) signaling molecules that are known to contribute to the detection and modulation of pain signals, using the model system of the leech. Physiological and behavioral experiments confirmed the presence of both a peripheral and central TRPV-like channel within the polymodal nociceptive neurons that was characterized by sensitivity to capsaicin and noxious heat. Capsaicin was found to elicit a nocifensive response in a concentration-dependent manner; specifically, reflexive withdrawal of the posterior sucker and locomotion away from the noxious stimuli. Further experiments also revealed, for the first time in any annelid, the presence of a TRPA-like channel that was characterized by sensitivity to mustard oil and moderate cold. A TRPA antagonist blocked the responses to both mustard oil and cold, while sensitizing the responses to heat, indicating a potential interaction between the TRPV and TRPA channels within the polymodal nociceptive neurons. Mustard oil was also found to elicit similar nocifensive responses in a concentration dependent manner. Experiments exploring the role of eVNs found behavioral evidence of opposing effects in which eVNs induced attenuation of nociceptive responses and a sensitization of non-nociceptive responses in uninjured animals that was TRPV-dependent. Subsequent experiments induced an injury to the leech's posterior sucker that resulted in a persistent sensitization to non-nociceptive stimuli (allodynia) and nociceptive stimuli (hyperalgesia). When eVN treatment was given to the injured animals three days after the induction of injury, there was an attenuation of the injury-induced hyperalgesia, but no effect was observed on the allodynia. Taken together, these results demonstrate the conservation of the pain pathway and the therapeutic potential and pitfalls of eVN treatment after injury. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "thesisType": "", "university": "ProQuest Information & Learning", "place": "", "date": "2016", "series": "", "seriesNumber": "", "numPages": "", "DOI": "", "ISBN": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2016-99020-321&site=ehost-live", "accessDate": "", "ISSN": "", "archive": "APA PsycInfo", "archiveLocation": "2016-99020-321", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "ISBN: 0419-4217\nIssue: 7-B(E)\nJournal Abbreviation: Dissertation Abstracts International: Section B: The Sciences and Engineering\nPublication Title: Dissertation Abstracts International: Section B: The Sciences and Engineering\nVolume: 76", "tags": [ { "tag": "Crabs" }, { "tag": "Pain" }, { "tag": "Pain Perception" }, { "tag": "Photoreceptors" }, { "tag": "Retina" }, { "tag": "Sensitization" }, { "tag": "concentration dependent manner" }, { "tag": "concentration-dependent manner" }, { "tag": "polymodal nociceptive neurons" }, { "tag": "posterior sucker" }, { "tag": "transient receptor" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "L274FS65", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/L274FS65", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/L274FS65", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/DVJMK23Q", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "L274FS65", "version": 93, "parentItem": "DVJMK23Q", "itemType": "note", "note": "Accession Number: 2018-11224-112. Other Journal Title: Dissertation Abstracts International. Partial author list: First Author & Affiliation: Beresic-Perrins, Rebecca Kathleen; Northern Arizona University, Biological Sciences, US. Release Date: 20180510. Publication Type: Dissertation Abstract (0400). Format Covered: Electronic. Document Type: Dissertation. Dissertation Number: AAI10686252. ISBN: 978-0355567526. Language: EnglishMajor Descriptor: Insects; Invertebrates. Minor Descriptor: Parental Attitudes. Classification: General Psychology (2100). Population: Animal (20). Methodology: Empirical Study; Quantitative Study.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "W77KTBBM", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/W77KTBBM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/W77KTBBM", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/238WHQJ8", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "W77KTBBM", "version": 93, "parentItem": "238WHQJ8", "itemType": "note", "note": "Accession Number: 2016-42143-211. Other Journal Title: Dissertation Abstracts International. Partial author list: First Author & Affiliation: Pipkin, Jason Elliott; University of California, San Diego, Neurosciences, US. Release Date: 20161212. Publication Type: Dissertation Abstract (0400). Format Covered: Electronic. Document Type: Dissertation. Dissertation Number: AAI3741018. ISBN: 978-1339331928. Language: EnglishMajor Descriptor: Animal Models; Ganglion Cells (Retina); Neurons; Synapses. Classification: Physiological Psychology & Neuroscience (2500). Population: Animal (20). Methodology: Empirical Study; Quantitative Study.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "238WHQJ8", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/238WHQJ8", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/238WHQJ8", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Pipkin", "parsedDate": "2016", "numChildren": 1 }, "data": { "key": "238WHQJ8", "version": 93, "itemType": "thesis", "title": "Untangling the ganglion: Connectomics in the medicinal leech", "creators": [ { "creatorType": "author", "firstName": "Jason Elliott", "lastName": "Pipkin" } ], "abstractNote": "The behaviors generated by neural circuits are constrained by the connectivity pattern among the neurons involved. Determining this connectivity pattern for circuits involving more than a handful of neurons becomes infeasible for physiological approaches that measure how the membrane potential of one neuron is affected by currents elicited in another. On the other hand, determining connectivity by anatomically discovering synapses is difficult due to the complicated and intertwining arbors that neurons possess. One approach to unravel this knotty problem is to image serial thin sections of neural tissue with an electron microscope. In this thesis, I describe the first application of large scale serial electron microscopy to the ganglion of the medicinal leech, Hirudo verbana. The leech ganglion is an ideal preparation for this experiment as it is compact enough in size that it is feasible to collect images spanning an entire ganglion. Here, I discuss results we collected from two image volumes of leech tissue. One spans a small region of adult ganglion neuropil, while the other includes an entire ganglion belonging to a juvenile leech. In these volumes, I reconstruct three-dimensional representations of neuronal arbors and locate the synapses between them. In Chapter 2, I show that we can differentiate neurons on the basis of where synaptic input and output sites are distributed throughout their arbors. In Chapter 3, I show that we can locate the synapses between pairs of neurons previously known to be connected, and that we can discover new synapses anatomically that are then recovered physiologically. Together, these results demonstrate the potential that this 'connectomics' approach has when applied to the already physiologically accessible leech ganglion. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "thesisType": "", "university": "ProQuest Information & Learning", "place": "", "date": "2016", "series": "", "seriesNumber": "", "numPages": "", "DOI": "", "ISBN": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2016-42143-211&site=ehost-live", "accessDate": "", "ISSN": "", "archive": "APA PsycInfo", "archiveLocation": "2016-42143-211", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "ISBN: 0419-4217\nIssue: 5-B(E)\nJournal Abbreviation: Dissertation Abstracts International: Section B: The Sciences and Engineering\nPublication Title: Dissertation Abstracts International: Section B: The Sciences and Engineering\nVolume: 77", "tags": [ { "tag": "Animal Models" }, { "tag": "Ganglion Cells (Retina)" }, { "tag": "Neurons" }, { "tag": "Synapses" }, { "tag": "ganglion" }, { "tag": "leech" }, { "tag": "neurons" }, { "tag": "synapses" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "7D756FCM", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/7D756FCM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/7D756FCM", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/45RF3M7W", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "7D756FCM", "version": 93, "parentItem": "45RF3M7W", "itemType": "note", "note": "Accession Number: 2016-99020-321. Other Journal Title: Dissertation Abstracts International. Partial author list: First Author & Affiliation: Summers, Torrie; U South Dakota, US. Release Date: 20160411. Correction Date: 20160620. Publication Type: Dissertation Abstract (0400). Format Covered: Electronic. Document Type: Dissertation. Dissertation Number: AAI3683608. ISBN: 978-1-321-58078-5. Language: EnglishMajor Descriptor: Pain Perception; Photoreceptors. Minor Descriptor: Crabs; Pain; Retina; Sensitization. Classification: Physiological Psychology & Neuroscience (2500); General Psychology (2100). Population: Human (10). Methodology: Empirical Study; Quantitative Study.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "6HR4R73K", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/6HR4R73K", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/6HR4R73K", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/EE2FKQY2", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "6HR4R73K", "version": 93, "parentItem": "EE2FKQY2", "itemType": "note", "note": "Accession Number: 2019-31839-009. PMID: 31058572 Other Journal Title: Journal of Speech & Hearing Research. Partial author list: First Author & Affiliation: Marcotte, Anne K.; Department of Communication Sciences and Special Education, University of Georgia, Athens, GA, US. Release Date: 20191212. Correction Date: 20221128. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Comment/Reply. Language: EnglishMajor Descriptor: Stuttering; Treatment. Minor Descriptor: Recovery (Disorders); Family History. Classification: Communication Disorders (3270); Speech & Language Therapy (3385). References Available: Y. Page Count: 5. Issue Publication Date: May, 2019. Publication History: Accepted Date: Jul 26, 2018; Revised Date: Apr 24, 2018; First Submitted Date: Nov 22, 2017. Copyright Statement: American Speech-Language-Hearing Association. 2019.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "EE2FKQY2", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/EE2FKQY2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/EE2FKQY2", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Marcotte", "parsedDate": "2019-05", "numChildren": 1 }, "data": { "key": "EE2FKQY2", "version": 93, "itemType": "journalArticle", "title": "The influence of treatment on children's recovery from stuttering: Comments on Kefalianos et al (2017) and Leech et al (2017)", "creators": [ { "creatorType": "author", "firstName": "Anne K.", "lastName": "Marcotte" } ], "abstractNote": "Purpose: Two studies published recently in this journal sought to expand on previous attempts to explain and predict young children’s recovery from stuttering. This letter addresses the influence of treatment on such research. Conclusions: Recent publications from Kefalianos et al. (2017) and Leech, Bernstein Ratner, Brown, and Weber (2017) added to previous information that gender and language ability (or language growth) may be related to children’s recovery from stuttering. The conclusions from both studies are difficult to interpret, however, because neither incorporated two factors known to influence children’s recovery: a family history of recovery and, especially, the type and timing of treatment. Consideration of these two articles therefore raises multiple empirical, theoretical, and clinical issues that deserve to be fully addressed if our discipline is seeking to understand and to maximize recovery for young children who stutter. (PsycInfo Database Record (c) 2022 APA, all rights reserved)", "publicationTitle": "Journal of Speech, Language, and Hearing Research", "publisher": "", "place": "", "date": "2019-05", "volume": "62", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "1364-1368", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Journal of Speech, Language, and Hearing Research", "DOI": "10.1044/2019_JSLHR-S-17-0437", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2019-31839-009&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1092-4388", "archive": "APA PsycInfo", "archiveLocation": "2019-31839-009", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: American Speech-Language-Hearing Assn", "tags": [ { "tag": "Family History" }, { "tag": "Recovery (Disorders)" }, { "tag": "Stuttering" }, { "tag": "Treatment" }, { "tag": "recovery" }, { "tag": "stuttering" }, { "tag": "treatment" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "DVJMK23Q", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/DVJMK23Q", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/DVJMK23Q", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Beresic-Perrins", "parsedDate": "2018", "numChildren": 1 }, "data": { "key": "DVJMK23Q", "version": 93, "itemType": "thesis", "title": "Systematics and parental care of glossiphoniid leeches", "creators": [ { "creatorType": "author", "firstName": "Rebecca Kathleen", "lastName": "Beresic-Perrins" } ], "abstractNote": "How did parental care behaviors evolve? Is parental care in invertebrates distinct from parental care in vertebrates? These two questions provide the framework for my dissertation. Parental care is a complex set of behaviors that increases the fitness of a parent and its offspring. Parental behavior is found throughout the animal kingdom and appears to be an ancient behavior evolving over millions of years. Even with a long evolutionary history of parental care behaviors in invertebrates, research is lacking in this largest group of organisms. My dissertation will examine the evolutionary history of parental care in leeches (Annelida: Hirudinida) including a review of the literature to update the patterns of parental care in the family Glossiphoniidae and explore the evolution of these behaviors. In the process of studying the life history and parental care behaviors of leeches, I noticed discrepancies between the published descriptions of morphology, life-history, and behaviors for the populations I was supposed to encounter in central and northern Arizona, and the individuals that comprised my research populations. To resolve this issue, I performed morphological and molecular analyses of the COI region of these questionable individuals from Montezuma Well, resulting in new descriptions of the two Helobdella spp (Helobdella blinni and Helobdella rexvanderfordi). On leeches confirmed to represent Helobdella modesta, I also performed a laboratory reciprocal transplant experiment among three Arizona populations to investigate how their aquatic environment might lead to local adaptions in life-history traits including adult survival, breeding, and fecundity. Local adaptations in life-history traits and behaviors may eventually result in allopatric speciation, increasing the number of undescribed Helobdella spp. (PsycINFO Database Record (c) 2018 APA, all rights reserved)", "thesisType": "", "university": "ProQuest Information & Learning", "place": "", "date": "2018", "series": "", "seriesNumber": "", "numPages": "", "DOI": "", "ISBN": "", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2018-11224-112&site=ehost-live", "accessDate": "", "ISSN": "", "archive": "APA PsycInfo", "archiveLocation": "2018-11224-112", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "ISBN: 0419-4217\nIssue: 4-B(E)\nJournal Abbreviation: Dissertation Abstracts International: Section B: The Sciences and Engineering\nPublication Title: Dissertation Abstracts International: Section B: The Sciences and Engineering\nVolume: 79", "tags": [ { "tag": "Insects" }, { "tag": "Invertebrates" }, { "tag": "Parental Attitudes" }, { "tag": "invertebrates" }, { "tag": "leeches" }, { "tag": "parental care" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "92ZBBD73", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/92ZBBD73", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/92ZBBD73", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/DB9AN9EI", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "92ZBBD73", "version": 93, "parentItem": "DB9AN9EI", "itemType": "note", "note": "Accession Number: 2011-15371-009. PMID: 21411566 Partial author list: First Author & Affiliation: Bisson, Giacomo; Neurobiology Sector, International School for Advanced Studies (SISSA), Trieste, Italy. Release Date: 20110829. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Journal Article. Language: EnglishMajor Descriptor: Collective Behavior; Social Interaction. Classification: Social & Instinctive Behavior (2440). Population: Animal (20). Methodology: Empirical Study; Quantitative Study. References Available: Y. Page Count: 13. Issue Publication Date: Jul, 2011. Publication History: First Posted Date: Mar 16, 2011; Accepted Date: Mar 11, 2011; First Submitted Date: Dec 6, 2010. Copyright Statement: The American Physiological Society. 2011.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "DB9AN9EI", "version": 93, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/DB9AN9EI", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/DB9AN9EI", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Bisson and Torre", "parsedDate": "2011-07", "numChildren": 1 }, "data": { "key": "DB9AN9EI", "version": 93, "itemType": "journalArticle", "title": "Statistical characterization of social interactions and collective behavior in medicinal leeches", "creators": [ { "creatorType": "author", "firstName": "Giacomo", "lastName": "Bisson" }, { "creatorType": "author", "firstName": "Vincent", "lastName": "Torre" } ], "abstractNote": "In the present manuscript we analyze the behavior and interactions among leeches in the same observation tank. Colored beads were glued onto their skin, so that their behavior could be followed and quantified. When 2 or 3 leeches were present in the observation tank, they searched around for a maximum of two hours and their motion and behavior were independent from those of their conspecifics. When the number of leeches in the tank was increased to 10, leeches were attracted to each other and exhibited episodes of highly correlated behavior. Solitary leeches injected with serotonin or dopamine increased the portion of time spent pseudo-swimming and crawling, respectively. The behavior of 3-5 leeches injected with serotonin was not statistically independent and leeches were attracted to their conspecifics and exhibited episodes of correlated behavior. Therefore, serotonin not only induces pseudo-swimming in leeches but also promotes social interactions, characterized by a mutual attraction and by episodes of correlated /collective behavior. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "publicationTitle": "Journal of Neurophysiology", "publisher": "", "place": "", "date": "2011-07", "volume": "106", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "78-90", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Journal of Neurophysiology", "DOI": "10.1152/jn.01043.2010", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2011-15371-009&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0022-3077", "archive": "APA PsycInfo", "archiveLocation": "2011-15371-009", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: American Physiological Society", "tags": [ { "tag": "Animals" }, { "tag": "Behavior, Animal" }, { "tag": "Collective Behavior" }, { "tag": "Dopamine" }, { "tag": "Leeches" }, { "tag": "Locomotion" }, { "tag": "Serotonin" }, { "tag": "Social Behavior" }, { "tag": "Social Interaction" }, { "tag": "collective behavior" }, { "tag": "medicinal leeches" }, { "tag": "social interactions" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "MUQTAAT3", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/MUQTAAT3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/MUQTAAT3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Gharbaran et al.", "parsedDate": "2012-11", "numChildren": 1 }, "data": { "key": "MUQTAAT3", "version": 92, "itemType": "journalArticle", "title": "Segmental and regional differences in neuronal expression of the leech Hox genes Lox1 and Lox2 during embryogenesis", "creators": [ { "creatorType": "author", "firstName": "Rajendra", "lastName": "Gharbaran" }, { "creatorType": "author", "firstName": "Gabriel O.", "lastName": "Aisemberg" }, { "creatorType": "author", "firstName": "Susana", "lastName": "Alvarado" } ], "abstractNote": "Using double immunofluorescence experiments, we described the expression of the leech Hox genes, Lox1 and Lox2 by central neurons that stained for either serotonin or the leech-specific neuronal marker, Laz1-1. The goal is to determine whether the segmental boundaries of Lox1 and Lox2 expression in identified neurons coincide with segmental and regional differences in the differentiation of these cells. A number of neurons described here have been previously identified. The anteromedial serotonergic neurons are restricted to rostral ganglion 1 (R1) to midbody ganglion 3 (M3), but only express Lox1 in M2 and M3. The posteromedial serotonergic neurons which are situated in all segments as bilateral pairs early in development, but later become unpaired starting at M3, expressed Lox1 only in M2 and M3, and Lox2 in M8 to M21, in all paired and unpaired stages. The Retzius neurons, which stain for serotonin, express Lox2 in M7 to M21 where they exhibit different morphologies from their segmental homologs of the sex ganglia in M5 and M6. The Laz1-1 immunoreactive (Laz1-1+) heart accessory-like neurons express Lox1 in M4 and Lox2 in M7 to M17, but not in their segmental homologs of the heart accessory (HA) neurons located exclusively in M5 and M6. Also, Laz1-1+ neurons, which we named Lz3 expressed Lox1 in M4 to M8 where they are unpaired, but express Lox2 in M9 to M16 where they are bilaterally paired. Other Laz1-1 cells show more restricted and isolated Lox1 and Lox2 expression patterns. These results suggest a role of Lox1 and/or Lox2 in defining the anteroposterior boundaries of segmentally iterated neurons. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "publicationTitle": "Cellular and Molecular Neurobiology", "publisher": "", "place": "", "date": "2012-11", "volume": "32", "issue": "8", "section": "", "partNumber": "", "partTitle": "", "pages": "1243-1253", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Cellular and Molecular Neurobiology", "DOI": "10.1007/s10571-012-9849-8", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2012-32221-003&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0272-4340", "archive": "APA PsycInfo", "archiveLocation": "2012-32221-003", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Springer", "tags": [ { "tag": "Animals" }, { "tag": "Biological Markers" }, { "tag": "Central Nervous System" }, { "tag": "Embryo" }, { "tag": "Embryonic Development" }, { "tag": "Gene Expression Regulation, Developmental" }, { "tag": "Genes" }, { "tag": "Genes, Homeobox" }, { "tag": "Homeodomain Proteins" }, { "tag": "Leeches" }, { "tag": "Neurons" }, { "tag": "Serotonin" }, { "tag": "Worms" }, { "tag": "biomarkers" }, { "tag": "embryogenesis" }, { "tag": "genes" }, { "tag": "leeches" }, { "tag": "neuronal expression" }, { "tag": "serotonin" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "I6LYSW95", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/I6LYSW95", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/I6LYSW95", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/7UXSD9N7", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "I6LYSW95", "version": 92, "parentItem": "7UXSD9N7", "itemType": "note", "note": "Accession Number: 2016-16711-007. PMID: 27030751 Partial author list: First Author & Affiliation: Pirschel, Friederice; Department for Neuroscience, University of Oldenburg, Oldenburg, Germany. Release Date: 20160425. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Journal Article. Language: EnglishMajor Descriptor: Mechanoreceptors; Neural Networks; Physiology; Tactual Perception. Classification: Psychophysiology (2560). Population: Animal (20). Methodology: Empirical Study; Quantitative Study. References Available: Y. Page Count: 12. Issue Publication Date: Mar 30, 2016. Publication History: Accepted Date: Feb 10, 2016; Revised Date: Feb 4, 2016; First Submitted Date: May 5, 2015. Copyright Statement: The Authors. 2016.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "7UXSD9N7", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/7UXSD9N7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/7UXSD9N7", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Pirschel and Kretzberg", "parsedDate": "2016-03-30", "numChildren": 1 }, "data": { "key": "7UXSD9N7", "version": 92, "itemType": "journalArticle", "title": "Multiplexed population coding of stimulus properties by leech mechanosensory cells", "creators": [ { "creatorType": "author", "firstName": "Friederice", "lastName": "Pirschel" }, { "creatorType": "author", "firstName": "Jutta", "lastName": "Kretzberg" } ], "abstractNote": "Sensory coding has long been discussed in terms of a dichotomy between spike timing and rate coding. However, recent studies found that in primate mechanoperception and other sensory systems, spike rates and timing of cell populations complement each other. They simultaneously carry information about different stimulus properties in a multiplexed way. Here, we present evidence for multiplexed encoding of tactile skin stimulation in the tiny population of leech mechanoreceptors, consisting of only 10 cells of two types with overlapping receptive fields. Each mechanoreceptor neuron of the leech varies spike count and response latency to both touch intensity and location, leading to ambiguous responses to different stimuli. Nevertheless, three different stimulus estimation techniques consistently reveal that the neuronal population allows reliable decoding of both stimulus properties. For the two mechanoreceptor types, the transient responses of T (touch) cells and the sustained responses of P (pressure) cells, the relative timing of the first spikes of two mechanoreceptors encodes stimulus location, whereas summed spike counts represent touch intensity. Differences between the cell types become evident in responses to combined stimulus properties. The best estimation performance for stimulus location is obtained from the relative first spike timing of the faster and temporally more precise T cells. Simultaneously, the sustained responses of P cells indicate touch intensity by summed spike counts and stimulus duration by the duration of spike responses. The striking similarities of these results with previous findings on primate mechanosensory afferents suggest multiplexed population coding as a general principle of somatosensation. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "publicationTitle": "The Journal of Neuroscience", "publisher": "", "place": "", "date": "2016-03-30", "volume": "36", "issue": "13", "section": "", "partNumber": "", "partTitle": "", "pages": "3636-3647", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "The Journal of Neuroscience", "DOI": "10.1523/JNEUROSCI.1753-15.2016", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2016-16711-007&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0270-6474", "archive": "APA PsycInfo", "archiveLocation": "2016-16711-007", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Society for Neuroscience", "tags": [ { "tag": "Mechanoreceptors" }, { "tag": "Neural Networks" }, { "tag": "Physiology" }, { "tag": "Tactual Perception" }, { "tag": "local bend network" }, { "tag": "mechanoreceptors" }, { "tag": "multiplexing" }, { "tag": "sensory coding" }, { "tag": "tactile" }, { "tag": "touch" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "6D5RZTBQ", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/6D5RZTBQ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/6D5RZTBQ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Zaccardi et al.", "parsedDate": "2012-04-01", "numChildren": 1 }, "data": { "key": "6D5RZTBQ", "version": 92, "itemType": "journalArticle", "title": "Molecular mechanisms of short-term habituation in the leech Hirudo medicinalis", "creators": [ { "creatorType": "author", "firstName": "Maria Luisa", "lastName": "Zaccardi" }, { "creatorType": "author", "firstName": "Riccardo", "lastName": "Mozzachiodi" }, { "creatorType": "author", "firstName": "Giovanna", "lastName": "Traina" }, { "creatorType": "author", "firstName": "Marcello", "lastName": "Brunelli" }, { "creatorType": "author", "firstName": "Rossana", "lastName": "Scuri" } ], "abstractNote": "Although habituation is ubiquitous in the animal kingdom, its underlying mechanisms remain poorly understood. In this study, we began to explore the molecular cascades underlying short-term habituation in the leech Hirudomedicinalis. In H. medicinalis, a training paradigm, consisting of low-frequency repetitive electrical stimulation of the skin, produces a gradual increase in the latency to swim that spontaneously recovers within 20–30 min. As first step in determining the molecular pathways in short-term habituation, we examined the role of Ca2+. Both Ca2+ influx through voltage-gated channels and Ca2+ release from intracellular stores were found to contribute to short-term habituation. The analysis of the downstream targets of elevated cytosolic Ca2+ revealed that the activation of the phosholipase A2 was required for the induction of short-term habituation. Finally, we reported that the recruitment of arachidonic acid metabolites, generated by the 5-lipoxygenase pathway, was also necessary for the induction of swim induction habituation. These results provide the framework for a comprehensive characterization of the molecular underpinnings of habituation. This outcome will allow us to compare the mechanisms of habituation with those underlying other forms of nonassociative learning in the leech, such as sensitization and dishabituation, and, more in general, with those governing habituation in different vertebrate and invertebrate model systems. (PsycInfo Database Record (c) 2020 APA, all rights reserved)", "publicationTitle": "Behavioural Brain Research", "publisher": "", "place": "", "date": "2012-04-01", "volume": "229", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "235-243", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Behavioural Brain Research", "DOI": "10.1016/j.bbr.2012.01.028", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2012-06065-030&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0166-4328", "archive": "APA PsycInfo", "archiveLocation": "2012-06065-030", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Elsevier Science", "tags": [ { "tag": "Amphibia" }, { "tag": "Analysis of Variance" }, { "tag": "Animals" }, { "tag": "Arachidonic Acid" }, { "tag": "Behavior, Animal" }, { "tag": "Calcium" }, { "tag": "Calcium Channel Blockers" }, { "tag": "Calcium Ions" }, { "tag": "Denervation" }, { "tag": "Electric Stimulation" }, { "tag": "Electroshock" }, { "tag": "Enzyme Inhibitors" }, { "tag": "Gallic Acid" }, { "tag": "Habituation" }, { "tag": "Habituation, Psychophysiologic" }, { "tag": "Hirudo medicinalis" }, { "tag": "Leeches" }, { "tag": "Models, Biological" }, { "tag": "Molecules" }, { "tag": "Nifedipine" }, { "tag": "Reaction Time" }, { "tag": "Swimming" }, { "tag": "Time Factors" }, { "tag": "Voltage-Gated Ion Channels" }, { "tag": "arachidonic acid" }, { "tag": "calcium ions" }, { "tag": "leeches" }, { "tag": "molecular mechanisms" }, { "tag": "short term habituation" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "D2XH3KDL", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/D2XH3KDL", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/D2XH3KDL", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Drago et al.", "parsedDate": "2014-10", "numChildren": 1 }, "data": { "key": "D2XH3KDL", "version": 92, "itemType": "journalArticle", "title": "Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium‐binding adapter molecule 1 (Iba1/alias Aif‐1)", "creators": [ { "creatorType": "author", "firstName": "Francesco", "lastName": "Drago" }, { "creatorType": "author", "firstName": "Pierre‐Eric", "lastName": "Sautière" }, { "creatorType": "author", "firstName": "Françoise", "lastName": "le Marrec‐Croq" }, { "creatorType": "author", "firstName": "Alice", "lastName": "Accorsi" }, { "creatorType": "author", "firstName": "Christelle", "lastName": "Van Camp" }, { "creatorType": "author", "firstName": "Michel", "lastName": "Salzet" }, { "creatorType": "author", "firstName": "Christophe", "lastName": "Lefebvre" }, { "creatorType": "author", "firstName": "Jacopo", "lastName": "Vizioli" } ], "abstractNote": "The Ionized calcium‐Binding Adapter molecule 1 (Iba1), also known as Allograft Inflammatory Factor 1 (AIF‐1), is a 17 kDa cytokine‐inducible protein, produced by activated macrophages during chronic transplant rejection and inflammatory reactions in Vertebrates. In mammalian central nervous system (CNS), Iba1 is a sensitive marker associated with activated macrophages/microglia and is upregulated following neuronal death or brain lesions. The medicinal leech Hirudo medicinalis is able to regenerate its CNS after injury, leading to a complete functional repair. Similar to Vertebrates, leech neuroinflammatory processes are linked to microglia activation and recruitment at the lesion site. We identified a gene, named Hmiba1, coding a 17.8 kDa protein showing high similarity with Vertebrate AIF‐1. The present work constitutes the first report on an Iba1 protein in the nervous system of an invertebrate. Immunochemistry and gene expression analyses showed that HmIba1, like its mammalian counterpart, is modulated in leech CNS by mechanical injury or chemical stimuli (ATP). We presently demonstrate that most of leech microglial cells migrating and accumulating at the lesion site specifically expressed the activation marker HmIba1. While the functional role of Iba1, whatever species, is still unclear in reactive microglia, this molecule appeared as a good selective marker of activated cells in leech and presents an interesting tool to investigate the functions of these cells during nerve repair events. (PsycINFO Database Record (c) 2016 APA, all rights reserved)", "publicationTitle": "Developmental Neurobiology", "publisher": "", "place": "", "date": "2014-10", "volume": "74", "issue": "10", "section": "", "partNumber": "", "partTitle": "", "pages": "987-1001", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Developmental Neurobiology", "DOI": "10.1002/dneu.22179", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2014-18392-001&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1932-8451", "archive": "APA PsycInfo", "archiveLocation": "2014-18392-001", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: John Wiley & Sons", "tags": [ { "tag": "Adenosine Triphosphate" }, { "tag": "Animals" }, { "tag": "Blotting, Western" }, { "tag": "Calcium Channel" }, { "tag": "Calcium-Binding Proteins" }, { "tag": "Central Nervous System" }, { "tag": "DNA-Binding Proteins" }, { "tag": "Ganglia, Invertebrate" }, { "tag": "Gene Expression" }, { "tag": "Hirudo medicinalis" }, { "tag": "Iba1" }, { "tag": "Immunohistochemistry" }, { "tag": "Invertebrates" }, { "tag": "Microglia" }, { "tag": "Neuroimmunomodulation" }, { "tag": "Proteins" }, { "tag": "Sequence Homology" }, { "tag": "allograft inflammatory factor 1" }, { "tag": "medicinal leech" }, { "tag": "microglia activation" }, { "tag": "nerve repair" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "CU2MS74U", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/CU2MS74U", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/CU2MS74U", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/469942/items/RSBRYNXZ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "CU2MS74U", "version": 92, "parentItem": "RSBRYNXZ", "itemType": "note", "note": "Accession Number: 2021-76648-001. Partial author list: First Author & Affiliation: Leech, Teghan; School of Psychology, Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA, Australia. Release Date: 20210916. Publication Type: Journal (0100), Peer Reviewed Journal (0110). Format Covered: Electronic. Document Type: Erratum/Correction. Language: EnglishMajor Descriptor: Intervention; Major Depression; Mental Health; Self-Management; Smartphones. Minor Descriptor: Auditory Stimulation; Mobile Applications; Mobile Health; Digital Interventions. Classification: Psychosocial & Personality Development (2840). ArtID: 106184. Issue Publication Date: Sep, 2021. Publication History: First Posted Date: Aug 6, 2021. Copyright Statement: All rights reserved. Elsevier Ltd. 2021.
", "tags": [], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } }, { "key": "RSBRYNXZ", "version": 92, "library": { "type": "group", "id": 469942, "name": "UConn Curriculum Services", "links": { "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/469942/items/RSBRYNXZ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/uconn_curriculum_services/items/RSBRYNXZ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2901562, "username": "katefuller", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/katefuller", "type": "text/html" } } }, "creatorSummary": "Leech et al.", "parsedDate": "2021-09", "numChildren": 1 }, "data": { "key": "RSBRYNXZ", "version": 92, "itemType": "journalArticle", "title": "'Mental health apps for adolescents and young adults: A systematic review of randomised controlled trials': Corrigendum", "creators": [ { "creatorType": "author", "firstName": "Teghan", "lastName": "Leech" }, { "creatorType": "author", "firstName": "Diana", "lastName": "Dorstyn" }, { "creatorType": "author", "firstName": "Amanda", "lastName": "Taylor" }, { "creatorType": "author", "firstName": "Wenjing", "lastName": "Li" } ], "abstractNote": "Reports an error in 'Mental health apps for adolescents and young adults: A systematic review of randomised controlled trials' by Teghan Leech, Diana Dorstyn, Amanda Taylor and Wenjing Li (Children and Youth Services Review, 2021[Aug], Vol 127[106073]). The authors regret that select data in Table 1 were misplaced (incorrect table row) for two studies. The corrected details are presented in an erratum. (The following abstract of the original article appeared in record [rid]2021-68231-001[/rid]). Objective: Smartphone applications (‘apps’) have the potential to improve the scalability of mental health interventions for young people, however, the effectiveness of stand-alone apps in mental health management remains unclear. This systematic review, with meta-analysis, provides an up-to-date summary of the available high-quality evidence. Methods: Eleven randomized controlled trials, involving a pooled sample of 1706 adolescents and young adults (age range 10 to 35 years), were identified from the Cochrane Library, Embase, Google Scholar, PsycINFO and PubMed databases. The reporting quality of studies was evaluated using the Cochrane Risk of Bias Tool 2.0 (RoB 2.0). Hedges’ g effect sizes with 95% confidence intervals, p values and heterogeneity statistics were additionally calculated using a random effects model. Results: Study reporting quality was sound, with no trials characterized as ‘high’ risk. App interventions produced significant symptom improvement across multiple outcomes, compared to wait-list or attention control conditions (depression gw = 0.52 [CI: 0.18–0.84], p = .01, k = 8; stress gw = 0.30 [CI: 0.06–0.53], p = .02, k = 2). Longer-term benefits could not be established (k = 4), although individual studies reported positive trends up to 6 months post. Age was not identified as a significant moderator. Conclusions: Smartphone apps hold promise as a stand-alone self-management tool in mental health service delivery. Further controlled trials with follow-up data are needed to confirm these findings as well as determine treatment engagement and effectiveness across diverse groups of participants. (PsycInfo Database Record (c) 2021 APA, all rights reserved)", "publicationTitle": "Children and Youth Services Review", "publisher": "", "place": "", "date": "2021-09", "volume": "128", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Children and Youth Services Review", "DOI": "10.1016/j.childyouth.2021.106184", "citationKey": "", "url": "https://ezproxy.lib.uconn.edu/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=psyh&AN=2021-76648-001&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0190-7409", "archive": "APA PsycInfo", "archiveLocation": "2021-76648-001", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "Publisher: Elsevier Science", "tags": [ { "tag": "Auditory Stimulation" }, { "tag": "Depression" }, { "tag": "Digital Interventions" }, { "tag": "Intervention" }, { "tag": "Major Depression" }, { "tag": "Mental Health" }, { "tag": "Mobile Applications" }, { "tag": "Mobile Health" }, { "tag": "Mobile health" }, { "tag": "Self-Management" }, { "tag": "Self-management" }, { "tag": "Smartphone" }, { "tag": "Smartphones" }, { "tag": "Technology" }, { "tag": "Youth" } ], "collections": [ "G6FXKWCW" ], "relations": {}, "dateAdded": "2023-03-15T12:55:47Z", "dateModified": "2023-03-15T12:55:47Z" } } ]