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            "creatorSummary": "Al-Khindi et al.",
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            "title": "Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Timour",
                    "lastName": "Al-Khindi"
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                {
                    "creatorType": "author",
                    "firstName": "R. Loch",
                    "lastName": "Macdonald"
                },
                {
                    "creatorType": "author",
                    "firstName": "Tom A.",
                    "lastName": "Schweizer"
                }
            ],
            "abstractNote": "BACKGROUND AND PURPOSE: Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency characterized by the accumulation of blood in the subarachnoid space surrounding the brain. The acute treatment of aSAH is well documented but less is known about the long-term effects of aSAH on cognition and day-to-day functioning.\nMETHODS: We reviewed all studies in the past 10 years that have focused on the effects of aSAH on cognition and day-to-day functioning.\nRESULTS: Sixty-one empirical studies examining cognitive and functional outcome in patients with aSAH met inclusion criteria. Survivors of aSAH commonly experience deficits in memory, executive function, and language. These cognitive impairments interact to affect patients' day-to-day functioning, including activities of daily living, instrumental activities of daily living, return to work, and quality of life. Deficits in cognition and day-to-day functioning are further compounded by depression, anxiety, fatigue, and sleep disturbances.\nCONCLUSIONS: Much remains to be learned about the brain changes underlying cognitive and functional deficits, including the role of diffuse brain damage and secondary complications like vasospasm and elevated intracranial pressure. A consideration of these issues is necessary to obtain a better understanding of how aSAH affects cognition and day-to-day functioning in the long-term.",
            "publicationTitle": "Stroke; a Journal of Cerebral Circulation",
            "publisher": "",
            "place": "",
            "date": "Aug 2010",
            "volume": "41",
            "issue": "8",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "e519-536",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Stroke",
            "DOI": "10.1161/STROKEAHA.110.581975",
            "citationKey": "",
            "url": "",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1524-4628",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "eng",
            "libraryCatalog": "PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 20595669",
            "tags": [
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                    "tag": "Cognition",
                    "type": 1
                },
                {
                    "tag": "Cognition Disorders",
                    "type": 1
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                {
                    "tag": "Executive Function",
                    "type": 1
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                    "type": 1
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                {
                    "tag": "Memory",
                    "type": 1
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                {
                    "tag": "Recovery of Function",
                    "type": 1
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                {
                    "tag": "Subarachnoid Hemorrhage",
                    "type": 1
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                {
                    "tag": "Treatment Outcome",
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            "creatorSummary": "Stienen et al.",
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            "title": "Current practice in neuropsychological outcome reporting after aneurysmal subarachnoid haemorrhage",
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                    "creatorType": "author",
                    "firstName": "Martin N.",
                    "lastName": "Stienen"
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                    "lastName": "Weisshaupt"
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                {
                    "creatorType": "author",
                    "firstName": "Javier",
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                {
                    "creatorType": "author",
                    "firstName": "Christian",
                    "lastName": "Fung"
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                {
                    "creatorType": "author",
                    "firstName": "Emanuela",
                    "lastName": "Keller"
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                {
                    "creatorType": "author",
                    "firstName": "Gerhard",
                    "lastName": "Hildebrandt"
                },
                {
                    "creatorType": "author",
                    "firstName": "Aline",
                    "lastName": "Studerus-Germann"
                },
                {
                    "creatorType": "author",
                    "firstName": "Rene",
                    "lastName": "Müri"
                },
                {
                    "creatorType": "author",
                    "firstName": "Klemens",
                    "lastName": "Gutbrod"
                },
                {
                    "creatorType": "author",
                    "firstName": "Stefan",
                    "lastName": "Bläsi"
                },
                {
                    "creatorType": "author",
                    "firstName": "Andreas U.",
                    "lastName": "Monsch"
                },
                {
                    "creatorType": "author",
                    "firstName": "Peter",
                    "lastName": "Brugger"
                },
                {
                    "creatorType": "author",
                    "firstName": "Christian",
                    "lastName": "Mondadori"
                },
                {
                    "creatorType": "author",
                    "firstName": "Martin",
                    "lastName": "Sailer"
                },
                {
                    "creatorType": "author",
                    "firstName": "Philippe",
                    "lastName": "Bijlenga"
                },
                {
                    "creatorType": "author",
                    "firstName": "Karl",
                    "lastName": "Schaller"
                },
                {
                    "creatorType": "author",
                    "firstName": "Bawarjan",
                    "lastName": "Schatlo"
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                {
                    "creatorType": "author",
                    "name": "Swiss SOS study group"
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            ],
            "abstractNote": "BACKGROUND: Neuropsychological deficits (NPD) are common in patients with aneurysmal subarachnoid haemorrhage (aSAH). NPD are one of the major limiting factors for patients with an otherwise acceptable prognosis for sustained quality of life. There are only a few studies reporting outcome after aSAH, which used a standardized neuropsychological test battery as a primary or secondary outcome measure. Aim of this study was to determine the current practice of reporting NPD following aSAH in clinical studies.\nMETHODS: A MEDLINE analysis was performed using the search term \"subarachnoid haemorrhage outcome\". The latest 1,000 articles were screened. We recorded study design, number of patients, and the presence of neuropsychological outcome report. Additionally, the time of testing after aSAH, the neuropsychological tests administered, as well as the percentage of patients with NPD were analyzed.\nRESULTS: A total of 324 publications between 2009 and 2012 were selected for further review. Of those, 21 studies (6.5%) reported neuropsychological outcome, in 2,001 of 346,666 patients (0.6%). The assessment of NPD differed broadly using both subjective and objective cognitive evaluation, and a large variety of tests were used.\nCONCLUSION: Neuropsychological outcome is underreported, and there is great variety in assessment in currently published clinical articles on aSAH. Prospective randomized trials treating aSAH may benefit from implementing more comprehensive and standardized neuropsychological outcome measures. This approach might identify otherwise unnoticed treatment effects in future interventional studies of aSAH patients.",
            "publicationTitle": "Acta Neurochirurgica",
            "publisher": "",
            "place": "",
            "date": "Nov 2013",
            "volume": "155",
            "issue": "11",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "2045-2051",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Acta Neurochir (Wien)",
            "DOI": "10.1007/s00701-013-1823-9",
            "citationKey": "",
            "url": "",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "0942-0940",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "eng",
            "libraryCatalog": "PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 23887856",
            "tags": [
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                    "tag": "Clinical Trials as Topic",
                    "type": 1
                },
                {
                    "tag": "Humans",
                    "type": 1
                },
                {
                    "tag": "MEDLINE",
                    "type": 1
                },
                {
                    "tag": "Neuropsychological Tests",
                    "type": 1
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                {
                    "tag": "Prospective Studies",
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                {
                    "tag": "Subarachnoid Hemorrhage",
                    "type": 1
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                    "tag": "Treatment Outcome",
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            "creatorSummary": "Passier et al.",
            "parsedDate": "2011-06",
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        "data": {
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            "version": 3,
            "itemType": "journalArticle",
            "title": "Predicting fatigue 1 year after aneurysmal subarachnoid hemorrhage",
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                {
                    "creatorType": "author",
                    "firstName": "P. E. C. A.",
                    "lastName": "Passier"
                },
                {
                    "creatorType": "author",
                    "firstName": "M. W. M.",
                    "lastName": "Post"
                },
                {
                    "creatorType": "author",
                    "firstName": "M. J. E.",
                    "lastName": "van Zandvoort"
                },
                {
                    "creatorType": "author",
                    "firstName": "G. J. E.",
                    "lastName": "Rinkel"
                },
                {
                    "creatorType": "author",
                    "firstName": "E.",
                    "lastName": "Lindeman"
                },
                {
                    "creatorType": "author",
                    "firstName": "J. M. A.",
                    "lastName": "Visser-Meily"
                }
            ],
            "abstractNote": "Fatigue is an important contributor to quality of life in patients who survive aneurysmal subarachnoid hemorrhage (SAH), but the determinants of this fatigue are unclear. We assessed the occurrence of fatigue 1 year after SAH and its relation to physical or cognitive impairment, passive coping, and emotional problems, measured 3 months after SAH. This was a prospective cohort study of 108 patients who visited our SAH outpatient clinic 3 months after SAH and who were living independently in the community 1 year after SAH. Fatigue was evaluated using the Fatigue Severity Scale (FSS). Analysis of variance was used to analyze the data. Fatigue (FSS ≥ 4) was present in 77 patients (71%). Mean FSS scores were 4.1 (SD 1.6) in the group of patients having 'neither physical nor cognitive impairment,' 5.2 (1.4) having 'either physical or cognitive impairment,' and 5.9 (0.9) having 'both physical and cognitive impairments.' Mean FSS scores were higher in patients scoring high on passive coping (85 vs. 58%; RR 1.46, 95% CI 1.13-1.87), anxiety (84 vs. 55%; RR 1.53, 95% CI 1.17-2.02), or depression (85 vs. 62%; RR 1.36, 95% CI 1.08-1.72) than in patients without these complaints. Relationships between these complaints and FSS scores were higher in patients having neither physical nor cognitive impairments than in patients having physical or cognitive impairments. Fatigue is common after SAH and is related to physical and cognitive impairments. In patients with neither physical nor cognitive impairments, passive coping style and emotional problems are important predictors of fatigue.",
            "publicationTitle": "Journal of Neurology",
            "publisher": "",
            "place": "",
            "date": "Jun 2011",
            "volume": "258",
            "issue": "6",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "1091-1097",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "J. Neurol.",
            "DOI": "10.1007/s00415-010-5891-y",
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            "url": "",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1432-1459",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "",
            "language": "eng",
            "libraryCatalog": "PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 21207050",
            "tags": [
                {
                    "tag": "Adult",
                    "type": 1
                },
                {
                    "tag": "Aged",
                    "type": 1
                },
                {
                    "tag": "Analysis of Variance",
                    "type": 1
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                {
                    "tag": "Cognition Disorders",
                    "type": 1
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                {
                    "tag": "Fatigue",
                    "type": 1
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                {
                    "tag": "Female",
                    "type": 1
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                {
                    "tag": "Follow-Up Studies",
                    "type": 1
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                {
                    "tag": "Glasgow Outcome Scale",
                    "type": 1
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                {
                    "tag": "Humans",
                    "type": 1
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                    "tag": "Male",
                    "type": 1
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                    "type": 1
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