[ { "key": "ZKDXV8TS", "version": 4221, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/ZKDXV8TS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/ZKDXV8TS", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/9G3S33II", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "ZKDXV8TS", "version": 4221, "parentItem": "9G3S33II", "itemType": "attachment", "linkMode": "imported_url", "title": "PubMed Central Full Text PDF", "accessDate": "2023-03-06T21:06:08Z", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058770/pdf/10195_2019_Article_541.pdf", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Hosny - 2020 - Limb lengthening history, evolution, complications.pdf", "md5": "d658399042736dbcf5cd653ca056696a", "mtime": 1678136768000, "tags": [], "relations": {}, "dateAdded": "2023-03-06T21:06:08Z", "dateModified": "2023-03-06T21:06:08Z" } }, { "key": "9IQBWHXD", "version": 4220, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/9IQBWHXD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/9IQBWHXD", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/9G3S33II", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "9IQBWHXD", "version": 4220, "parentItem": "9G3S33II", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Central Link", "accessDate": "2023-03-06T21:06:06Z", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058770/", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2023-03-06T21:06:06Z", "dateModified": "2023-03-06T21:06:06Z" } }, { "key": "9G3S33II", "version": 4220, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/9G3S33II", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/9G3S33II", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Hosny", "parsedDate": "2020-12", "numChildren": 2 }, "data": { "key": "9G3S33II", "version": 4220, "itemType": "journalArticle", "title": "Limb lengthening history, evolution, complications and current concepts", "creators": [ { "creatorType": "author", "firstName": "Gamal A.", "lastName": "Hosny" } ], "abstractNote": "Limb lengthening continues to be a real challenge to both the patient and the orthopaedic surgeon. Although it is not a difficult operative problem, there is a long and exhausting postoperative commitment which can jeopardize early good results. I aim to review the history, evolution, biology, complications and current concepts of limb lengthening. Ilizarov’s innovative procedure using distraction histeogenesis is the mainstay of all newly developing methods of treatment. The method of fixation is evolving rapidly from unilateral external fixator to ring fixator, computer assisted and finally lengthening intramedullary nails. The newly manufactured nails avoid many of the drawbacks of external fixation but they have their own complications. In general, the indications for limb lengthening are controversial. The indications have been extended from lower limb length inequality to upper extremity lengthening, including humeral, forearm and phalangeal lengthening. A wide range in frequency of complications is recorded in the English literature, which may reach up to 100% of cases treated. With developing experience, cosmetic lengthening has become possible using external or internal lengthening devices with an acceptable rate of problems., Level of evidence: V.", "publicationTitle": "Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology", "publisher": "", "place": "", "date": "2020-12", "volume": "21", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "3", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Orthop Traumatol", "DOI": "10.1186/s10195-019-0541-3", "citationKey": "", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058770/", "accessDate": "2023-03-06T21:06:05Z", "PMID": "", "PMCID": "", "ISSN": "1590-9921", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "PubMed Central", "callNumber": "", "rights": "", "extra": "PMID: 32140790\nPMCID: PMC7058770", "tags": [], "collections": [], "relations": {}, "dateAdded": "2023-03-06T21:06:05Z", "dateModified": "2023-03-06T21:06:05Z" } }, { "key": "GMFBAMHD", "version": 4219, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/GMFBAMHD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/GMFBAMHD", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/6PML4Q56", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "GMFBAMHD", "version": 4219, "parentItem": "6PML4Q56", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T20:35:40Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/17377186", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T20:35:40Z", "dateModified": "2022-06-02T20:35:40Z" } }, { "key": "6PML4Q56", "version": 4219, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/6PML4Q56", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/6PML4Q56", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Okuma et al.", "parsedDate": "2007-03", "numChildren": 1 }, "data": { "key": "6PML4Q56", "version": 4219, "itemType": "journalArticle", "title": "Factors contributing to cavitation after CT-guided percutaneous radiofrequency ablation for lung tumors", "creators": [ { "creatorType": "author", "firstName": "Tomohisa", "lastName": "Okuma" }, { "creatorType": "author", "firstName": "Toshiyuki", "lastName": "Matsuoka" }, { "creatorType": "author", "firstName": "Akira", "lastName": "Yamamoto" }, { "creatorType": "author", "firstName": "Yoshimasa", "lastName": "Oyama" }, { "creatorType": "author", "firstName": "Kiyotoshi", "lastName": "Inoue" }, { "creatorType": "author", "firstName": "Kenji", "lastName": "Nakamura" }, { "creatorType": "author", "firstName": "Yuichi", "lastName": "Inoue" } ], "abstractNote": "PURPOSE: Cavitation has been described in lung neoplasms after radiofrequency ablation (RFA). In this retrospective study, the frequency and timing of cavitation after RFA of unresectable lung tumors was analyzed to determine the factors that contribute to cavitation and to assess the clinical course of patients who develop cavitation.\nMATERIALS AND METHODS: The authors retrospectively studied 100 lung RFA lesions in 48 patients (37 men, 11 women, age 69.7 years +/- 10.7, mean +/- SD) who underwent lung RFA between June 2000 and March 2006. RFA was performed using a LeVeen electrode inserted under guidance by computed tomography (CT). Follow-up consisted of CT performed at 1 week, 1 month, and every 2 to 3 months thereafter to determine the frequency of, time of radiographic appearance of, and factors contributing to cavity formation and the clinical course after cavitation.\nRESULTS: Cavitation was detected by CT at 1.5 months +/- 0.8 after RFA (14 sessions). No symptoms were noted in 12 sessions, but high fever developed after 1 month in two sessions. The frequency of cavitation was significantly higher in patients with lung cancer as the primary lesion (10/14), those who underwent RFA for lesions located within 1 cm of the chest wall (11/14), and those with pulmonary emphysema (7/14) (P < .05). Age, sex, maximum power output,total ablation time, minimum impedance, and tumor diameter were not significant contributors to cavity formation.\nCONCLUSIONS: In our study, cavitation occurred at a frequency of 14% at 1.5 months +/- 0.8 after RFA ablation, but the majority of patients were asymptomatic. Cavitation seems to occur more frequently in patients with a lesion near the chest wall, lung cancer as the primary lesion, and in those with pulmonary emphysema at baseline before the lung RFA.", "publicationTitle": "Journal of vascular and interventional radiology: JVIR", "publisher": "", "place": "", "date": "2007-03", "volume": "18", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "399-404", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Vasc Interv Radiol", "DOI": "10.1016/j.jvir.2007.01.004", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1535-7732", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 17377186", "tags": [ { "tag": "Aged", "type": 1 }, { "tag": "Catheter Ablation", "type": 1 }, { "tag": "Comorbidity", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Japan", "type": 1 }, { "tag": "Lung Neoplasms", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Pneumothorax", "type": 1 }, { "tag": "Radiography, Interventional", "type": 1 }, { "tag": "Risk Assessment", "type": 1 }, { "tag": "Risk Factors", "type": 1 }, { "tag": "Tomography, X-Ray Computed", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T20:35:39Z", "dateModified": "2022-06-02T20:35:39Z" } }, { "key": "NZPX2TZ6", "version": 4218, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/NZPX2TZ6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/NZPX2TZ6", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/MC3AXSBF", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "NZPX2TZ6", "version": 4218, "parentItem": "MC3AXSBF", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T20:30:22Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/35641416", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T20:30:22Z", "dateModified": "2022-06-02T20:30:22Z" } }, { "key": "MC3AXSBF", "version": 4218, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/MC3AXSBF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/MC3AXSBF", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Tomita et al.", "parsedDate": "2022-05-28", "numChildren": 1 }, "data": { "key": "MC3AXSBF", "version": 4218, "itemType": "journalArticle", "title": "Early enlarging cavitation after percutaneous radiofrequency ablation of lung tumors: Incidence, risk factors and outcome", "creators": [ { "creatorType": "author", "firstName": "Koji", "lastName": "Tomita" }, { "creatorType": "author", "firstName": "Toshihiro", "lastName": "Iguchi" }, { "creatorType": "author", "firstName": "Yusuke", "lastName": "Matsui" }, { "creatorType": "author", "firstName": "Mayu", "lastName": "Uka" }, { "creatorType": "author", "firstName": "Noriyuki", "lastName": "Umakoshi" }, { "creatorType": "author", "firstName": "Toshiharu", "lastName": "Mitsuhashi" }, { "creatorType": "author", "firstName": "Jun", "lastName": "Sakurai" }, { "creatorType": "author", "firstName": "Hideo", "lastName": "Gobara" }, { "creatorType": "author", "firstName": "Susumu", "lastName": "Kanazawa" }, { "creatorType": "author", "firstName": "Takao", "lastName": "Hiraki" } ], "abstractNote": "PURPOSE: The purpose of this study was to retrospectively determine the incidence of early enlarging cavitation after percutaneous radiofrequency ablation (RFA) of lung tumor and identify risk factors associated with their occurrence.\nPATIENTS AND METHODS: A total of 245 patients (140 men, 105 women; mean age, 62.7 ± 11.8 [SD] years; age range: 31-87 years) with 605 lung tumors who were treated using 401 RFA sessions from April 2010 to March 2020 were included. Of which, 31 patients with 38 early enlarging cavitation and control group (151 patients with 228 tumors) were analyzed. Early enlarging cavitation was defined as cavities with an enlarged size (>3 cm) occurring on ablated lesions within seven days after RFA. Incidence of cavitation, risk and post-procedural factors of occurrence, major adverse events (AEs) that occurred in RFA sessions with cavitation, and course of cavitation were evaluated. AEs were classified using the CIRSE classification system for complications.\nRESULTS: Thirty-eight cavities (6.3%, 38/605 tumors) in 31 patients occurred in an average of 3.1 ± 1.7 days (range, 1-7 days) after 32 RFA sessions. Distance from pleura ≥ 20 mm, contact with vessel ≥ 3 mm, multitined expandable electrode ≥ 3 cm, and bronchus ≥ 2 mm encompassed in the ablation zone were independent risk factors of occurrence. Fever ≥ 38.5 °C, white blood cell count ≥ 10,000/μl one day after RFA, and steroid therapy were independent post-procedural factors of occurrence. Twenty-four Grade 3 and two Grade 6 AEs occurred. Twenty-nine cavities disappeared within a mean duration of 111.9 ± 64.9 (SD) days (range: 44-274 days) and four remained with a mean follow-up of 279.2 ± 174 (SD) days; five patients were lost to follow-up.\nCONCLUSIONS: Early enlarging cavitation occurs in 6.3% of lung tumors treated with RFA and are associated with 26 major AEs in 32 sessions. Aforementioned procedural factors and post-procedural inflammation were significant risk factors of occurrence.", "publicationTitle": "Diagnostic and Interventional Imaging", "publisher": "", "place": "", "date": "2022-05-28", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "S2211-5684(22)00094-8", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Diagn Interv Imaging", "DOI": "10.1016/j.diii.2022.05.004", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "2211-5684", "archive": "", "archiveLocation": "", "shortTitle": "Early enlarging cavitation after percutaneous radiofrequency ablation of lung tumors", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 35641416", "tags": [ { "tag": "Adverse events", "type": 1 }, { "tag": "Lung neoplasms", "type": 1 }, { "tag": "Radiofrequency ablation", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T20:30:20Z", "dateModified": "2022-06-02T20:30:20Z" } }, { "key": "CV9U3JH7", "version": 4217, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/CV9U3JH7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/CV9U3JH7", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/WME4JR2B", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "CV9U3JH7", "version": 4217, "parentItem": "WME4JR2B", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T19:17:29Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25960147", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T19:17:29Z", "dateModified": "2022-06-02T19:17:29Z" } }, { "key": "WME4JR2B", "version": 4217, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/WME4JR2B", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/WME4JR2B", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Johnson and Brace", "parsedDate": "2015", "numChildren": 1 }, "data": { "key": "WME4JR2B", "version": 4217, "itemType": "journalArticle", "title": "Heat transfer within hydrodissection fluids: An analysis of thermal conduction and convection using liquid and gel materials", "creators": [ { "creatorType": "author", "firstName": "Alexander", "lastName": "Johnson" }, { "creatorType": "author", "firstName": "Christopher", "lastName": "Brace" } ], "abstractNote": "Interventional oncology procedures such as thermal ablation are becoming widely used for many tumours in the liver, kidney and lung. Thermal ablation refers to the focal destruction of tissue by generating cytotoxic temperatures in the treatment zone. Hydrodissection - separating tissues with fluids - protects healthy tissues adjacent to the ablation treatment zone to improve procedural safety, and facilitate more aggressive power application or applicator placement. However, fluids such as normal saline and 5% dextrose in water (D5W) can migrate into the peritoneum, reducing their protective efficacy. As an alternative, a thermo-gelable poloxamer 407 (P407) solution has been recently developed to facilitate hydrodissection procedures. We hypothesise that the P407 gel material does not provide convective heat dissipation from the ablation site, and therefore may alter the heat transfer dynamics compared to liquid materials during hydrodissection-assisted thermal ablation. The purpose of this study was to investigate the heat dissipation mechanics within D5W, liquid P407 and gel P407 hydrodissection barriers. Overall it was shown that the gel P407 dissipated heat primarily through conduction, whereas the liquid P407 and D5W dissipated heat through convection. Furthermore, the rate of temperature change within the gel P407 was greater than liquid P407 and D5W. Testing to evaluate the in vivo efficacy of the fluids with different modes of heat dissipation seems warranted for further study.", "publicationTitle": "International Journal of Hyperthermia: The Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group", "publisher": "", "place": "", "date": "2015", "volume": "31", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "551-559", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Int J Hyperthermia", "DOI": "10.3109/02656736.2015.1037799", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1464-5157", "archive": "", "archiveLocation": "", "shortTitle": "Heat transfer within hydrodissection fluids", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25960147", "tags": [ { "tag": "Ablation", "type": 1 }, { "tag": "Convection", "type": 1 }, { "tag": "Gels", "type": 1 }, { "tag": "Hot Temperature", "type": 1 }, { "tag": "Hyperthermia, Induced", "type": 1 }, { "tag": "Polyanetholesulfonate", "type": 1 }, { "tag": "Thermal Conductivity", "type": 1 }, { "tag": "heat dissipation", "type": 1 }, { "tag": "hydrodissection", "type": 1 }, { "tag": "poloxamer 407", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T19:17:28Z", "dateModified": "2022-06-02T19:17:28Z" } }, { "key": "VTV3IFUC", "version": 4216, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/VTV3IFUC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/VTV3IFUC", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/5T3ZDU9C", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "VTV3IFUC", "version": 4216, "parentItem": "5T3ZDU9C", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:49:11Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22268207", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:49:11Z", "dateModified": "2022-06-02T15:49:11Z" } }, { "key": "5T3ZDU9C", "version": 4216, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/5T3ZDU9C", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/5T3ZDU9C", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Moon et al.", "parsedDate": "2012-02", "numChildren": 1 }, "data": { "key": "5T3ZDU9C", "version": 4216, "itemType": "journalArticle", "title": "Chronologic change in the growth plate after radiofrequency-induced thermal injury: MRI-histologic correlation", "creators": [ { "creatorType": "author", "firstName": "Sung Gyu", "lastName": "Moon" }, { "creatorType": "author", "firstName": "Heung Sik", "lastName": "Kang" }, { "creatorType": "author", "firstName": "Sung-Hwan", "lastName": "Hong" }, { "creatorType": "author", "firstName": "Na Ra", "lastName": "Kim" }, { "creatorType": "author", "firstName": "Joon Woo", "lastName": "Lee" }, { "creatorType": "author", "firstName": "So Dug", "lastName": "Lim" } ], "abstractNote": "OBJECTIVE: The purposes of this study were to assess chronologic changes in normal growth plate after radiofrequency-induced thermal injury and to evaluate the feasibility of MRI for revealing alteration of the growth plate.\nMATERIALS AND METHODS: Radiofrequency ablation was performed on the right proximal tibia of 13 8-week-old New Zealand White rabbits. An 18-gauge cooled-tip electrode with a 5-mm active tip was placed distal to the physis under fluoroscopic guidance. MRI, including T1- and T2-weighted images, gradient-recalled echo images, and contrast-enhanced T1-weighted images, was performed 2, 4, and 12 weeks after ablation. Rabbits were sacrificed 2 (n = 4), 4 (n = 4), and 12 weeks (n = 5) after ablation. The sequential changes in the ablated zone, the injured physis, and the nonablated portion of the physis were correlated between MRI features and histologic results.\nRESULTS: Diameter of the nonenhancing lesion on MR images strongly correlated with the size of the region of coagulation necrosis at gross examination. The intraclass correlation coefficients were 0.98 and 0.94 for the long and short axes (p < 0.001). On gradient-recalled echo images, physial conspicuity was less in the injured physis than in the nonablated portion and less in the ablated than the control tibia. Physial conspicuity was graded for comparison with physial thickness at microscopic examination. The thickness of the physis was less in the ablated than in the control tibia 4 and 12 weeks after treatment (p < 0.05, paired Student t test). The cartilage column of the injured physis was delaminated 2 weeks after treatment, and a bone bridge through the injured physis was detected at 4 weeks.\nCONCLUSION: Radiofrequency-induced thermal injury causes early closure of the physis. MRI can depict the extent of radiofrequency-induced thermal injury and alterations in the physis that lead to early closure.", "publicationTitle": "AJR. American journal of roentgenology", "publisher": "", "place": "", "date": "2012-02", "volume": "198", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "W163-172", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "AJR Am J Roentgenol", "DOI": "10.2214/AJR.11.6774", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1546-3141", "archive": "", "archiveLocation": "", "shortTitle": "Chronologic change in the growth plate after radiofrequency-induced thermal injury", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22268207", "tags": [ { "tag": "Analysis of Variance", "type": 1 }, { "tag": "Animals", "type": 1 }, { "tag": "Catheter Ablation", "type": 1 }, { "tag": "Contrast Media", "type": 1 }, { "tag": "Gadolinium DTPA", "type": 1 }, { "tag": "Growth Plate", "type": 1 }, { "tag": "Magnetic Resonance Imaging", "type": 1 }, { "tag": "Rabbits", "type": 1 }, { "tag": "Salter-Harris Fractures", "type": 1 }, { "tag": "Tibia", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:49:10Z", "dateModified": "2022-06-02T15:49:10Z" } }, { "key": "ECU2YX4F", "version": 4214, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/ECU2YX4F", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/ECU2YX4F", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/V8ECHKBE", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "ECU2YX4F", "version": 4214, "parentItem": "V8ECHKBE", "itemType": "attachment", "linkMode": "imported_url", "title": "Full Text", "accessDate": "2022-06-02T15:46:49Z", "url": "https://europepmc.org/articles/pmc4164874?pdf=render", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Shiguetomi-Medina et al. - 2014 - Thermal epiphysiodesis performed with radio freque.pdf", "md5": "14d162fdff5c934df9c80331454b891b", "mtime": 1654184809000, "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:46:49Z", "dateModified": "2022-06-02T15:46:49Z" } }, { "key": "CXGFMAGW", "version": 4212, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/CXGFMAGW", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/CXGFMAGW", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/V8ECHKBE", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "CXGFMAGW", "version": 4212, "parentItem": "V8ECHKBE", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:46:43Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25036720", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:46:43Z", "dateModified": "2022-06-02T15:46:43Z" } }, { "key": "V8ECHKBE", "version": 4212, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/V8ECHKBE", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/V8ECHKBE", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Shiguetomi-Medina et al.", "parsedDate": "2014-09", "numChildren": 2 }, "data": { "key": "V8ECHKBE", "version": 4212, "itemType": "journalArticle", "title": "Thermal epiphysiodesis performed with radio frequency in a porcine model", "creators": [ { "creatorType": "author", "firstName": "Juan M.", "lastName": "Shiguetomi-Medina" }, { "creatorType": "author", "firstName": "Ole", "lastName": "Rahbek" }, { "creatorType": "author", "firstName": "Ahmed Abdul-Hussein", "lastName": "Abood" }, { "creatorType": "author", "firstName": "Hans", "lastName": "Stødkilde-Jørgensen" }, { "creatorType": "author", "firstName": "Bjarne", "lastName": "Møller-Madsen" } ], "abstractNote": "BACKGROUND AND PURPOSE: Current techniques for epiphysiodesis involve opening of cortical windows; use of staples, screws, and tension devices; and fusion with curettes or drills. Complications may have serious consequences. There is a need for a more reliable, precise, and less traumatic procedure that overcomes the known complications from existing techniques. We analyzed a new epiphysiodesis technique using radio-frequency ablation (RFA) in a porcine model.\nMETHODS: Six 35-kg and two 25-kg immature pigs were used. 1 hind leg of each animal was randomly selected and the proximal tibia growth plate was ablated laterally and medially. The contralateral leg was used as a control. MR images were obtained immediately after the ablation and 12 weeks later for 6 animals, and 24 weeks later for the other 2 animals. CT was done for the 2 animals that were followed for 24 weeks for proof of bone bridges.\nRESULTS: Both tibias were equal in length initially. At the 12-week follow-up, there was an average leg length discrepancy of 3.9 mm (95% CI: 3.0-4.8), and at 24 weeks the difference was 8.4 mm and 7.5 mm. No damage to the adjacent tissue was found. Bone bridges and physeal closure were found after 24 weeks. The pigs showed no discomfort after the intervention.\nINTERPRETATION: We found RFA to be feasible for epiphysiodesis in a pig model. The method is minimally invasive and recovery may be quick compared to conventional methods. We recommend that the method should be tested in larger-scale safety studies before clinical application.", "publicationTitle": "Acta Orthopaedica", "publisher": "", "place": "", "date": "2014-09", "volume": "85", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "538-542", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Acta Orthop", "DOI": "10.3109/17453674.2014.939014", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1745-3682", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25036720\nPMCID: PMC4164874", "tags": [ { "tag": "Ablation Techniques", "type": 1 }, { "tag": "Animals", "type": 1 }, { "tag": "Disease Models, Animal", "type": 1 }, { "tag": "Epiphyses", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Growth Plate", "type": 1 }, { "tag": "Leg Length Inequality", "type": 1 }, { "tag": "Magnetic Resonance Imaging", "type": 1 }, { "tag": "Radiosurgery", "type": 1 }, { "tag": "Swine", "type": 1 }, { "tag": "Tibia", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:46:42Z", "dateModified": "2022-06-02T15:46:42Z" } }, { "key": "HUU4BBS4", "version": 4210, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/HUU4BBS4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/HUU4BBS4", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/7BT8JBGH", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "HUU4BBS4", "version": 4210, "parentItem": "7BT8JBGH", "itemType": "attachment", "linkMode": "imported_url", "title": "Full Text", "accessDate": "2022-06-02T15:45:01Z", "url": "https://europepmc.org/articles/pmc2882017?pdf=render", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Widmann et al. - 2010 - Percutaneous radiofrequency epiphysiodesis in a ra.pdf", "md5": "546a9646429030f99c08e9906353e9a5", "mtime": 1654184701000, "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:45:01Z", "dateModified": "2022-06-02T15:45:01Z" } }, { "key": "XP4XNX4A", "version": 4209, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/XP4XNX4A", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/XP4XNX4A", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/7BT8JBGH", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "XP4XNX4A", "version": 4209, "parentItem": "7BT8JBGH", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:44:59Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/20306164", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:44:59Z", "dateModified": "2022-06-02T15:44:59Z" } }, { "key": "7BT8JBGH", "version": 4209, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/7BT8JBGH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/7BT8JBGH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Widmann et al.", "parsedDate": "2010-07", "numChildren": 2 }, "data": { "key": "7BT8JBGH", "version": 4209, "itemType": "journalArticle", "title": "Percutaneous radiofrequency epiphysiodesis in a rabbit model: a pilot study", "creators": [ { "creatorType": "author", "firstName": "Roger F.", "lastName": "Widmann" }, { "creatorType": "author", "firstName": "Terry D.", "lastName": "Amaral" }, { "creatorType": "author", "firstName": "Cemil", "lastName": "Yildiz" }, { "creatorType": "author", "firstName": "Xu", "lastName": "Yang" }, { "creatorType": "author", "firstName": "Mathias", "lastName": "Bostrom" } ], "abstractNote": "BACKGROUND: Techniques for epiphysiodesis have evolved from open surgical techniques requiring direct observation of the physis to percutaneous techniques performed with fluoroscopy.\nQUESTIONS/PURPOSES: Our purposes were to (1) describe a new minimally invasive surgical technique used to achieve epiphysiodesis using radiofrequency ablation, (2) document the effect of radiofrequency ablation on tibia length at 2, 6, and 12 weeks after ablation in a skeletally immature rabbit model, and (3) assess the effects of radiofrequency ablation on the histologic appearance of the proximal tibia physis and proximal tibia articular cartilage.\nMATERIALS AND METHODS: We performed epiphysiodesis of the rabbit proximal tibia on 15 skeletally immature male New Zealand White rabbits using a 22-gauge radiofrequency probe. The probe was positioned percutaneously and heated to 90 degrees C for 4 minutes on the medial and lateral (1/2) of the physis. The opposite tibia was used as a control. Five animals were sacrificed at 2, 6, or 12 weeks postoperatively. Tibia length was compared using Faxitron(R) radiographs and electronic calipers. Histology of the growth plate was assessed with light microscopy.\nRESULTS: We observed differences in tibia length between 4.16 mm and 11.59 mm (average 7.86 mm) at 12 weeks. The proximal tibia physis closed radiographically and histologically in all animals by 12 weeks. Histologic analysis showed no evidence of articular cartilage injury.\nCONCLUSIONS: This technique was reproducible and resulted in bone fusion of the rabbit proximal tibial growth plate. The use of radiofrequency ablation as described in this report may be used as an alternative to other surgical epiphysiodesis techniques.\nCLINICAL RELEVANCE: This technique may be useful for epiphysiodesis of small tubular bones of the hands and feet in humans.", "publicationTitle": "Clinical Orthopaedics and Related Research", "publisher": "", "place": "", "date": "2010-07", "volume": "468", "issue": "7", "section": "", "partNumber": "", "partTitle": "", "pages": "1943-1948", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clin Orthop Relat Res", "DOI": "10.1007/s11999-010-1286-8", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1528-1132", "archive": "", "archiveLocation": "", "shortTitle": "Percutaneous radiofrequency epiphysiodesis in a rabbit model", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 20306164\nPMCID: PMC2882017", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Catheter Ablation", "type": 1 }, { "tag": "Disease Models, Animal", "type": 1 }, { "tag": "Growth Plate", "type": 1 }, { "tag": "Leg Length Inequality", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Minimally Invasive Surgical Procedures", "type": 1 }, { "tag": "Orthopedic Procedures", "type": 1 }, { "tag": "Rabbits", "type": 1 }, { "tag": "Tibia", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:44:58Z", "dateModified": "2022-06-02T15:44:58Z" } }, { "key": "PBCCCJZA", "version": 4208, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/PBCCCJZA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/PBCCCJZA", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/LXP56KR2", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "PBCCCJZA", "version": 4208, "parentItem": "LXP56KR2", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:43:21Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/19700996", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:43:21Z", "dateModified": "2022-06-02T15:43:21Z" } }, { "key": "LXP56KR2", "version": 4208, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/LXP56KR2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/LXP56KR2", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Ghanem et al.", "parsedDate": "2009-09", "numChildren": 1 }, "data": { "key": "LXP56KR2", "version": 4208, "itemType": "journalArticle", "title": "Radiofrequency application to the growth plate in the rabbit: a new potential approach to epiphysiodesis", "creators": [ { "creatorType": "author", "firstName": "Ismat", "lastName": "Ghanem" }, { "creatorType": "author", "firstName": "Samer", "lastName": "El Hage" }, { "creatorType": "author", "firstName": "Michel", "lastName": "Diab" }, { "creatorType": "author", "firstName": "Elie", "lastName": "Saliba" }, { "creatorType": "author", "firstName": "Aline", "lastName": "Khazzaka" }, { "creatorType": "author", "firstName": "Georges", "lastName": "Aftimos" }, { "creatorType": "author", "firstName": "Fernand", "lastName": "Dagher" }, { "creatorType": "author", "firstName": "Khalil", "lastName": "Kharrat" } ], "abstractNote": "BACKGROUND: Radiofrequency energy is being used more and more frequently in orthopaedics, mainly in the treatment of bone tumors. We postulated that radiofrequency ablation may produce growth plate lesions similar to those observed in the bone and conducted this study to see whether radiofrequency may be used as a technique for producing epiphysiodesis.\nMETHODS: We randomized 60 8-week-old female New Zealand white rabbits into 3 groups. Group A was destined for a total epiphysiodesis at 60 degrees C, group B was destined for a total epiphysiodesis at 90 degrees C, and group C for a lateral hemiepiphysiodesis at 90 degrees C. Radiofrequency energy was delivered in 1 minute in all 3 groups. Using fluoroscopic imaging, radiofrequency was applied percutaneously to the left proximal tibial physis whereas the right growth plate received a sham procedure. A bicortical pin was used to evaluate the longitudinal growth rate at every monthly radiologic control, beginning 8 weeks after the procedure. Comparisons between the right and left side and between groups A and B were achieved using a paired t test. A histopathologic study was conducted in parallel to the radiographic study.\nRESULTS: In a radiograph at the 8-week point, pin migration was 4.74 mm on the left side compared with 9.72 mm on the right (P<0.0001), in group A. In group B, pin migration on the left was 1.37 mm compared with 5.49 mm on the right (P<0.0001). In group C, mean angular deviation was 11.6 degrees on the left compared with 1.9 degrees on the right (P=0.0001). These differences were maintained until the end of growth. Pathology specimens revealed cellular anarchy, loss of columnar stratification, and height of the physis on the left side, which occurred earlier and were more pronounced in group B than in group A. In group C, these changes involved only the lateral half of the left physis whereas its medial counterpart remained normal. There was no evidence of articular cartilage damage.\nCONCLUSIONS: This experimental study shows that radiofrequency can efficiently and rapidly achieve epiphysiodesis. It is one of many methods that can be used for this purpose. The development of new electrodes suitable for use on human growth plates and the elaboration of specific utilization protocols may lead to its use in children. Its simplicity and precision may lead to a quick and efficient growth arrest with little pain and postoperative disability in addition to reduced costs.\nCLINICAL RELEVANCE: Radiofrequency has proved to be effective in producing growth arrest in rabbits with no complications. Technical improvements and adaptations may allow its use for pediatric limb inequalities or angular deformities in the near future.", "publicationTitle": "Journal of Pediatric Orthopedics", "publisher": "", "place": "", "date": "2009-09", "volume": "29", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "629-635", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Pediatr Orthop", "DOI": "10.1097/BPO.0b013e3181b2bae7", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1539-2570", "archive": "", "archiveLocation": "", "shortTitle": "Radiofrequency application to the growth plate in the rabbit", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 19700996", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Catheter Ablation", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Fluoroscopy", "type": 1 }, { "tag": "Growth Plate", "type": 1 }, { "tag": "Orthopedic Procedures", "type": 1 }, { "tag": "Rabbits", "type": 1 }, { "tag": "Random Allocation", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:43:17Z", "dateModified": "2022-06-02T15:43:17Z" } }, { "key": "KX3HMF2V", "version": 4207, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/KX3HMF2V", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/KX3HMF2V", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/KBFTNPB9", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "KX3HMF2V", "version": 4207, "parentItem": "KBFTNPB9", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:41:43Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/2364612", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:41:43Z", "dateModified": "2022-06-02T15:41:43Z" } }, { "key": "KBFTNPB9", "version": 4207, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/KBFTNPB9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/KBFTNPB9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Rosen et al.", "parsedDate": "1990-07", "numChildren": 1 }, "data": { "key": "KBFTNPB9", "version": 4207, "itemType": "journalArticle", "title": "Epiphysiodesis by electrocautery in the rabbit and dog", "creators": [ { "creatorType": "author", "firstName": "M. A.", "lastName": "Rosen" }, { "creatorType": "author", "firstName": "K. J.", "lastName": "Beer" }, { "creatorType": "author", "firstName": "J. P.", "lastName": "Wiater" }, { "creatorType": "author", "firstName": "D. D.", "lastName": "Davidson" } ], "abstractNote": "Numerous experiments have demonstrated arrest of longitudinal bone growth by traumatizing the epiphyseal growth plate. Recently, promising studies have been performed using less invasive means to produce epiphysiodesis than the conventional surgical technique. The distal femoral physeal plate was cauterized in 20 rabbits and 17 dogs through an inserted needle and a standard operating room electrocautery machine. The result showed a progressive distal femoral length reduction without angular deformities in the experimental limb averaging 3 mm at two weeks to 11.6 mm at 20 weeks after the surgical procedure in the rabbit and 11.5 mm at 12 weeks in the dog. Histologic sections demonstrated thermal injury to the physis followed by a progressive narrowing and eventual resorption of the growth plate.", "publicationTitle": "Clinical Orthopaedics and Related Research", "publisher": "", "place": "", "date": "1990-07", "volume": "", "issue": "256", "section": "", "partNumber": "", "partTitle": "", "pages": "244-253", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clin Orthop Relat Res", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0009-921X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 2364612", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Dogs", "type": 1 }, { "tag": "Electrocoagulation", "type": 1 }, { "tag": "Femur", "type": 1 }, { "tag": "Growth Plate", "type": 1 }, { "tag": "Needles", "type": 1 }, { "tag": "Rabbits", "type": 1 }, { "tag": "Radiography", "type": 1 }, { "tag": "Time Factors", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:41:42Z", "dateModified": "2022-06-02T15:41:42Z" } }, { "key": "Q68DSNPJ", "version": 4206, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/Q68DSNPJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/Q68DSNPJ", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/6G39JA93", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "Q68DSNPJ", "version": 4206, "parentItem": "6G39JA93", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:40:48Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/6576145", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:40:48Z", "dateModified": "2022-06-02T15:40:48Z" } }, { "key": "6G39JA93", "version": 4206, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/6G39JA93", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/6G39JA93", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Eriksson and Albrektsson", "parsedDate": "1983-07", "numChildren": 1 }, "data": { "key": "6G39JA93", "version": 4206, "itemType": "journalArticle", "title": "Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit", "creators": [ { "creatorType": "author", "firstName": "A. R.", "lastName": "Eriksson" }, { "creatorType": "author", "firstName": "T.", "lastName": "Albrektsson" } ], "abstractNote": "", "publicationTitle": "The Journal of Prosthetic Dentistry", "publisher": "", "place": "", "date": "1983-07", "volume": "50", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "101-107", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Prosthet Dent", "DOI": "10.1016/0022-3913(83)90174-9", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0022-3913", "archive": "", "archiveLocation": "", "shortTitle": "Temperature threshold levels for heat-induced bone tissue injury", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 6576145", "tags": [ { "tag": "Adipose Tissue", "type": 1 }, { "tag": "Animals", "type": 1 }, { "tag": "Bone and Bones", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Hot Temperature", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Rabbits", "type": 1 }, { "tag": "Time Factors", "type": 1 }, { "tag": "Wound Healing", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:40:48Z", "dateModified": "2022-06-02T15:40:48Z" } }, { "key": "3R5RSBNM", "version": 4205, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/3R5RSBNM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/3R5RSBNM", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/35367/items/KDMPQDQW", "type": "application/json" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } } }, "data": { "key": "3R5RSBNM", "version": 4205, "parentItem": "KDMPQDQW", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2022-06-02T15:37:58Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/26500356", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2022-06-02T15:37:58Z", "dateModified": "2022-06-02T15:37:58Z" } }, { "key": "KDMPQDQW", "version": 4205, "library": { "type": "group", "id": 35367, "name": "Ablation Group", "links": { "alternate": { "href": "https://www.zotero.org/groups/ablation_group", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/35367/items/KDMPQDQW", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ablation_group/items/KDMPQDQW", "type": "text/html" } }, "meta": { "createdByUser": { "id": 326490, "username": "clbrace", "name": "Chris Brace", "links": { "alternate": { "href": "https://www.zotero.org/clbrace", "type": "text/html" } } }, "creatorSummary": "Murray and Azari", "parsedDate": "2015-09", "numChildren": 1 }, "data": { "key": "KDMPQDQW", "version": 4205, "itemType": "journalArticle", "title": "Leg length discrepancy and osteoarthritis in the knee, hip and lumbar spine", "creators": [ { "creatorType": "author", "firstName": "Kelvin J.", "lastName": "Murray" }, { "creatorType": "author", "firstName": "Michael F.", "lastName": "Azari" } ], "abstractNote": "Osteoarthritis (OA) is an extremely common condition that creates substantial personal and health care costs. An important recognised risk factor for OA is excessive or abnormal mechanical joint loading. Leg length discrepancy (LLD) is a common condition that results in uneven and excessive loading of not only knee joints but also hip joints and lumbar motion segments. Accurate imaging methods of LLD have made it possible to study the biomechanical effects of mild LLD (LLD of 20mm or less). This review examines the accuracy of these methods compared to clinical LLD measurements. It then examines the association between LLD and OA of the joints of the lower extremity. More importantly, it addresses the largely neglected association between LLD and degeneration of lumbar motion segments and the patterns of biomechanical changes that accompany LLD. We propose that mild LLD may be an important instigator or contributor to OA of the hip and lumbar spine, and that it deserves to be rigorously studied in order to decrease OA's burden of disease.", "publicationTitle": "The Journal of the Canadian Chiropractic Association", "publisher": "", "place": "", "date": "2015-09", "volume": "59", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "226-237", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Can Chiropr Assoc", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0008-3194", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "PMID: 26500356\nPMCID: PMC4593034", "tags": [ { "tag": "chiropractic", "type": 1 }, { "tag": "hip", "type": 1 }, { "tag": "knee", "type": 1 }, { "tag": "leg length discrepancy", "type": 1 }, { "tag": "lumbar spine", "type": 1 }, { "tag": "osteoarthritis", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2022-06-02T15:37:58Z", "dateModified": "2022-06-02T15:37:58Z" } } ]