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            "abstractNote": "Abstract Electronic cigarette consumption (‘vaping’) is marketed as an alternative to conventional tobacco smoking. Technically, a mixture of chemicals containing carrier liquids, flavors, and optionally nicotine is vaporized and inhaled. The present study aims at the determination of the release of volatile organic compounds (VOC) and (ultra)fine particles (FP/UFP) from an e-cigarette under near-to-real-use conditions in an 8-m3 emission test chamber. Furthermore, the inhaled mixture is analyzed in small chambers. An increase in FP/UFP and VOC could be determined after the use of the e-cigarette. Prominent components in the gas-phase are 1,2-propanediol, 1,2,3-propanetriol, diacetin, flavorings, and traces of nicotine. As a consequence, ‘passive vaping’ must be expected from the consumption of e-cigarettes. Furthermore, the inhaled aerosol undergoes changes in the human lung that is assumed to be attributed to deposition and evaporation. Practical Implications The consumption of e-cigarettes marks a new source for chemical and aerosol exposure in the indoor environment. To evaluate the impact of e-cigarettes on indoor air quality and to estimate the possible effect of passive vaping, information about the chemical characteristics of the released vapor is needed.",
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                    "lastName": "Tierney"
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                    "lastName": "Vansickel"
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                    "firstName": "Michael F.",
                    "lastName": "Weaver"
                },
                {
                    "creatorType": "author",
                    "firstName": "Thomas",
                    "lastName": "Eissenberg"
                }
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            "abstractNote": "Aims  To provide an initial abuse liability assessment of an electronic cigarette (EC) in current tobacco cigarette smokers. Design  The first of four within-subject sessions was an EC sampling session that involved six, 10-puff bouts (30 seconds inter-puff interval), each bout separated by 30 minutes. In the remaining three sessions participants made choices between 10 EC puffs and varying amounts of money, 10 EC puffs and a varying number of own brand cigarette (OB) puffs, or 10 OB puffs and varying amounts of money using the multiple-choice procedure (MCP). The MCP was completed six times at 30-minute intervals, and one choice was reinforced randomly at each trial. Setting  Clinical laboratory. Participants  Twenty current tobacco cigarette smokers. Measurements  Sampling session outcome measures included plasma nicotine, cardiovascular response and subjective effects. Choice session outcome was the cross-over value on the MCP. Findings  EC use resulted in significant nicotine delivery, tobacco abstinence symptom suppression and increased product acceptability ratings. On the MCP, participants chose to receive 10 EC puffs over an average of $1.06 or three OB puffs and chose 10 OB puffs over an average of $1.50 (P < 0.003). Conclusions   Electronic cigarettes can deliver clinically significant amounts of nicotine and reduce cigarette abstinence symptoms and appear to have lower potential for abuse relative to traditional tobacco cigarettes, at least under certain laboratory conditions.",
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            "abstractNote": "Two contrasting reviews (authored by Abrams et al. and Glanz & Bareham) in this volume have reached opposing conclusions on the effects of electronic cigarettes in a debate that is dividing the scientific and professional communities that have devoted careers to controlling the manufacture, advertising, sale, and use of combustible cigarettes. The research on the types, degree, and extent of harm from e-cigarettes is far from complete and, together with trends in teenage smoking and vaping, has raised new questions and prospects about the potential benefits that the new electronic products offer smokers of combustible cigarettes in quitting or at least cutting back on the known risks associated with the traditional forms of smoking. The rapidly morphing forms, constituents, promotions, and uses of the electronic varieties of the new nicotine delivery products (in this case electronic cigarettes) make research on their biological and behavioral effects moving targets. The two sides of this argument have produced a global divide on policy strategies. Expected final online publication date for the Annual Review of Public Health Volume 39 is April 1, 2018. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.",
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            "abstractNote": "Since e-cigarettes appeared in the mid-2000s, some practitioners, researchers, and policy makers have embraced them as a safer alternative to conventional cigarettes and an effective way to stop smoking. While e-cigarettes deliver lower levels of carcinogens than do conventional cigarettes, they still expose users to high levels of ultrafine particles and other toxins that may substantially increase cardiovascular and noncancer lung disease risks, which account for more than half of all smoking-caused deaths, at rates similar to conventional cigarettes. Moreover, rather than stimulating smokers to switch from conventional cigarettes to less dangerous e-cigarettes or quitting altogether, e-cigarettes are reducing smoking cessation rates and expanding the nicotine market by attracting youth.;",
            "publicationTitle": "Annual Review Of Public Health",
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            "pages": "215-235",
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            "tags": [
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                    "firstName": "Nathan K.",
                    "lastName": "Cobb"
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                    "lastName": "Abrams"
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            ],
            "abstractNote": "The FDA intends to regulate e-cigarettes as tobacco products, since the courts blocked it from treating them as drug-delivery devices. Until the FDA asserts its new authority over tobacco, concentrated nicotine products may be sold to consumers, raising safety concerns.",
            "publicationTitle": "The New England Journal of Medicine",
            "publisher": "",
            "place": "",
            "date": "Jul 21, 2011",
            "volume": "365",
            "issue": "3",
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            "partNumber": "",
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            "pages": "193-5",
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            "url": "http://libproxy.library.unt.edu:2095/docview/878644195",
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            "shortTitle": "E-Cigarette or Drug-Delivery Device?",
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            "libraryCatalog": "ProQuest",
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            "rights": "Copyright © 2011 Massachusetts Medical Society. All rights reserved.",
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            "tags": [
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                    "tag": "Cigarettes"
                },
                {
                    "tag": "Cocaine"
                },
                {
                    "tag": "Drug dosages"
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                {
                    "tag": "Federal regulation"
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            "creatorSummary": "Primack et al.",
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            "itemType": "journalArticle",
            "title": "Progression to Traditional Cigarette Smoking After Electronic Cigarette Use Among US Adolescents and Young Adults.",
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                    "firstName": "Brian A",
                    "lastName": "Primack"
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                {
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                    "firstName": "Samir",
                    "lastName": "Soneji"
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                {
                    "creatorType": "author",
                    "firstName": "Michael",
                    "lastName": "Stoolmiller"
                },
                {
                    "creatorType": "author",
                    "firstName": "Michael J",
                    "lastName": "Fine"
                },
                {
                    "creatorType": "author",
                    "firstName": "James D",
                    "lastName": "Sargent"
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            ],
            "abstractNote": "Importance: Electronic cigarettes (e-cigarettes) may help smokers reduce the use of traditional combustible cigarettes. However, adolescents and young adults who have never smoked traditional cigarettes are now using e-cigarettes, and these individuals may be at risk for subsequent progression to traditional cigarette smoking.; Objective: To determine whether baseline use of e-cigarettes among nonsmoking and nonsusceptible adolescents and young adults is associated with subsequent progression along an established trajectory to traditional cigarette smoking.; Design, Setting, and Participants: In this longitudinal cohort study, a national US sample of 694 participants aged 16 to 26 years who were never cigarette smokers and were attitudinally nonsusceptible to smoking cigarettes completed baseline surveys from October 1, 2012, to May 1, 2014, regarding smoking in 2012-2013. They were reassessed 1 year later. Analysis was conducted from July 1, 2014, to March 1, 2015. Multinomial logistic regression was used to assess the independent association between baseline e-cigarette use and cigarette smoking, controlling for sex, age, race/ethnicity, maternal educational level, sensation-seeking tendency, parental cigarette smoking, and cigarette smoking among friends. Sensitivity analyses were performed, with varying approaches to missing data and recanting.; Exposures: Use of e-cigarettes at baseline.; Main Outcomes and Measures: Progression to cigarette smoking, defined using 3 specific states along a trajectory: nonsusceptible nonsmokers, susceptible nonsmokers, and smokers. Individuals who could not rule out smoking in the future were defined as susceptible.; Results: Among the 694 respondents, 374 (53.9%) were female and 531 (76.5%) were non-Hispanic white. At baseline, 16 participants (2.3%) used e-cigarettes. Over the 1-year follow-up, 11 of 16 e-cigarette users and 128 of 678 of those who had not used e-cigarettes (18.9%) progressed toward cigarette smoking. In the primary fully adjusted models, baseline e-cigarette use was independently associated with progression to smoking (adjusted odds ratio [AOR], 8.3; 95% CI, 1.2-58.6) and to susceptibility among nonsmokers (AOR, 8.5; 95% CI, 1.3-57.2). Sensitivity analyses showed consistent results in the level of significance and slightly larger magnitude of AORs.; Conclusions and Relevance: In this national sample of US adolescents and young adults, use of e-cigarettes at baseline was associated with progression to traditional cigarette smoking. These findings support regulations to limit sales and decrease the appeal of e-cigarettes to adolescents and young adults.;",
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