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This review examines the current evidence regarding the impact of this conversion on healthcare resource utilization and costs. Simulated decision models represent the majority of the research conducted in this area and appear to suggest that the availability of OTC loratadine reduces patient cost sharing, health-plan costs, and motor-vehicle accidents, and also improves work-related productivity. Other empirical research examining the policies adopted by health plans in response to the availability of OTC loratadine suggests that restricting access to prescription SGAs by placing these products in the third tier, thereby encouraging patients to purchase OTC loratadine, results in the greatest reduction in pharmacy-related costs for SGAs. However, early evaluations of such policies using health-plan data for the year 2003 show mixed results. Initial conclusions suggest that OTC loratadine has the potential to function as a safer treatment alternative to the sedating first-generation antihistamines in the treatment of allergic rhinitis. What is unclear is the impact of OTC loratadine on overall healthcare costs, as patients may choose the convenience of an OTC alternative to manage their allergic rhinitis in lieu of physician-supervised care. Further research is needed to examine if patients are unable to correctly diagnose their allergic rhinitis symptoms, which could potentially mask other chronic conditions and result in increased healthcare utilization and associated expenditures.", "publicationTitle": "Disease Management & Health Outcomes", "publisher": "", "place": "", "date": "April 2006", "volume": "14", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "69-74", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Disease Management & Health Outcomes", "DOI": "", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=rzh&AN=2009189995&site=ehost-live", "accessDate": "2015-05-11T21:46:24Z", "PMID": "", "PMCID": "", "ISSN": "1173-8790", "archive": "", "archiveLocation": "", "shortTitle": "Prescription to over-the-counter switch of second-generation antihistamines (loratadine)", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Drugs, Non-Prescription -- Administration and Dosage", "type": 1 }, { "tag": "Drugs, Non-Prescription -- Economics", "type": 1 }, { "tag": "Health Resource Utilization", "type": 1 }, { "tag": "Loratadine -- Administration and Dosage", "type": 1 }, { "tag": "Loratadine -- Economics", "type": 1 }, { "tag": "Patient Attitudes", "type": 1 }, { "tag": "Rhinitis, Allergic, Seasonal -- Drug Therapy", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2015-05-11T21:46:24Z", "dateModified": "2015-05-11T21:46:24Z" } }, { "key": "TSFFKJRX", "version": 55, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/TSFFKJRX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/TSFFKJRX", "type": 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The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment Study", "creators": [ { "creatorType": "author", "firstName": "Eric P.", "lastName": "Brass" }, { "creatorType": "author", "firstName": "Theodore", "lastName": "Vassil" }, { "creatorType": "author", "firstName": "Amy", "lastName": "Replogle" }, { "creatorType": "author", "firstName": "Peggy", "lastName": "Hwang" }, { "creatorType": "author", "firstName": "Steven", "lastName": "Rusche" }, { "creatorType": "author", "firstName": "Saul", "lastName": "Shiffman" }, { "creatorType": "author", "firstName": "Jeffrey G.", "lastName": "Levine" } ], "abstractNote": "Access to over-the-counter (OTC) statins has the potential to improve public health by reducing cardiovascular events. The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment (SELECT) Study was designed to assess consumers' ability to self-select for treatment with lovastatin in an unsupervised setting. Subjects examined proposed OTC lovastatin cartons with labels that detailed an algorithm for self-selection based on age, lipid profile, and cardiovascular risk factors. Subjects viewed a carton with either a low-density lipoprotein cholesterol–based self-selection algorithm or one based on total cholesterol. Labels also contained warnings against use based on health conditions that might increase the risk of adverse events. Subjects were asked if the drug was appropriate for their use (self-assessment) and whether they would like to purchase the drug (purchase decision). A total of 1,326 consumers provided self-assessment decisions. After viewing the low-density lipoprotein cholesterol–based label, 82%, 36%, and 82% of those who self-assessed that the drug was appropriate for their use were correct with respect to the age, lipid, and risk-factor criteria, respectively. Corresponding numbers for the total cholesterol algorithm were 85%, 50% and 75%. Almost 90% of women aged <55 years who evaluated the drug indicated the drug was not right for them, and women in this age group made up only 9% of the total group of subjects who believed the drug was appropriate for their use. The label was also effective in discouraging use by women who were or may become pregnant, consumers with liver disease, and those with potential drug interactions. In conclusion, SELECT showed that consumers could use an OTC drug label in an unsupervised setting to appropriately self-select for self-management of their cholesterol with lovastatin.", "publicationTitle": "The American Journal of Cardiology", "publisher": "", "place": "", "date": "May 15, 2008", "volume": "101", "issue": "10", "section": "", "partNumber": "", "partTitle": "", "pages": "1448-1455", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "The American Journal of Cardiology", "DOI": "10.1016/j.amjcard.2008.01.020", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0002914908001586", "accessDate": "2015-05-07T15:57:39Z", "PMID": "", "PMCID": "", "ISSN": "0002-9149", "archive": "", "archiveLocation": "", "shortTitle": "Can Consumers Self-Select for Appropriate Use of an Over-the-Counter Statin?", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2015-05-07T15:58:08Z", "dateModified": "2015-05-07T15:58:08Z" } }, { "key": "TVCHSBDC", "version": 50, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/TVCHSBDC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/TVCHSBDC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2345188, "username": "EggrollEric", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/eggrolleric", "type": "text/html" } } }, "creatorSummary": "Ali and Topaler", "numChildren": 1 }, "data": { "key": "TVCHSBDC", "version": 50, "itemType": "journalArticle", "title": "How removing prescription drugs from reimbursement lists increases the pharmaceutical expenditures for alternatives - Springer", "creators": [ { "creatorType": "author", "firstName": "Özden Gür", "lastName": "Ali" }, { "creatorType": "author", "firstName": "Başak", "lastName": "Topaler" } ], "abstractNote": "", "publicationTitle": "", "publisher": "", "place": "", "date": "", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1007/s10198-010-0270-2", "citationKey": "", "url": "http://link.springer.com/article/10.1007/s10198-010-0270-2/fulltext.html", "accessDate": "2015-04-16T16:01:16Z", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "link.springer.com", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2015-04-16T16:01:16Z", "dateModified": "2015-04-16T16:02:32Z" } }, { "key": "P25TB7QF", "version": 46, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/P25TB7QF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/P25TB7QF", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/TVCHSBDC", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2345188, "username": "EggrollEric", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/eggrolleric", "type": "text/html" } } } }, "data": { "key": "P25TB7QF", "version": 46, "parentItem": "TVCHSBDC", "itemType": "attachment", "linkMode": "linked_url", "title": "Snapshot", "accessDate": "2015-04-16T16:01:16Z", "url": "http://link.springer.com/article/10.1007/s10198-010-0270-2/fulltext.html", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-04-16T16:01:16Z", "dateModified": "2015-04-16T16:01:16Z" } }, { "key": "QFUBZZZN", "version": 41, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/QFUBZZZN", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/QFUBZZZN", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/QAGD7TX6", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } } }, "data": { "key": "QFUBZZZN", "version": 41, "parentItem": "QAGD7TX6", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed Central Link", "accessDate": "2015-03-01T18:23:26Z", "url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350384/", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T22:54:11Z", "dateModified": "2015-03-03T22:54:11Z" } }, { "key": "QAGD7TX6", "version": 41, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/QAGD7TX6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/QAGD7TX6", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } }, "creatorSummary": "Blenkinsopp and Bradley", "parsedDate": "1996-03-09", "numChildren": 1 }, "data": { "key": "QAGD7TX6", "version": 41, "itemType": "journalArticle", "title": "Patients, society, and the increase in self medication.", "creators": [ { "creatorType": "author", "firstName": "A.", "lastName": "Blenkinsopp" }, { "creatorType": "author", "firstName": "C.", "lastName": "Bradley" } ], "abstractNote": "Self medication with over the counter medicines has long been a feature of the lay health system. With the reclassification of certain drugs, the public can buy preparations that were previously available only prescription. Sales of over the counter medicines are now equivalent to a third of the NHS drugs bill; governments throughout the world see self medication as a way of shifting some of the cost of health care onto consumers. The trend towards increased self care and with it the increasing empowerment of patients has many potential benefits; collaboration between doctors and pharmacists will be critical.", "publicationTitle": "BMJ : British Medical Journal", "publisher": "", "place": "", "date": "1996-3-9", "volume": "312", "issue": "7031", "section": "", "partNumber": "", "partTitle": "", "pages": "629-632", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "BMJ", "DOI": "", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350384/", "accessDate": "2015-03-01T18:23:26Z", "PMID": "", "PMCID": "", "ISSN": "0959-8138", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "PubMed Central", "callNumber": "", "rights": "", "extra": "PMID: 8595343\nPMCID: PMC2350384", "tags": [], "collections": [ "62X3RXTN" ], "relations": {}, "dateAdded": "2015-03-03T22:54:11Z", "dateModified": "2015-03-03T22:54:11Z" } }, { "key": "J8M9BGA4", "version": 41, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/J8M9BGA4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/J8M9BGA4", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/5WJ54WUB", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } } }, "data": { "key": "J8M9BGA4", "version": 41, "parentItem": "5WJ54WUB", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2015-02-26T17:12:44Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/8608296", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T22:54:09Z", "dateModified": "2015-03-03T22:54:09Z" } }, { "key": "5WJ54WUB", "version": 41, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/5WJ54WUB", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/5WJ54WUB", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } }, "creatorSummary": "Bradley and Blenkinsopp", "parsedDate": "1996-03-30", "numChildren": 1 }, "data": { "key": "5WJ54WUB", "version": 41, "itemType": "journalArticle", "title": "Over the Counter Drugs: The future for self medication", "creators": [ { "creatorType": "author", "firstName": "Colin", "lastName": "Bradley" }, { "creatorType": "author", "firstName": "Alison", "lastName": "Blenkinsopp" } ], "abstractNote": "The increasing trend towards deregulation of more medicines to over the counter status has implications for the primary health care team as well as for consumers and patients. Better information for patients could improve the safety of over the counter medicines, but better systems need to be devised for reporting adverse reactions. “Collaborative care” could bring financial benefits. Doctors, nurses, and pharmacists need to discuss how they will respond to self medication practices, and ways of rewarding pharmacists for advising patients need to be found. Improved communication between doctors and pharmacists and the involvement of nurses could bring health care professionals into a new and more constructive interaction with each other and with the patient—or the changes required could split the professions as they each try to keep control of medicines.\n\nPredicting the future is always risky, but current trends and the stated intentions of policy makers and stakeholders are often helpful. As we argued in the first article in this series, the factors promoting greater availability and use of over the counter medicines far outweigh the inhibitors.1 The uncertainty is therefore how far this trend will go and how health care professionals and consumers will respond.\n\nMore drugs were changed from prescription only medicines (POM) to pharmacy (P) medicines in the past two years than over the previous decade.1 Furthermore, the range now encompasses drugs which have, on prescription, been used for potentially more serious and longer term conditions.2 Some of the more recently deregulated medicines (H2 antagonists, for example) may not seem to doctors to be natural choices for over the counter use. However, formulations, dosages, and licensed indications for drugs that become available over the counter are not necessarily the same as those which pertain to its use as a prescription only preparation.\n\nThe …", "publicationTitle": "BMJ", "publisher": "", "place": "", "date": "1996/03/30", "volume": "312", "issue": "7034", "section": "", "partNumber": "", "partTitle": "", "pages": "835-837", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1136/bmj.312.7034.835", "citationKey": "", "url": "http://www.bmj.com/content/312/7034/835", "accessDate": "2015-02-26T17:12:44Z", "PMID": "", "PMCID": "", "ISSN": "0959-8138, 1468-5833", "archive": "", "archiveLocation": "", "shortTitle": "Over the Counter Drugs", "language": "en", "libraryCatalog": "www.bmj.com", "callNumber": "", "rights": "© 1996 BMJ Publishing Group Ltd.", "extra": "PMID: 8608296", "tags": [], "collections": [ "62X3RXTN" ], "relations": {}, "dateAdded": "2015-03-03T22:54:09Z", "dateModified": "2015-03-03T22:54:09Z" } }, { "key": "D2JIQGJ3", "version": 40, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/D2JIQGJ3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/D2JIQGJ3", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/2PS2Z5J6", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } } }, "data": { "key": "D2JIQGJ3", "version": 40, "parentItem": "2PS2Z5J6", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2015-03-01T18:16:31Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/18178702", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T22:54:03Z", "dateModified": "2015-03-03T22:54:03Z" } }, { "key": "2PS2Z5J6", "version": 40, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/2PS2Z5J6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/2PS2Z5J6", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2349042, "username": "egb1996", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/egb1996", "type": "text/html" } } }, "creatorSummary": "Lessenger and Feinberg", "parsedDate": "2008-01-01", "numChildren": 1 }, "data": { "key": "2PS2Z5J6", "version": 40, "itemType": "journalArticle", "title": "Abuse of Prescription and Over-the-Counter Medications", "creators": [ { "creatorType": "author", "firstName": "James E.", "lastName": "Lessenger" }, { "creatorType": "author", "firstName": "Steven D.", "lastName": "Feinberg" } ], "abstractNote": "The nonmedical use of prescription or over-the-counter (OTC) medications implies that the user is using them for reasons other than those indicated in the prescribing literature or on the box label. The abuse of these medications is a national issue.\nIntentional drug abuse of prescribed and OTC medicines has climbed steadily. Data from the 2005 National Survey on Drug Use and Health demonstrated that 6.4 million (2.6%) people aged 12 or older had used prescription drugs for nonmedical reasons during the past month. Of these, 4.7 million used pain relievers, 1.8 million used tranquilizers, and 1.1 million used stimulants. The nonmedical use of prescription drugs in the past month among young adults aged 18 to 25 increased from 5.4% in 2002 to 6.3% in 2005, primarily because of an increase in the abusive use of pain relievers.\nPhysicians need to watch for prescription and OTC medication abuse. Treatment strategies include (1) inquiring about prescription, OTC, and herbal drug use at the initial examination (even though many individuals are drug-abuse savvy, some are naïve and do not realize that OTC medications can be problematic); (2) inquiring about drug use during office visits; (3) providing disposal containers that patients can use to dispose of their unused or unneeded prescription or OTC medications; (4) treating pain aggressively and appropriately; (5) practicing careful record keeping of prescription refills and controls over prescription blanks; (6) referring patients who are addicted to medications to 12-step programs such as Alcoholic Anonymous, Narcotics Anonymous, and Pills Anonymous; and (7) considering detoxification.", "publicationTitle": "The Journal of the American Board of Family Medicine", "publisher": "", "place": "", "date": "01/01/2008", "volume": "21", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "45-54", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Am Board Fam Med", "DOI": "10.3122/jabfm.2008.01.070071", "citationKey": "", "url": "http://www.jabfm.org/content/21/1/45", "accessDate": "2015-03-01T18:16:31Z", "PMID": "", "PMCID": "", "ISSN": "1557-2625, 1558-7118", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "en", "libraryCatalog": "www.jabfm.org", "callNumber": "", "rights": "", "extra": "PMID: 18178702", "tags": [], "collections": [ "62X3RXTN" ], "relations": {}, "dateAdded": "2015-03-03T22:54:03Z", "dateModified": "2015-03-03T22:54:03Z" } }, { "key": "8F4UH9KE", "version": 37, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/8F4UH9KE", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/8F4UH9KE", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/6UK38JCI", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } } }, "data": { "key": "8F4UH9KE", "version": 37, "parentItem": "6UK38JCI", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Full Text PDF", "accessDate": "2015-03-03T01:50:44Z", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800167/pdf?md5=d9f814d578d8bad55869d7f804eaeb01&pid=1-s2.0-S0149291898800167-main.pdf", "note": "", "contentType": "application/pdf", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T01:50:44Z", "dateModified": "2015-03-03T01:50:44Z" } }, { "key": "6UK38JCI", "version": 37, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/6UK38JCI", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/6UK38JCI", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } }, "creatorSummary": "Byrns", "parsedDate": "1998", "numChildren": 2 }, "data": { "key": "6UK38JCI", "version": 37, "itemType": "journalArticle", "title": "Prescription to over-the-counter switches: the physician perspective", "creators": [ { "creatorType": "author", "firstName": "Patricia J.", "lastName": "Byrns" } ], "abstractNote": "Changes in a drug's availability from prescription only to over-the-counter (OTC) status is of concern to physicians from both public health and individual patient perspectives. While acknowledging the potential benefits of these switches, the author notes important caveats, including the need for scientifically derived pediatric dosages; information in the medical record regarding OTC use that allows cohesive monitoring; clarity and precision in labeling for consumers; and continued coverage of such drugs for medically indigent patient populations. Current actions by physician organizations are noted.", "publicationTitle": "Clinical Therapeutics", "publisher": "", "place": "", "date": "1998", "volume": "20, Supplement 3", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "C118-C123", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clinical Therapeutics", "DOI": "10.1016/S0149-2918(98)80016-7", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800167", "accessDate": "2015-03-03T01:50:44Z", "PMID": "", "PMCID": "", "ISSN": "0149-2918", "archive": "", "archiveLocation": "", "shortTitle": "Prescription to over-the-counter switches", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "OTC", "type": 1 }, { "tag": "benefit coverage", "type": 1 }, { "tag": "drug labeling", "type": 1 }, { "tag": "pediatric dosages", "type": 1 } ], "collections": [ "XFC5U9DM" ], "relations": {}, "dateAdded": "2015-03-03T01:50:44Z", "dateModified": "2015-03-03T01:50:44Z" } }, { "key": "ZVCE7PV5", "version": 37, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/ZVCE7PV5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/ZVCE7PV5", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/6UK38JCI", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } } }, "data": { "key": "ZVCE7PV5", "version": 37, "parentItem": "6UK38JCI", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Snapshot", "accessDate": "2015-03-03T01:50:44Z", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800167#", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T01:50:44Z", "dateModified": "2015-03-03T01:50:44Z" } }, { "key": "VZE34FPQ", "version": 36, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/VZE34FPQ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/VZE34FPQ", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/X5KCF56W", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } } }, "data": { "key": "VZE34FPQ", "version": 36, "parentItem": "X5KCF56W", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Full Text PDF", "accessDate": "2015-03-03T01:15:04Z", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800179/pdf?md5=430f2c098a8d54b7ce85336ae21e6e89&pid=1-s2.0-S0149291898800179-main.pdf", "note": "", "contentType": "application/pdf", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T01:15:04Z", "dateModified": "2015-03-03T01:15:04Z" } }, { "key": "X5KCF56W", "version": 36, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/X5KCF56W", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/X5KCF56W", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } }, "creatorSummary": "Schulke", "parsedDate": "1998", "numChildren": 2 }, "data": { "key": "X5KCF56W", "version": 36, "itemType": "journalArticle", "title": "American pharmaceutical association review of literature on prescription to over-the-counter drug switches", "creators": [ { "creatorType": "author", "firstName": "David G.", "lastName": "Schulke" } ], "abstractNote": "Research was conducted by staff of the American Pharmaceutical Association (APhA), the national professional society of pharmacists, to inform the APhA policy process. Findings indicate that many consumers view products that were switched from prescription to over-the-counter (OTC) status as being more effective than products that have not previously been designated as prescription drugs, and they prefer to purchase switched products. Consumer purchases of switched products replace utilization of prescription drugs, physician visits, and laboratory services, but no data were found concerning increased utilization that may eventually result from foregone or delayed medical attention. Evidence exists that many comparatively well-informed consumers are knowingly using these products in a manner inconsistent with their labeling, and are using complementary and alternative medications for which labeling is uninformative in lieu of either prescription or OTC products. A need exists for more and better-quality pharmaceutical care services from pharmacists to support informed self-care decision making by consumers.", "publicationTitle": "Clinical Therapeutics", "publisher": "", "place": "", "date": "1998", "volume": "20, Supplement 3", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "C124-C133", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clinical Therapeutics", "DOI": "10.1016/S0149-2918(98)80017-9", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800179", "accessDate": "2015-03-03T01:15:04Z", "PMID": "", "PMCID": "", "ISSN": "0149-2918", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "American Pharmaceutical Association", "type": 1 }, { "tag": "Rx-to-OTC switch", "type": 1 }, { "tag": "alternative medication", "type": 1 }, { "tag": "complementary medication", "type": 1 }, { "tag": "pharmacy class", "type": 1 }, { "tag": "self-care", "type": 1 } ], "collections": [ "XFC5U9DM" ], "relations": {}, "dateAdded": "2015-03-03T01:15:04Z", "dateModified": "2015-03-03T01:15:04Z" } }, { "key": "74AEWU6Q", "version": 36, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/74AEWU6Q", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/74AEWU6Q", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/X5KCF56W", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2355971, "username": "monilghodasra", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/monilghodasra", "type": "text/html" } } } }, "data": { "key": "74AEWU6Q", "version": 36, "parentItem": "X5KCF56W", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Snapshot", "accessDate": "2015-03-03T01:15:04Z", "url": "http://www.sciencedirect.com/science/article/pii/S0149291898800179#", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T01:15:04Z", "dateModified": "2015-03-03T01:15:04Z" } }, { "key": "WRKMM4RZ", "version": 35, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/WRKMM4RZ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/WRKMM4RZ", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/332014/items/RFXEZUAH", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2355926, "username": "PJ25n", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/pj25n", "type": "text/html" } } } }, "data": { "key": "WRKMM4RZ", "version": 35, "parentItem": "RFXEZUAH", "itemType": "attachment", "linkMode": "linked_url", "title": "EBSCO Full Text", "accessDate": "2015-03-03T01:02:16Z", "url": "http://content.ebscohost.com/ContentServer.asp?T=P&P=AN&K=92012863&S=R&D=aph&EbscoContent=dGJyMMvl7ESeprA4y9fwOLCmr02eqK5Srqe4SrOWxWXS&ContentCustomer=dGJyMPPj34r34ux8uePfgeyx44Dt6fIA", "note": "", "contentType": "application/pdf", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-03-03T01:02:16Z", "dateModified": "2015-03-03T01:02:16Z" } }, { "key": "RFXEZUAH", "version": 35, "library": { "type": "group", "id": 332014, "name": "EggrollErupts", "links": { "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/332014/items/RFXEZUAH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/eggrollerupts/items/RFXEZUAH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2355926, "username": "PJ25n", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/pj25n", "type": "text/html" } } }, "creatorSummary": "Howard et al.", "parsedDate": "2013-12", "numChildren": 1 }, "data": { "key": "RFXEZUAH", "version": 35, "itemType": "journalArticle", "title": "Physician Attitudes Toward Over the Counter Availability for Oral Contraceptives", "creators": [ { "creatorType": "author", "firstName": "David L.", "lastName": "Howard" }, { "creatorType": "author", "firstName": "Jeffrey", "lastName": "Wall" }, { "creatorType": "author", "firstName": "Julie L.", "lastName": "Strickland" } ], "abstractNote": "To assess physician attitude towards making oral contraceptives available over the counter in the United States (US). We assessed physician attitudes towards a transition from prescription only to over-the-counter availability (rx-OTC) for oral contraceptive pills by disseminating an electronic survey directed primarily to residents training in Obstetrics and Gynecology (OBGYN) and Family Practice in the US. An overwhelming majority of 638 respondents (71 %) were against an rx-OTC switch for combined oral contraceptives and among this subset of respondents the primary concern was safety (92.3 %). Overall, respondents were evenly divided on the issue of an rx-OTC switch for progestin-only-pills but of those who opposed, 73.2 % cited safety as their primary concern. For progestin-only-pills female respondents were more likely to support OTC availability. Most OBGYN and Family Practice residents opposed to OTC availability for oral contraceptives cite safety as their primary concern. Considering the abundant evidence as to the overall safety of oral contraceptives, especially progestin-only-pills, there appears to be a knowledge deficit among OBGYN and Family Practice residents regarding the safety of oral contraceptives.", "publicationTitle": "Maternal & Child Health Journal", "publisher": "", "place": "", "date": "December 2013", "volume": "17", "issue": "10", "section": "", "partNumber": "", "partTitle": "", "pages": "1737-1743", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Maternal & Child Health Journal", "DOI": "10.1007/s10995-012-1185-6", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=92012863&login.asp&site=ehost-live", "accessDate": "2015-03-03T01:02:16Z", "PMID": "", "PMCID": "", "ISSN": "10927875", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "CHI-squared test", "type": 1 }, { "tag": "CONFIDENCE intervals", "type": 1 }, { "tag": "MISSOURI", "type": 1 }, { "tag": "NONPRESCRIPTION drugs", "type": 1 }, { "tag": "OBGYN resident", "type": 1 }, { "tag": "ORAL contraceptives", "type": 1 }, { "tag": "PHYSICIANS -- Attitudes", "type": 1 }, { "tag": "QUESTIONNAIRES", "type": 1 }, { "tag": "RESEARCH -- Finance", "type": 1 }, { "tag": "Rx-OTC", "type": 1 }, { "tag": "over-the-counter", "type": 1 } ], "collections": [ "XFC5U9DM" ], "relations": {}, "dateAdded": "2015-03-03T01:02:16Z", "dateModified": "2015-03-03T01:02:16Z" } } ]