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J.", "lastName": "Grimes" } ], "abstractNote": "1. Some effects of sodium salicylate upon anaerobic glycolysis have been studied in normal human erythrocytes incubated for up to 6 h at 37 degrees C in autologous sera. 2. Both glucose consumption and lactate production were stimulated by concentrations of salicylate up to 60 mmol/l but at the highest concentration used (90 mmol/l) an initial stimulus was followed by inhibition of glycolysis. 3. Losses occurred of adenosine 5'-triphosphate (ATP), adenosine 5'-diphosphate (ADP) and adenosine 5'-phosphate(AMP)at higher concentrations of salicylate and there was a concomitant increase of inorganic phosphate. 4. Other phosphate esters underwent concentration changes at higher concentrations of salicylate that reflected inadequate concentrations of ATP for glycolysis. 5. The rates of sodium efflux from, and potassium influx into, erythrocytes were unaffected by the presence of salicylate at concentrations sufficient to stimulate glycolysis.", "publicationTitle": "Clinical Science and Molecular Medicine", "publisher": "", "place": "", "date": "Nov 1975", "volume": "49", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "375-384", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clin Sci Mol Med", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "170", "PMCID": "", "ISSN": "0301-0538", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adenosine Diphosphate", "type": 1 }, { "tag": "Adenosine Monophosphate", "type": 1 }, { "tag": "Adenosine Triphosphate", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Dose-Response Relationship, Drug", "type": 1 }, { "tag": "Erythrocytes", "type": 1 }, { "tag": "Glycolysis", "type": 1 }, { "tag": "Hematocrit", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Hydrogen-Ion Concentration", "type": 1 }, { "tag": "In Vitro Techniques", "type": 1 }, { "tag": "Lactates", "type": 1 }, { "tag": "Phosphates", "type": 1 }, { "tag": "Potassium", "type": 1 }, { "tag": "Pyruvates", "type": 1 }, { "tag": "Sodium", "type": 1 }, { "tag": "Sodium Salicylate", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2016-07-15T18:39:03Z", "dateModified": "2016-07-15T18:39:03Z" } }, { "key": "PTPBFJVB", "version": 155, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/PTPBFJVB", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/PTPBFJVB", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/324191/items/25825S32", "type": "application/json" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } } }, "data": { "key": "PTPBFJVB", "version": 155, "parentItem": "25825S32", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2016-07-15T18:39:03Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/170", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2016-07-15T18:39:03Z", "dateModified": "2016-07-15T18:39:03Z" } }, { "key": "8R9HUKV2", "version": 169, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/8R9HUKV2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/8R9HUKV2", "type": "text/html" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } }, "lastModifiedByUser": { "id": 1523048, "username": "Christian Flachsland", "name": "Christian Flachsland", "links": { "alternate": { "href": "https://www.zotero.org/christian_flachsland", "type": "text/html" } } }, "creatorSummary": "Nitta and Yoneyama", "parsedDate": "1975-10", "numChildren": 1 }, "data": { "key": "8R9HUKV2", "version": 169, "itemType": "journalArticle", "title": "Polymer concentration dependence of the helix to random coil transition of a charged polypeptide in aqueous salt solution", "creators": [ { "creatorType": "author", "firstName": "K.", "lastName": "Nitta" }, { "creatorType": "author", "firstName": "M.", "lastName": "Yoneyama" } ], "abstractNote": "The helix to coil transition of poly(L-glutamic acid) was investigated in 0.05 and 0.005 M aqueous potassium chloride solutions by use of potentiometric titration and circular dichroism measurement. Polymer concentration dependence of the transition was observed in the range from 0.006 to 0.04 monomol/e in 0.005 M KG1 solution. The polymer concentration dependence can be interpreted by current theories of the transition of charged polypeptides and of titration curves of linear weak polyelectrolytes taking the effect of polymer concentration into consideration.", "publicationTitle": "Biophysical Chemistry", "publisher": "", "place": "", "date": "Oct 1975", "volume": "3", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "323-329", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Biophys. Chem.", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "96", "PMCID": "", "ISSN": "0301-4622", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Glutamates", "type": 1 }, { "tag": "Hydrogen-Ion Concentration", "type": 1 }, { "tag": "Mathematics", "type": 1 }, { "tag": "Osmolar Concentration", "type": 1 }, { "tag": "Peptides", "type": 1 }, { "tag": "Potassium Chloride", "type": 1 }, { "tag": "Potentiometry", "type": 1 }, { "tag": "Protein Conformation", "type": 1 }, { "tag": "Solutions", "type": 1 }, { "tag": "Thermodynamics", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2016-07-15T18:39:02Z", "dateModified": "2016-07-15T18:39:02Z" } }, { "key": "K74MZWFG", "version": 155, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/K74MZWFG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/K74MZWFG", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/324191/items/8R9HUKV2", "type": "application/json" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } } }, "data": { "key": "K74MZWFG", "version": 155, "parentItem": "8R9HUKV2", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2016-07-15T18:39:02Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/96", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2016-07-15T18:39:02Z", "dateModified": "2016-07-15T18:39:02Z" } }, { "key": "9G2F34C5", "version": 169, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/9G2F34C5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/9G2F34C5", "type": "text/html" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } }, "lastModifiedByUser": { "id": 1523048, "username": "Christian Flachsland", "name": "Christian Flachsland", "links": { "alternate": { "href": "https://www.zotero.org/christian_flachsland", "type": "text/html" } } }, "creatorSummary": "Moroi and Sato", "parsedDate": "1975-08-15", "numChildren": 1 }, "data": { "key": "9G2F34C5", "version": 169, "itemType": "journalArticle", "title": "Comparison between procaine and isocarboxazid metabolism in vitro by a liver microsomal amidase-esterase", "creators": [ { "creatorType": "author", "firstName": "K.", "lastName": "Moroi" }, { "creatorType": "author", "firstName": "T.", "lastName": "Sato" } ], "abstractNote": "", "publicationTitle": "Biochemical Pharmacology", "publisher": "", "place": "", "date": "Aug 15, 1975", "volume": "24", "issue": "16", "section": "", "partNumber": "", "partTitle": "", "pages": "1517-1521", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Biochem. Pharmacol.", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "8", "PMCID": "", "ISSN": "0006-2952", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Amidohydrolases", "type": 1 }, { "tag": "Animals", "type": 1 }, { "tag": "Esterases", "type": 1 }, { "tag": "Hydrogen-Ion Concentration", "type": 1 }, { "tag": "In Vitro Techniques", "type": 1 }, { "tag": "Isocarboxazid", "type": 1 }, { "tag": "Kinetics", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Metals", "type": 1 }, { "tag": "Microsomes, Liver", "type": 1 }, { "tag": "Phospholipids", "type": 1 }, { "tag": "Procaine", "type": 1 }, { "tag": "Proteins", "type": 1 }, { "tag": "Rats", "type": 1 }, { "tag": "Subcellular Fractions", "type": 1 }, { "tag": "Temperature", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2016-07-15T18:39:01Z", "dateModified": "2016-07-15T18:39:01Z" } }, { "key": "WVHX77AC", "version": 155, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/WVHX77AC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/WVHX77AC", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/324191/items/9G2F34C5", "type": "application/json" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } } }, "data": { "key": "WVHX77AC", "version": 155, "parentItem": "9G2F34C5", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2016-07-15T18:39:01Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/8", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2016-07-15T18:39:01Z", "dateModified": "2016-07-15T18:39:01Z" } }, { "key": "UEPAZJCJ", "version": 169, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/UEPAZJCJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/UEPAZJCJ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } }, "lastModifiedByUser": { "id": 1523048, "username": "Christian Flachsland", "name": "Christian Flachsland", "links": { "alternate": { "href": "https://www.zotero.org/christian_flachsland", "type": "text/html" } } }, "creatorSummary": "de Takats", "parsedDate": "1976-03", "numChildren": 1 }, "data": { "key": "UEPAZJCJ", "version": 169, "itemType": "journalArticle", "title": "Adequate use of heparin: the need for a flexible protocol", "creators": [ { "creatorType": "author", "firstName": "G.", "lastName": "de Takats" } ], "abstractNote": "", "publicationTitle": "IMJ. Illinois medical journal", "publisher": "", "place": "", "date": "Mar 1976", "volume": "149", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "245-247, 250", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "IMJ Ill Med J", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "5352", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Adequate use of heparin", "language": "eng", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Dose-Response Relationship, Drug", "type": 1 }, { "tag": "Heparin", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Thromboembolism", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2016-07-15T18:39:00Z", "dateModified": "2016-07-15T18:39:00Z" } }, { "key": "XH8GKWQD", "version": 155, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/XH8GKWQD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/XH8GKWQD", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/324191/items/UEPAZJCJ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } } }, "data": { "key": "XH8GKWQD", "version": 155, "parentItem": "UEPAZJCJ", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2016-07-15T18:39:00Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/5352", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2016-07-15T18:39:00Z", "dateModified": "2016-07-15T18:39:00Z" } }, { "key": "675GUV8D", "version": 169, "library": { "type": "group", "id": 324191, "name": "Climate Finance", "links": { "alternate": { "href": "https://www.zotero.org/groups/climate_finance", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/324191/items/675GUV8D", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/climate_finance/items/675GUV8D", "type": "text/html" } }, "meta": { "createdByUser": { "id": 967904, "username": "jansteckel", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jansteckel", "type": "text/html" } } }, "lastModifiedByUser": { "id": 1523048, "username": "Christian Flachsland", "name": "Christian Flachsland", "links": { "alternate": { "href": "https://www.zotero.org/christian_flachsland", "type": "text/html" } } }, "creatorSummary": "Lessmann et al.", "parsedDate": "1975-11-15", "numChildren": 1 }, "data": { "key": "675GUV8D", "version": 169, "itemType": "journalArticle", "title": "D-glucose-6-phosphate dehydrogenase (Entner-Doudoroff enzyme) from Pseudomonas fluorescens. Purification, properties and regulation", "creators": [ { "creatorType": "author", "firstName": "D.", "lastName": "Lessmann" }, { "creatorType": "author", "firstName": "K. L.", "lastName": "Schimz" }, { "creatorType": "author", "firstName": "G.", "lastName": "Kurz" } ], "abstractNote": "1. The existence of two different D-glucose-6-phosphate dehydrogenases in Pseudomonas fluorescens has been demonstrated. Based on their different specificity and their different metabolic regulation one enzyme is appointed to the Entner-Doudoroff pathway and the other to the hexose monophosphate pathway. 2. A procedure is described for the isolation of that D-glucose-6-phosphate dehydrogenase which forms part of the Entner-Doudoroff pathway (Entner-Doudoroff enzyme). A 950-fold purification was achieved with an overall yield of 44%. The final preparation, having a specific activity of about 300 mumol NADH formed per min per mg protein, was shown to be homogeneous. 3. The molecular weight of the Entner-Doudoroff enzyme has been determined to be 220000 by gel permeation chromatography, and that of the other enzyme (Zwischenferment) has been shown to be 265000. 4. The pI of the Entner-Doudoroff enzyme has been shown to be 5.24 and that of the Zwischenferment 4.27. The Entner-Doudoroff enzyme is stable in the range of pH 6 to 10.5 and shows its maximal activity at pH 8.9. 5. The Entner-Doudoroff enzyme showed specificity for NAD+ as well as for NADP+ and exhibited homotropic effects for D-glucose 6-phosphate. It is inhibited by ATP which acts as a negative allosteric effector. Other nucleoside triphosphates as well as ADP are also inhibitory. 6. The enzyme catalyzes the transfer of the axial hydrogen at carbon-1 of beta-D-glucopyranose 6-phosphate to the si face of carbon-4 of the nicotinamide ring and must be classified as B-side stereospecific dehydrogenase.", "publicationTitle": "European journal of biochemistry / FEBS", "publisher": "", "place": "", "date": "Nov 15, 1975", "volume": "59", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "545-559", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Eur. J. 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