[ { "key": "8XS3N77N", "version": 57, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/8XS3N77N", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/8XS3N77N", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Ramachandran et al.", "parsedDate": "2000", "numChildren": 0 }, "data": { "key": "8XS3N77N", "version": 57, "itemType": "journalArticle", "title": "Vascular complications in young Asian Indian patients with type 1 diabetes mellitus", "creators": [ { "creatorType": "author", "firstName": "A", "lastName": "Ramachandran" }, { "creatorType": "author", "firstName": "C", "lastName": "Snehalatha" }, { "creatorType": "author", "firstName": "R", "lastName": "Sasikala" }, { "creatorType": "author", "firstName": "K", "lastName": "Satyavani" }, { "creatorType": "author", "firstName": "V", "lastName": "Vijay" } ], "abstractNote": "To determine the prevalence of micro vascular and macro vascular complications in Asian Indian Type 1 diabetic subjects. There has been no major report on the prevalence of vascular complications in Type 1 diabetic patients in India. This study was done in Type 1 diabetic patients, aged < or =20 years at diagnosis of diabetes (n=617, M:F 322:295) with a minimum of 3 year follow-up. Standard diagnostic methodologies were used to test for micro vascular and macro vascular complications of diabetes. Retinopathy was detected in 13. 4% (background diabetic retinopathy 11.2%, proliferative diabetic retinopathy 1.9%, preproliferative 0.31%, maculopathy was seen in 13.3% of retinopathy cases), nephropathy in 7.1%, sensory neuropathy in 3.0%, ischaemic heart disease in 0.5% and peripheral vascular disease in 0.5% of the study subjects. Duration of diabetes showed positive association with retinopathy, nephropathy and neuropathy. Average glycosylated haemoglobin values, at follow up showed an association with retinopathy. Although the glycaemic control was suboptimal in the study group, prevalences of all complications, especially macro vascular complications were lower in Type 1 diabetic patients in this ethnic group, in comparison with the European or American counterparts.", "publicationTitle": "Diabetes Research & Clinical Practice", "publisher": "", "place": "", "date": "2000", "volume": "48", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "51–56", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Vascular complications in young Asian Indian patients with type 1 diabetes mellitus", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "I8Z85UHV", "version": 57, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/I8Z85UHV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/I8Z85UHV", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Qu et al.", "parsedDate": "2003", "numChildren": 0 }, "data": { "key": "I8Z85UHV", "version": 57, "itemType": "journalArticle", "title": "Value of coronary artery calcium scanning by computed tomography for predicting coronary heart disease in diabetic subjects", "creators": [ { "creatorType": "author", "firstName": "W", "lastName": "Qu" }, { "creatorType": "author", "firstName": "T T", "lastName": "Le" }, { "creatorType": "author", "firstName": "S P", "lastName": "Azen" }, { "creatorType": "author", "firstName": "M", "lastName": "Xiang" }, { "creatorType": "author", "firstName": "N D", "lastName": "Wong" }, { "creatorType": "author", "firstName": "T M", "lastName": "Doherty" }, { "creatorType": "author", "firstName": "R C", "lastName": "Detrano" } ], "abstractNote": "OBJECTIVE: The South Bay Heart Watch is a cohort study designed to determine the significance of coronary calcium in high-risk asymptomatic patients. This is a report of the relative risk (RR) for outcomes of coronary artery calcium in diabetic and nondiabetic subjects. RESEARCH DESIGN AND METHODS: A total of 1312 diabetic and nondiabetic subjects underwent risk factor screening and computed tomography testing for coronary calcium at baseline and were followed clinically for 6.3 +/- 1.4 years. End points were either 1). hard events of nonfatal myocardial infarction (MI) or coronary death or 2). any cardiovascular event (nonfatal MI, coronary death, coronary revascularization, or stroke). RESULTS: The incidence rates of a hard event and any cardiovascular event for diabetic and nondiabetic subjects were 14.5 and 6.1% and 23.8 and 12.2%, respectively (P < 0.001). Cox regression analyses of the combined risk relationship of diabetes status and calcium score demonstrated that relative to nondiabetic subjects with low calcium scores (<2.8), diabetic subjects with calcium scores >or=2.8 exhibited at least a fourfold increase in the risk of either a hard or any cardiovascular event (P < 0.001). Cox regression analyses conducted separately for nondiabetic and diabetic subjects revealed that coronary calcium score risk groups were significantly associated with events in nondiabetic subjects (RR >or= 2.6, P 0.05). CONCLUSIONS: The risk of coronary heart disease increases with increasing calcium scores and diabetes status. Calcium scores have less prognostic value in diabetic subjects.", "publicationTitle": "Diabetes Care", "publisher": "", "place": "", "date": "2003", "volume": "26", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "905–910", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Value of coronary artery calcium scanning by computed tomography for predicting coronary heart disease in diabetic subjects", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "77RZI7ZV", "version": 56, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/77RZI7ZV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/77RZI7ZV", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Saely et al.", "parsedDate": "2008", "numChildren": 0 }, "data": { "key": "77RZI7ZV", "version": 56, "itemType": "journalArticle", "title": "Type 2 diabetes significantly modulates the cardiovascular risk conferred by the PAI-1 - 675 4G/5G polymorphism in angiographied coronary patients", "creators": [ { "creatorType": "author", "firstName": "C H", "lastName": "Saely" }, { "creatorType": "author", "firstName": "A", "lastName": "Muendlein" }, { "creatorType": "author", "firstName": "A", "lastName": "Vonbank" }, { "creatorType": "author", "firstName": "G", "lastName": "Sonderegger" }, { "creatorType": "author", "firstName": "S", "lastName": "Aczel" }, { "creatorType": "author", "firstName": "P", "lastName": "Rein" }, { "creatorType": "author", "firstName": "L", "lastName": "Risch" }, { "creatorType": "author", "firstName": "H", "lastName": "Drexel" } ], "abstractNote": "Background: The association of the - 675 4G/5G polymorphism of the plasminogen activator inhibitor-1 (PAI-1) gene with cardiovascular disease in patients with type 2 diabetes (T2DM) is unknown. Methods: Genotyping was performed in 672 consecutive Caucasian patients undergoing coronary angiography for the evaluation of stable coronary artery disease (CAD). Vascular events were recorded over 4 years. Results: In non-diabetic subjects (n = 524), the homozygous PAI-1 4G4G genotype was significantly associated with significant coronary stenoses > 50% (adjusted odds ratio (OR) OR = 1.84 [1.17-2.92]; p = 0.009); however, in T2DM patients (n = 148) no such association was observed (OR = 0.67 [0.26-1.71]; p = 0.401). An interaction term T2DM x 4G4G genotype was significant (p = 0.006), indicating a significantly stronger association of the polymorphism with CAD in non-diabetic subjects than in patients with T2DM. Also prospectively, the 4G4G genotype conferred an increased risk of vascular events in non-diabetic subjects but not in T2DM patients (hazard ratios 1.76 [1.13-2.74]; p = 0.014 and 0.68 [0.30-1.54]; p = 0.360, respectively). Again, the interaction T2DM x 4G4G genotype was significant (p = 0.018). Conclusions: Presence of T2DM significantly modulates the vascular risk conferred by the PAI-1 - 675 4G/5G polymorphism in angiographied coronary patients. 2008 Elsevier B.V. All rights reserved.", "publicationTitle": "Clinica Chimica Acta", "publisher": "", "place": "", "date": "2008", "volume": "396", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "18–22", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Type 2 diabetes significantly modulates the cardiovascular risk conferred by the PAI-1 - 675 4G/5G polymorphism in angiographied coronary patients", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "P5MFH5HM", "S3UVJ8G2", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "ZUTTA29H", "version": 56, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/ZUTTA29H", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/ZUTTA29H", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Rockman et al.", "parsedDate": "2005", "numChildren": 0 }, "data": { "key": "ZUTTA29H", "version": 56, "itemType": "journalArticle", "title": "The safety of carotid endarterectomy in diabetic patients: clinical predictors of adverse outcome", "creators": [ { "creatorType": "author", "firstName": "C B", "lastName": "Rockman" }, { "creatorType": "author", "firstName": "S S", "lastName": "Saltzberg" }, { "creatorType": "author", "firstName": "T S", "lastName": "Maldonado" }, { "creatorType": "author", "firstName": "M A", "lastName": "Adelman" }, { "creatorType": "author", "firstName": "N S", "lastName": "Cayne" }, { "creatorType": "author", "firstName": "P J", "lastName": "Lamparello" }, { "creatorType": "author", "firstName": "T S", "lastName": "Riles" } ], "abstractNote": "OBJECTIVES: Patients with diabetes mellitus have been shown to have an increased incidence of complications after elective major vascular surgery. The objective of this study was to evaluate a large series of diabetic patients undergoing carotid endarterectomy (CEA) to determine if outcome differed from nondiabetic patients and to examine predisposing factors of poor outcome among diabetic patients. METHODS: A retrospective review of a prospectively compiled database was performed. From 1992 through 2000, 2151 CEAs were performed at our institution. Of these, 507 were in diabetic patients (23.6%), and the remaining 1644 procedures were in nondiabetic patients (76.4%). RESULTS: Diabetic patients were significantly more likely than nondiabetic patients to have hypertension (70.8% vs 64.5%, P = .01) and cardiac disease (54.6% vs 49.1%, P = .03). They were more likely than nondiabetic patients to be symptomatic before surgery (52.5% vs 47.1%, P = .04) and to have sustained a preoperative stroke (21.3% vs 17.7%, P = .07). No differences were noted in other recorded demographic factors or in intraoperative factors between diabetic and nondiabetic patients. Despite these differences, diabetic patients had similar perioperative outcomes compared with nondiabetic patients, including perioperative myocardial infarction (0.6% vs 0.4%, P = NS), perioperative death (0.8% vs 0.5%, P = NS), and perioperative neurologic events such as transient ischemic attack and stroke (3.2% vs 2.4%, P = NS). Among diabetic patients alone, cigarette smoking, general anesthesia, the use of a shunt, and the lack of clamp tolerance while under regional anesthesia predicted adverse perioperative neurologic outcome, and contralateral occlusion was associated with increased perioperative mortality. CONCLUSIONS: Despite an increased prevalence of cardiac disease and preoperative neurologic symptoms among diabetic patients undergoing CEA, the rates of perioperative cardiac morbidity, mortality, and stroke were equal to nondiabetic patients. In contrast to nondiabetic patients, current cigarette smoking appeared to predict increased adverse neurologic outcomes among diabetic patients, and the presence of contralateral occlusion among diabetic patients appeared to predispose them towards increased perioperative mortality. The use of a general anesthetic appeared to increased perioperative neurologic risk among diabetic patients; however, this may be related to surgeon bias in the selection of anesthetic technique. Although diabetic patients may have an increase in complications after other major vascular surgical procedures, the presence of diabetes mellitus does not appear to significantly increase risk.", "publicationTitle": "Journal of Vascular Surgery", "publisher": "", "place": "", "date": "2005", "volume": "42", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "878–883", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "The safety of carotid endarterectomy in diabetic patients: clinical predictors of adverse outcome", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "IZDKSG7D", "version": 56, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/IZDKSG7D", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/IZDKSG7D", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Zhang et al.", "parsedDate": "2010", "numChildren": 0 }, "data": { "key": "IZDKSG7D", "version": 56, "itemType": "journalArticle", "title": "Trends in the prevalence and comorbidities of diabetes mellitus in nursing home residents in the United States: 1995-2004", "creators": [ { "creatorType": "author", "firstName": "X.", "lastName": "Zhang" }, { "creatorType": "author", "firstName": "F. H.", "lastName": "Decker" }, { "creatorType": "author", "firstName": "H.", "lastName": "Luo" }, { "creatorType": "author", "firstName": "L. S.", "lastName": "Geiss" }, { "creatorType": "author", "firstName": "W. S.", "lastName": "Pearson" }, { "creatorType": "author", "firstName": "J. B.", "lastName": "Saaddine" }, { "creatorType": "author", "firstName": "E. W.", "lastName": "Gregg" }, { "creatorType": "author", "firstName": "A.", "lastName": "Albright" } ], "abstractNote": "OBJECTIVES: To estimate trends in the prevalence and comorbidities of diabetes mellitus (DM) in U.S. nursing homes from 1995 to 2004. DESIGN: SAS callable SUDAAN was used to adjust for the complex sample design and assess changes in prevalence of DM and comorbidities during the study period in the National Nursing Home Surveys. Trends were assessed using weighted least squares linear regression. Multiple logistic regressions were used to calculate predictive margins. SETTING: A continuing series of two-stage, cross-sectional probability national sampling surveys. PARTICIPANTS: Residents aged 55 and older: 1995 (n=7,722), 1997 (n=7,717), 1999 (n=7,809), and 2004 (n=12,786). MEASUREMENTS: DM and its comorbidities identified using a standard set of diagnosis codes. RESULTS: The estimated crude prevalence of DM increased from 16.9% in 1995 to 26.4% in 2004 in male nursing home residents and from 16.1% to 22.2% in female residents (all P<.05). Male and female residents aged 85 and older and those with high functional impairment showed a significant increasing trend in DM (all P<.05). In people with DM, multivariate-adjusted prevalence of cardiovascular disease increased from 59.6% to 75.4% for men and from 68.1% to 78.7% for women (all P<.05). Prevalence of most other comorbidities did not increase significantly. CONCLUSION: The burden of DM in residents of U.S. nursing homes has increased since 1995. This could be due to increasing DM prevalence in the general population or to changes in the population that nursing homes serve. Nursing home care practices may need to change to meet residents' changing needs. 2010, Copyright the Authors. Journal compilation 2010, The American Geriatrics Society.", "publicationTitle": "Journal of the American Geriatrics Society", "publisher": "", "place": "", "date": "2010", "volume": "58", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "724–730", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Trends in the prevalence and comorbidities of diabetes mellitus in nursing home residents in the United States: 1995-2004", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "JD7MPE9H", "version": 56, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/JD7MPE9H", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/JD7MPE9H", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Preis et al.", "parsedDate": "2009", "numChildren": 0 }, "data": { "key": "JD7MPE9H", "version": 56, "itemType": "journalArticle", "title": "Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005", "creators": [ { "creatorType": "author", "firstName": "S. R.", "lastName": "Preis" }, { "creatorType": "author", "firstName": "S. J.", "lastName": "Hwang" }, { "creatorType": "author", "firstName": "S.", "lastName": "Coady" }, { "creatorType": "author", "firstName": "M. J.", "lastName": "Pencina" }, { "creatorType": "author", "firstName": "R. B., Sr.", "lastName": "D'Agostino" }, { "creatorType": "author", "firstName": "P. J.", "lastName": "Savage" }, { "creatorType": "author", "firstName": "D.", "lastName": "Levy" }, { "creatorType": "author", "firstName": "C. S.", "lastName": "Fox" } ], "abstractNote": "BACKGROUND: Despite population declines in all-cause mortality, women with diabetes mellitus may have experienced an increase in mortality rates compared with men.\nMETHODS AND RESULTS: We examined change in all-cause, cardiovascular, and non-cardiovascular disease mortality rates among Framingham Heart Study participants who attended examinations during an \"earlier\" (1950 to 1975; n=930 deaths) and a \"later\" (1976 to 2001; n=773 deaths) time period. Diabetes mellitus was defined as casual glucose > or =200 mg/dL, fasting plasma glucose > or =126 mg/dL, or treatment. Among women, the hazard ratios (HRs) for all-cause mortality in the later versus the earlier time period were 0.59 (95% confidence interval, 0.50 to 0.70; P<0.0001) for those without diabetes mellitus and 0.48 (95% confidence interval, 0.32 to 0.71; P=0.002) for those with diabetes mellitus. Similar results were observed in men. Among women and men, the HR of cardiovascular disease mortality declined among those with and without diabetes mellitus. Non-cardiovascular disease mortality declined among women without diabetes mellitus (HR, 0.76; P=0.01), whereas no change was observed among women with diabetes mellitus or among men with or without diabetes mellitus. Individuals with versus those without diabetes mellitus were at increased risk of all-cause mortality in the earlier (HR, 2.44; P<0.0001) and later (HR, 1.95; P<0.0001) time periods.\nCONCLUSIONS: Reductions in all-cause mortality among women and men with diabetes mellitus have occurred over time. However, mortality rates among individuals with diabetes mellitus remain approximately 2-fold higher compared with individuals without diabetes mellitus.", "publicationTitle": "Circulation", "publisher": "", "place": "", "date": "2009", "volume": "119", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "1728-35", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Trends in all-cause and cardiovascular disease mortality among women and men with and without diabetes mellitus in the Framingham Heart Study, 1950 to 2005", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "62657RHS", "version": 56, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/62657RHS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/62657RHS", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Omrani et al.", "parsedDate": "2004", "numChildren": 1 }, "data": { "key": "62657RHS", "version": 56, "itemType": "journalArticle", "title": "Subclinical atherosclerosis and estimated glucose disposal rate as predictors of mortality in type 1 diabetes", "creators": [ { "creatorType": "author", "firstName": "G. H. R.", "lastName": "Omrani" }, { "creatorType": "author", "firstName": "M.", "lastName": "Soveid" }, { "creatorType": "author", "firstName": "H.", "lastName": "Rajaii" }, { "creatorType": "author", "firstName": "A. A.", "lastName": "Sadegholvaad" } ], "abstractNote": "Background: Chronic complications of diabetes causes substantial mortality and morbidity. The incidence and rate of progression of these complications depends on ethnic factors. The aim of this study was to investigate the incidence of late complications of diabetes and its relation to blood glucose control in a group of diabetic patients from South of Iran.\nMethods: In this retrospective study, medical records of all diabetic patients who were followed regularly during a 12 year period at outpatient clinics of Shiraz University of Medical Sciences were investigated. Information regarding age, sex, type of diabetes, duration of disease , mean fasting and postprandial blood sugar, complications (eye, kidneys, peripheral nerves, foot, cardiovascular, cerebrovascular), and timing of complications with regard to duration of disease were collected. Results: The study population included 392 patients (205 males and 186 females), 300 patients had type 2 and 92 had type 1 diabetes. The mean age at diagnosis was 20.4+/-12.8 years for type 1 and 47.5+/-10.4 years for type 2 patients. 95% of patients developed at least one chronic complication during the follow-up period. The incidence rates of eye , renal, and peripheral nerve complications were 51.5, 44.7, and 68.8 percent respectively. Diabetic foot problems occurred in 16.8 percent of cases and it led to amputation in 8.4 percent (33 cases) of patients. The incidence rates of cardiovascular and cerebrovascular complications were 49.7 and 15.3 percent respectively. The development of eye, renal, and peripheral nerve complications was related to blood sugar control.\nConclusion: Our diabetic patients developed chronic complications early and at a higher than expected rates. Future studies and more emphasis on prevention methods are recommended. This abstract was translated into English by the publisher or author.", "publicationTitle": "Iranian Journal of Diabetes & Lipid Disorders", "publisher": "", "place": "", "date": "2004", "volume": "3", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "E4-E4", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=jlh&AN=2005039671&site=ehost-live", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1726-7544", "archive": "jlh", "archiveLocation": "2005039671. Language: English. Entry Date: 20050218. Revision Date: 20091218. Publication Type: journal article", "shortTitle": "The incidence of chronic diabetic complications during a 12 years period in patients referring to clinics of Shiraz University of Medical Sciences", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Blood Glucose" }, { "tag": "Diabetes Mellitus -- Complications" }, { "tag": "Diabetic Retinopathy" }, { "tag": "Female" }, { "tag": "Human" }, { "tag": "Incidence -- Evaluation -- Iran" }, { "tag": "Iran" }, { "tag": "Male" }, { "tag": "Record Review" }, { "tag": "Retrospective Design" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "7TM9DTAA", "version": 55, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/7TM9DTAA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/7TM9DTAA", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Skriver et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "7TM9DTAA", "version": 55, "itemType": "journalArticle", "title": "Short-term impact of HbA1c on morbidity and all-cause mortality in people with type 2 diabetes: A Danish population-based observational study", "creators": [ { "creatorType": "author", "firstName": "M V", "lastName": "Skriver" }, { "creatorType": "author", "firstName": "H", "lastName": "Stovring" }, { "creatorType": "author", "firstName": "J K", "lastName": "Kristensen" }, { "creatorType": "author", "firstName": "M", "lastName": "Charles" }, { "creatorType": "author", "firstName": "A", "lastName": "Sandbaek" } ], "abstractNote": "Aims/hypothesis: In a population-based setting, we investigated whether diabetes-related morbidity and all-cause mortality within 2 years of HbA 1c measurement were associated with that HbA1c level in individuals with type 2 diabetes. The main objective was to compare outcomes in those with HbA1c > and <7% (53 mmol/mol). Methods: Individuals with type 2 diabetes from Aarhus County, Denmark, were identified from public data files in a 3 year period (2001-2003). Stratifying the 17,760 individuals by HbA1c, we estimated HRs for diabetes-related morbidities and all-cause mortality using Cox regression. Results were also stratified by treatment modality. Results: In total, 1,805 individuals experienced at least one diabetes-related morbidity and 1,859 individuals died. In general, the HRs in adjusted analyses of diabetes-related morbidity and mortality were increased for HbA1c > 7% (53 mmol/mol): morbidity, HR 1.48 (95% CI 1.34, 1.63); and mortality, HR 1.26 (95% CI 1.15, 1.39). On grouping individuals according to HbA1c <5% (31 mmol/mol), 5.0-5.9% (31-41 mmol/mol), 6.0-6.9% (42-52 mmol/mol), 7.0-7.9% (53-63 mmol/mol), 8.0-8.9% (64-74 mmol/mol) and >9% (75 mmol/mol), the HRs for mortality formed a U shape, with HbA 1c 6.0-6.9% (42-52 mmol/mol) at the lowest point. For diabetes-related morbidity, a dose-response pattern appeared (lowest for HbA1c < 5% [31 mmol/mol]). Patterns of HR differed with treatment modality. Conclusions/interpretation: An HbA1c level >7% (53 mmol/mol) was associated with increased morbidity and mortality. Both high and very low levels of HbA1c were associated with increased mortality. A dose-response pattern appeared for morbidity. The impact of HbA1c level on morbidity and mortality depended on treatment modality. 2012 Springer-Verlag.", "publicationTitle": "Diabetologia", "publisher": "", "place": "", "date": "2012", "volume": "55", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "2361–2370", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Short-term impact of HbA1c on morbidity and all-cause mortality in people with type 2 diabetes: A Danish population-based observational study", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Maybe include" }, { "tag": "found and saved" }, { "tag": "further information required" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "XSWSE392", "version": 55, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/XSWSE392", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/XSWSE392", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Roche and Wang", "parsedDate": "2013", "numChildren": 1 }, "data": { "key": "XSWSE392", "version": 55, "itemType": "journalArticle", "title": "Sex differences in all-cause and cardiovascular mortality, hospitalization for individuals with and without diabetes, and patients with diabetes diagnosed early and late", "creators": [ { "creatorType": "author", "firstName": "M M", "lastName": "Roche" }, { "creatorType": "author", "firstName": "P P", "lastName": "Wang" } ], "abstractNote": "OBJECTIVE: To compare risk of all-cause mortality, cardiovascular disease (CVD) mortality, acute myocardial infarction (AMI) mortality, stroke mortality, and hospitalizations for males and females with and without diabetes and those with diabetes diagnosed early and late. RESEARCH DESIGN AND METHODS: We conducted a population-based retrospective cohort study including 73,783 individuals aged 25 years or older in Newfoundland and Labrador, Canada (15,152 with diabetes; 9,517 with late diagnoses). RESULTS: Males and females with diabetes had an increased risk of all-cause mortality, CVD mortality, AMI mortality, and CVD hospitalizations compared with individuals without diabetes, and the risk was stronger in females than in males. For females, risks of all-cause mortality (hazard ratio [HR] 1.85 [95% CI 1.74-1.96]) and CVD hospitalizations (2.57 [2.24-2.94]) were significantly higher compared with their male counterparts (1.59 [1.51-1.69] and 1.92 [1.72-2.14]). Females with diabetes diagnosed late had an increased risk of CVD mortality (6.54 [4.80-8.91]) and CVD hospitalizations (5.22 [4.31-6.33]) compared with females without diabetes, and both were significantly higher compared with their male counterparts (3.44 [2.47-4.79]) and (3.33 [2.80-3.95]). CONCLUSIONS: Females with diabetes have a greater risk of mortality than males with diabetes. CVD has a greater impact on females with diabetes than males, especially when diagnosed at a later stage. Different management strategies should be considered for males and females and those with early and late diagnoses of diabetes.", "publicationTitle": "Diabetes Care", "publisher": "", "place": "", "date": "2013", "volume": "36", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "2582–2590", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Sex differences in all-cause and cardiovascular mortality, hospitalization for individuals with and without diabetes, and patients with diabetes diagnosed early and late", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "TKGS7BXC", "version": 55, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/TKGS7BXC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/TKGS7BXC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Swaminathan et al.", "parsedDate": "2004", "numChildren": 0 }, "data": { "key": "TKGS7BXC", "version": 55, "itemType": "journalArticle", "title": "Socioeconomic status, cardiovascular risk factors and the incidence of microvascular and macrovascular disease in type 1 diabetes", "creators": [ { "creatorType": "author", "firstName": "K.", "lastName": "Swaminathan" }, { "creatorType": "author", "firstName": "S.", "lastName": "Lewis" }, { "creatorType": "author", "firstName": "A. D.", "lastName": "Morris" } ], "abstractNote": "This study was undertaken to explore the associations between socioeconomic deprivation, prevalent cardiovascular risk factors and the development of microvascular and macrovascular complications in a cohort of subjects with type 1 diabetes mellitus in Scotland. We identified 2,314 people with type 1 diabetes from clinic records in six Scottish regions from 1989 to 1996. Postcode sectors were used to determine the Carstairs Index as a proxy for socioeconomic status. Clinic records and linkage to Scottish morbidity records allowed the association of socioeconomic status with the development of microvascular and macrovascular disease and the prevalence of cardiovascular risk factors to be evaluated. There was no overall association between prevalence of disease and socioeconomic status. There was a significant univariate relationship between smoking and deprivation (trend test p<0.00001; 47% of the most deprived were current smokers compared to 25% of the least deprived). Multivariate analysis showed that raised blood pressure, increasing age, smoking, high glycated haemoglobin and albuminuria were all independently associated with the development of macrovascular disease. Raised blood pressure, increasing duration of diabetes and high glycated haemoglobin were independently associated with microvascular disease. No associations were observed between either medical problem and socioeconomic status either before or after adjustment for other factors. Our study concluded that social deprivation is associated with an increased risk of smoking. Our results did not confirm a tendency to poor glycaemic or blood pressure control in people who are deprived and there was no association between deprivation and incident microvascular or macrovascular disease.", "publicationTitle": "British Journal of Diabetes & Vascular Disease", "publisher": "", "place": "", "date": "2004", "volume": "4", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "180–188 %U http://search.ebscohost.com/login.aspx?direct=true&db=jlh&AN=2005077055&site=ehost-live", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Socioeconomic status, cardiovascular risk factors and the incidence of microvascular and macrovascular disease in type 1 diabetes", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Cardiovascular Diseases – Epidemiology" }, { "tag": "Cardiovascular Diseases – Etiology" }, { "tag": "Data Analysis" }, { "tag": "Descriptive Statistics" }, { "tag": "Diabetes Mellitus" }, { "tag": "Female" }, { "tag": "Human" }, { "tag": "Male" }, { "tag": "Middle Age" }, { "tag": "Prevalence" }, { "tag": "Risk Factors" }, { "tag": "Scales" }, { "tag": "Scotland" }, { "tag": "Socioeconomic Factors" }, { "tag": "Statistical" }, { "tag": "Type 1 – Complications" }, { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "85GQ2H3W", "version": 55, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/85GQ2H3W", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/85GQ2H3W", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Otiniano et al.", "parsedDate": "2003-07", "numChildren": 0 }, "data": { "key": "85GQ2H3W", "version": 55, "itemType": "journalArticle", "title": "Self-reported heart attack in Mexican-American elders: Examination of incidence, prevalence, and 7-year mortality", "creators": [ { "creatorType": "author", "firstName": "M. E.", "lastName": "Otiniano" }, { "creatorType": "author", "firstName": "K. J.", "lastName": "Ottenbacher" }, { "creatorType": "author", "firstName": "K. S.", "lastName": "Markides" }, { "creatorType": "author", "firstName": "L. A.", "lastName": "Ray" }, { "creatorType": "author", "firstName": "X. L.", "lastName": "Du" } ], "abstractNote": "OBJECTIVES: To examine the prevalence, incidence, and mortality of self-reported heart attack in older Mexican Americans and to identify significant factors associated with heart attack. DESIGN: Cross-sectional and longitudinal study. SETTING: Baseline and three follow-up interviews in five southwestern states (Arizona, California, Colorado, New Mexico, and Texas) of the Hispanic Established Population for the Epidemiological Study of the Elderly. PARTICIPANTS: Three thousand fifty Mexican Americans aged 65 to 107 (mean age = 73). MEASUREMENTS: Sociodemographic factors (age, sex, marital status, language of interview, health insurance coverage, living arrangements, and financial strain) and health factors (smoking, alcohol consumption, obesity, diabetes mellitus, hypertension, stroke, cancer, hip fracture, arthritis, depression, limitations in activities of daily living (ADLs) and instrumental activities of daily living (IADLs), and mortality) were determined at baseline (1993-94). New heart attacks were assessed at follow-ups in 1995-96, 1998-99, and 2000-01. Vital status was determined over the 7-year follow-up. RESULTS: Prevalence of self-reported heart attack was 9.1% at baseline. Incidence of self-reported heart attack was 6.1%, 9.1%, and 7.9%, respectively, for the three subsequent follow-ups. Older age, male sex, diabetes mellitus, hypertension, and stroke were significantly associated with heart attack at baseline. Age was a significant predictor for new heart attack at each follow-up. Having ADL (odds ratio (OR) = 2.91, 95% confidence interval (CI) = 2.19-3.86) and IADL (OR = 2.25, CI = 1.72-2.94) disabilities was significantly associated with self-reported heart attack. Subjects with heart attack were significantly more likely to die at 7 years (hazard ratio = 1.57, 95% CI = 1.29-1.91). Of those with self-reported heart attack, 42.4% had died of heart attack as the underlying cause of death by 7-year follow-up. CONCLUSION: In Mexican Americans, self-reported heart attack was associated with being older and male and having diabetes mellitus, hypertension, stroke, and ADL and IADL disabilities. Nearly half of subjects with heart attack had died of heart attack as underlying cause of death by 7-year follow-up. Prevention and control for this disease would be especially important in this population to avoid early mortality.", "publicationTitle": "Journal of the American Geriatrics Society", "publisher": "", "place": "", "date": "2003 Jul", "volume": "51", "issue": "7", "section": "", "partNumber": "", "partTitle": "", "pages": "923-929", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "2003292907", "shortTitle": "Self-reported heart attack in Mexican-American elders: Examination of incidence, prevalence, and 7-year mortality", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "S6XMJXIA", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/S6XMJXIA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/S6XMJXIA", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Tonelli et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "S6XMJXIA", "version": 54, "itemType": "journalArticle", "title": "Risk of coronary events in people with chronic kidney disease compared with those with diabetes: A population-level cohort study", "creators": [ { "creatorType": "author", "firstName": "M.", "lastName": "Tonelli" }, { "creatorType": "author", "firstName": "P.", "lastName": "Muntner" }, { "creatorType": "author", "firstName": "A.", "lastName": "Lloyd" }, { "creatorType": "author", "firstName": "B. J.", "lastName": "Manns" }, { "creatorType": "author", "firstName": "S.", "lastName": "Klarenbach" }, { "creatorType": "author", "firstName": "N.", "lastName": "Pannu" }, { "creatorType": "author", "firstName": "M. T.", "lastName": "James" }, { "creatorType": "author", "firstName": "B. R.", "lastName": "Hemmelgarn" } ], "abstractNote": "Background Diabetes is regarded as a coronary heart disease risk equivalent-ie, people with the disorder have a risk of coronary events similar to those with previous myocardial infarction. We assessed whether chronic kidney disease should be regarded as a coronary heart disease risk equivalent. Methods We studied a population-based cohort with measures of estimated glomerular filtration rate (eGFR) and proteinuria from Alberta, Canada. We used validated algorithms based on hospital admission and medical-claim data to classify participants with baseline history of myocardial infarction or diabetes and to ascertain which patients were admitted to hospital for myocardial infarction during follow-up (the primary outcome). For our primary analysis, we defined baseline chronic kidney disease as eGFR 15-59.9 mL/min per 1.73 m2 (stage 3 or 4 disease). We used Poisson regression to calculate unadjusted rates and relative rates of myocardial infarction during follow-up for five risk groups: people with previous myocardial infarction (with or without diabetes or chronic kidney disease), and (of those without previous myocardial infarction), four mutually exclusive groups defined by the presence or absence of diabetes and chronic kidney disease. Findings During a median follow-up of 48 months (IQR 25-65), 11 340 of 1 268 029 participants (1%) were admitted to hospital with myocardial infarction. The unadjusted rate of myocardial infarction was highest in people with previous myocardial infarction (18.5 per 1000 person-years, 95% CI 17.4-19.8). In people without previous myocardial infarction, the rate of myocardial infarction was lower in those with diabetes (without chronic kidney disease) than in those with chronic kidney disease (without diabetes; 5.4 per 1000 person-years, 5.2-5.7, vs 6.9 per 1000 personyears, 6.6-7.2; p<0.0001). The rate of incident myocardial infarction in people with diabetes was substantially lower than for those with chronic kidney disease when defined by eGFR of less than 45 mL/min per 1.73 m2 and severely increased proteinuria (6.6 per 1000 person-years, 6.4-6.9 vs 12.4 per 1000 person-years, 9.7-15.9). Interpretation Our findings suggest that chronic kidney disease could be added to the list of criteria defining people at highest risk of future coronary events. Funding Alberta Heritage Foundation for Medical Research.", "publicationTitle": "The Lancet", "publisher": "", "place": "", "date": "2012", "volume": "380", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "807–814", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Risk of coronary events in people with chronic kidney disease compared with those with diabetes: A population-level cohort study", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "K78A5HQX", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/K78A5HQX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/K78A5HQX", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Shimajiri et al.", "parsedDate": "2008", "numChildren": 0 }, "data": { "key": "K78A5HQX", "version": 54, "itemType": "journalArticle", "title": "Prevalence of metabolic syndrome in Japanese type 2 diabetic patients and its significance for chronic vascular complications", "creators": [ { "creatorType": "author", "firstName": "Y", "lastName": "Shimajiri" }, { "creatorType": "author", "firstName": "K", "lastName": "Tsunoda" }, { "creatorType": "author", "firstName": "M", "lastName": "Furuta" }, { "creatorType": "author", "firstName": "Y", "lastName": "Kadoya" }, { "creatorType": "author", "firstName": "S", "lastName": "Yamada" }, { "creatorType": "author", "firstName": "K", "lastName": "Nanjo" }, { "creatorType": "author", "firstName": "T", "lastName": "Sanke" } ], "abstractNote": "Prevalence of metabolic syndrome (MetS) in type 2 diabetes and its association with vascular complications were studied in 637 Japanese type 2 diabetic patients. MetS was diagnosed using criteria proposed by the Japanese study group for the definition of MetS in 2005. The prevalence of MetS in patients studied was higher in males (45.9%) than females (28.0%). The prevalence of MetS was 53.0% in males and 35.4% in females in patients with duration of less than 10 years, and decreased with an increase in duration. Upon comparing patients groups complicated with and without MetS, we determined the MetS group had significantly higher levels of fasting serum C-peptide and high-sensitivity C-reactive protein, and a significantly lower level of serum adiponectin. However, the prevalence of coronary heart disease, brain infarction, or peripheral arterial disease was not significantly different between these groups. On the other hand, the prevalence of microangiopathy in the group with MetS was significantly higher than in that without MetS, and became significantly higher along with an increase in duration. This study clarifies the prevalence of MetS in Japanese type 2 diabetic patients, and suggests that MetS is associated with microangiopathy rather than macroangiopathy in Japanese type 2 diabetic patients.", "publicationTitle": "Diabetes Research & Clinical Practice", "publisher": "", "place": "", "date": "2008", "volume": "79", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "310–317", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0168-8227", "archive": "", "archiveLocation": "", "shortTitle": "Prevalence of metabolic syndrome in Japanese type 2 diabetic patients and its significance for chronic vascular complications", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Age of Onset" }, { "tag": "Aged" }, { "tag": "Body Mass Index" }, { "tag": "C-Peptide – Blood" }, { "tag": "Chronic Disease" }, { "tag": "Diabetes Mellitus" }, { "tag": "Female" }, { "tag": "Human" }, { "tag": "Japan" }, { "tag": "Male" }, { "tag": "Maybe include" }, { "tag": "Metabolic Syndrome X – Blood" }, { "tag": "Metabolic Syndrome X – Complications" }, { "tag": "Metabolic Syndrome X – Epidemiology" }, { "tag": "Middle Age" }, { "tag": "Prevalence" }, { "tag": "Type 2 – Blood" }, { "tag": "Type 2 – Epidemiology" }, { "tag": "Vascular Diseases – Complications" }, { "tag": "Vascular Diseases – Epidemiology" }, { "tag": "might have information on CVD prevalence" }, { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "UBAURKCM", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/UBAURKCM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/UBAURKCM", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Shemesh et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "UBAURKCM", "version": 54, "itemType": "journalArticle", "title": "Relation of coronary artery calcium to cardiovascular risk in patients with combined diabetes mellitus and systemic hypertension", "creators": [ { "creatorType": "author", "firstName": "J", "lastName": "Shemesh" }, { "creatorType": "author", "firstName": "M", "lastName": "Motro" }, { "creatorType": "author", "firstName": "N", "lastName": "Morag-Koren" }, { "creatorType": "author", "firstName": "E", "lastName": "Konen" }, { "creatorType": "author", "firstName": "E", "lastName": "Grossman" } ], "abstractNote": "Certain patients with type 2 diabetes mellitus (DM) do not have increased cardiovascular (CV) risk. The aim of the present study was to stratify hypertensive adults with DM into those with low or high CV risk according to the absence or presence of coronary artery calcium (CAC). The study group included 423 patients, a subgroup of the 544 participants in the calcification side arm of the International Nifedipine Study: Intervention as Goal for Hypertension Therapy. All underwent a baseline computed tomography scan with an unenhanced dual-detector spiral computed tomography scan for CAC measurements. All were free of CV disease and completed 3 years (short-term) of follow-up. A total of 268 patients were included in the 15-year (long-term) follow-up period. The study group was divided into 4 subgroups according to the presence or absence of DM and CAC and was analyzed for a first CV event. Of the 423 patients, 164 (39%) had DM. Cardiovascular events occurred in 41 patients during the first 3 years and in 111 of 268 patients during the long-term follow-up. The rate of CV events was greater in the patients with DM with CAC than in those without (15% vs 7% after 3 years and 52% vs 32% after 15 years). Compared to those without DM without CAC, the short-term adjusted hazard ratio for CV event in those with DM with and without CAC was 6.6 (95% confidence interval 1.4 to 30.5) and 3.9 (95% confidence interval 0.7 to 22.6), respectively. A similar trend was seen in the long-term follow-up study. In conclusion, patients with hypertension and DM can be stratified into a lower CV risk in the absence of CAC. Copyright A 2012 Elsevier Inc. All rights reserved.", "publicationTitle": "American Journal of Cardiology", "publisher": "", "place": "", "date": "2012", "volume": "109", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "844–850", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Relation of coronary artery calcium to cardiovascular risk in patients with combined diabetes mellitus and systemic hypertension", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "include" }, { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "TARIW3K8", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/TARIW3K8", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/TARIW3K8", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Soedamah-Muthu et al.", "parsedDate": "2004", "numChildren": 0 }, "data": { "key": "TARIW3K8", "version": 54, "itemType": "journalArticle", "title": "Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study", "creators": [ { "creatorType": "author", "firstName": "S S", "lastName": "Soedamah-Muthu" }, { "creatorType": "author", "firstName": "N", "lastName": "Chaturvedi" }, { "creatorType": "author", "firstName": "M", "lastName": "Toeller" }, { "creatorType": "author", "firstName": "B", "lastName": "Ferriss" }, { "creatorType": "author", "firstName": "P", "lastName": "Reboldi" }, { "creatorType": "author", "firstName": "G", "lastName": "Michel" }, { "creatorType": "author", "firstName": "C", "lastName": "Manes" }, { "creatorType": "author", "firstName": "J H", "lastName": "Fuller" }, { "creatorType": "author", "firstName": "Eurodiab Prospective Complications Study", "lastName": "Group" } ], "abstractNote": "OBJECTIVE: The goal of the study was to examine risk factors in the prediction of coronary heart disease (CHD) and differences in men and women in the EURODIAB Prospective Complications Study. RESEARCH DESIGN AND METHODS: Baseline risk factors and CHD at follow-up were assessed in 2,329 type 1 diabetic patients without prior CHD. CHD was defined as physician-diagnosed myocardial infarction, angina pectoris, coronary artery bypass graft surgery, and/or Minnesota-coded ischemic electrocardiograms or fatal CHD. RESULTS: There were 151 patients who developed CHD, and the 7-year incidence rate was 8.0 (per 1,000 person-years) in men and 10.2 in women. After adjustment for age and/or duration of diabetes, the following risk factors were related to CHD in men: age, GHb, waist-to-hip ratio (WHR), HDL cholesterol, smoking, albumin excretion rate (AER), and autonomic neuropathy. The following risk factors were related to CHD in women: age, systolic blood pressure (BP), fasting triglycerides, AER, and retinopathy. Multivariate standardized Cox proportional hazards models showed that age (hazard ratio 1.5), AER (1.3 in men and 1.6 in women), WHR (1.3 in men), smoking (1.5 in men), fasting triglycerides (1.3 in women) or HDL cholesterol (0.74 in women), and systolic BP (1.3 in women) were predictors of CHD. CONCLUSIONS: This study supports the evidence for a strong predictive role of baseline albuminuria in the pathogenesis of CHD in type 1 diabetes. Furthermore, sex-specific risk factors such as systolic BP, fasting triglycerides (or HDL cholesterol), and WHR were found to be important in the development of CHD.", "publicationTitle": "Diabetes Care", "publisher": "", "place": "", "date": "2004", "volume": "27", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "530–537", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Risk factors for coronary heart disease in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" }, { "tag": "include" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "BQGVXTFH", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/BQGVXTFH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/BQGVXTFH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Sever et al.", "parsedDate": "2005", "numChildren": 0 }, "data": { "key": "BQGVXTFH", "version": 54, "itemType": "journalArticle", "title": "Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial–lipid-lowering arm (ASCOT-LLA)", "creators": [ { "creatorType": "author", "firstName": "P S", "lastName": "Sever" }, { "creatorType": "author", "firstName": "N R", "lastName": "Poulter" }, { "creatorType": "author", "firstName": "B", "lastName": "Dahlof" }, { "creatorType": "author", "firstName": "H", "lastName": "Wedel" }, { "creatorType": "author", "firstName": "R", "lastName": "Collins" }, { "creatorType": "author", "firstName": "G", "lastName": "Beevers" }, { "creatorType": "author", "firstName": "M", "lastName": "Caulfield" }, { "creatorType": "author", "firstName": "S E", "lastName": "Kjeldsen" }, { "creatorType": "author", "firstName": "A", "lastName": "Kristinsson" }, { "creatorType": "author", "firstName": "G T", "lastName": "McInnes" }, { "creatorType": "author", "firstName": "J", "lastName": "Mehlsen" }, { "creatorType": "author", "firstName": "M", "lastName": "Nieminen" }, { "creatorType": "author", "firstName": "E", "lastName": "O'Brien" }, { "creatorType": "author", "firstName": "J", "lastName": "Ostergren" }, { "creatorType": "author", "firstName": "B", "lastName": "Dahlöf" }, { "creatorType": "author", "firstName": "H", "lastName": "Wedel" }, { "creatorType": "author", "firstName": "R", "lastName": "Collins" }, { "creatorType": "author", "firstName": "G", "lastName": "Beevers" }, { "creatorType": "author", "firstName": "M", "lastName": "Caulfield" }, { "creatorType": "author", "firstName": "S E", "lastName": "Kjeldsen" }, { "creatorType": "author", "firstName": "A", "lastName": "Kristinsson" }, { "creatorType": "author", "firstName": "G T", "lastName": "McInnes" }, { "creatorType": "author", "firstName": "J", "lastName": "Mehlsen" }, { "creatorType": "author", "firstName": "M", "lastName": "Nieminen" }, { "creatorType": "author", "firstName": "E", "lastName": "O'Brien" }, { "creatorType": "author", "firstName": "J", "lastName": "Ostergren" } ], "abstractNote": "OBJECTIVE: This study aims to establish the benefits of lowering cholesterol in diabetic patients with well-controlled hypertension and average/below-average cholesterol concentrations, but without established coronary disease. RESEARCH DESIGN AND METHODS: In the lipid-lowering arm of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT-LLA), 10,305 hypertensive patients with no history of coronary heart disease (CHD) but at least three cardiovascular risk factors were randomly assigned to receive 10 mg atorvastatin or placebo. Effects on total cardiovascular outcomes in 2,532 patients who had type 2 diabetes at randomization were compared. RESULTS: During a median follow-up of 3.3 years, concentrations of total and LDL cholesterol among diabetic participants included in ASCOT-LLA were approximately 1 mmol/l lower in those allocated atorvastatin compared with placebo. There were 116 (9.2%) major cardiovascular events or procedures in the atorvastatin group and 151 (11.9%) events in the placebo group (hazard ratio 0.77, 95% CI 0.61-0.98; P = 0.036). For the individual components of this composite end point, the number of events occurring in the diabetes subgroup was small. Therefore, although fewer coronary events (0.84, 0.55-1.29; P = 0.14) and strokes (0.67, 0.41-1.09; P = 0.66) were observed among the patients allocated atorvastatin, these reductions were not statistically significant. CONCLUSIONS: Atorvastatin significantly reduced the risk of major cardiovascular events and procedures among diabetic patients with well-controlled hypertension and without a history of CHD or markedly elevated cholesterol concentrations. The proportional reduction in risk was similar to that among participants who did not have diagnosed diabetes. Allocation to atorvastatin prevented approximately 9 diabetic participants from suffering a first major cardiovascular event or procedure for every 1,000 treated for 1 year.", "publicationTitle": "Diabetes Care", "publisher": "", "place": "", "date": "2005", "volume": "28", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "1151–1157", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0149-5992", "archive": "", "archiveLocation": "", "shortTitle": "Reduction in cardiovascular events with atorvastatin in 2,532 patients with type 2 diabetes: Anglo-Scandinavian Cardiac Outcomes Trial–lipid-lowering arm (ASCOT-LLA)", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Atorvastatin – Administration and Dosage Diabetes Mellitus" }, { "tag": "T" }, { "tag": "found and saved" }, { "tag": "include" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "K5BWNZRD", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/K5BWNZRD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/K5BWNZRD", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Salles et al.", "parsedDate": "2013-11", "numChildren": 0 }, "data": { "key": "K5BWNZRD", "version": 54, "itemType": "journalArticle", "title": "Prognostic impact of clinic and ambulatory blood pressure components in high-risk type 2 diabetic patients: The Rio de Janeiro Type 2 Diabetes Cohort Study", "creators": [ { "creatorType": "author", "firstName": "G. F.", "lastName": "Salles" }, { "creatorType": "author", "firstName": "N. C.", "lastName": "Leite" }, { "creatorType": "author", "firstName": "B. B.", "lastName": "Pereira" }, { "creatorType": "author", "firstName": "E. M.", "lastName": "Nascimento" }, { "creatorType": "author", "firstName": "C. R. L.", "lastName": "Cardoso" } ], "abstractNote": "BACKGROUND:: The prognostic importance of tight clinic blood pressure (BP) control is controversial in diabetic patients. The objective was to investigate the prognostic impact of clinic and ambulatory BPs for cardiovascular morbidity and mortality in type 2 diabetes. METHODS:: In a prospective cohort study, 565 type 2 diabetic patients had clinical, laboratory and ambulatory BP monitoring (ABPM) data obtained at baseline and during follow-up. The primary endpoints were a composite of fatal and nonfatal cardiovascular events and all-cause mortality. Multivariable Cox survival and splines regression analyses assessed associations between each BP component [SBP, DBP and pulse pressure (PP)] and the endpoints. RESULTS:: After a median follow-up of 5.75 years, 88 total cardiovascular events and 70 all-cause deaths occurred. After adjustments for cardiovascular risk factors, clinic SBP and DBPs were predictive of the composite endpoint but not of all-cause mortality, whereas all ambulatory BP components were predictors of both endpoints. Ambulatory systolic and PPs were the strongest predictors and achieved ambulatory BPs during follow-up improved risk prediction in relation to baseline values. When categorized at clinically relevant cut-off values, risk began only at clinic BPs at least 140/90aSmmHg, whereas for ambulatory BPs it began at lower values (>120/75aSmmHg for the 24-h period). CONCLUSION:: ABPM provides more valuable information regarding cardiovascular risk stratification than office BPs and should be performed, if possible, in every high-risk type 2 diabetic patient. Achieved 24-h ambulatory BPs less than 120/75aSmmHg are associated with significant cardiovascular protection and, if confirmed by other studies, may be considered as BP treatment targets. 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.", "publicationTitle": "Journal of Hypertension", "publisher": "", "place": "", "date": "2013 November", "volume": "31", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "2176-2186", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Prognostic impact of clinic and ambulatory blood pressure components in high-risk type 2 diabetic patients: The Rio de Janeiro Type 2 Diabetes Cohort Study", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "ATHF292A", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/ATHF292A", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/ATHF292A", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Roy et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "ATHF292A", "version": 54, "itemType": "journalArticle", "title": "Relationship of retinal vessel caliber to cardiovascular disease and mortality in African Americans with type 1 diabetes mellitus", "creators": [ { "creatorType": "author", "firstName": "M S", "lastName": "Roy" }, { "creatorType": "author", "firstName": "R", "lastName": "Klein" }, { "creatorType": "author", "firstName": "M N", "lastName": "Janal" } ], "abstractNote": "", "publicationTitle": "Archives of Ophthalmology", "publisher": "", "place": "", "date": "2012", "volume": "130", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "561–567", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0003-9950", "archive": "", "archiveLocation": "", "shortTitle": "Relationship of retinal vessel caliber to cardiovascular disease and mortality in African Americans with type 1 diabetes mellitus", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adult" }, { "tag": "Blacks – Statistics and Numerical Data" }, { "tag": "Cardiovascular Diseases – Mortality" }, { "tag": "Diabetes Mellitus" }, { "tag": "Female" }, { "tag": "Human" }, { "tag": "Hypertension – Mortality" }, { "tag": "Incidence" }, { "tag": "Male" }, { "tag": "Retinal Artery – Pathology" }, { "tag": "Retinal Vein – Pathology" }, { "tag": "Risk Factors" }, { "tag": "Type 1 – Mortality" }, { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "P5MFH5HM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "KTJWQ9Z2", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/KTJWQ9Z2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/KTJWQ9Z2", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Rana et al.", "parsedDate": "2005", "numChildren": 0 }, "data": { "key": "KTJWQ9Z2", "version": 54, "itemType": "journalArticle", "title": "QT interval abnormalities are often present at diagnosis in diabetes and are better predictors of cardiac death than ankle brachial pressure index and autonomic function tests", "creators": [ { "creatorType": "author", "firstName": "B S", "lastName": "Rana" }, { "creatorType": "author", "firstName": "P O", "lastName": "Lim" }, { "creatorType": "author", "firstName": "A A", "lastName": "Naas" }, { "creatorType": "author", "firstName": "S A", "lastName": "Ogston" }, { "creatorType": "author", "firstName": "R W", "lastName": "Newton" }, { "creatorType": "author", "firstName": "R T", "lastName": "Jung" }, { "creatorType": "author", "firstName": "A D", "lastName": "Morris" }, { "creatorType": "author", "firstName": "A D", "lastName": "Struthers" } ], "abstractNote": "OBJECTIVES: To study serial measures of maximum QT interval corrected for heart rate (QTc) and QT dispersion (QTD) and their association with cardiac mortality patients with non-insulin dependent diabetes and to compare QT abnormalities with other mortality predictors (ankle brachial pressure index (ABPI) and autonomic function tests) in their ability to predict cardiac death. SETTING: Teaching hospital. METHODS AND PATIENTS: QT interval analysis, heart rate (RR) variation in response to deep breathing and standing, and ABPI were analysed in 192 patients with non-insulin dependent diabetes. Cardiac death was the primary end point. RESULTS: Mean (SD) follow up was 12.7 (3.2) years (range 1.2-17.1 years). There were 48 deaths, of which 26 were cardiac. QTc and QTD were individually significant predictors of cardiac mortality throughout the follow up period (p < 0.001). The predictability of QT parameters was superior to the predictability of ABPI and RR interval analysis. Temporal changes in QT parameters showed that the mean absolute QT parameter was a significant predictor of cardiac death (p < 0.001), whereas an intraindividual change in QT parameter over time was not predictive. CONCLUSION: QT abnormalities seem to exist at the point of diagnosis of diabetes and do not appear to change between then and the subsequent cardiac death. Furthermore, the analysis of QT interval is superior to ABPI and the RR interval in identifying diabetic patients at high risk of cardiac death.", "publicationTitle": "Heart", "publisher": "", "place": "", "date": "2005", "volume": "91", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "44–50", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "QT interval abnormalities are often present at diagnosis in diabetes and are better predictors of cardiac death than ankle brachial pressure index and autonomic function tests", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "S3UVJ8G2", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "5TIASBUJ", "version": 54, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/5TIASBUJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/5TIASBUJ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Onat et al.", "parsedDate": "2006", "numChildren": 1 }, "data": { "key": "5TIASBUJ", "version": 54, "itemType": "journalArticle", "title": "Prevalence, incidence, predictors and outcome of type 2 diabetes in Turkey", "creators": [ { "creatorType": "author", "firstName": "A.", "lastName": "Onat" }, { "creatorType": "author", "firstName": "G.", "lastName": "Hergenc" }, { "creatorType": "author", "firstName": "H.", "lastName": "Uyarel" }, { "creatorType": "author", "firstName": "G.", "lastName": "Can" }, { "creatorType": "author", "firstName": "H.", "lastName": "Ozhan" } ], "abstractNote": "OBJECTIVES: To investigate prospectively the incidence, certain predictors and outcomes of type 2 diabetes (DM), as well as to determine its prevalence cross-sectionally, in a representative sample of Turkish men and women.\nMETHODS: Prospective evaluation of 3401 male and female participants (aged 48.2 +/-12 years). Follow-up constituted 19,050 person-years. Individuals with DM were diagnosed with criteria of the American Diabetes Association. Fatal and nonfatal coronary heart disease (CHD) was identified by clinical findings and Minnesota coding of resting electrocardiograms. Cut-points of > or = 95 cm in males and > or = 91 cm in females were selected for abdominal obesity. For prospective evaluations, cases with DM or CHD were excluded.\nRESULTS: Prevalence of DM in Turkish adults was estimated as 2.89 million (11.0% of the population aged > or = 35 years). Over a mean follow-up of 5.9 years, incident DM developed in 223 subjects, yielding an incidence per 1000 person-years of 11.0 in women and 12.4 in men. This corresponded to a 300,000 annual incidence. Following risk parameter levels but not HDL-cholesterol were significantly elevated at baseline in subjects developing DM compared to those without: age (5 years), waist girth (7 cm), blood pressure (12/6 mmHg), apolipoprotein B (7 mg/dl), total cholesterol (14 mg/dl), and fasting triglycerides (only in women, 52 mg/dl). Abdominal obesity (RR 2.61 [95%CI 1.87; 3.63]) and age in both genders, hypertension (RR 1.81 [95%CI 1.10; 2.98]) and low HDL-cholesterol in men alone were significant independent predictors of DM. Diabetes mellitus was a significant and independent predictor of fatal and nonfatal CHD, with a RR of 1.81 (95%CI 1.19; 2.75), after adjustment for sex, age, hypertension, waist circumference, serum total cholesterol and smoking status.\nCONCLUSIONS: The annual incidence of DM in Turkey rises very rapidly, currently stands at 300,000, and, hence, its prevalence also rises correspondingly. Insulin resistance appears to be a weak determinant of DM in Turkish women while abdominal obesity is the main determinant. Multivariately adjusted DM is a significant independent predictor of fatal and nonfatal CHD. These observations emphasize that measures to reverse or stop the \"epidemic\" of abdominal obesity are severely required.", "publicationTitle": "Anadolu Kardiyoloji Dergisi", "publisher": "", "place": "", "date": "2006", "volume": "6", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "314-21", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "17162275", "shortTitle": "Prevalence, incidence, predictors and outcome of type 2 diabetes in Turkey", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "QBUBCPA8", "version": 53, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/QBUBCPA8", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/QBUBCPA8", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Watanabe et al.", "parsedDate": "2010", "numChildren": 0 }, "data": { "key": "QBUBCPA8", "version": 53, "itemType": "journalArticle", "title": "New diagnosis criteria for diabetes with hemoglobin A1c and risks of macro-vascular complications in an urban Japanese cohort: the Suita study", "creators": [ { "creatorType": "author", "firstName": "M.", "lastName": "Watanabe" }, { "creatorType": "author", "firstName": "Y.", "lastName": "Kokubo" }, { "creatorType": "author", "firstName": "A.", "lastName": "Higashiyama" }, { "creatorType": "author", "firstName": "Y.", "lastName": "Ono" }, { "creatorType": "author", "firstName": "A.", "lastName": "Okayama" }, { "creatorType": "author", "firstName": "T.", "lastName": "Okamura" } ], "abstractNote": "The association of the new diagnosis criteria for diabetes adopting hemoglobin A1c, recently proposed by the international expert committee, with macro-vascular complications was tested in a 12-year population-based cohort. The present analysis suggested that this new criteria were applicable to macro-vascular complications in the Japanese. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.", "publicationTitle": "Diabetes Research & Clinical Practice", "publisher": "", "place": "", "date": "2010", "volume": "88", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "e20–3", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "New diagnosis criteria for diabetes with hemoglobin A1c and risks of macro-vascular complications in an urban Japanese cohort: the Suita study", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "PZPJU6EX", "version": 53, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/PZPJU6EX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/PZPJU6EX", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Targher et al.", "parsedDate": "2007", "numChildren": 0 }, "data": { "key": "PZPJU6EX", "version": 53, "itemType": "journalArticle", "title": "Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients", "creators": [ { "creatorType": "author", "firstName": "G.", "lastName": "Targher" }, { "creatorType": "author", "firstName": "L.", "lastName": "Bertolini" }, { "creatorType": "author", "firstName": "S.", "lastName": "Rodella" }, { "creatorType": "author", "firstName": "R.", "lastName": "Tessari" }, { "creatorType": "author", "firstName": "L.", "lastName": "Zenari" }, { "creatorType": "author", "firstName": "G.", "lastName": "Lippi" }, { "creatorType": "author", "firstName": "G.", "lastName": "Arcaro" } ], "abstractNote": "", "publicationTitle": "Diabetes Care", "publisher": "", "place": "", "date": "2007", "volume": "30", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "2119–2121", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Nonalcoholic fatty liver disease is independently associated with an increased incidence of cardiovascular events in type 2 diabetic patients", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "NW2Z6CWX", "version": 53, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/NW2Z6CWX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/NW2Z6CWX", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Sluik et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "NW2Z6CWX", "version": 53, "itemType": "journalArticle", "title": "Physical activity and mortality in individuals with diabetes mellitus: A prospective study and meta-analysis", "creators": [ { "creatorType": "author", "firstName": "D", "lastName": "Sluik" }, { "creatorType": "author", "firstName": "B", "lastName": "Buijsse" }, { "creatorType": "author", "firstName": "R", "lastName": "Muckelbauer" }, { "creatorType": "author", "firstName": "R", "lastName": "Kaaks" }, { "creatorType": "author", "firstName": "B", "lastName": "Teucher" }, { "creatorType": "author", "firstName": "N F", "lastName": "Johnsen" }, { "creatorType": "author", "firstName": "A", "lastName": "Tjonneland" }, { "creatorType": "author", "firstName": "K", "lastName": "Overvad" }, { "creatorType": "author", "firstName": "J N", "lastName": "Ostergaard" }, { "creatorType": "author", "firstName": "P", "lastName": "Amiano" }, { "creatorType": "author", "firstName": "E", "lastName": "Ardanaz" }, { "creatorType": "author", "firstName": "B", "lastName": "Bendinelli" }, { "creatorType": "author", "firstName": "V", "lastName": "Pala" }, { "creatorType": "author", "firstName": "R", "lastName": "Tumino" }, { "creatorType": "author", "firstName": "F", "lastName": "Ricceri" }, { "creatorType": "author", "firstName": "A", "lastName": "Mattiello" }, { "creatorType": "author", "firstName": "A M W", "lastName": "Spijkerman" }, { "creatorType": "author", "firstName": "E M", "lastName": "Monninkhof" }, { "creatorType": "author", "firstName": "A M", "lastName": "May" }, { "creatorType": "author", "firstName": "P W", "lastName": "Franks" }, { "creatorType": "author", "firstName": "P M", "lastName": "Nilsson" }, { "creatorType": "author", "firstName": "P", "lastName": "Wennberg" }, { "creatorType": "author", "firstName": "O", "lastName": "Rolandsson" }, { "creatorType": "author", "firstName": "G", "lastName": "Fagherazzi" }, { "creatorType": "author", "firstName": "M C", "lastName": "Boutron-Ruault" }, { "creatorType": "author", "firstName": "F", "lastName": "Clavel-Chapelon" }, { "creatorType": "author", "firstName": "J M", "lastName": "Huerta Castano" }, { "creatorType": "author", "firstName": "V", "lastName": "Gallo" }, { "creatorType": "author", "firstName": "H", "lastName": "Boeing" }, { "creatorType": "author", "firstName": "U", "lastName": "Nothlings" } ], "abstractNote": "Background: Physical activity (PA) is considered a cornerstone of diabetes mellitus management to prevent complications, but conclusive evidence is lacking. Methods: This prospective cohort study and meta-analysis of existing studies investigated the association between PA and mortality in individuals with diabetes. In the EPIC study (European Prospective Investigation Into Cancer and Nutrition), a cohort was defined of 5859 individuals with diabetes at baseline. Associations of leisure-time and total PA and walking with cardiovascular disease (CVD) and total mortality were studied using multivariable Cox proportional hazards regression models. Fixed- and random-effects meta-analyses of prospective studies published up to December 2010 were pooled with inverse variance weighting. Results: In the prospective analysis, total PA was associated with lower risk of CVD and total mortality. Compared with physically inactive persons, the lowest mortality risk was observed in moderately active persons: hazard ratios were 0.62 (95% CI, 0.49-0.78) for total mortality and 0.51 (95% CI, 0.32-0.81) for CVD mortality. Leisure-time PA was associated with lower total mortality risk, and walking was associated with lower CVD mortality risk. In the meta-analysis, the pooled randomeffects hazard ratio from 5 studies for high vs low total PA and all-cause mortality was 0.60 (95% CI, 0.49-0.73). Conclusions: Higher levels of PA were associated with lower mortality risk in individuals with diabetes. Even those undertaking moderate amounts of activity were at appreciably lower risk for early death compared with inactive persons. These findings provide empirical evidence supporting the widely shared view that persons with diabetes should engage in regular PA. 2012 American Medical Association. All rights reserved.", "publicationTitle": "Archives of Internal Medicine", "publisher": "", "place": "", "date": "2012", "volume": "172", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "1285–1295", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Physical activity and mortality in individuals with diabetes mellitus: A prospective study and meta-analysis", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" }, { "tag": "include" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "9TDZXTAC", "version": 53, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/9TDZXTAC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/9TDZXTAC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Robinson et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "9TDZXTAC", "version": 53, "itemType": "journalArticle", "title": "New Zealand Diabetes Cohort Study cardiovascular risk score for people with Type 2 diabetes: validation in the PREDICT cohort", "creators": [ { "creatorType": "author", "firstName": "T.", "lastName": "Robinson" }, { "creatorType": "author", "firstName": "C. R.", "lastName": "Elley" }, { "creatorType": "author", "firstName": "S.", "lastName": "Wells" }, { "creatorType": "author", "firstName": "E.", "lastName": "Robinson" }, { "creatorType": "author", "firstName": "T.", "lastName": "Kenealy" }, { "creatorType": "author", "firstName": "R.", "lastName": "Pylypchuk" }, { "creatorType": "author", "firstName": "D.", "lastName": "Bramley" }, { "creatorType": "author", "firstName": "B.", "lastName": "Arroll" }, { "creatorType": "author", "firstName": "S.", "lastName": "Crengle" }, { "creatorType": "author", "firstName": "T.", "lastName": "Riddell" }, { "creatorType": "author", "firstName": "S.", "lastName": "Ameratunga" }, { "creatorType": "author", "firstName": "P.", "lastName": "Metcalf" }, { "creatorType": "author", "firstName": "P. L.", "lastName": "Drury" } ], "abstractNote": "INTRODUCTION: New Zealand (NZ) guidelines recommend treating people for cardiovascular disease (CVD) risk on the basis of five-year absolute risk using a NZ adaptation of the Framingham risk equation. A diabetes-specific Diabetes Cohort Study (DCS) CVD predictive risk model has been developed and validated using NZ Get Checked data.\nAIM: To revalidate the DCS model with an independent cohort of people routinely assessed using PREDICT, a web-based CVD risk assessment and management programme.\nMETHODS: People with Type 2 diabetes without pre-existing CVD were identified amongst people who had a PREDICT risk assessment between 2002 and 2005. From this group we identified those with sufficient data to allow estimation of CVD risk with the DCS models. We compared the DCS models with the NZ Framingham risk equation in terms of discrimination, calibration, and reclassification implications.\nRESULTS: Of 3044 people in our study cohort, 1829 people had complete data and therefore had CVD risks calculated. Of this group, 12.8% (235) had a cardiovascular event during the five-year follow-up. The DCS models had better discrimination than the currently used equation, with C-statistics being 0.68 for the two DCS models and 0.65 for the NZ Framingham model.\nDISCUSSION: The DCS models were superior to the NZ Framingham equation at discriminating people with diabetes who will have a cardiovascular event. The adoption of a DCS model would lead to a small increase in the number of people with diabetes who are treated with medication, but potentially more CVD events would be avoided.", "publicationTitle": "Journal of Primary Health Care", "publisher": "", "place": "", "date": "2012", "volume": "4", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "181-8", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "New Zealand Diabetes Cohort Study cardiovascular risk score for people with Type 2 diabetes: validation in the PREDICT cohort", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "not found" } ], "collections": [ "6THA6UHM", "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } }, { "key": "TXG7XNKS", "version": 53, "library": { "type": "group", "id": 310898, "name": "cvd fulltext search", "links": { "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/310898/items/TXG7XNKS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/cvd_fulltext_search/items/TXG7XNKS", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2047911, "username": "V.Lutterrmann", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/v.lutterrmann", "type": "text/html" } } }, "creatorSummary": "Parving et al.", "parsedDate": "2006", "numChildren": 0 }, "data": { "key": "TXG7XNKS", "version": 53, "itemType": "journalArticle", "title": "Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: A global perspective", "creators": [ { "creatorType": "author", "firstName": "H H", "lastName": "Parving" }, { "creatorType": "author", "firstName": "J B", "lastName": "Lewis" }, { "creatorType": "author", "firstName": "M", "lastName": "Ravid" }, { "creatorType": "author", "firstName": "G", "lastName": "Remuzzi" }, { "creatorType": "author", "firstName": "L G", "lastName": "Hunsicker" } ], "abstractNote": "We described the characteristics in a referred cohort of type II diabetic patients in the Developing Education on Microalbuminuria for Awareness of renal and cardiovascular risk in Diabetes study evaluating the global prevalence and determinants of microalbuminuria (MA). A cross-sectional study evaluating 32 208 type II diabetic patients without known albuminuria from 33 countries was performed. Overall, 8057 patients were excluded, either because of prior known proteinuria or non-diabetic nephropathy (3670), or because of invalid urine collections (4387). One single random urinary albumin/creatinine ratio was obtained in 24 151 patients (75%). The overall global prevalence of normo-, micro-, and macroalbuminuria was 51, 39, and 10%, respectively. The Asian and Hispanic patients had the highest prevalence of a raised urinary albumin/creatinine ratio (55%) and Caucasians the lowest (40.6), P<0.0001. HbA1c, systolic blood pressure (BP), ethnicity, retinopathy, duration of diabetes, kidney function, body height, and smoking were all independent risk factors of MA, P<0.0001. Estimated glomerular filtration rate was below 60 ml/min/1.73 m2 in 22% of the 11 573 patients with available data. Systolic BP below 130 mmHg was found in 33 and 43% had an HbA1c below 7%. The frequency of patients receiving aspirin was 32%, statins 29%, and BP-lowering therapy 63%. A high prevalence globally of MA and reduced kidney function, both conditions associated with enhanced renal and cardiovascular risk, was detected in type II diabetic patients without prior known nephropathy. Early detection, monitoring of vascular complications, and more aggressive multifactorial treatment aiming at renal and vascular protection are urgently needed. 2006 International Society of Nephrology.", "publicationTitle": "Kidney International", "publisher": "", "place": "", "date": "2006", "volume": "69", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "2057–2063", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "Prevalence and risk factors for microalbuminuria in a referred cohort of type II diabetic patients: A global perspective", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "found and saved" } ], "collections": [ "ZSIDP3U5" ], "relations": {}, "dateAdded": "2014-12-01T10:19:23Z", "dateModified": "2014-12-01T10:19:23Z" } } ]