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"creators": [ { "creatorType": "author", "firstName": "C. G", "lastName": "Przybycin" }, { "creatorType": "author", "firstName": "R. J", "lastName": "Kurman" }, { "creatorType": "author", "firstName": "B. M", "lastName": "Ronnett" }, { "creatorType": "author", "firstName": "I. 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R", "lastName": "Creasy" }, { "creatorType": "author", "firstName": "E. D.", "lastName": "Alberman" } ], "abstractNote": "A study of 2620 pregnancies ending in spontaneous abortion revealed\na CNS defect in 3.6% of embryos and fetuses, and 3% of all complete conceptuses.\nThe type of malformation observed varied with the gestational age at\nexpulsion, encephaloceles being predominant in earlier specimens, while more\ntypical anencephalus and spina bifida were more common among later abortions.\nChromosome abnormalities were found in 40% of abortuses with CNS defects,\nbut were almost entirely confined to those which were still at the embryonic stage of\ndevelopment. 53% of the latter were chromosomally abnormal, which is the same\nas the proportion found among embryos without a CNS malformation.\nUsing published life-tables of recognized pregnancies it was estimated that the\nprevalence of anencephalus, spina bifida, or related malformation (other than\nhydrocephalus), without a chromosome anomaly, is 5.3 per thousand conceptuses at\nthe beginning of the eighth week of gestation. By comparing this with the prevalence\nin total births, it was further estimated that only 24% ofthese are born alive,\nwith 54% aborting spontaneously and 22% being stillborn.", "publicationTitle": "Journal of medical genetics", "publisher": "", "place": "", "date": "1976", "volume": "13", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "9", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1468-6244", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "Google Scholar", "callNumber": "0090", "rights": "", "extra": "", "tags": [], "collections": [ "93H5UQZ4" ], "relations": {}, "dateAdded": "2010-11-09T11:53:56Z", "dateModified": "2013-01-13T11:13:37Z" } }, { "key": "QG7TJU3M", "version": 2, "library": { "type": "group", "id": 30944, "name": "pathology_residents", "links": { "alternate": { "href": "https://www.zotero.org/groups/pathology_residents", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/30944/items/QG7TJU3M", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/pathology_residents/items/QG7TJU3M", "type": "text/html" } }, "meta": { "createdByUser": { "id": 109565, "username": "jurgenhench", "name": "Jürgen Hench", "links": { "alternate": { "href": "https://www.zotero.org/jurgenhench", "type": "text/html" } } }, "lastModifiedByUser": { "id": 1180829, "username": "atayu", "name": "Atay Uludokumacı", "links": { "alternate": { "href": "https://www.zotero.org/atayu", "type": "text/html" } } }, "creatorSummary": "Ferrer et al.", "parsedDate": "2008", "numChildren": 0 }, "data": { "key": "QG7TJU3M", "version": 2, "itemType": "journalArticle", "title": "Argyrophilic grain disease", "creators": [ { "creatorType": "author", "firstName": "I.", "lastName": "Ferrer" }, { "creatorType": "author", "firstName": "G.", "lastName": "Santpere" }, { "creatorType": "author", "firstName": "F. W.", "lastName": "van Leeuwen" } ], "abstractNote": "", "publicationTitle": "Brain", "publisher": "", "place": "", "date": "01/2008", "volume": "131", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "1416-1432", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Brain", "DOI": "10.1093/brain/awm305", "citationKey": "", "url": "http://www.brain.oxfordjournals.org/cgi/doi/10.1093/brain/awm305", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0006-8950", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "0032", "rights": "", "extra": "", "tags": [], "collections": [ "MKTCK6GR" ], "relations": {}, "dateAdded": "2010-11-09T11:53:43Z", "dateModified": "2013-01-13T11:13:36Z" } }, { "key": "MWM357J2", "version": 2, "library": { "type": "group", "id": 30944, "name": "pathology_residents", "links": { "alternate": { "href": "https://www.zotero.org/groups/pathology_residents", "type": 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