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Objetivos: Avaliar o efeito hipoglicemiante da B. forficata em pacientes com diabetes tipo 2. Métodos: Na primeira coleta (coleta 1), 49 indivíduos foram submetidos à avaliação antropométrica e glicêmi...", "websiteTitle": "ConScientiae Saúde", "websiteType": "", "date": "2014", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.redalyc.org/resumen.oa?id=92930146009", "accessDate": "2015-03-27T20:51:58Z", "shortTitle": "", "language": "pt", "rights": "", "extra": "", "tags": [ { "tag": "Blood Glucose", "type": 1 }, { "tag": "Fitoterápicos", "type": 1 }, { "tag": "Glicemia", "type": 1 }, { "tag": "Hemoglobin A glycosylated", "type": 1 }, { "tag": "Hemoglobina A glicosilada", "type": 1 }, { "tag": "Phytotherapeutic drugs", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2015-03-27T20:51:58Z", "dateModified": "2015-03-27T20:51:58Z" } }, { "key": "NET4QUFN", "version": 67, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/NET4QUFN", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/NET4QUFN", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Gobierno de Chile", "parsedDate": "2009", "numChildren": 0 }, "data": { "key": "NET4QUFN", "version": 67, "itemType": "document", "title": "Manual de toma de muestras de laboratorio central", "creators": [ { "creatorType": "author", "name": "Gobierno de Chile" } ], "abstractNote": "", "type": "", "date": "Agosto 2009", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.hsalvador.cl/documentos/Manual_toma_de_muestra.pdf", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "Español", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Examenes laboratorio" }, { "tag": "toma de muestras" } ], "collections": [], "relations": {}, "dateAdded": "2015-02-09T03:10:08Z", "dateModified": "2015-02-09T03:12:05Z" } }, { "key": "ASKUZR3I", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/ASKUZR3I", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/ASKUZR3I", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "ASKUZR3I", "version": 66, "itemType": "document", "title": "", "creators": [], "abstractNote": "", "type": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2015-01-28T13:50:13Z", "dateModified": "2015-01-28T13:50:13Z" } }, { "key": "ZSFAV6T6", "version": 65, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/ZSFAV6T6", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/ZSFAV6T6", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "creatorSummary": "Makeli Garibotti and Cleusa Bona", "numChildren": 0 }, "data": { "key": "ZSFAV6T6", "version": 65, "itemType": "journalArticle", "title": "Análisis morfologico comparativo de hoja de Bauhinia Forficata link y B. Variegata Linn.", "creators": [ { "creatorType": "author", "name": "Makeli Garibotti" }, { "creatorType": "author", "name": "Cleusa Bona" } ], "abstractNote": "", "publicationTitle": "", "publisher": "", "place": "", "date": "", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "http://www.scielo.br/pdf/abb/v23n1/v23n1a22.pdf", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "bauhinia forficata" }, { "tag": "morfología bauhinia forficata" } ], "collections": [], "relations": {}, "dateAdded": "2014-12-13T21:18:54Z", "dateModified": "2014-12-13T21:20:57Z" } }, { "key": "5RFW5NJG", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/5RFW5NJG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/5RFW5NJG", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "5RFW5NJG", "version": 66, "itemType": "dictionaryEntry", "title": "Real Academia Española", "creators": [], "abstractNote": "", "dictionaryTitle": "Real Academia Española", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "", "publisher": "", "place": "", "pages": "", "ISBN": "", "DOI": "", "citationKey": "", "url": "http://www.rae.es/", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-12-10T20:34:11Z", "dateModified": "2014-12-10T20:35:06Z" } }, { "key": "UPB5NK42", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/UPB5NK42", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/UPB5NK42", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "UPB5NK42", "version": 66, "itemType": "webpage", "title": "MedlinePlus - Health Information from the National Library of Medicine", "creators": [], "abstractNote": "Find information on health conditions, wellness issues, and more in easy-to-read language on MedlinePlus, the up-to-date, trusted health information site from the NIH and the National Library of Medicine.", "websiteTitle": "", "websiteType": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.nlm.nih.gov/medlineplus/", "accessDate": "2014-12-10T20:30:08Z", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-12-10T20:30:08Z", "dateModified": "2014-12-10T20:30:08Z" } }, { "key": "E4KGFUNX", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/E4KGFUNX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/E4KGFUNX", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "da Cunha et al.", "parsedDate": "2010", "numChildren": 2 }, "data": { "key": "E4KGFUNX", "version": 66, "itemType": "journalArticle", "title": "Hypoglycemic activity of dried extracts of Bauhinia forficata Link", "creators": [ { "creatorType": "author", "firstName": "A. M. da", "lastName": "da Cunha" }, { "creatorType": "author", "firstName": "S.", "lastName": "Menon" }, { "creatorType": "author", "firstName": "R.", "lastName": "Menon" }, { "creatorType": "author", "firstName": "A. G.", "lastName": "Couto" }, { "creatorType": "author", "firstName": "C.", "lastName": "Bürger" }, { "creatorType": "author", "firstName": "M. W.", "lastName": "Biavatti" } ], "abstractNote": "Leaves of the pantropical genus Bauhinia (Fabaceae) are known popularly as cow's foot, due to their unique characteristic bilobed aspect. The species Bauhinia forficata (Brazilian Orchid-tree) is widely used in folk medicine as an antidiabetic. The present work investigates the hypoglycemic activity of the dried extracts of Bauhinia forficata leaves in vivo, as well as the influence of the drying and granulation processes on this activity. The fluid extract was dried to generate oven-dried (ODE), spray-dried (SDE) and wet granulation (WGE) extracts, with the aid of colloidal silicon dioxide and/or cellulose:lactose mixture. The dried extracts were characterized by spectrophotometric, chromatographic and photo microscopy image analysis. 200 mg/kg body wt., p.o. of each dried product were administered orally to male Wistar rats over 7 days old, for biomonitoring of the hypoglycemic activity profile. The effect of the extracts was studied in STZ-induced diabetic rats. After 7 days of treatment, fasting glucose was determined, and the livers were removed, dried on tissue paper, weighed, and stored at -20°C to estimate hepatic glycogen. Our results show that spray-drying or oven-drying processes applied to B. forficata extracts did not significantly alter its flavonoid profile or its hypoglycemic activity. Indeed, the dried extracts of B. forficata act differently from glibenclamide. Despite the lower active content in WGE, because of the higher concentration of adjuvants, the use of the granulation process improved the manufacturing properties of the ODE, making this material more appropriate for use in tablets or capsules.", "publicationTitle": "Phytomedicine", "publisher": "", "place": "", "date": "2010", "volume": "17", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "37–41", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1016/j.phymed.2009.06.007", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0944711309001676", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "Microsoft Academic Search", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Diabetic Rat", "type": 1 }, { "tag": "Folk Medicine", "type": 1 }, { "tag": "Image Analysis", "type": 1 }, { "tag": "Process Improvement", "type": 1 }, { "tag": "Spray Drying", "type": 1 }, { "tag": "wistar rat", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:45:30Z", "dateModified": "2014-12-10T20:25:43Z" } }, { "key": "5J4I6UQ4", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/5J4I6UQ4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/5J4I6UQ4", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Curcio et al.", "parsedDate": "2012-07", "numChildren": 1 }, "data": { "key": "5J4I6UQ4", "version": 66, "itemType": "journalArticle", "title": "Hypoglycemic effects of an aqueous extract of Bauhinia forficata on the salivary glands of diabetic mice", "creators": [ { "creatorType": "author", "firstName": "Sergio Augusto Fudaba", "lastName": "Curcio" }, { "creatorType": "author", "firstName": "Luciana Francine Bocchi", "lastName": "Stefan" }, { "creatorType": "author", "firstName": "Bruno Azevedo", "lastName": "Randi" }, { "creatorType": "author", "firstName": "Marco Antonio", "lastName": "Dias" }, { "creatorType": "author", "firstName": "Rodrigo Eduardo", "lastName": "da Silva" }, { "creatorType": "author", "firstName": "Eduardo José", "lastName": "Caldeira" } ], "abstractNote": "The objective of this study was to evaluate the salivary glands in diabetic mice, analyzing alterations in the secretory epithelium and interactions with the stromal compartment acquired during a prolonged period of treatment with Bauhinia forficata extract. Female mice were divided into two groups: Nonobese diabetic (NOD) mice treated with Bauhinia forficata (I), and NOD mice not treated with the hypoglycemic agent (II). After treatment, the salivary glands were collected for analysis by transmitted and polarized light microscopy, complemented by three-dimensional analysis of these tissues. The results showed weight loss in animals of group II and weight recovery in treated animals. Glucose levels were elevated in group II, but declined in group I. In the two groups, the salivary glands were characterized by involution of the secretory epithelium, presence of an inflammatory infiltrate and an increase of extracellular fibrillar components. It can be concluded that treatment with Bauhinia forficata reduced glucose levels and contributed to weight recovery in treated animals. However, the observation of tissue destructuring and compromised epithelial-stromal interactions, with consequent impairment of glandular function, demonstrates that Bauhinia forficata exerts an effect on the recovery of body metabolism but this improvement does not influence in the tissue recovery.", "publicationTitle": "Pakistan Journal of Pharmaceutical Sciences", "publisher": "", "place": "", "date": "Jul 2012", "volume": "25", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "493-499", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Pak J Pharm Sci", "DOI": "", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22713933", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1011-601X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22713933", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Bauhinia", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Diabetes Mellitus", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Hypoglycemic Agents", "type": 1 }, { "tag": "Mice", "type": 1 }, { "tag": "Mice, Inbred NOD", "type": 1 }, { "tag": "Phytotherapy", "type": 1 }, { "tag": "Plant Extracts", "type": 1 }, { "tag": "Salivary Glands", "type": 1 }, { "tag": "Weight Loss", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:38:35Z", "dateModified": "2014-12-10T20:21:09Z" } }, { "key": "NE6UJ25K", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/NE6UJ25K", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/NE6UJ25K", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "de Sousa et al.", "parsedDate": "2004-05", "numChildren": 1 }, "data": { "key": "NE6UJ25K", "version": 66, "itemType": "journalArticle", "title": "Hypoglycemic effect and antioxidant potential of kaempferol-3,7-O-(alpha)-dirhamnoside from Bauhinia forficata leaves", "creators": [ { "creatorType": "author", "firstName": "Eliandra", "lastName": "de Sousa" }, { "creatorType": "author", "firstName": "Leila", "lastName": "Zanatta" }, { "creatorType": "author", "firstName": "Ilana", "lastName": "Seifriz" }, { "creatorType": "author", "firstName": "Tânia Beatriz", "lastName": "Creczynski-Pasa" }, { "creatorType": "author", "firstName": "Moacir Geraldo", "lastName": "Pizzolatti" }, { "creatorType": "author", "firstName": "Bruno", "lastName": "Szpoganicz" }, { "creatorType": "author", "firstName": "Fátima Regina Mena Barreto", "lastName": "Silva" } ], "abstractNote": "In vivo and in vitro treatments were carried out to investigate the effects of kaempferol-3,7-O-(alpha)-dirhamnoside (kaempferitrin), a major flavonoid compound of the n-butanol fraction from Bauhiniaforficata leaves, on serum glucose levels, as well as its antioxidant potential. Oral administration of kaempferitrin led to a significant hypoglycemic effect in normal and in alloxan-induced diabetic rats. In normal rats, blood glucose lowering was observed only with the higher dose of kaempferitrin (200 mg/kg) at 1 h after treatment. However, the hypoglycemic effect of kaempferitrin in diabetic rats was evident at all doses tested (50, 100, and 200 mg/kg), and this profile was maintained throughout the period studied for both higher doses. Additionally, in glucose-fed hyperglycemic normal rats, the kaempferitrin failed to decrease blood glucose levels. In vitro antioxidant properties or action against reactive oxygen species of this compound was also evaluated. The compound showed high reactivity with 1,1-diphenyl-2-picryl hydrazyl (DPPH), IC(50) of 84.0 +/- 7.8 microM, inhibited myeloperoxidase activity with K(0.5) = 86 +/- 9.9 microM, and decreased lipid peroxidation, induced by ascorbyl radical either in microsomes or in asolectin and phosphatidylcholine liposomes, with IC(50)'s of 320 +/- 14.1, 223 +/- 8.3, and 112 +/- 8.8 microM, respectively.", "publicationTitle": "Journal of Natural Products", "publisher": "", "place": "", "date": "May 2004", "volume": "67", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "829-832", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J. Nat. Prod.", "DOI": "10.1021/np030513u", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/15165145", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0163-3864", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 15165145", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Antioxidants", "type": 1 }, { "tag": "Bauhinia", "type": 1 }, { "tag": "Biphenyl Compounds", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Brazil", "type": 1 }, { "tag": "Diabetes Mellitus, Experimental", "type": 1 }, { "tag": "Dose-Response Relationship, Drug", "type": 1 }, { "tag": "Glucose Tolerance Test", "type": 1 }, { "tag": "Hypoglycemic Agents", "type": 1 }, { "tag": "Inhibitory Concentration 50", "type": 1 }, { "tag": "Kaempferols", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Molecular Structure", "type": 1 }, { "tag": "Picrates", "type": 1 }, { "tag": "Plant Leaves", "type": 1 }, { "tag": "Plants, Medicinal", "type": 1 }, { "tag": "Rats", "type": 1 }, { "tag": "Rats, Wistar", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:39:26Z", "dateModified": "2014-12-10T20:19:45Z" } }, { "key": "EDTUZV4Z", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/EDTUZV4Z", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/EDTUZV4Z", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "EDTUZV4Z", "version": 66, "itemType": "document", "title": "Encuesta Nacional de Salud ENS 2009 - 2010. Comparación Region de Valparaíso y pais", "creators": [], "abstractNote": "", "type": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://seremi5.redsalud.gob.cl/wrdprss_minsal/wp-content/uploads/2012/01/Epi-ENS.pdf", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "Pág. 30-33", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:27:30Z", "dateModified": "2014-12-10T20:07:16Z" } }, { "key": "VIDHAWV4", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/VIDHAWV4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/VIDHAWV4", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "O. Cartaya and Inés Reynaldo", "parsedDate": "2001", "numChildren": 0 }, "data": { "key": "VIDHAWV4", "version": 66, "itemType": "journalArticle", "title": "Flavonoides: Caracteristicas Quimicas y Aplicaciones", "creators": [ { "creatorType": "author", "name": "O. Cartaya" }, { "creatorType": "author", "name": "Inés Reynaldo" } ], "abstractNote": "En este articulo se muestran las principales ca-\nracterísticas estructurales de los flavonoides y sus métodos de\nseparación e identificación. Estos compuestos presentan dife-\nrentes funciones en las plantas, como atrayentes de animales\no como agentes protectores; además, algunos flavonoides pre-\nsentan actividad antioxidante, lo cual está relacionado con la\nsalud humana", "publicationTitle": "Red de revistas cientificas de america latina, el caribe, españa y portugal", "publisher": "", "place": "", "date": "2001", "volume": "22", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "http://www.redalyc.org/pdf/1932/193215009001.pdf", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "Español", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "flavonoides" }, { "tag": "metabolitos" }, { "tag": "propiedades medicinales" } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:22:26Z", "dateModified": "2014-12-10T19:50:28Z" } }, { "key": "KCNF4EH9", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/KCNF4EH9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/KCNF4EH9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Dr. Jesús Miguel Hernández-Guijo", "parsedDate": "2008", "numChildren": 0 }, "data": { "key": "KCNF4EH9", "version": 66, "itemType": "document", "title": "Toxinas naturales de origen vegetal", "creators": [ { "creatorType": "author", "name": "Dr. Jesús Miguel Hernández-Guijo" } ], "abstractNote": "", "type": "", "date": "2008", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "https://www.uam.es/departamentos/medicina/farmacologia/especifica/ToxAlim/ToxAlim_L9.pdf", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "toxicología alimentaria" } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:18:22Z", "dateModified": "2014-12-10T19:48:31Z" } }, { "key": "FTW6HKAF", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/FTW6HKAF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/FTW6HKAF", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Dr. J. Andrés Valsconcellos", "parsedDate": "1998", "numChildren": 0 }, "data": { "key": "FTW6HKAF", "version": 66, "itemType": "journalArticle", "title": "Alimentos funcionales. Conceptos y beneficios para la salud", "creators": [ { "creatorType": "author", "name": "Dr. J. Andrés Valsconcellos" } ], "abstractNote": "", "publicationTitle": "", "publisher": "", "place": "", "date": "1998", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "The World of Food Science", "DOI": "", "citationKey": "", "url": "http://www.madrimasd.org/cienciaysociedad/ateneo/dossier/alimentos_funcionales/worldfoodscience/alimentosfuncionales.htm", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "alimentos funcionales" } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:12:28Z", "dateModified": "2014-12-10T19:32:09Z" } }, { "key": "QBHQZVI5", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/QBHQZVI5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/QBHQZVI5", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "lastModifiedByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "parsedDate": "1996", "numChildren": 0 }, "data": { "key": "QBHQZVI5", "version": 66, "itemType": "document", "title": "Uso industrial de plantas aromáticas y medicinales", "creators": [], "abstractNote": "", "type": "", "date": "1996 - 2003", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://ocw.upm.es/ingenieria-agroforestal/uso-industrial-de-plantas-aromaticas-y-medicinales/contenidos/material-de-clase/tema7.pdf", "accessDate": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "planta aromática" } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T17:55:34Z", "dateModified": "2014-12-10T19:21:58Z" } }, { "key": "CFV46JJD", "version": 66, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/CFV46JJD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/CFV46JJD", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Gobierno de Chile", "numChildren": 0 }, "data": { "key": "CFV46JJD", "version": 66, "itemType": "book", "title": "MHT, Medicamentos Herbarios Tradicionales", "creators": [ { "creatorType": "author", "name": "Gobierno de Chile" } ], "abstractNote": "", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "", "publisher": "", "place": "", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "numPages": "", "ISBN": "", "DOI": "", "citationKey": "", "url": "http://web.minsal.cl/sites/default/files/files/Libro%20MHT%202010.pdf", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-12-10T19:02:02Z", "dateModified": "2014-12-10T19:04:19Z" } }, { "key": "U797HSG3", "version": 59, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/U797HSG3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/U797HSG3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "creatorSummary": "Russo et al.", "parsedDate": "1990", "numChildren": 1 }, "data": { "key": "U797HSG3", "version": 59, "itemType": "journalArticle", "title": "Clinical trial of Myrcia uniflora and Bauhinia forficata leaf extracts in normal and diabetic patients", "creators": [ { "creatorType": "author", "firstName": "E. M.", "lastName": "Russo" }, { "creatorType": "author", "firstName": "A. A.", "lastName": "Reichelt" }, { "creatorType": "author", "firstName": "J. R.", "lastName": "De-Sá" }, { "creatorType": "author", "firstName": "R. P.", "lastName": "Furlanetto" }, { "creatorType": "author", "firstName": "R. C.", "lastName": "Moisés" }, { "creatorType": "author", "firstName": "T. S.", "lastName": "Kasamatsu" }, { "creatorType": "author", "firstName": "A. R.", "lastName": "Chacra" } ], "abstractNote": "1. Myrcia uniflora and Bauhinia forficata were compared with placebo for their hypoglycemic effect in randomized cross-over double-blind studies in 2 groups of normal subjects (10 subjects each) and 2 groups of Type II diabetic patients (18 in the M. uniflora group and 16 in the B. forficata group). The protocol with each plant lasted 56 days. 2. After the ingestion of infusions of 3 g leaves/day of M. uniflora and B. forficata leaves, no acute or chronic effects on plasma glucose levels or glycated hemoglobin were found in either group. However, plasma insulin levels in the diabetic group were lower after M. uniflora than after placebo. 3. Among other clinical parameters tested, a statistically significant difference was found only in the alkaline phosphatase level after placebo compared with that after M. uniflora in the normal group. 4. There were no differences in any clinical parameters after the use of placebo or of B. forficata. 5. We conclude that infusions prepared from the leaves of M. uniflora or B. forficata have no hypoglycemic effect on normal subjects or Type II diabetic patients.", "publicationTitle": "Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas / Sociedade Brasileira De Biofísica ... [et Al.]", "publisher": "", "place": "", "date": "1990", "volume": "23", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "11-20", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Braz. J. Med. Biol. Res.", "DOI": "", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/2201413", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0100-879X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 2201413", "tags": [ { "tag": "Adult", "type": 1 }, { "tag": "Aged", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Clinical Trials as Topic", "type": 1 }, { "tag": "Diabetes Mellitus, Type 2", "type": 1 }, { "tag": "Double-Blind Method", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Insulin", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Plant Extracts", "type": 1 }, { "tag": "Plants, Medicinal", "type": 1 }, { "tag": "Random Allocation", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:52:06Z", "dateModified": "2014-12-10T18:52:20Z" } }, { "key": "QKKC42F5", "version": 59, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/QKKC42F5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/QKKC42F5", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/303353/items/U797HSG3", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } } }, "data": { "key": "QKKC42F5", "version": 59, "parentItem": "U797HSG3", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-12-10T18:52:06Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/2201413", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-12-10T18:52:06Z", "dateModified": "2014-12-10T18:52:06Z" } }, { "key": "2D7KH2VC", "version": 58, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/2D7KH2VC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/2D7KH2VC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } }, "creatorSummary": "Salgueiro et al.", "parsedDate": "2013-06-21", "numChildren": 1 }, "data": { "key": "2D7KH2VC", "version": 58, "itemType": "journalArticle", "title": "The influence of Bauhinia forficata Link subsp. pruinosa tea on lipid peroxidation and non-protein SH groups in human erythrocytes exposed to high glucose concentrations", "creators": [ { "creatorType": "author", "firstName": "Andréia C. F.", "lastName": "Salgueiro" }, { "creatorType": "author", "firstName": "Carina Q.", "lastName": "Leal" }, { "creatorType": "author", "firstName": "Matheus C.", "lastName": "Bianchini" }, { "creatorType": "author", "firstName": "Ianeli O.", "lastName": "Prado" }, { "creatorType": "author", "firstName": "Andreas S. L.", "lastName": "Mendez" }, { "creatorType": "author", "firstName": "Robson L.", "lastName": "Puntel" }, { "creatorType": "author", "firstName": "Vanderlei", "lastName": "Folmer" }, { "creatorType": "author", "firstName": "Félix A.", "lastName": "Soares" }, { "creatorType": "author", "firstName": "Daiana S.", "lastName": "Avila" }, { "creatorType": "author", "firstName": "Gustavo O.", "lastName": "Puntel" } ], "abstractNote": "ETHNOPHARMACOLOGICAL RELEVANCE: Bauhinia forficata (BF) has been traditionally used as tea in folk medicine of Brazil for treatment of Diabetes mellitus (DM).\nAIM OF THE STUDY: To evaluate the effects of BF leaf tea on markers of oxidative damage and antioxidant levels in an experimental model of hyperglycemia in human erythrocytes in vitro.\nMATERIALS AND METHODS: Human erythrocytes were incubated with high glucose concentrations or glucose and BF tea for 24h and 48h. After incubation lipid peroxidation and non-protein SH levels were analyzed. Moreover, quantification of polyphenols and flavonoids, iron chelating property, scavenging of DPPH, and prevention of lipid peroxidation in isolated lipids were also assessed.\nRESULTS: A significant amount of polyphenols and flavonoids was observed. The main components found by LC-MS analysis were quercetin-3-O-(2-rhamnosyl) rutinoside, kaempferol-3-O-(2-rhamnosyl) rutinoside, quercetin-3-O-rutinoside and kaempferol-3-O-rutinoside. BF tea presents important antioxidant and chelating properties. Moreover, BF tea was effective to increase non-protein SH levels and reduce lipid peroxidation induced by high glucose concentrations in human erythrocytes.\nCONCLUSION: The antioxidant effects of BF tea could be related to the presence of different phenolic and flavonoids components. We believe that these components can be responsible to protect human erythrocytes exposed to high glucose concentrations against oxidative damage.", "publicationTitle": "Journal of Ethnopharmacology", "publisher": "", "place": "", "date": "Jun 21, 2013", "volume": "148", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "81-87", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Ethnopharmacol", "DOI": "10.1016/j.jep.2013.03.070", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0378874113002407", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1872-7573", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 23567030", "tags": [ { "tag": "Antioxidants", "type": 1 }, { "tag": "Bauhinia", "type": 1 }, { "tag": "Beverages", "type": 1 }, { "tag": "Cells, Cultured", "type": 1 }, { "tag": "Erythrocytes", "type": 1 }, { "tag": "Flavonoids", "type": 1 }, { "tag": "Glucose", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Lipid Peroxidation", "type": 1 }, { "tag": "Phenols", "type": 1 }, { "tag": "Plant Leaves", "type": 1 }, { "tag": "Sulfhydryl Compounds", "type": 1 }, { "tag": "Thiobarbituric Acid Reactive Substances", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:40:02Z", "dateModified": "2014-12-10T18:50:13Z" } }, { "key": "TMRA3CRH", "version": 60, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/TMRA3CRH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/TMRA3CRH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Santos et al.", "parsedDate": "2012", "numChildren": 0 }, "data": { "key": "TMRA3CRH", "version": 60, "itemType": "journalArticle", "title": "Uso empírico de plantas medicinais para tratamento de diabetes", "creators": [ { "creatorType": "author", "firstName": "M. M.", "lastName": "Santos" }, { "creatorType": "author", "firstName": "M. G. S.", "lastName": "Nunes" }, { "creatorType": "author", "firstName": "R. D.", "lastName": "Martins" } ], "abstractNote": "", "publicationTitle": "Revista Brasileira de Plantas Medicinais", "publisher": "", "place": "", "date": "00/2012", "volume": "14", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "327-334", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1590/S1516-05722012000200012", "citationKey": "", "url": "http://www.scielo.br/scielo.php?script=sci_abstract&pid=S1516-05722012000200012&lng=en&nrm=iso&tlng=pt", "accessDate": "2014-12-10T18:49:36Z", "PMID": "", "PMCID": "", "ISSN": "1516-0572", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "SciELO", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:49:36Z", "dateModified": "2014-12-10T18:49:36Z" } }, { "key": "9CEKA4U3", "version": 60, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/9CEKA4U3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/9CEKA4U3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Silva et al.", "parsedDate": "2002-11", "numChildren": 1 }, "data": { "key": "9CEKA4U3", "version": 60, "itemType": "journalArticle", "title": "Acute effect of Bauhinia forficata on serum glucose levels in normal and alloxan-induced diabetic rats", "creators": [ { "creatorType": "author", "firstName": "Fátima Regina Mena Barreto", "lastName": "Silva" }, { "creatorType": "author", "firstName": "Bruno", "lastName": "Szpoganicz" }, { "creatorType": "author", "firstName": "Moacir Geraldo", "lastName": "Pizzolatti" }, { "creatorType": "author", "firstName": "Maria Alice Vieira", "lastName": "Willrich" }, { "creatorType": "author", "firstName": "Eliandra", "lastName": "de Sousa" } ], "abstractNote": "Experimental diabetes was used to study the acute effect of the n-butanol fraction of Bauhinia forficata Link (Leguminosae) (BF) leaves on the serum glucose levels of rats. Body weight was measured on the day of diabetes induction and on the day of the experiment. Levels of glucose were determined at different doses and times following treatment with BF or with vehicle in normal, diabetic and hyperglycemic normal rats. Oral administration of n-BuOH fraction led to a significant blood glucose-lowering effect in normal and diabetic rats. However, in glucose-fed hyperglycemic normal rats, the maximum dose of this fraction failed to decrease blood glucose levels. The hypoglycemic effect was observed at doses of 500 and 600 mg/kg after 1 and 2 h treatment respectively, in normal rats. The maximum effect of BF was detected at 1 h with 800 mg/kg in diabetic animals and this profile was maintained for the next 3 h. Treatment of normal and alloxan-induced diabetic rats with BF decreased glucose levels, while this fraction was devoid of hypoglycemic effect in glucose-fed hyperglycemic normal rats.", "publicationTitle": "Journal of Ethnopharmacology", "publisher": "", "place": "", "date": "Nov 2002", "volume": "83", "issue": "1-2", "section": "", "partNumber": "", "partTitle": "", "pages": "33-37", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Ethnopharmacol", "DOI": "", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/12413705", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0378-8741", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 12413705", "tags": [ { "tag": "Alloxan", "type": 1 }, { "tag": "Animals", "type": 1 }, { "tag": "Bauhinia", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Diabetes Mellitus, Experimental", "type": 1 }, { "tag": "Dose-Response Relationship, Drug", "type": 1 }, { "tag": "Glucose Tolerance Test", "type": 1 }, { "tag": "Hypoglycemic Agents", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Phytotherapy", "type": 1 }, { "tag": "Plant Extracts", "type": 1 }, { "tag": "Plant Leaves", "type": 1 }, { "tag": "Rats", "type": 1 }, { "tag": "Rats, Wistar", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:47:29Z", "dateModified": "2014-12-10T18:47:50Z" } }, { "key": "5IS36IMT", "version": 60, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/5IS36IMT", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/5IS36IMT", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/303353/items/9CEKA4U3", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } } }, "data": { "key": "5IS36IMT", "version": 60, "parentItem": "9CEKA4U3", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-12-10T18:47:29Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/12413705", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-12-10T18:47:29Z", "dateModified": "2014-12-10T18:47:29Z" } }, { "key": "NDC2D8HM", "version": 60, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/NDC2D8HM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/NDC2D8HM", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } }, "creatorSummary": "Lino et al.", "parsedDate": "2004-01", "numChildren": 1 }, "data": { "key": "NDC2D8HM", "version": 60, "itemType": "journalArticle", "title": "Antidiabetic activity of Bauhinia forficata extracts in alloxan-diabetic rats", "creators": [ { "creatorType": "author", "firstName": "Cleide de Sousa", "lastName": "Lino" }, { "creatorType": "author", "firstName": "João Paulo Luz", "lastName": "Diógenes" }, { "creatorType": "author", "firstName": "Bruno Azevedo", "lastName": "Pereira" }, { "creatorType": "author", "firstName": "Rozilaine Aparecida Pelegrine Gomes", "lastName": "Faria" }, { "creatorType": "author", "firstName": "Manoel", "lastName": "Andrade Neto" }, { "creatorType": "author", "firstName": "Renata Sousa", "lastName": "Alves" }, { "creatorType": "author", "firstName": "Maria Goreti Rodrigues", "lastName": "de Queiroz" }, { "creatorType": "author", "firstName": "Francisca Cléa Florenço", "lastName": "de Sousa" }, { "creatorType": "author", "firstName": "Glauce Socorro Barros", "lastName": "Viana" } ], "abstractNote": "The antidiabetic activity of aqueous, ethanolic and hexanic extracts of Bauhinia forficata was investigated in a model of alloxan-induced diabetes in rats. The biochemical parameters studied were: plasma glucose, serum triglycerides, cholesterol, high density lipoprotein (HDL), and low density lipoprotein (LDL). Extracts were administered daily for 7 d at doses of 200 and 400 mg/kg, p.o., 48 h after alloxan injection (60 mg/kg, i.v.). The alloxan-diabetic rats showed significant reductions in plasma glucose, triglycerides, total cholesterol and HDL-cholesterol after treatment with the extracts and glibenclamide (used as standard) as compared to the diabetic controls. Levels of LDL were not altered. In conclusion, our results showed that the plant extracts when administered by gavage may reduce glucose, triglycerides, total cholesterol and HDL-cholesterol levels. These results suggest the validity of the clinical use of B. forficata in the treatment of diabetes mellitus type II.", "publicationTitle": "Biological & Pharmaceutical Bulletin", "publisher": "", "place": "", "date": "Jan 2004", "volume": "27", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "125-127", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Biol. Pharm. Bull.", "DOI": "", "citationKey": "", "url": "http://www.ncbi.nlm.nih.gov/pubmed/14709915", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0918-6158", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 14709915", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Bauhinia", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Cholesterol", "type": 1 }, { "tag": "Cholesterol, HDL", "type": 1 }, { "tag": "Diabetes Mellitus, Experimental", "type": 1 }, { "tag": "Ethanol", "type": 1 }, { "tag": "Glyburide", "type": 1 }, { "tag": "Hexanes", "type": 1 }, { "tag": "Hypoglycemic Agents", "type": 1 }, { "tag": "Lipids", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Phytotherapy", "type": 1 }, { "tag": "Plant Extracts", "type": 1 }, { "tag": "Plant Leaves", "type": 1 }, { "tag": "Rats", "type": 1 }, { "tag": "Rats, Wistar", "type": 1 }, { "tag": "Solvents", "type": 1 }, { "tag": "Triglycerides", "type": 1 }, { "tag": "Water", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-12-10T18:46:09Z", "dateModified": "2014-12-10T18:46:38Z" } }, { "key": "8MTA6XJW", "version": 60, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/8MTA6XJW", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/8MTA6XJW", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/303353/items/NDC2D8HM", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2171361, "username": "javieravaldes", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/javieravaldes", "type": "text/html" } } } }, "data": { "key": "8MTA6XJW", "version": 60, "parentItem": "NDC2D8HM", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-12-10T18:46:09Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/14709915", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-12-10T18:46:09Z", "dateModified": "2014-12-10T18:46:09Z" } }, { "key": "ZDKXXBR7", "version": 57, "library": { "type": "group", "id": 303353, "name": "Tesis bauhinia forficata", "links": { "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/303353/items/ZDKXXBR7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/tesis_bauhinia_forficata/items/ZDKXXBR7", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/303353/items/E4KGFUNX", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2166915, "username": "anto.latorre", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/anto.latorre", "type": "text/html" } } } }, "data": { "key": "ZDKXXBR7", "version": 57, "parentItem": "E4KGFUNX", "itemType": "attachment", "linkMode": "linked_url", "title": "Link to page at www.sciencedirect.com", "accessDate": "2014-12-10T18:45:30Z", "url": "http://www.sciencedirect.com/science/article/pii/S0944711309001676", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-12-10T18:45:30Z", "dateModified": "2014-12-10T18:45:30Z" } } ]