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            "title": "[Risk factors and screening for cardiac disease, carotid stenosis and aortic aneurysms in Sicily (Italy): a population-based cross sectional survey]",
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                    "firstName": "Sergio",
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            "publicationTitle": "Igiene E Sanità Pubblica",
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            "date": "2014 May-Jun",
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            "partNumber": "",
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            "pages": "267-282",
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            "shortTitle": "[Risk factors and screening for cardiac disease, carotid stenosis and aortic aneurysms in Sicily (Italy)",
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            "title": "Metabolic control and cardiovascular risk factors in type 2 diabetes mellitus patients according to diabetes duration",
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                    "firstName": "Josep",
                    "lastName": "Franch-Nadal"
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                    "creatorType": "author",
                    "firstName": "Antonio",
                    "lastName": "Rodriguez-Poncelas"
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                    "creatorType": "author",
                    "firstName": "Gabriel",
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                    "creatorType": "author",
                    "firstName": "Manel",
                    "lastName": "Mata-Cases"
                },
                {
                    "creatorType": "author",
                    "name": "on behalf of the GEDAPS (Primary care Group for the study of Diabetes)"
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            "abstractNote": "BACKGROUND: Control of glycaemic levels as well as cardiovascular risk factors (CVRF) is essential to prevent the onset of complications associated with type 2 diabetes mellitus (T2DM).\nAIM: To describe the degree of glycaemic control and CVRF in relation to diabetes duration.\nPATIENTS AND METHODS: Multicentre cross-sectional study in T2DM patients seen in primary care centres during 2007. Variables: Demographical and clinical characteristics, antidiabetic treatments and development of disease complications. Diabetes duration classification: 0-5, 6-10, 11-20 and >20 years. Logistic regression models were used in the analysis.\nRESULTS: A total of 3130 patients; 51.5% males; mean age: 68±11.7 years; mean diabetes duration:7.0 (±5.6) years, median: 5 (interquartile range:3-9) years; mean HbA1c: 6.84 (±1.5), were analyzed. There has been a progressive decline in HbA1c levels (HbA1c > 7% in 25.8% of patients during the first 5 years and 51.8% after 20 years). Blood pressure values remained relatively stable throughout disease duration. The mean value of low density lipoprotein (LDL) experienced a slight decline with the progression of the disease, but due to the significant increase of cardiovascular disease (CVD) after 20 years of duration, less patients reached the recommended target (LDL < 100mg/dl) in secondary prevention. Logistic regression model controlling for age, sex and CVD showed that diabetes duration was related to glycaemic control (odds ratio: 1.066, 95% confidence interval: 1.050-1.082 per year) but not to blood pressure or LDL control.\nCONCLUSIONS: The degree of glycaemic control and the risk factors in relation to the duration of T2DM followed different patterns. Diabetes duration was associated with a poorer glycaemic control but in general had a limited role in blood pressure control or lipid profile.",
            "publicationTitle": "Family Practice",
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            "date": "Sep 5, 2014",
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