[ { "key": "PU7QMPXZ", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/PU7QMPXZ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/PU7QMPXZ", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286420/items/FTPEDAZJ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } } }, "data": { "key": "PU7QMPXZ", "version": 2, "parentItem": "FTPEDAZJ", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-09T16:41:37Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25171842", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } }, { "key": "A67ZXZ5N", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/A67ZXZ5N", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/A67ZXZ5N", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286420/items/FTVZVVHT", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } } }, "data": { "key": "A67ZXZ5N", "version": 2, "parentItem": "FTVZVVHT", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-09T16:41:37Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25173426", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } }, { "key": "757ERX4S", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/757ERX4S", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/757ERX4S", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } }, "creatorSummary": "Rizwan et al.", "parsedDate": "2014-07", "numChildren": 1 }, "data": { "key": "757ERX4S", "version": 2, "itemType": "journalArticle", "title": "Temporal dimension in reference standard misclassification - a concept note", "creators": [ { "creatorType": "author", "firstName": "S. A.", "lastName": "Rizwan" }, { "creatorType": "author", "firstName": "Baridalyne", "lastName": "Nongkynrih" }, { "creatorType": "author", "firstName": "S. Lena", "lastName": "Charlette" }, { "creatorType": "author", "firstName": "Anand", "lastName": "Krishnan" } ], "abstractNote": "In situations of diagnostic tests studies where the gold standard (GS) test is not absolutely perfect, validity measures of index tests vary in subgroups with varying disease prevalence. This is called reference standard misclassification. Although this is widely known, little is explained about the variations in the performance of index tests when the validity of the GS test itself varies with the time duration of illness. This article attempts to expand the concept of reference standard misclassification specifically on the effect of time dependence of diagnostic tests. A brief literature review is also presented which documents the existent knowledge among researchers about the concept and the methods they usually employ to adjust. A list of solutions which can address the issue has also been discussed to enable researchers to design and analyse diagnostic test studies in better ways.", "publicationTitle": "Journal of clinical and diagnostic research: JCDR", "publisher": "", "place": "", "date": "Jul 2014", "volume": "8", "issue": "7", "section": "", "partNumber": "", "partTitle": "", "pages": "JE01-05", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J Clin Diagn Res", "DOI": "10.7860/JCDR/2014/8270.4571", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "2249-782X", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25177583 \nPMCID: PMC4149089", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } }, { "key": "8H5DAK4D", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/8H5DAK4D", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/8H5DAK4D", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286420/items/757ERX4S", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } } }, "data": { "key": "8H5DAK4D", "version": 2, "parentItem": "757ERX4S", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-09T16:41:37Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25177583", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } }, { "key": "FTPEDAZJ", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/FTPEDAZJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/FTPEDAZJ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } }, "creatorSummary": "Kothari et al.", "parsedDate": "2014-08-27", "numChildren": 1 }, "data": { "key": "FTPEDAZJ", "version": 2, "itemType": "journalArticle", "title": "Preparation and testing of a Vi conjugate vaccine using pneumococcal surface protein A (PspA) from Streptococcus pneumoniae as the carrier protein", "creators": [ { "creatorType": "author", "firstName": "Neha", "lastName": "Kothari" }, { "creatorType": "author", "firstName": "Kristopher R.", "lastName": "Genschmer" }, { "creatorType": "author", "firstName": "Sudeep", "lastName": "Kothari" }, { "creatorType": "author", "firstName": "Jeong Ah", "lastName": "Kim" }, { "creatorType": "author", "firstName": "David E.", "lastName": "Briles" }, { "creatorType": "author", "firstName": "Dong Kwon", "lastName": "Rhee" }, { "creatorType": "author", "firstName": "Rodney", "lastName": "Carbis" } ], "abstractNote": "In the current study pneumococcal surface protein A (PspA) was conjugated to Vi capsular polysaccharide from Salmonella Typhi to make available a vaccine against typhoid fever that has the potential to also provide broad protection from Streptococcus pneumoniae. High yielding production processes were developed for the purification of PspAs from families 1 and 2. The purified PspAs were conjugated to Vi with high recovery of both Vi and PspA. The processes developed especially for PspA family 2 could readily be adapted for large scale production under cGMP conditions. Previously we have shown that conjugation of diphtheria toxoid (DT) to Vi polysaccharide improves the immune response to Vi but can also enhance the response to DT. In this study it was shown that conjugation of PspA to Vi enhanced the anti-PspA response and that PspA was a suitable carrier protein as demonstrated by the characteristics of a T-cell dependent response to the Vi. We propose that a bivalent vaccine consisting of PspA from families 1 and 2 bound to Vi polysaccharide would protect against typhoid fever and has the potential to also protect against pneumococcal disease and should be considered for use in developing countries.", "publicationTitle": "Vaccine", "publisher": "", "place": "", "date": "Aug 27, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Vaccine", "DOI": "10.1016/j.vaccine.2014.08.041", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1873-2518", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25171842", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } }, { "key": "FTVZVVHT", "version": 2, "library": { "type": "group", "id": 286420, "name": "solotres", "links": { "alternate": { "href": "https://www.zotero.org/groups/solotres", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286420/items/FTVZVVHT", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/solotres/items/FTVZVVHT", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057661, "username": "casazola", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/casazola", "type": "text/html" } } }, "creatorSummary": "Dworkin et al.", "parsedDate": "2014-08-28", "numChildren": 1 }, "data": { "key": "FTVZVVHT", "version": 2, "itemType": "journalArticle", "title": "Burden of typhoid fever in Sulaimania, Iraqi Kurdistan", "creators": [ { "creatorType": "author", "firstName": "Jonathan", "lastName": "Dworkin" }, { "creatorType": "author", "firstName": "Rebeen", "lastName": "Saeed" }, { "creatorType": "author", "firstName": "Hawar", "lastName": "Mykhan" }, { "creatorType": "author", "firstName": "Shwan", "lastName": "Kanan" }, { "creatorType": "author", "firstName": "Dlawer", "lastName": "Farhad" }, { "creatorType": "author", "firstName": "Kocher Omer", "lastName": "Ali" }, { "creatorType": "author", "firstName": "Runak", "lastName": "Hawrami" }, { "creatorType": "author", "firstName": "John", "lastName": "Palardy" }, { "creatorType": "author", "firstName": "Marguerite A.", "lastName": "Neill" } ], "abstractNote": "BACKGROUND: Typhoid fever imposes a high disease burden worldwide, but resource limitations mean that the burden of typhoid fever in many countries is poorly understood.\nMETHODS: The authors conducted a prospective surveillance study at the adult and pediatric teaching hospitals in Sulaimania, Iraqi Kurdistan. All patients presenting with an undifferentiated febrile illness consistent with typhoid were eligible for enrollment. Enrolled patients had blood cultures and Brucella serologies performed. Incidence was calculated with reference to census data.\nRESULTS: Both typhoid fever and brucellosis were common, and the incidence of typhoid fever was 21 cases/100 000 patient-years. Classic disease symptoms were uncommonly observed.\nDISCUSSION: Cost-effective surveillance projects to calculate disease burden of typhoid fever are practical and replicable. Typhoid has successfully adapted to the healthcare environment in Sulaimania. Additional work in the region should focus on antibiotic resistance and other enteric pathogens such as Brucella spp.", "publicationTitle": "International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases", "publisher": "", "place": "", "date": "Aug 28, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Int. J. Infect. Dis.", "DOI": "10.1016/j.ijid.2014.07.005", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1878-3511", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25173426", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:41:37Z", "dateModified": "2014-09-09T16:41:37Z" } } ]