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"", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-16T17:42:04Z", "dateModified": "2014-09-16T17:42:04Z" } }, { "key": "VRDWEDST", "version": 4, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/VRDWEDST", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/VRDWEDST", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/martn_castilla", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "VRDWEDST", "version": 4, "itemType": "webpage", "title": "Infarto de miocardio tratamientos, síntomas e información en Dmedicina", "creators": [], "abstractNote": "", "websiteTitle": "", "websiteType": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.dmedicina.com/enfermedades/enfermedades-vasculares-y-del-corazon/infarto-miocardio", "accessDate": "2014-09-16T17:41:33Z", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-16T17:41:33Z", "dateModified": "2014-09-16T17:41:33Z" } }, { "key": "Q4ZI8WKP", "version": 3, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/Q4ZI8WKP", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/Q4ZI8WKP", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": 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"contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T16:16:56Z", "dateModified": "2014-09-09T16:16:56Z" } }, { "key": "8ZUTFW8K", "version": 2, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/8ZUTFW8K", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/8ZUTFW8K", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286407/items/2DCHVGKG", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/martn_castilla", "type": "text/html" } } } }, "data": { "key": "8ZUTFW8K", "version": 2, "parentItem": "2DCHVGKG", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-09T16:16:56Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25193735", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T16:16:56Z", "dateModified": "2014-09-09T16:16:56Z" } }, { "key": "ZRA5GP5B", "version": 2, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/ZRA5GP5B", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/ZRA5GP5B", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/martn_castilla", "type": "text/html" } } }, "creatorSummary": "Piccolo et al.", "parsedDate": "2014-07-30", "numChildren": 1 }, "data": { "key": "ZRA5GP5B", "version": 2, "itemType": "journalArticle", "title": "Effects of Baseline Coronary Occlusion and Diabetes Mellitus in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention", "creators": [ { "creatorType": "author", "firstName": "Raffaele", "lastName": "Piccolo" }, { "creatorType": "author", "firstName": "Gennaro", "lastName": "Galasso" }, { "creatorType": "author", "firstName": "Allan Zeeberg", "lastName": "Iversen" }, { "creatorType": "author", "firstName": "Ingo", "lastName": "Eitel" }, { "creatorType": "author", "firstName": "Alberto", "lastName": "Dominguez-Rodriguez" }, { "creatorType": "author", "firstName": "Youlan L.", "lastName": "Gu" }, { "creatorType": "author", "firstName": "Bart J. G. L.", "lastName": "de Smet" }, { "creatorType": "author", "firstName": "Karim D.", "lastName": "Mahmoud" }, { "creatorType": "author", "firstName": "Pedro", "lastName": "Abreu-Gonzalez" }, { "creatorType": "author", "firstName": "Bruno", "lastName": "Trimarco" }, { "creatorType": "author", "firstName": "Holger", "lastName": "Thiele" }, { "creatorType": "author", "firstName": "Federico", "lastName": "Piscione" } ], "abstractNote": "Several studies have highlighted the prognostic role of preprocedural Thrombolysis In Myocardial Infarction (TIMI) flow in the infarct-related artery (IRA) in patients with ST-segment elevation myocardial infarction (STEMI). However, the impact of preprocedural IRA occlusion in patients with diabetes with STEMI has been insufficiently studied. The aim of this study was to evaluate the effects of baseline IRA occlusion and diabetic status in patients with STEMI who underwent primary percutaneous coronary intervention by using data from a pooled analysis of randomized trials comparing intracoronary with intravenous abciximab bolus administration. A total of 3,046 patients with STEMI who underwent primary percutaneous coronary intervention were included. Diabetes was present in 578 patients (19%). The primary outcome was mortality after a median follow-up period of 375 days. Secondary end points were reinfarction and stent thrombosis. In patients without diabetes, IRA occlusion versus no occlusion was not associated with increased rates of mortality (4.3% vs 2.7%, p = 0.051) and reinfarction (3.3% vs 2.5%, p = 0.33). Patients with diabetes with IRA occlusion compared with those without occlusion showed higher rates of mortality (10.6% vs 4.6%, p = 0.01) and reinfarction (5.6% vs 2.1%, p = 0.03). Baseline IRA occlusion increased the rate of stent thrombosis in the nondiabetic (2.1% vs 1.0%, p = 0.04) and diabetic (3.2% vs 0.8%, p = 0.05) cohorts. Interaction analysis demonstrated that the risk for death and reinfarction was significantly increased when diabetes and IRA occlusion occurred concomitantly. In conclusion, patients with STEMI with diabetes and baseline IRA occlusion had disproportionately higher rates of death and reinfarction. Preprocedural IRA occlusion increased the risk for stent thrombosis, irrespective of diabetic status.", "publicationTitle": "The American Journal of Cardiology", "publisher": "", "place": "", "date": "Jul 30, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Am. J. Cardiol.", "DOI": "10.1016/j.amjcard.2014.07.030", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1879-1913", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25193670", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:16:56Z", "dateModified": "2014-09-09T16:16:56Z" } }, { "key": "2DCHVGKG", "version": 2, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/2DCHVGKG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/2DCHVGKG", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/martn_castilla", "type": "text/html" } } }, "creatorSummary": "Liu et al.", "parsedDate": "2014-09-05", "numChildren": 1 }, "data": { "key": "2DCHVGKG", "version": 2, "itemType": "journalArticle", "title": "Statins for the Prevention of Contrast-Induced Nephropathy After Coronary Angiography/Percutaneous Interventions: A Meta-analysis of Randomized Controlled Trials", "creators": [ { "creatorType": "author", "firstName": "Yuan-Hui", "lastName": "Liu" }, { "creatorType": "author", "firstName": "Yong", "lastName": "Liu" }, { "creatorType": "author", "firstName": "Chong-Yang", "lastName": "Duan" }, { "creatorType": "author", "firstName": "Ning", "lastName": "Tan" }, { "creatorType": "author", "firstName": "Ji-Yan", "lastName": "Chen" }, { "creatorType": "author", "firstName": "Ying-Ling", "lastName": "Zhou" }, { "creatorType": "author", "firstName": "Li-Wen", "lastName": "Li" }, { "creatorType": "author", "firstName": "Peng-Cheng", "lastName": "He" } ], "abstractNote": "BACKGROUND: Statins have been demonstrated to prevent the development of contrast-induced nephropathy (CIN). Nevertheless, clinical research has indicated conflicting results. We performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the protective effects of statins on CIN and the requirement of renal replacement therapy (RRT) in patients undergoing coronary angiography/percutaneous interventions.\nMETHODS: PubMed, MEDLINE, Web of Science, EMBASE, ClinicalTrials.gov, and the Cochrane Central RCTs were searched for RCTs from inception to February 2014 to compare statins with placebo treatment for preventing CIN in patients undergoing coronary angiography/percutaneous interventions.\nRESULTS: Nine RCTs were identified and analyzed in a total of 5143 patients involving 2560 patients with statin pretreatment and 2583 patients as control. Patients who received statin therapy had a 53% lower risk of CIN with different definitions (within 48 or 72 hours) compared to the control group based on a fixed effect model (risk ratio = 0.47, 95% confidence interval = 0.37-0.60, P < .0001) and were less likely to require RRT based on Peto fixed effect. Subgroup analysis showed that statin pretreatment could decrease the incidence of CIN in patients with preexisting renal dysfunction or diabetes mellitus. In addition, patients on rosuvastatin had a similar reduced incidence of CIN compared to patients on atorvastatin.\nCONCLUSION: This updated meta-analysis demonstrated that preprocedural statin treatment could reduce the risk of CIN and the need for RRT in patients undergoing coronary angiography/percutaneous interventions. Moreover, statin therapy would be helpful in reducing the incidence of CIN in high-risk patients with preexisting renal dysfunction or diabetes mellitus. Additionally, rosuvastatin and atorvastatin had similar efficacies in preventing CIN development.", "publicationTitle": "Journal of Cardiovascular Pharmacology and Therapeutics", "publisher": "", "place": "", "date": "Sep 5, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "J. Cardiovasc. Pharmacol. Ther.", "DOI": "10.1177/1074248414549462", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1940-4034", "archive": "", "archiveLocation": "", "shortTitle": "Statins for the Prevention of Contrast-Induced Nephropathy After Coronary Angiography/Percutaneous Interventions", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25193735", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:16:56Z", "dateModified": "2014-09-09T16:16:56Z" } }, { "key": "KI75JB3V", "version": 2, "library": { "type": "group", "id": 286407, "name": "medusmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medusmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286407/items/KI75JB3V", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medusmp/items/KI75JB3V", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057699, "username": "Martín Castilla", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/martn_castilla", "type": "text/html" } } }, "creatorSummary": "Stolic et al.", "parsedDate": "2014-10", "numChildren": 1 }, "data": { "key": "KI75JB3V", "version": 2, "itemType": "journalArticle", "title": "Predictive parameters of survival in hemodialysis patients with restless leg syndrome", "creators": [ { "creatorType": "author", "firstName": "Radojica V.", "lastName": "Stolic" }, { "creatorType": "author", "firstName": "Goran Z.", "lastName": "Trajkovic" }, { "creatorType": "author", "firstName": "Djole", "lastName": "Jekic" }, { "creatorType": "author", "firstName": "Sasa R.", "lastName": "Sovtic" }, { "creatorType": "author", "firstName": "Aleksandar N.", "lastName": "Jovanovic" }, { "creatorType": "author", "firstName": "Dragica Z.", "lastName": "Stolic" }, { "creatorType": "author", "firstName": "Marijana S.", "lastName": "Stanojevic-Pirkovic" }, { "creatorType": "author", "firstName": "Zorana", "lastName": "Djordjevic" } ], "abstractNote": "Restless leg syndrome (RLS) affects the quality of life and survival in patients on hemodialysis (HD). The aim of this study was to determine the characteristics and survival parameters in patients on HD with RLS. This study was a non-randomized clinical study involving 204 patients on HD, of whom 71 were female and 133 were male. Symptoms of RLS were defined as positive responses to four questions comprising the criteria of RLS. We recorded the outcome of treatment, biochemical analyses, demographic, sexual, anthropometric and clinical characteristics in all study patients. Patients with RLS who completed the study had a significantly higher body mass index and lower intima-media thickness and flow through the arteriovenous fistula. Among patients with RLS who died, there were more smokers as well as higher incidences of cardiovascular disease and diabetes mellitus. Among patients with RLS who survived, there were a greater number of patients with preserved diuresis and receiving erythropoietin therapy. Patients who completed the study had significantly higher levels of hemoglobin, creatinine, serum iron and transferrin satura-tion. Diabetes mellitus (B = 1.802; P = 0.002) and low Kt/V (B = -5.218; P = 0.001) were major predictive parameters for survival.", "publicationTitle": "Saudi Journal of Kidney Diseases and Transplantation: An Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia", "publisher": "", "place": "", "date": "2014 Sep-Oct", "volume": "25", "issue": "5", "section": "", "partNumber": "", "partTitle": "", "pages": "974-980", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Saudi J Kidney Dis Transpl", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1319-2442", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25193893", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-09T16:16:56Z", "dateModified": "2014-09-09T16:16:56Z" } } ]