[ { "key": "598MA8K3", "version": 7, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/598MA8K3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/598MA8K3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "598MA8K3", "version": 7, "itemType": "webpage", "title": "Infarto do Miocárdio - Hospital Israelita Albert Einstein", "creators": [], "abstractNote": "Hospital Israelita Albert Einstein, São Paulo, Brasil. Muito mais que um hospital. Excelência em saúde, ensino, pesquisa e responsabilidade social.", "websiteTitle": "", "websiteType": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.einstein.br/einstein-saude/primeiros-socorros/Paginas/infarto-do-miocardio.aspx", "accessDate": "2014-09-16T14:22:15Z", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-16T14:48:43Z", "dateModified": "2014-09-16T14:48:43Z" } }, { "key": "G6UK8EDQ", "version": 7, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/G6UK8EDQ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/G6UK8EDQ", "type": "text/html" } }, "meta": { 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"links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/BEX3MTNM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/BEX3MTNM", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "BEX3MTNM", "version": 7, "itemType": "webpage", "title": "Aneurisma cerebral", "creators": [], "abstractNote": "", "websiteTitle": "University of Maryland Medical Center", "websiteType": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://umms.org/shore-health/health/medical/spanishency/animations/aneurisma-cerebral", "accessDate": "", "shortTitle": "", "language": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-16T14:48:39Z", "dateModified": "2014-09-16T14:48:39Z" } }, { "key": "D2P3U6DK", "version": 7, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/D2P3U6DK", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/D2P3U6DK", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "creatorSummary": "Dr. Nelson V.", "numChildren": 0 }, "data": { "key": "D2P3U6DK", "version": 7, "itemType": "webpage", "title": "Aneurisma cerebral", "creators": [ { "creatorType": "author", "firstName": "Dr. Marcelo F.", "lastName": "Dr. Nelson V." } ], "abstractNote": "", "websiteTitle": "ABC de Saúde", "websiteType": "", "date": "", "publisher": "", "place": "", "DOI": "", "citationKey": "", "url": "http://www.abcdasaude.com.br/neurologia/aneurisma-cerebral", "accessDate": "", "shortTitle": "", "language": "portugues", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-16T14:48:37Z", "dateModified": "2014-09-16T14:48:37Z" } }, { "key": "C8MXKHC9", "version": 2, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/C8MXKHC9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/C8MXKHC9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "creatorSummary": "Yadla et al.", "parsedDate": "2014-03", "numChildren": 1 }, "data": { "key": "C8MXKHC9", "version": 2, "itemType": "journalArticle", "title": "A clinical study of bilateral non-obstructive acute pyelonephritis with acute kidney injury in patients of type 2 diabetes mellitus", "creators": [ { "creatorType": "author", "firstName": "Manjusha", "lastName": "Yadla" }, { "creatorType": "author", "firstName": "Sriramnaveen", "lastName": "Parvithina" }, { "creatorType": "author", "firstName": "Krishna Kishore", "lastName": "Chennu" }, { "creatorType": "author", "firstName": "Sandeep", "lastName": "Reddy" }, { "creatorType": "author", "firstName": "A. V. S. S. N.", "lastName": "Sridhar" }, { "creatorType": "author", "firstName": "B.", "lastName": "Vijayalakshmi" }, { "creatorType": "author", "firstName": "A. Y.", "lastName": "Lakshmi" }, { "creatorType": "author", "firstName": "Tek Chand", "lastName": "Kalawat" }, { "creatorType": "author", "firstName": "V.", "lastName": "Sivakumar" } ], "abstractNote": "The aim of our study was to study the clinical profile of type 2 diabetes mellitus patients admitted with the diagnosis of acute kidney injury (AKI) due to bilateral acute non-obstructive pyelonephritis. The bilateral involvement was identified on various imaging modalities (ultrasound, computed tomography, nuclear scintigrapy). All the patients had AKI. Those with severe AKI underwent hemodialysis. The factors associated with the severity of illness were identified. Twenty-five patients of type 2 diabetes mellitus admitted with the diagnosis of AKI due to bilateral acute non-obstructive pyelonephritis were identified. On ultrasound, bilateral involvement was found in 12 patients and in 17 patients on computed tomography and eight patients on nuclear scintigraphy. Fourteen of them needed dialysis support. Bilateral acute pyelonephritis needs to be considered while evaluating the AKI in type 2 diabetes mellitus patients.", "publicationTitle": "Saudi Journal of Kidney Diseases and Transplantation: An Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia", "publisher": "", "place": "", "date": "Mar 2014", "volume": "25", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "338-342", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Saudi J Kidney Dis Transpl", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1319-2442", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 24626001", "tags": [ { "tag": "Acute Disease", "type": 1 }, { "tag": "Acute Kidney Injury", "type": 1 }, { "tag": "Aged", "type": 1 }, { "tag": "Diabetic Nephropathies", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Pyelonephritis", "type": 1 }, { "tag": "Renal Dialysis", "type": 1 }, { "tag": "Retrospective Studies", "type": 1 }, { "tag": "Tomography, X-Ray Computed", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-09T14:31:31Z", "dateModified": "2014-09-09T14:31:31Z" } }, { "key": "DFV8U64F", "version": 2, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/DFV8U64F", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/DFV8U64F", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286342/items/C8MXKHC9", "type": "application/json" } }, "meta": { 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"text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/PXBUIHZA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/PXBUIHZA", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286342/items/3KUK6FF9", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } } }, "data": { "key": "PXBUIHZA", "version": 2, "parentItem": "3KUK6FF9", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-09T14:31:31Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/24920915", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-09T14:31:31Z", "dateModified": "2014-09-09T14:31:31Z" } }, { "key": "QCV9GT9X", "version": 2, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/QCV9GT9X", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/QCV9GT9X", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "creatorSummary": "Yu et al.", "parsedDate": "2014", "numChildren": 1 }, "data": { "key": "QCV9GT9X", "version": 2, "itemType": "journalArticle", "title": "The impact of soluble dietary fibre on gastric emptying, postprandial blood glucose and insulin in patients with type 2 diabetes", "creators": [ { "creatorType": "author", "firstName": "Kang", "lastName": "Yu" }, { "creatorType": "author", "firstName": "Mei-Yun", "lastName": "Ke" }, { "creatorType": "author", "firstName": "Wen-Hui", "lastName": "Li" }, { "creatorType": "author", "firstName": "Shu-Qin", "lastName": "Zhang" }, { "creatorType": "author", "firstName": "Xiu-Cai", "lastName": "Fang" } ], "abstractNote": "Dietary fibre plays an important role in controlling postprandial glycemic and insulin response in diabetic patients. The intake of dietary fibre has been shown to delay the gastric emptying in healthy subjects. The relationship between gastric emptying and postprandial blood glucose in diabetic patients with fibre-load liquids needs to be investigated. To investigate the impact of soluble dietary fibre (SDF) on gastric emptying, postprandial glycemic and insulin response in patients with type 2 diabetes. 30 patients with type 2 diabetes (DM) and 10 healthy subjects (HS) matched for gender and age were randomized to receive SDF-free liquid (500 mL, 500 Kcal) and isoenergetic SDF liquid (oat β-glucan 7.5 g, 500 mL, 500 Kcal) on two separate days based on a cross-over with 6-day wash-out period. Gastric emptying was monitored by ultrasonography at intervals of 30 min for 2 hours. Fasting and postprandial blood was collected at intervals of 30-60 min for 180 min to determine plasma glucose and insulin. Proximal gastric emptying was delayed by SDF-treatment both in DM (p=0.001) and HS (p=0.037). SDF resulted in less output volume in the distal stomach in DM (p<0.05). SDF decreased postprandial glucose (p=0.001) and insulin (p=0.001) in DM subjects. Postprandial glucose (r=-0.547, p=0.047) and insulin (r=-0.566, p=0.004) were negatively correlated with distal emptying of SDF in DM subjects. Distal gastric emptying was delayed significantly in DM subjects with HbA1c levels ≥6.5% (p=0.021) or with complications (p=0.011) by SDF, respectively. SDF improved postprandial glycaemia which was related to slowing of gastric emptying.", "publicationTitle": "Asia Pacific Journal of Clinical Nutrition", "publisher": "", "place": "", "date": "2014", "volume": "23", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "210-218", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Asia Pac J Clin Nutr", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0964-7058", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 24901089", "tags": [ { "tag": "Aged", "type": 1 }, { "tag": "Beverages", "type": 1 }, { "tag": "Biological Markers", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Cross-Over Studies", "type": 1 }, { "tag": "Diabetes Mellitus, Type 2", "type": 1 }, { "tag": "Dietary Fiber", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Gastric Emptying", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Insulin", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Postprandial Period", "type": 1 }, { "tag": "Prospective Studies", "type": 1 }, { "tag": "Stomach", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-09T14:31:31Z", "dateModified": "2014-09-09T14:31:31Z" } }, { "key": "3KUK6FF9", "version": 2, "library": { "type": "group", "id": 286342, "name": "Informatica Medica 24S XD", "links": { "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286342/items/3KUK6FF9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/informatica_medica_24s_xd/items/3KUK6FF9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2057443, "username": "samuel130", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/samuel130", "type": "text/html" } } }, "creatorSummary": "Hassanein et al.", "parsedDate": "2014", "numChildren": 1 }, "data": { "key": "3KUK6FF9", "version": 2, "itemType": "journalArticle", "title": "A double-blind, randomized trial, including frequent patient-physician contacts and Ramadan-focused advice, assessing vildagliptin and gliclazide in patients with type 2 diabetes fasting during Ramadan: the STEADFAST study", "creators": [ { "creatorType": "author", "firstName": "Mohamed", "lastName": "Hassanein" }, { "creatorType": "author", "firstName": "Khalifa", "lastName": "Abdallah" }, { "creatorType": "author", "firstName": "Anja", "lastName": "Schweizer" } ], "abstractNote": "BACKGROUND: Several observational studies were conducted with vildagliptin in patients with type 2 diabetes mellitus (T2DM) fasting during Ramadan, showing significantly lower incidences of hypoglycemia with vildagliptin versus sulfonylureas, including gliclazide. It was of interest to complement the existing real-life evidence with data from a randomized, double-blind, clinical trial.\nCLINICAL TRIALS IDENTIFIER: NCT01758380.\nMETHODS: This multiregional, double-blind study randomized 557 patients with T2DM (mean glycated hemoglobin [HbA1c], 6.9%), previously treated with metformin and any sulfonylurea to receive either vildagliptin (50 mg twice daily) or gliclazide plus metformin. The study included four office visits (three pre-Ramadan) and multiple telephone contacts, as well as Ramadan-focused advice. Hypoglycemic events were assessed during Ramadan; HbA(1c) and weight were analyzed before and after Ramadan.\nRESULTS: The proportion of patients reporting confirmed (<3.9 mmol/L and/or severe) hypoglycemic events during Ramadan was 3.0% with vildagliptin and 7.0% with gliclazide (P=0.039; one-sided test), and this was 6.0% and 8.7%, respectively, for any hypoglycemic events (P=0.173). The adjusted mean change pre- to post-Ramadan in HbA(1c) was 0.05%±0.04% with vildagliptin and -0.03%±0.04% with gliclazide, from baselines of 6.84% and 6.79%, respectively (P=0.165). In both groups, the adjusted mean decrease in weight was -1.1±0.2 kg (P=0.987). Overall safety was similar between the treatments.\nCONCLUSION: In line with the results from previous observational studies, vildagliptin was shown in this interventional study to be an effective, safe, and well-tolerated treatment in patients with T2DM fasting during Ramadan, with a consistently low incidence of hypoglycemia across studies, accompanied by good glycemic and weight control. In contrast, gliclazide showed a lower incidence of hypoglycemia in the present interventional than the previous observational studies. This is suggested to be linked to the specific circumstances of this study, including frequent patient-physician contacts, Ramadan-focused advice, a recent switch in treatment, and very well-controlled patients, which is different from what is often seen in real life.", "publicationTitle": "Vascular Health and Risk Management", "publisher": "", "place": "", "date": "2014", "volume": "10", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "319-326", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Vasc Health Risk Manag", "DOI": "10.2147/VHRM.S64038", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1178-2048", "archive": "", "archiveLocation": "", "shortTitle": "A double-blind, randomized trial, including frequent patient-physician contacts and Ramadan-focused advice, assessing vildagliptin and gliclazide in patients with type 2 diabetes fasting during Ramadan", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 24920915 \nPMCID: PMC4045264", "tags": [ { "tag": "Adamantane", "type": 1 }, { "tag": "Asia", "type": 1 }, { "tag": "Biological Markers", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "Body Weight", "type": 1 }, { "tag": "Counseling", "type": 1 }, { "tag": "Diabetes Mellitus, Type 2", "type": 1 }, { "tag": "Dipeptidyl-Peptidase IV Inhibitors", "type": 1 }, { "tag": "Double-Blind Method", "type": 1 }, { "tag": "Europe", "type": 1 }, { "tag": "Fasting", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Gliclazide", "type": 1 }, { "tag": "Hemoglobin A, Glycosylated", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Hypoglycemia", "type": 1 }, { "tag": "Hypoglycemic Agents", "type": 1 }, { "tag": "Islam", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Medication Adherence", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Middle East", "type": 1 }, { "tag": "Nitriles", "type": 1 }, { "tag": "Office Visits", "type": 1 }, { "tag": "Pyrrolidines", "type": 1 }, { "tag": "Religion and Medicine", "type": 1 }, { "tag": "Telephone", "type": 1 }, { "tag": "Time Factors", "type": 1 }, { "tag": "Treatment Outcome", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-09T14:31:31Z", "dateModified": "2014-09-09T14:31:31Z" } } ]