[ { "key": "8ET73DQM", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/8ET73DQM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/8ET73DQM", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286007/items/2GD6JMGC", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } } }, "data": { "key": "8ET73DQM", "version": 2, "parentItem": "2GD6JMGC", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T20:57:33Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25073208", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } }, { "key": "2GD6JMGC", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/2GD6JMGC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/2GD6JMGC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } }, "creatorSummary": "Collin et al.", "parsedDate": "2014-04", "numChildren": 1 }, "data": { "key": "2GD6JMGC", "version": 2, "itemType": "journalArticle", "title": "Solid pseudopapillary tumor of the pancreas: a report of six cases", "creators": [ { "creatorType": "author", "firstName": "M.", "lastName": "Collin" }, { "creatorType": "author", "firstName": "P.", "lastName": "Honoré" }, { "creatorType": "author", "firstName": "A.", "lastName": "De Roover" }, { "creatorType": "author", "firstName": "M.", "lastName": "Meurisse" } ], "abstractNote": "BACKGROUND: Solid pseudopapillary tumor of the pancreas (SPTP) is a rare pancreatic neoplasm. The aim of this study was to discuss the clinical presentation, management, and outcome of patients with this kind of tumor.\nMATERIALS AND METHODS: A retrospective review was performed in 6 patients with SPTP surgically treated between January 2004 and September 2011 in our hospital.\nRESULTS: All the 6 patients were female. The mean age of the patients was 39 years (range, 18 to 67 years). The main clinical presentation was abdominal pain or discomfort, however a third of the patients were asymptomatic. The mean size of the tumor was 9.7 cm (range, 2.5 to 18 cm). Three tumors had a well defined capsule, 3 tumors extended in the pancreas. Four of the 6 tumors had a cystic component, and calcifications were observed in one tumor. No lymph node involvement, no lymphatic invasion and no nerve invasion were observed. One tumor showed an infiltration of the splenic vein, and another patient had a liver metastasis with complete resection. Distal pancreatectomy (n = 3), local resection (n = 1), cephalic duodenopancreatectomy (n = 1), and distal pancreatectomy associated with a right hepatectomy (n = 1) were performed. The main postoperative complication in the short-term was bleeding (n = 1), and long-term the development of an insulin-requiring diabetes (n = 2). No patient received adjuvant therapy. Overall mortality rate was 0%. All patients were still alive without recurrent disease with a median follow up of 36.2 months.\nCONCLUSION: Patients with SPTP have an excellent prognosis after its complete removal, even if it is a minimized resection.", "publicationTitle": "Acta Chirurgica Belgica", "publisher": "", "place": "", "date": "2014 Mar-Apr", "volume": "114", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "110-114", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Acta Chir. Belg.", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0001-5458", "archive": "", "archiveLocation": "", "shortTitle": "Solid pseudopapillary tumor of the pancreas", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25073208", "tags": [ { "tag": "Abdominal Pain", "type": 1 }, { "tag": "Adolescent", "type": 1 }, { "tag": "Adult", "type": 1 }, { "tag": "Aged", "type": 1 }, { "tag": "Carcinoma, Papillary", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Pancreatectomy", "type": 1 }, { "tag": "Pancreatic Neoplasms", "type": 1 }, { "tag": "Pancreaticoduodenectomy", "type": 1 }, { "tag": "Prognosis", "type": 1 }, { "tag": "Retrospective Studies", "type": 1 }, { "tag": "Young Adult", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } }, { "key": "W827TFDN", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/W827TFDN", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/W827TFDN", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286007/items/XNU7E6R9", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } } }, "data": { "key": "W827TFDN", "version": 2, "parentItem": "XNU7E6R9", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T20:57:37Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25073240", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } }, { "key": "275FWZUM", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/275FWZUM", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/275FWZUM", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/286007/items/RSRM5QPP", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } } }, "data": { "key": "275FWZUM", "version": 2, "parentItem": "RSRM5QPP", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T20:57:24Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25014687", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } }, { "key": "XNU7E6R9", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/XNU7E6R9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/XNU7E6R9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } }, "creatorSummary": "Macin et al.", "parsedDate": "2014-04", "numChildren": 1 }, "data": { "key": "XNU7E6R9", "version": 2, "itemType": "journalArticle", "title": "Pancreatic cystic lymphangioma: diagnostic approach with MDCT and MR imaging", "creators": [ { "creatorType": "author", "firstName": "G.", "lastName": "Macin" }, { "creatorType": "author", "firstName": "K.", "lastName": "Hekimoglu" }, { "creatorType": "author", "firstName": "H.", "lastName": "Uner" }, { "creatorType": "author", "firstName": "C.", "lastName": "Tarhan" } ], "abstractNote": "Lymphangiomas are rare congenital benign tumors arising from the lymphatic system mostly encountered in the neck and axillary regions of pediatric patients. Pancreatic cystic lymphangiomas very rarely occur in adults. Radiologically, the lesion may mimic pancreatic carcinoma and should be considered in the differential diagnosis of any patient found to have an abdominal cystic mass. In this article, we present a 50-year-old man who presented with pain in the upper abdomen, nausea, and abdominal swelling. On computed tomography (CT) and magnetic resonance (MR) imaging, a gross septated cystic lesion was detected in the upper abdomen which extended from the pancreatic corpus to the left liver lobe. The patient underwent complete resection of tumor. Pathology revealed a cystic lymphangioma.", "publicationTitle": "JBR-BTR: organe de la Société royale belge de radiologie (SRBR) = orgaan van de Koninklijke Belgische Vereniging voor Radiologie (KBVR)", "publisher": "", "place": "", "date": "2014 Mar-Apr", "volume": "97", "issue": "2", "section": "", "partNumber": "", "partTitle": "", "pages": "97-99", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "JBR-BTR", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0302-7430", "archive": "", "archiveLocation": "", "shortTitle": "Pancreatic cystic lymphangioma", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25073240", "tags": [ { "tag": "Contrast Media", "type": 1 }, { "tag": "Diagnosis, Differential", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Lymphangioma, Cystic", "type": 1 }, { "tag": "Magnetic Resonance Imaging", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Multidetector Computed Tomography", "type": 1 }, { "tag": "Pancreas", "type": 1 }, { "tag": "Pancreatic Neoplasms", "type": 1 }, { "tag": "Radiographic Image Enhancement", "type": 1 }, { "tag": "Treatment Outcome", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } }, { "key": "RSRM5QPP", "version": 2, "library": { "type": "group", "id": 286007, "name": "medicinausmp", "links": { "alternate": { "href": "https://www.zotero.org/groups/medicinausmp", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/286007/items/RSRM5QPP", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/medicinausmp/items/RSRM5QPP", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055915, "username": "Sharline Oviedo Soto", "name": "sharline", "links": { "alternate": { "href": "https://www.zotero.org/sharline_oviedo_soto", "type": "text/html" } } }, "creatorSummary": "Caplin et al.", "parsedDate": "2014-07-17", "numChildren": 1 }, "data": { "key": "RSRM5QPP", "version": 2, "itemType": "journalArticle", "title": "Lanreotide in metastatic enteropancreatic neuroendocrine tumors", "creators": [ { "creatorType": "author", "firstName": "Martyn E.", "lastName": "Caplin" }, { "creatorType": "author", "firstName": "Marianne", "lastName": "Pavel" }, { "creatorType": "author", "firstName": "Jarosław B.", "lastName": "Ćwikła" }, { "creatorType": "author", "firstName": "Alexandria T.", "lastName": "Phan" }, { "creatorType": "author", "firstName": "Markus", "lastName": "Raderer" }, { "creatorType": "author", "firstName": "Eva", "lastName": "Sedláčková" }, { "creatorType": "author", "firstName": "Guillaume", "lastName": "Cadiot" }, { "creatorType": "author", "firstName": "Edward M.", "lastName": "Wolin" }, { "creatorType": "author", "firstName": "Jaume", "lastName": "Capdevila" }, { "creatorType": "author", "firstName": "Lucy", "lastName": "Wall" }, { "creatorType": "author", "firstName": "Guido", "lastName": "Rindi" }, { "creatorType": "author", "firstName": "Alison", "lastName": "Langley" }, { "creatorType": "author", "firstName": "Séverine", "lastName": "Martinez" }, { "creatorType": "author", "firstName": "Joëlle", "lastName": "Blumberg" }, { "creatorType": "author", "firstName": "Philippe", "lastName": "Ruszniewski" }, { "creatorType": "author", "name": "CLARINET Investigators" } ], "abstractNote": "BACKGROUND: Somatostatin analogues are commonly used to treat symptoms associated with hormone hypersecretion in neuroendocrine tumors; however, data on their antitumor effects are limited.\nMETHODS: We conducted a randomized, double-blind, placebo-controlled, multinational study of the somatostatin analogue lanreotide in patients with advanced, well-differentiated or moderately differentiated, nonfunctioning, somatostatin receptor-positive neuroendocrine tumors of grade 1 or 2 (a tumor proliferation index [on staining for the Ki-67 antigen] of <10%) and documented disease-progression status. The tumors originated in the pancreas, midgut, or hindgut or were of unknown origin. Patients were randomly assigned to receive an extended-release aqueous-gel formulation of lanreotide (Autogel [known in the United States as Depot], Ipsen) at a dose of 120 mg (101 patients) or placebo (103 patients) once every 28 days for 96 weeks. The primary end point was progression-free survival, defined as the time to disease progression (according to the Response Evaluation Criteria in Solid Tumors, version 1.0) or death. Secondary end points included overall survival, quality of life (assessed with the European Organization for Research and Treatment of Cancer questionnaires QLQ-C30 and QLQ-GI.NET21), and safety.\nRESULTS: Most patients (96%) had no tumor progression in the 3 to 6 months before randomization, and 33% had hepatic tumor volumes greater than 25%. Lanreotide, as compared with placebo, was associated with significantly prolonged progression-free survival (median not reached vs. median of 18.0 months, P<0.001 by the stratified log-rank test; hazard ratio for progression or death, 0.47; 95% confidence interval [CI], 0.30 to 0.73). The estimated rates of progression-free survival at 24 months were 65.1% (95% CI, 54.0 to 74.1) in the lanreotide group and 33.0% (95% CI, 23.0 to 43.3) in the placebo group. The therapeutic effect in predefined subgroups was generally consistent with that in the overall population, with the exception of small subgroups in which confidence intervals were wide. There were no significant between-group differences in quality of life or overall survival. The most common treatment-related adverse event was diarrhea (in 26% of the patients in the lanreotide group and 9% of those in the placebo group).\nCONCLUSIONS: Lanreotide was associated with significantly prolonged progression-free survival among patients with metastatic enteropancreatic neuroendocrine tumors of grade 1 or 2 (Ki-67 <10%). (Funded by Ipsen; CLARINET ClinicalTrials.gov number, NCT00353496; EudraCT 2005-004904-35.).", "publicationTitle": "The New England Journal of Medicine", "publisher": "", "place": "", "date": "Jul 17, 2014", "volume": "371", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "224-233", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "N. Engl. J. Med.", "DOI": "10.1056/NEJMoa1316158", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1533-4406", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25014687", "tags": [ { "tag": "Aged", "type": 1 }, { "tag": "Antineoplastic Agents", "type": 1 }, { "tag": "Delayed-Action Preparations", "type": 1 }, { "tag": "Diarrhea", "type": 1 }, { "tag": "Disease-Free Survival", "type": 1 }, { "tag": "Double-Blind Method", "type": 1 }, { "tag": "Female", "type": 1 }, { "tag": "Gastrointestinal Neoplasms", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Neuroendocrine Tumors", "type": 1 }, { "tag": "Pancreatic Neoplasms", "type": 1 }, { "tag": "Peptides, Cyclic", "type": 1 }, { "tag": "Somatostatin", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:25:16Z", "dateModified": "2014-09-08T21:25:16Z" } } ]