[ { "key": "ZF9F9268", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/ZF9F9268", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/ZF9F9268", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/285989/items/PISE5N8Z", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } } }, "data": { "key": "ZF9F9268", "version": 2, "parentItem": "PISE5N8Z", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T21:19:33Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25193741", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } }, { "key": "DJ7TXWFK", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/DJ7TXWFK", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/DJ7TXWFK", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/285989/items/37FDATIR", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } } }, "data": { "key": "DJ7TXWFK", "version": 2, "parentItem": "37FDATIR", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T21:19:33Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25194153", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } }, { "key": "37FDATIR", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/37FDATIR", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/37FDATIR", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } }, "creatorSummary": "Qiao et al.", "parsedDate": "2014-09-06", "numChildren": 1 }, "data": { "key": "37FDATIR", "version": 2, "itemType": "journalArticle", "title": "Expression of Collapsin Response Mediator Protein 1 in Placenta of Normal Gestation and Link to Early-Onset Preeclampsia", "creators": [ { "creatorType": "author", "firstName": "Chong", "lastName": "Qiao" }, { "creatorType": "author", "firstName": "Chunhui", "lastName": "Wang" }, { "creatorType": "author", "firstName": "Feng", "lastName": "Jin" }, { "creatorType": "author", "firstName": "Dongying", "lastName": "Zheng" }, { "creatorType": "author", "firstName": "Caixia", "lastName": "Liu" } ], "abstractNote": "A human isoform of Collapsin Response Mediator Protein (CRMP) family proteins, CRMP-1, has been identified as a novel invasion suppressor. The aim of this study was to determine CRMP-1 expression pattern in placentas during normal pregnancy and elucidate the clinical significance of CRMP-1 expression in the placentas of women with early-onset preeclamptic pregnancies. We recruited 66 normal healthy pregnant Chinese women and 60 Chinese patients with preeclampsia [early-onset prereclampsia(ePE), n = 30 and late-onset preeclampsia(lPE) n = 30]. Gestational age-matched normal healthy pregnant women were used as controls of early-onset and late-onset preeclampsia, which were 23-33 + 6weeks, n = 18 and control B: 34-40 weeks, n = 20). Quantitative RT-PCR, Western blot analysis and immunohistochemistry were used to analyze the expressions of CRMP-1 in placentas. Expression of CRMP-1 was detected in syncytio- and cytotrophoblasts of all groups using immunohistochemistry. CRMP-1 was most abundantly expressed in syncytiotrophoblasts, moderately in cytotrophoblasts and the intermediate trophoblasts especially in the first trimester. The placental expression of CRMP-1 is particularly striking in the first trimester and decreases throughout pregnancy. There is a significant increase in CRMP-1 expression in the placenta of ePE but not of lPE, as compared to gestational-matched controls. The aberrant upregulation of CRMP-1 expression may link to the mechanism of developing ePE.", "publicationTitle": "Reproductive Sciences (Thousand Oaks, Calif.)", "publisher": "", "place": "", "date": "Sep 6, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Reprod Sci", "DOI": "10.1177/1933719114549847", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1933-7205", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25194153", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } }, { "key": "FAAQDFI2", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/FAAQDFI2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/FAAQDFI2", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/285989/items/KK3UXZ4V", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } } }, "data": { "key": "FAAQDFI2", "version": 2, "parentItem": "KK3UXZ4V", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2014-09-08T21:19:33Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/25193157", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } }, { "key": "KK3UXZ4V", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/KK3UXZ4V", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/KK3UXZ4V", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } }, "creatorSummary": "Bracken et al.", "parsedDate": "2014-09-05", "numChildren": 1 }, "data": { "key": "KK3UXZ4V", "version": 2, "itemType": "journalArticle", "title": "Induction of labour in pre-eclamptic women: a randomised trial comparing the Foley balloon catheter with oral misoprostol", "creators": [ { "creatorType": "author", "firstName": "Hillary", "lastName": "Bracken" }, { "creatorType": "author", "firstName": "Shuchita", "lastName": "Mundle" }, { "creatorType": "author", "firstName": "Brian", "lastName": "Faragher" }, { "creatorType": "author", "firstName": "Thomas", "lastName": "Easterling" }, { "creatorType": "author", "firstName": "Alan", "lastName": "Haycox" }, { "creatorType": "author", "firstName": "Mark", "lastName": "Turner" }, { "creatorType": "author", "firstName": "Zarko", "lastName": "Alfirevic" }, { "creatorType": "author", "firstName": "Beverly", "lastName": "Winikoff" }, { "creatorType": "author", "firstName": "Andrew", "lastName": "Weeks" } ], "abstractNote": "BACKGROUND: Between 40,000 and 80,000 pregnant women die annually from pre-eclampsia and eclampsia. Although magnesium sulphate and anti-hypertensive therapies can reduce the morbidity and mortality associated with pre-eclampsia, the only cure comes with delivery. Prompt delivery of the baby, preferably by vaginal route, is vital in order to achieve good maternal and neonatal outcomes. Induction of labour is therefore a critical intervention in order to prevent morbidity to both mother and baby. Two low cost interventions - oral misoprostol tablets and transcervical Foley catheterization - are already used by some in low resource settings, but their relative risks and benefits are not known. The trial will compare the risks, benefits, and trade-offs in efficacy, safety, acceptability and cost of misoprostol and Foley catheter for induction in women with preeclampsia or uncontrolled hypertension.\nMETHODS: A total of 602 women with an ongoing pregnancy with a live fetus requiring delivery because of pre-eclampsia or uncontrolled hypertension will be randomly assigned to labor induction with a transcervical Foley catheter or oral misoprostol 25 micrograms. Women will be recruited at two hospitals in Nagpur, India. The misoprostol group will receive oral misoprostol 25 microgram every 2 hours for a maximum of 12 doses or until active labor commences. The Foley group will undergo induction using a Foley catheter (silicone, size 18 F with 30 ml balloon) which will remain until active labor starts, the Foley catheter falls out, or 12 hours have elapsed. The primary outcome will be the attainment of vaginal delivery within 24 hours. Providers administering the treatment and those assessing the outcomes will not be blinded to group assignment.Trial registration: NCT01801410 (ClinicalTrials.gov).", "publicationTitle": "BMC pregnancy and childbirth", "publisher": "", "place": "", "date": "Sep 5, 2014", "volume": "14", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "308", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "BMC Pregnancy Childbirth", "DOI": "10.1186/1471-2393-14-308", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1471-2393", "archive": "", "archiveLocation": "", "shortTitle": "Induction of labour in pre-eclamptic women", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25193157", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } }, { "key": "PISE5N8Z", "version": 2, "library": { "type": "group", "id": 285989, "name": "preeclampia", "links": { "alternate": { "href": "https://www.zotero.org/groups/preeclampia", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/285989/items/PISE5N8Z", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/preeclampia/items/PISE5N8Z", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2055923, "username": "johanmolero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/johanmolero", "type": "text/html" } } }, "creatorSummary": "Hillesund et al.", "parsedDate": "2014-09-06", "numChildren": 1 }, "data": { "key": "PISE5N8Z", "version": 2, "itemType": "journalArticle", "title": "Associations of adherence to the New Nordic Diet with risk of preeclampsia and preterm delivery in the Norwegian Mother and Child Cohort Study (MoBa)", "creators": [ { "creatorType": "author", "firstName": "Elisabet Rudjord", "lastName": "Hillesund" }, { "creatorType": "author", "firstName": "Nina C.", "lastName": "Overby" }, { "creatorType": "author", "firstName": "Stephanie M.", "lastName": "Engel" }, { "creatorType": "author", "firstName": "Kari", "lastName": "Klungsøyr" }, { "creatorType": "author", "firstName": "Quaker E.", "lastName": "Harmon" }, { "creatorType": "author", "firstName": "Margaretha", "lastName": "Haugen" }, { "creatorType": "author", "firstName": "Elling", "lastName": "Bere" } ], "abstractNote": "Preeclampsia and preterm delivery are serious complications of pregnancy and leading causes of perinatal mortality and morbidity worldwide. Dietary factors might be associated with these adverse outcomes. We investigated whether adherence to the New Nordic Diet (NND) was associated with preeclampsia and preterm delivery risks in the Norwegian Mother and Child Cohort Study (MoBa). Participants were recruited from all over Norway during the period 1999-2008. A previously constructed diet score assessing meal frequency, and the consumption of Nordic fruits, root vegetables, cabbages, potatoes, oatmeal porridge, whole grains, wild fish, game, berries, milk and water, was used to assess NND adherence. Associations between NND adherence and the outcomes were estimated in adjusted multivariate logistic regression models. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated. A total of 72,072 women was included in the study. High versus low NND adherence was associated with lower risk of total preeclampsia (OR 0.86; 95 % CI 0.78-0.95) and early preeclampsia (OR 0.71; 95 % CI 0.52-0.96). High compared with low NND adherence was associated with a lower risk of spontaneous preterm delivery among nulliparous women (OR 0.77; 95 % CI 0.66-0.89), whereas multiparous women with high NND adherence had a marginally significant higher risk of preterm delivery (OR 1.24; 95 % CI 1.00-1.53). High NND adherence was associated with a lower relative risk of preeclampsia and of spontaneous preterm delivery among nulliparous women; however, among multiparous women there was a higher relative risk of preterm delivery.", "publicationTitle": "European Journal of Epidemiology", "publisher": "", "place": "", "date": "Sep 6, 2014", "volume": "", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Eur. J. Epidemiol.", "DOI": "10.1007/s10654-014-9948-6", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1573-7284", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ENG", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 25193741", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-09-08T21:19:33Z", "dateModified": "2014-09-08T21:19:33Z" } } ]