Aplicación de la Escala de conductas indicadoras de dolor en el paciente con trauma grave no comunicativo y ventilación mecanica - Gabriela Cordero
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Gabriela Cordero
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Gabriela Cordero
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(Spanish)", "creators": [ { "creatorType": "author", "firstName": "Y.", "lastName": "Fernández" }, { "creatorType": "author", "firstName": "A.", "lastName": "Acuña" }, { "creatorType": "author", "firstName": "M.", "lastName": "Carrabs" } ], "abstractNote": "This is a pharmaeconomic analysis of neuropathic pain treatment, particularly related to neuropathic diabetic pain, postherapetic neuralgia and trigeminal neuralgia, comparing carbamazepine, gabapentine and pregabaline. Neuropathic pain (NP) is originated in dysfunction of the central or peripheral nervous system. NP is actually a symptom and not a disease of difficult diagnosis, often associated to sleep alteration, weakness and depression. Cost-effectiveness analysis are presented as a ratio between the costs and the clinical effectiveness of a medical intervention. Additionally, the social impact of diabetic neuropathy is evaluated in this work in terms of productivity loses and its social cost. There is a tendency between health authorities to ask for the economic evaluation of any treatment or medical technique used to provide health; with the purpose of improving the use of the resources the health system have, and also considering the ethical aspects of any decision taken. In this study we searched information in Triptidatabase, Medline and Bireme. We included the studies in which patients showed >50% pain relieve. Additionally, the price at Venezuelan pharmacies of Carbamazepine (Tegretol®), Gabapentin (Neurotin®) and Pregabaline (Lyrica®) was taken into account. Our results demonstrate that in pain of postherpethic neuralgia and diabetic neuropathy, carbamazepine is the best in cost-effectiveness; pregabaline had the second place at 600 mg daily dose and resulted similar to gabapentin at 300 mg daily dose. In diabetic neuropathic pain, pergabaline and gabapentine showed similar results. Indirect social costs associated to productivity losses en Venezuela were estimated in 300 millions working hours per year, which are equivalent to 600 million US $. Due to poor quality of medical information available at Venezuela health centers, it was impossible to obtain information about the effectiveness and adverse events observed with the administered treatments. It is advisable in future studies to apply a quality of life questionnaire such as the SF-36. (English)", "publicationTitle": "PHARMAECONOMIC ANALYSIS OF CARBAMAZEPINE, GABAPENTINE AND PREGABALINE IN THE MANAGEMENT OF NEUROPHATIC PAIN. (English)", "publisher": "", "place": "", "date": "Junio 2009", "volume": "11", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "335-339", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Informe Medico", "DOI": "", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=a9h&AN=45526889&lang=es&site=ehost-live", "accessDate": "2014-08-17T03:03:26Z", "PMID": "", "PMCID": "", "ISSN": "13169688", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "ANALGESICS", "type": 1 }, { "tag": "CARBAMAZEPINE", "type": 1 }, { "tag": "Carbamazepina", "type": 1 }, { "tag": "Cost-effectiveness", "type": 1 }, { "tag": "Costo-efectividad", "type": 1 }, { "tag": "DIABETIC neuropathies -- Treatment", "type": 1 }, { "tag": "Dolor neuropático", "type": 1 }, { "tag": "Gabapentina", "type": 1 }, { "tag": "Gabapentine", "type": 1 }, { "tag": "Neuropathic pain", "type": 1 }, { "tag": "PAIN management", "type": 1 }, { "tag": "PERIPHERAL neuropathy", "type": 1 }, { "tag": "Pregabalina", "type": 1 }, { "tag": "Pregabaline", "type": 1 }, { "tag": "VENEZUELA", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-08-17T03:03:26Z", "dateModified": "2014-08-17T03:03:26Z" } }, { "key": "UEGKPZUF", "version": 42, "library": { "type": "group", "id": 278784, "name": "Dolor", "links": { "alternate": { "href": "https://www.zotero.org/groups/dolor", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/278784/items/UEGKPZUF", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dolor/items/UEGKPZUF", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/278784/items/TD8BJIBU", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2018422, "username": "Gaby Cordero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/gaby_cordero", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "UEGKPZUF", "version": 42, "parentItem": "TD8BJIBU", "itemType": "attachment", "linkMode": "imported_url", "title": "EBSCO Full Text", "accessDate": "2014-08-17T02:58:16Z", "url": "http://content.ebscohost.com/ContentServer.asp?T=P&P=AN&K=37012359&S=R&D=fua&EbscoContent=dGJyMNHX8kSep7Q4v%2BvlOLCmr0yeqLBSs6y4Sq6WxWXS&ContentCustomer=dGJyMPGvrlCvq7dLuePfgeyx44Dt6fIA", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Navas y Molino González - 2008 - Bases neuromédicas del dolor. (Spanish).pdf", "md5": "df3841279cc5eba9c6c0e07e0da4d9dd", "mtime": 1408244298018, "tags": [], "relations": {}, "dateAdded": "2014-08-17T02:58:16Z", "dateModified": "2014-08-17T02:58:18Z" } }, { "key": "TD8BJIBU", "version": 41, "library": { "type": "group", "id": 278784, "name": "Dolor", "links": { "alternate": { "href": "https://www.zotero.org/groups/dolor", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/278784/items/TD8BJIBU", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dolor/items/TD8BJIBU", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2018422, "username": "Gaby Cordero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/gaby_cordero", "type": "text/html" } } }, "creatorSummary": "Navas and Molino González", "parsedDate": "2008-11", "numChildren": 2 }, "data": { "key": "TD8BJIBU", "version": 41, "itemType": "journalArticle", "title": "Bases neuromédicas del dolor. (Spanish)", "creators": [ { "creatorType": "author", "firstName": "JOSÉ Ma. PEDRAJAS", "lastName": "Navas" }, { "creatorType": "author", "firstName": "Ángel M.", "lastName": "Molino González" } ], "abstractNote": "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such a damage. Pain can be classified by numerous criteria. If pain lasts at least three months, it is considered chronic pain, though the most important feature of chronic pain is its relation with cognitive and behavioural alterations. Nociceptors pick up pain sensations and send them up to the Central Nervous System through several stations. The first station is the dorsal root ganglia, the second station is the dorsal horn of the spinal cord, the third station consists of several sub-cortical structure (the thalamus being the most important), and finally the fourth station is the cerebral cortex, mainly somatosensorial, cingulus, insular and prefrontal areas. These structures are responsible for the perception of pain, for subconscious activities and for the modulatory, endocrine and emotional answers. The painful experience has three dimentions --sensitive-discriminative, cognitive, and emotional. A careful evaluation of pain is essential before prescribing analgesic drugs. A global planned strategy must be built to manage chronic pain --evaluating before treating, combining different methods of treatment, promoting ensuring therapeutic adherence, preventing adverse effects, working in a multidisciplinary team, gathering information, providing planification, systematically reviewing, and guaranteeing accesability, availability and flexibility. Drug treatment is based on the WHO's three-step analgesic ladder: the first step consists of non opioids analgesics (acetaminophen, non steroidantiinflamatories), the second consists of weak opioids (plus non opioid agents) and the third step consists of powerful opioids (plus non opioid agents). An adjuvant agent may be added at each step. In chronic pain, other non pharmacologic measures must be used -- physical, psychological and other measures such as radiation, surgery or radio frequency. (English)", "publicationTitle": "Neuro-medical bases of pain. (English)", "publisher": "", "place": "", "date": "Noviembre 2008", "volume": "19", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "277-293", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Clinica y Salud", "DOI": "", "citationKey": "", "url": "http://search.ebscohost.com/login.aspx?direct=true&db=fua&AN=37012359&lang=es&site=ehost-live", "accessDate": "2014-08-17T02:58:16Z", "PMID": "", "PMCID": "", "ISSN": "11305274", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "EBSCOhost", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "ANALGESICS", "type": 1 }, { "tag": "Adjuvant agents", "type": 1 }, { "tag": "Analgesic ladder", "type": 1 }, { "tag": "CENTRAL nervous system", "type": 1 }, { "tag": "CENTRAL nervous system depressants", "type": 1 }, { "tag": "CEREBRAL cortex", "type": 1 }, { "tag": "CHRONIC pain", "type": 1 }, { "tag": "Dolor crónico", "type": 1 }, { "tag": "Escalera analgésica", "type": 1 }, { "tag": "Experiencia dolorosa", "type": 1 }, { "tag": "Fármacos adyuvantes", "type": 1 }, { "tag": "Neuromodulación", "type": 1 }, { "tag": "Neuromodulation", "type": 1 }, { "tag": "Opiodes", "type": 1 }, { "tag": "Painful experience", "type": 1 }, { "tag": "SENSES & sensation", "type": 1 }, { "tag": "opioids", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-08-17T02:58:16Z", "dateModified": "2014-08-17T02:58:16Z" } }, { "key": "865U3IA3", "version": 39, "library": { "type": "group", "id": 278784, "name": "Dolor", "links": { "alternate": { "href": "https://www.zotero.org/groups/dolor", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/278784/items/865U3IA3", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dolor/items/865U3IA3", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2004340, "username": "Shambiux29", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/shambiux29", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "865U3IA3", "version": 39, "itemType": "attachment", "linkMode": "imported_file", "title": "DOLOR DOCUMENTO EN WORD.pdf", "accessDate": "", "url": "", "note": "", "contentType": "application/pdf", "charset": "", "filename": "DOLOR DOCUMENTO EN WORD.pdf", "md5": "31b0c067a813b4e1c5b9844f6b663c8c", "mtime": 1407866961880, "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-08-12T18:11:58Z", "dateModified": "2014-08-12T18:11:58Z" } }, { "key": "X4MN9UTH", "version": 35, "library": { "type": "group", "id": 278784, "name": "Dolor", "links": { "alternate": { "href": "https://www.zotero.org/groups/dolor", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/278784/items/X4MN9UTH", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/dolor/items/X4MN9UTH", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2018422, "username": "Gaby Cordero", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/gaby_cordero", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "X4MN9UTH", "version": 35, "itemType": "attachment", "linkMode": "imported_url", "title": "65087789.pdf", "accessDate": "2014-08-12T18:06:51Z", "url": "http://content.ebscohost.com/pdf25_26/pdf/2010/7KI/01Mar10/65087789.pdf?T=P&P=AN&K=65087789&S=R&D=a9h&EbscoContent=dGJyMNLr40Sep7A4v%2BvlOLCmr0yep7JSrqq4SbCWxWXS&ContentCustomer=dGJyMPGvrlCvq7dLuePfgeyx44Dt6fIA", "note": "
Opiodes en el manejo del dolor en la neuropatía diabética. (Gabriela Cordero)
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