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                    "lastName": "Lee"
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                    "firstName": "B",
                    "lastName": "Wanta"
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            "abstractNote": "CONTEXT: Co-occurring pain, fatigue, and sleep disturbance comprise a common symptom cluster in patients with cancer. Treatment approaches that target the cluster of symptoms rather than just a single symptom need to be identified and tested. OBJECTIVES: To synthesize evidence regarding mind-body interventions that have shown efficacy in treating two or more symptoms in the pain-fatigue-sleep disturbance cancer symptom cluster. METHODS: A literature search was conducted using CINAHL, Medline, and PsychInfo databases through March 2009. Studies were categorized based on the type of mind-body intervention (relaxation, imagery/hypnosis, cognitive-behavioral therapy/coping skills training [CBT/CST], meditation, music, and virtual reality), and a preliminary review was conducted with respect to efficacy for pain, fatigue, and sleep disturbance. Mind-body interventions were selected for review if there was evidence of efficacy for at least two of the three symptoms. Forty-three studies addressing five types of mind-body interventions met criteria and are summarized in this review. RESULTS: Imagery/hypnosis and CBT/CST interventions have produced improvement in all the three cancer-related symptoms individually: pain, fatigue, and sleep disturbance. Relaxation has resulted in improvements in pain and sleep disturbance. Meditation interventions have demonstrated beneficial effects on fatigue and sleep disturbance. Music interventions have demonstrated efficacy for pain and fatigue. No trials were found that tested the mind-body interventions specifically for the pain-fatigue-sleep disturbance symptom cluster. CONCLUSION: Efficacy studies are needed to test the impact of relaxation, imagery/hypnosis, CBT/CST, meditation, and music interventions in persons with cancer experiencing concurrent pain, fatigue, and sleep disturbance. These mind-body interventions could help patients manage all the symptoms in the cluster with a single treatment strategy. Copyright © 2010 by Elsevier Inc.",
            "publicationTitle": "Journal of Pain & Symptom Management",
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            "date": "2010",
            "volume": "39",
            "issue": "1",
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            "DOI": "10.1016/j.jpainsymman.2009.05.022",
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            "tags": [
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                    "tag": "Fatigue -- Etiology"
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            "abstractNote": "Objective: Insomnia is a common complaint among cancer survivors. Fortunately, cognitive-behavioral therapy for insomnia (CBT-I) has been shown to be an effective treatment in this population. However, it is rarely implemented given its limited availability. To address this barrier, we examined the ability of an easily accessible online CBT-I program to improve insomnia symptoms in cancer survivors. Methods: Twenty-eight cancer survivors with insomnia were randomly assigned to either an Internet insomnia intervention (n = 14) or to a waitlist control group (n = 14). The online program, Sleep Healthy Using The Internet, delivers the primary components of CBT-I (sleep restriction, stimulus control, cognitive restructuring, sleep hygiene, and relapse prevention). Pre- and post-assessment data were collected via online questionnaires and daily sleep diaries. Results: Participants in the Internet group showed significant improvements at post-assessment compared with those in the control group in overall insomnia severity (F(1,26) = 22.8; p<0.001), sleep efficiency (F(1,24) = 11.45; P = 0.002), sleep onset latency (F(1,24) = 5.18; P = 0.03), soundness of sleep (F(1,24) = 9.34; P = 0.005), restored feeling upon awakening (F(1,24) = 11.95; P = 0.002), and general fatigue (F(1,26) = 13.88; P = 0.001). Although other group x time interactions were not significant, overall adjusted effect sizes for all sleep variables as well as for fatigue, depression, anxiety, and quality of life ranged from small to large. Conclusions: CBT-I delivered through an interactive, individually tailored Internet intervention may be a viable treatment option for cancer survivors experiencing insomnia. Copyright © 2011 John Wiley & Sons, Ltd.",
            "publicationTitle": "Psychooncology",
            "publisher": "",
            "place": "",
            "date": "2012",
            "volume": "21",
            "issue": "7",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "695-705",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
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            "DOI": "10.1002/pon.1969",
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            "tags": [
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                    "tag": "Adult"
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                    "tag": "Clinical Trials"
                },
                {
                    "tag": "Cognitive Therapy"
                },
                {
                    "tag": "Cognitive Therapy -- Methods"
                },
                {
                    "tag": "Experimental Studies"
                },
                {
                    "tag": "Fatigue -- Psychosocial Factors"
                },
                {
                    "tag": "Fatigue -- Therapy"
                },
                {
                    "tag": "Female"
                },
                {
                    "tag": "Follow-Up Studies"
                },
                {
                    "tag": "Human"
                },
                {
                    "tag": "Humans"
                },
                {
                    "tag": "Insomnia -- Etiology"
                },
                {
                    "tag": "Insomnia -- Psychosocial Factors"
                },
                {
                    "tag": "Insomnia -- Therapy"
                },
                {
                    "tag": "Internet"
                },
                {
                    "tag": "Male"
                },
                {
                    "tag": "Middle Age"
                },
                {
                    "tag": "Middle Aged"
                },
                {
                    "tag": "Neoplasms"
                },
                {
                    "tag": "Neoplasms -- Complications"
                },
                {
                    "tag": "Neoplasms -- Psychosocial Factors"
                },
                {
                    "tag": "Neoplasms -- Therapy"
                },
                {
                    "tag": "Patient Education -- Methods"
                },
                {
                    "tag": "Patient Education as Topic"
                },
                {
                    "tag": "Prospective Studies"
                },
                {
                    "tag": "Quality of Life"
                },
                {
                    "tag": "Quality of Life -- Psychosocial Factors"
                },
                {
                    "tag": "Severity of Illness Index"
                },
                {
                    "tag": "Severity of Illness Indices"
                },
                {
                    "tag": "Sleep Initiation and Maintenance Disorders"
                },
                {
                    "tag": "Stress, Psychological"
                },
                {
                    "tag": "Survivors"
                },
                {
                    "tag": "Survivors -- Psychosocial Factors"
                },
                {
                    "tag": "Therapy, Computer Assisted -- Methods"
                },
                {
                    "tag": "Therapy, Computer-Assisted"
                },
                {
                    "tag": "Treatment Outcome"
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                {
                    "tag": "Treatment Outcomes"
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            "itemType": "journalArticle",
            "title": "Feasibility of a patient-controlled cognitive-behavioral intervention for pain, fatigue, and sleep disturbance in cancer",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "K L",
                    "lastName": "Kwekkeboom"
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                {
                    "creatorType": "author",
                    "firstName": "K",
                    "lastName": "Abbott-Anderson"
                },
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                    "firstName": "B",
                    "lastName": "Wanta"
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            ],
            "abstractNote": "Purpose/Objectives: To evaluate the feasibility of a patient-controlled cognitive-behavioral intervention for pain, fatigue, and sleep disturbance during treatment for advanced cancer and to assess initial efficacy of the intervention.Design: One group pre- and post-test design.Setting: Outpatient oncology clinics at a comprehensive cancer center in the midwestern United States.Sample: 30 adults with advanced (recurrent or metastatic) colorectal, lung, prostate, or gynecologic cancer receiving chemotherapy or radiotherapy.Methods: Participants completed baseline measures (e.g., demographics, symptom inventory) and received education and training to use an MP3 player loaded with 12 cognitive-behavioral strategies (e.g., relaxation exercises, guided imagery, nature sound recordings). Participants used the strategies as needed for symptom management for two weeks, keeping a log of symptom ratings with each use. Following the two-week intervention, participants completed a second symptom inventory and an evaluation of the intervention.Main Research Variables: Feasibility, patient-controlled cognitive-behavioral intervention, pain, fatigue, and sleep disturbance.Findings: Thirty of 43 eligible patients (73%) agreed to participate; of them, 27 (90%) completed the study. Most reported that they enjoyed the intervention, had learned useful skills, and perceived improvement in their symptoms. Symptom scores at two weeks did not differ significantly from baseline; however, significant reductions in pain, fatigue, and sleep disturbance severity were found in ratings made immediately before and after use of a cognitive-behavioral strategy.Conclusions: The patient-controlled cognitive-behavioral intervention appears to be feasible for additional study and could reduce day-to-day severity of co-occurring pain, fatigue, and sleep disturbance.Implications for Nursing: A randomized, controlled trial is needed to test efficacy of the intervention for co-occurring pain, fatigue, and sleep disturbance. Meanwhile, based on previous efficacy studies, cognitive-behavioral strategies can be recommended for certain individual symptoms.",
            "publicationTitle": "Oncology nursing forum",
            "publisher": "",
            "place": "",
            "date": "2010",
            "volume": "37",
            "issue": "3",
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            "partNumber": "",
            "partTitle": "",
            "pages": "E151-9",
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                },
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                    "tag": "Audiorecording -- Equipment and Supplies"
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                    "tag": "Cancer Care Facilities -- Midwestern United States"
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                    "tag": "Guided Imagery"
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                    "tag": "Human"
                },
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                    "tag": "Humans"
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                    "tag": "Imagery (Psychotherapy)"
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                    "tag": "Inferential Statistics"
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                    "tag": "Middle Aged"
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                    "tag": "Midwestern United States"
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                    "firstName": "H M",
                    "lastName": "Quah"
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                    "creatorType": "author",
                    "firstName": "A",
                    "lastName": "Samad"
                },
                {
                    "creatorType": "author",
                    "firstName": "A J",
                    "lastName": "Neathey"
                },
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                    "creatorType": "author",
                    "firstName": "D J",
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            "creatorSummary": "Bower et al.",
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            "itemType": "journalArticle",
            "title": "Yoga for persistent fatigue in breast cancer survivors: a randomized controlled trial",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "Julienne E",
                    "lastName": "Bower"
                },
                {
                    "creatorType": "author",
                    "firstName": "Deborah",
                    "lastName": "Garet"
                },
                {
                    "creatorType": "author",
                    "firstName": "Beth",
                    "lastName": "Sternlieb"
                },
                {
                    "creatorType": "author",
                    "firstName": "Patricia A",
                    "lastName": "Ganz"
                },
                {
                    "creatorType": "author",
                    "firstName": "Michael R",
                    "lastName": "Irwin"
                },
                {
                    "creatorType": "author",
                    "firstName": "Richard",
                    "lastName": "Olmstead"
                },
                {
                    "creatorType": "author",
                    "firstName": "Gail",
                    "lastName": "Greendale"
                }
            ],
            "abstractNote": "BACKGROUND\n\nCancer-related fatigue afflicts up to 33% of breast cancer survivors, yet there are no empirically validated treatments for this symptom.\n\n\nMETHODS\n\nThe authors conducted a 2-group randomized controlled trial to determine the feasibility and efficacy of an Iyengar yoga intervention for breast cancer survivors with persistent post-treatment fatigue. Participants were breast cancer survivors who had completed cancer treatments (other than endocrine therapy) at least 6 months before enrollment, reported significant cancer-related fatigue, and had no other medical conditions that would account for fatigue symptoms or interfere with yoga practice. Block randomization was used to assign participants to a 12-week, Iyengar-based yoga intervention or to 12 weeks of health education (control). The primary outcome was change in fatigue measured at baseline, immediately post-treatment, and 3 months after treatment completion. Additional outcomes included changes in vigor, depressive symptoms, sleep, perceived stress, and physical performance. Intent-to-treat analyses were conducted with all randomized participants using linear mixed models.\n\n\nRESULTS\n\nThirty-one women were randomly assigned to yoga (n = 16) or health education (n = 15). Fatigue severity declined significantly from baseline to post-treatment and over a 3-month follow-up in the yoga group relative to controls (P = .032). In addition, the yoga group had significant increases in vigor relative to controls (P = .011). Both groups had positive changes in depressive symptoms and perceived stress (P < .05). No significant changes in sleep or physical performance were observed.\n\n\nCONCLUSIONS\n\nA targeted yoga intervention led to significant improvements in fatigue and vigor among breast cancer survivors with persistent fatigue symptoms.",
            "publicationTitle": "Cancer",
            "publisher": "",
            "place": "",
            "date": "Aug 1, 2012",
            "volume": "118",
            "issue": "15",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "3766-3775",
            "series": "",
            "seriesTitle": "",
            "seriesText": "",
            "journalAbbreviation": "Cancer",
            "DOI": "10.1002/cncr.26702",
            "citationKey": "",
            "url": "",
            "accessDate": "",
            "PMID": "",
            "PMCID": "",
            "ISSN": "1097-0142",
            "archive": "",
            "archiveLocation": "",
            "shortTitle": "Yoga for persistent fatigue in breast cancer survivors",
            "language": "",
            "libraryCatalog": "NCBI PubMed",
            "callNumber": "",
            "rights": "",
            "extra": "PMID: 22180393",
            "tags": [
                {
                    "tag": "Attitude",
                    "type": 1
                },
                {
                    "tag": "Breast Neoplasms",
                    "type": 1
                },
                {
                    "tag": "Fatigue",
                    "type": 1
                },
                {
                    "tag": "Female",
                    "type": 1
                },
                {
                    "tag": "Humans",
                    "type": 1
                },
                {
                    "tag": "Middle Aged",
                    "type": 1
                },
                {
                    "tag": "Survivors",
                    "type": 1
                },
                {
                    "tag": "Treatment Outcome",
                    "type": 1
                },
                {
                    "tag": "Yoga",
                    "type": 1
                }
            ],
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            "name": "Dépistage détresse en oncologie",
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            },
            "creatorSummary": "Cramer et al.",
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        "data": {
            "key": "Z5NFJTZ7",
            "version": 60,
            "itemType": "journalArticle",
            "title": "Yoga for breast cancer patients and survivors: a systematic review and meta-analysis",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "H",
                    "lastName": "Cramer"
                },
                {
                    "creatorType": "author",
                    "firstName": "S",
                    "lastName": "Lange"
                },
                {
                    "creatorType": "author",
                    "firstName": "P",
                    "lastName": "Klose"
                },
                {
                    "creatorType": "author",
                    "firstName": "A",
                    "lastName": "Paul"
                },
                {
                    "creatorType": "author",
                    "firstName": "G",
                    "lastName": "Dobos"
                }
            ],
            "abstractNote": "BACKGROUND: Many breast cancer patients and survivors use yoga to cope with their disease. The aim of this review was to systematically assess and meta-analyze the evidence for effects of yoga on health-related quality of life and psychological health in breast cancer patients and survivors. METHODS: MEDLINE, PsycInfo, EMBASE, CAMBASE, and the Cochrane Library were screened through February 2012. Randomized controlled trials (RCTs) comparing yoga to controls were analyzed when they assessed health-related quality of life or psychological health in breast cancer patients or survivors. Risk of bias was assessed using the Cochrane risk of bias tool. Standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated. RESULTS: Twelve RCTs with a total of 742 participants were included. Seven RCTs compared yoga to no treatment; 3 RCTs compared yoga to supportive therapy; 1 RCT compared yoga to health education; and 1 RCT compared a combination of physiotherapy and yoga to physiotherapy alone. Evidence was found for short-term effects on global health-related quality of life (SMD = 0.62 [95% CI: 0.04 to 1.21]; P = 0.04), functional (SMD = 0.30 [95% CI: 0.03 to 0.57), social (SMD = 0.29 [95% CI: 0.08 to 0.50]; P < 0.01), and spiritual well-being (SMD = 0.41 [95% CI: 0.08; 0.74]; P = 0.01). These effects were, however, only present in studies with unclear or high risk of selection bias. Short-term effects on psychological health also were found: anxiety (SMD = -1.51 [95% CI: -2.47; -0.55]; P < 0.01), depression (SMD = -1.59 [95% CI: -2.68 to -0.51]; P < 0.01), perceived stress (SMD = -1.14 [95% CI:-2.16; -0.12]; P = 0.03), and psychological distress (SMD = -0.86 [95% CI:-1.50; -0.22]; P < 0.01). Subgroup analyses revealed evidence of efficacy only for yoga during active cancer treatment but not after completion of active treatment. CONCLUSIONS: This systematic review found evidence for short-term effects of yoga in improving psychological health in breast cancer patients. The short-term effects on health-related quality of life could not be clearly distinguished from bias. Yoga can be recommended as an intervention to improve psychological health during breast cancer treatment.",
            "publicationTitle": "BMC Cancer",
            "publisher": "",
            "place": "",
            "date": "2012",
            "volume": "12",
            "issue": "",
            "section": "",
            "partNumber": "",
            "partTitle": "",
            "pages": "412-412",
            "series": "",
            "seriesTitle": "",
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            "journalAbbreviation": "",
            "DOI": "10.1186/1471-2407-12-412",
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            "url": "Disponible sur le site web de la bibliothèque de HMR",
            "accessDate": "",
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            "PMCID": "",
            "ISSN": "1471-2407 (Electronic) 1471-2407 (Linking)",
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            "callNumber": "0002",
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        "version": 33,
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            "name": "Dépistage détresse en oncologie",
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            "creatorSummary": "C and Ancoli-Israel S",
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        "data": {
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            "version": 33,
            "itemType": "journalArticle",
            "title": "Does Effective Management of Sleep Disorders Reduce Cancer-Related Fatigue?",
            "creators": [
                {
                    "creatorType": "author",
                    "firstName": "",
                    "lastName": "C"
                },
                {
                    "creatorType": "author",
                    "firstName": "Sonia",
                    "lastName": "Ancoli-Israel S"
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            ],
            "abstractNote": "Cancer and cancer therapy are often associated with symptoms such as fatigue and sleep disturbances, before, during and after therapy. These symptoms of fatigue and poor sleep often occur in parallel having a significant impact on the physical functioning of patients with cancer. A strong correlation between cancer-related fatigue (CRF) and sleep has been observed in several studies, suggesting that they may be reciprocally related. The co-clustering of these symptoms suggests that they may have similar underlying aetiology and that treatments targeting either symptom may positively affect the other. Studies examining these clusters have shown that these symptoms often co-vary together. The potential mechanisms that link the relationship between insomnia and CRF are intriguing but require further investigation. Despite the high prevalence of insomnia and the often bidirectional relationship between poor sleep and fatigue, there are limited data to support the use of sleep management interventions as a means to reduce fatigue in patients with cancer. Assessment of the available evidence across trials is complicated by different study designs, patient selection criteria, stage of cancer treatment and by the nature of the interventions studied. Improvements from baseline in both sleep parameters and CRF have been documented in a limited number of studies, including two randomizedcontrolled trials using cognitive behavioural therapy for insomnia (CBT-I). In contrast, the efficacy of pharmacological therapies in reducing both insomnia and CRF is largely lacking. Clearly, treating clinically significant insomnia is likely to have benefits for the patient with cancer and for those who are recovering from cancer. In particular, pharmacotherapies for insomnia, singly or in combination with CBT-I, should be evaluated in multicentre randomized clinical trials to examine their efficacy in improving sleep quality and reducing associated CRF.",
            "publicationTitle": "Drugs",
            "publisher": "",
            "place": "",
            "date": "2009",
            "volume": "69",
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            "partNumber": "",
            "partTitle": "",
            "pages": "29-41",
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            "DOI": "10.2165/11531140-000000000-00000",
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            "callNumber": "0012",
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            "tags": [
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                    "tag": "Behavior Therapy"
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                    "tag": "Cancer Fatigue -- Prevention and Control"
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                    "type": 1
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                {
                    "tag": "United States"
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                {
                    "tag": "drug therapy"
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                {
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