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Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities]", "creators": [ { "creatorType": "author", "firstName": "M.", "lastName": "Ardenne" }, { "creatorType": "author", "firstName": "P. G.", "lastName": "Reitnauer" } ], "abstractNote": "A report is given on the recent discovery of outstanding immunological properties in BA 1 [N-(2-cyanoethylene)-urea] having a (low) molecular mass M = 111.104. Experiments in 214 DS carcinosarcoma bearing Wistar rats have shown that BA 1, at a dosage of only about 12 percent LD50 (150 mg kg) and negligible lethality (1.7 percent), results in a recovery rate of 40 percent without hyperglycemia and, in one test, of 80 percent with hyperglycemia. Under otherwise unchanged conditions the reference substance ifosfamide (IF) -- a further development of cyclophosphamide -- applied without hyperglycemia in its most efficient dosage of 47 percent LD50 (150 mg kg) brought about a recovery rate of 25 percent at a lethality of 18 percent. (Contrary to BA 1, 250-min hyperglycemia caused no further improvement of the recovery rate.) However this comparison is characterized by the fact that both substances exhibit two quite different (complementary) mechanisms of action. Leucocyte counts made after application of the said cancerostatics and dosages have shown a pronounced stimulation with BA 1 and with ifosfamide, the known suppression in the post-therapeutic interval usually found with standard cancerostatics. In combination with the cited plaque test for BA 1, blood pictures then allow conclusions on the immunity status. Since IF can be taken as one of the most efficient cancerostatics--there is no other chemotherapeutic known up to now that has a more significant effect on the DS carcinosarcoma in rats -- these findings are of special importance. Finally, the total amount of leucocytes and lymphocytes as well as their time behaviour was determined from the blood picture of tumour-free rats after i.v. application of BA 1. The thus obtained numerical values clearly show that further research work on the prophylactic use of this substance seems to be necessary and very promising.", "publicationTitle": "Arzneimittel-Forschung", "publisher": "", "place": "", "date": "Sep 1975", "volume": "25", "issue": "9", "section": "", "partNumber": "", "partTitle": "", "pages": "1369-1379", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Arzneimittelforschung", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "22", "PMCID": "", "ISSN": "0004-4172", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "ger", "libraryCatalog": "PubMed", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Animals", "type": 1 }, { "tag": "Antineoplastic Agents", "type": 1 }, { "tag": "Carcinosarcoma", "type": 1 }, { "tag": "Cyclophosphamide", "type": 1 }, { "tag": "Drug Evaluation, Preclinical", "type": 1 }, { "tag": "Drug Tolerance", "type": 1 }, { "tag": "Erythrocyte Count", "type": 1 }, { "tag": "Hydrogen-Ion Concentration", "type": 1 }, { "tag": "Hyperglycemia", "type": 1 }, { "tag": "Ifosfamide", "type": 1 }, { "tag": "Immunity", "type": 1 }, { "tag": "Immunosuppression", "type": 1 }, { "tag": "Lethal Dose 50", "type": 1 }, { "tag": "Leukocyte Count", "type": 1 }, { "tag": "Male", "type": 1 }, { "tag": "Mice", "type": 1 }, { "tag": "Neoplasms, Experimental", "type": 1 }, { "tag": "Rats", "type": 1 }, { "tag": "Stimulation, Chemical", "type": 1 }, { "tag": "Time Factors", "type": 1 }, { "tag": "Urea", "type": 1 } ], "collections": [ "7QZXM5UA" ], "relations": {}, "dateAdded": "2015-11-19T14:12:01Z", "dateModified": "2015-11-19T14:12:01Z" } }, { "key": "E5ZDFNNS", "version": 5263, "library": { "type": "group", "id": 27355, "name": "AIU Training", "links": { "alternate": { "href": "https://www.zotero.org/groups/aiu_training", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/27355/items/E5ZDFNNS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/aiu_training/items/E5ZDFNNS", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/27355/items/6PX8BJ7X", "type": "application/json" } }, "meta": { "createdByUser": { "id": 2775654, "username": "Lee kh", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lee_kh", "type": "text/html" } } } }, "data": { "key": "E5ZDFNNS", "version": 5263, "parentItem": "6PX8BJ7X", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2015-11-19T14:12:01Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2015-11-19T14:12:01Z", "dateModified": "2015-11-19T14:12:01Z" } }, { "key": "48NW8FM4", "version": 5275, "library": { "type": "group", "id": 27355, "name": "AIU Training", "links": { "alternate": { "href": "https://www.zotero.org/groups/aiu_training", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/27355/items/48NW8FM4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/aiu_training/items/48NW8FM4", "type": "text/html" } }, "meta": { "createdByUser": { "id": 2775654, "username": "Lee kh", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lee_kh", "type": "text/html" } } }, "lastModifiedByUser": { "id": 4239, "username": "benbyerly", "name": "Ben Byerly, PhD", "links": { "alternate": { "href": "https://www.zotero.org/benbyerly", "type": "text/html" } } }, "creatorSummary": "Tunnicliff et al.", "parsedDate": "1976-04", "numChildren": 1 }, "data": { "key": "48NW8FM4", "version": 5275, "itemType": "journalArticle", "title": "Some properties of acetylcholinesterase from rat retina", "creators": [ { "creatorType": "author", "firstName": "G.", "lastName": "Tunnicliff" }, { "creatorType": "author", "firstName": "Y.", "lastName": "Tsukada" }, { "creatorType": "author", "firstName": "A.", "lastName": "Barbeau" } ], "abstractNote": "Acetylcholinesterase (AChE, EC 3.1.1.7) of rat retina was studied with respect to its kinetic and other properties, and a comparison was made with the enzyme from brain. The subcellular distribution of the retinal AChE showed that the enzyme was concentrated in the synaptosomal-mitochondrial fraction although in the brain the AChE was distributed more evenly between the fractions studied. The enzyme from both retina and brain was easily solubilised and exhibited a Km of the order of 10(-4) M. The pH optimum was 8.3-8.6 for the AChE from both tissues for both the soluble and particulate enzyme.", "publicationTitle": "Canadian Journal of Biochemistry", "publisher": "", "place": "", "date": "Apr 1976", "volume": "54", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "389-392", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Can. J. 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Table of Contents
1. Introduction
2. Further Arguments for Matthean Posteriority
3. Some Challenges for Matthean Posteriority
4. Conclusion
Bibliography
Index - See more at: http://www.bloomsbury.com/uk/matthean-posteriority-9780567364340

\n

 

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Scathing RBL review by Pheme Perkins

\n

RBL 10/2009

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This Ph.D. dissertation completed at the University of Wales Lampeter under D. P.  Davies joins the ranks of those scholars who reject the consensus framework on the  composition and dating of the Synoptic Gospels. In addition to insisting on apostolic  authorship, it presses for an early dating that would see the entire New Testament  completed prior to 70 C.E. Since this research is a second career project, its author boasts of  undergraduate qualifications in classics and mathematics as proving that he possesses a  more logical and historical sensibility than the majority of New Testament scholars  working on these topics today. Measured by academic work in theoretical physics, history  of science, and classics today, these assertions are not credible. Another standard rhetorical  ploy is to castigate even those who advocate alternate views with failure to devote  sufficient attention to early twentieth-century scholars such as J. Chapman (1937), G.  Edmundson (1913), E. Meyer (1923).  

Readers will have to slog through a fair amount of idiosyncratic terminology employed to  represent familiar hypotheses about Synoptic relationships and graphical representations  that require constant rechecks to figure out

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\"Grew out of the Shaffer lectures delivered at the Yale Divinity School in February 1989\"--Pref

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Originally published: New York, N.Y. : E. Mellen, 1984, in series: Studies in the Bible and early Christianity

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Contents: Part I: The debate
\n
Part II: The reality of a premature death
\n
Part III: A ransom for many
\n
Part IV: Jesus and the Last supper -- Conclusions

\n
Part I: The Debate
\n
1 The Historical Jesus, the Death of Jesus, Historiography, and Theology, 3
\n
2 Jesus’ Death in Scholarship, 47
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3 Re-enter Jesus’ Death, 77
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Part II: The reality of a Premature Death
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4 The leading Food in the Dance of Atonement, 105
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5 A Temporary Presence in God’s Providence, 121
\n
6 Jesus and the Prophetic Fate, 139
\n
 
\n
Part III: A Ransom for Many
\n
7. The Authenticity of the Ransom Saying, 159
\n
Excursus: The Son of man, 171
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8 Jesus and the Scripture Prophets, 177
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9 The Script for Jesus, 189
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10 Jesus and the Servant, 207
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11 The Passion Predictions, 225
\n
 
\n
Part IV: Jesus and the Last Supper
\n
12 Pesah in Jewish History, 243
\n
13 Pesah and the Last Supper, 259
\n
14 This Bread and This Cup, 275
\n
15 Jesus and the Covenant, 293
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16 “Poured Out” and Eschatology, 323
\n
17 Conclusions, 335
\n
 Excursus: Chasing Down Paul’s Theological Ship, 372
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Collection of texts partly published previously

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When did Jesus become the Messiah? -- Gospel of Mark: the crucified Messiah -- Gospel of Matthew: the Davidic Messiah -- Gospel of Luke (and Acts): the prophetic Messiah -- Gospel of John: the elusive Messiah -- Believing in the Messiah

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Contents:

\n

1. Introduction: Messiah in Judaism: Rethinking the Question (William Scott Green), 1
2. Wisdom Makes a Difference: Alternatives to “Messianic” Configurations (Burton L. Mack), 15
3. Salvation without and with a Messiah: Developing Beliefs in Writings Ascribed to Enoch (George W. E. Nickelsburg), 49
4. How the Authors of 1 and 2 Maccabees Treated the “Messianic” Promises (Jonathan A. Goldstein), 69
5. Messianism in the Maccabean Period (John J. Collins), 97
6. Waiting for the Messiah: The Spiritual Universe of the Qumran Covenanters (Shemaryahu Talmon), 111
7.  Philo and Messiah (Richard D. Hecht), 139
8. Messiah and Gospel (Teorge Macrae, S.J), 169
9. Christology in Marks’ Gospel (Howard Clark Kee), 187
10. The Question of the Messiah in 4 Ezra (Michael E. Stone), 209
11. From Jewish Messianology to Christian Christology: Some Caveats and Perspectives (J. H. Charlesworth), 225
12. Mishnah and Messiah (Jacob Neusner), 265

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