[ { "key": "W3IUIK6H", "version": 202, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/W3IUIK6H", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/W3IUIK6H", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "lastModifiedByUser": { "id": 10159, "username": "cmbarton", "name": "Michael Barton", "links": { "alternate": { "href": "https://www.zotero.org/cmbarton", "type": "text/html" } } }, "creatorSummary": "Hekler et al.", "parsedDate": "2013-10-01", "numChildren": 3 }, "data": { "key": "W3IUIK6H", "version": 202, "itemType": "journalArticle", "title": "Exploring Behavioral Markers of Long-Term Physical Activity Maintenance A Case Study of System Identification Modeling Within a Behavioral Intervention", "creators": [ { "creatorType": "author", "firstName": "Eric B.", "lastName": "Hekler" }, { "creatorType": "author", "firstName": "Matthew P.", "lastName": "Buman" }, { "creatorType": "author", "firstName": "Nikhil", "lastName": "Poothakandiyil" }, { "creatorType": "author", "firstName": "Daniel E.", "lastName": "Rivera" }, { "creatorType": "author", "firstName": "Joseph M.", "lastName": "Dzierzewski" }, { "creatorType": "author", "firstName": "Adrienne Aiken", "lastName": "Morgan" }, { "creatorType": "author", "firstName": "Christina S.", "lastName": "McCrae" }, { "creatorType": "author", "firstName": "Beverly L.", "lastName": "Roberts" }, { "creatorType": "author", "firstName": "Michael", "lastName": "Marsiske" }, { "creatorType": "author", "firstName": "Peter R.", "lastName": "Giacobbi" } ], "abstractNote": "Efficacious interventions to promote long-term maintenance of physical activity are not well understood. Engineers have developed methods to create dynamical system models for modeling idiographic (i.e., within-person) relationships within systems. In behavioral research, dynamical systems modeling may assist in decomposing intervention effects and identifying key behavioral patterns that may foster behavioral maintenance. The Active Adult Mentoring Program was a 16-week randomized controlled trial of a group-based, peer-delivered physical activity intervention targeting older adults. Time-intensive (i.e., daily) physical activity reports were collected throughout the intervention. We explored differential patterns of behavior among participants who received the active intervention (N = 34; 88% women, 64.1 ± 8.3 years of age) and either maintained 150 minutes/week of moderate to vigorous intensity physical activity (MVPA; n = 10) or did not (n = 24) at 18 months following the intervention period. We used dynamical systems modeling to explore whether key intervention components (i.e., self-monitoring, access to an exercise facility, behavioral initiation training, behavioral maintenance training) and theoretically plausible behavioral covariates (i.e., indoor vs. outdoor activity) predicted differential patterns of behavior among maintainers and nonmaintainers. We found that maintainers took longer to reach a steady-state of MVPA. At week 10 of the intervention, nonmaintainers began to drop whereas maintainers increased MVPA. Self-monitoring, behavioral initiation training, percentage of outdoor activity, and behavioral maintenance training, but not access to an exercise facility, were key variables that explained patterns of change among maintainers. Future studies should be conducted to systematically explore these concepts within a priori idiographic (i.e., N-of-1) experimental designs.", "publicationTitle": "Health Education & Behavior", "publisher": "", "place": "", "date": "2013-10-01", "volume": "40", "issue": "1 suppl", "section": "", "partNumber": "", "partTitle": "", "pages": "51S-62S", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Health Educ Behav", "DOI": "10.1177/1090198113496787", "citationKey": "", "url": "http://heb.sagepub.com/content/40/1_suppl/51S", "accessDate": "2014-01-30T18:09:01Z", "PMID": "24084400", "PMCID": "", "ISSN": "1090-1981, 1552-6127", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "en", "libraryCatalog": "heb.sagepub.com.demo.oonair.net", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Physical activity", "type": 1 }, { "tag": "dynamical systems", "type": 1 }, { "tag": "maintenance", "type": 1 }, { "tag": "system identification", 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adaptive, time-varying interventions. It is demonstrated that adaptive interventions constitute a form of feedback control system in the context of behavioral health. Consequently, drawing from ideas in control engineering has the potential to significantly inform the analysis, design, and implementation of adaptive interventions, leading to improved adherence, better management of limited resources, a reduction of negative effects, and overall more effective interventions. This article illustrates how to express an adaptive intervention in control engineering terms, and how to use this framework in a computer simulation to investigate the anticipated impact of intervention design choices on efficacy. The potential benefits of operationalizing decision rules based on control engineering principles are particularly significant for adaptive interventions that involve multiple components or address co-morbidities, situations that pose significant challenges to conventional clinical practice.", "publicationTitle": "Drug and Alcohol Dependence", "publisher": "", "place": "", "date": "May 2007", "volume": "88, Supplement 2", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "S31-S40", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Drug and Alcohol Dependence", "DOI": "10.1016/j.drugalcdep.2006.10.020", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0376871606004248", "accessDate": "2014-01-30T18:11:05Z", "PMID": "", "PMCID": "", "ISSN": "0376-8716", "archive": "", "archiveLocation": "", "shortTitle": "Using engineering control principles to inform the design of adaptive interventions", "language": "", 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"createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Griffin and Greene", "parsedDate": "1994", "numChildren": 1 }, "data": { "key": "2H5E2N2E", "version": 191, "itemType": "journalArticle", "title": "Social interaction and symptom sequences: A case study of orofacial bradykinesia exacerbation in Parkinson's disease during negative marital interaction", "creators": [ { "creatorType": "author", "firstName": "William A.", "lastName": "Griffin" }, { "creatorType": "author", "firstName": "Shannon M.", "lastName": "Greene" } ], "abstractNote": "This case study demonstrates the detrimental influence of negative marital interaction on orofacial bradykinesia and speech productivity in a 74-yr-old male patient with Parkinson's disease. An increase in bradykinesia symptoms followed a series of specific negative comments by the wife during a conversation; these symptoms showed partial reversal during a subsequent conversation with a lab assistant. The analytic method and data summary strategies used to determine this relationship are discussed relative to their possible utility for other disorders.", "publicationTitle": "Psychiatry: Interpersonal and Biological Processes", "publisher": "", "place": "", "date": "1994", "volume": "57", "issue": "3", "section": "", "partNumber": "", "partTitle": "", "pages": "269-274", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1943-281X(Electronic);0033-2747(Print)", "archive": "", "archiveLocation": "", "shortTitle": "Social interaction and symptom sequences", "language": "", "libraryCatalog": "APA PsycNET", "callNumber": "", "rights": "(c) 2012 APA, all rights reserved", "extra": "", "tags": [ { "tag": "*Marital Relations", "type": 1 }, { "tag": "*Parkinson's Disease", "type": 1 }, { "tag": "*Symptoms", "type": 1 }, { "tag": "Case Report", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-01-30T18:07:41Z", "dateModified": "2014-01-30T18:07:41Z" } }, { "key": "HKJGKCU2", "version": 189, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/HKJGKCU2", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/HKJGKCU2", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/243662/items/7PHW59EX", "type": "application/json" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } } }, "data": { "key": "HKJGKCU2", "version": 189, "parentItem": "7PHW59EX", "itemType": "attachment", "linkMode": "linked_url", "title": "APA PsycNET Snapshot", "accessDate": "2014-01-30T18:06:58Z", "url": "http://psycnet.apa.org.ezproxy1.lib.asu.edu/psycinfo/1998-02574-004", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-01-30T18:06:58Z", "dateModified": "2014-01-30T18:06:58Z" } }, { "key": "7PHW59EX", "version": 189, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/7PHW59EX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/7PHW59EX", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Greene and Griffin", "parsedDate": "1998", "numChildren": 1 }, "data": { "key": "7PHW59EX", "version": 189, "itemType": "journalArticle", "title": "Symptom study in context: Effects of marital quality on signs of Parkinson's disease during patient–spouse interaction", "creators": [ { "creatorType": "author", "firstName": "Shannon M.", "lastName": "Greene" }, { "creatorType": "author", "firstName": "William A.", "lastName": "Griffin" } ], "abstractNote": "Hypokinesia, the inability to initiate or maintain movement, represents one of the most disabling aspects of Parkinson's disease (PD), and displays intriguing moment-to-moment variability from environmental stressors. Correlates of orofacial hypokinesia (characteristics of spontaneous eye blink and speech) were coded from videotaped interactions for 17 PD patients (aged 58–83 yrs) in maritally distressed and nondistressed dyads. Significant changes occurred only for the patients in distressed relationships on the 2 strongest neurophysiologic measures of orofacial hypokinesia, rate and duration of spontaneous eye blink. Further analyses suggest 2 possible explanations for these temporal symptom changes. Distressed spouses may exacerbate symptoms by exposing the patient to negativity. Alternately, nondistressed spouses may compensate for the demands of the interactional task by assuming a greater share of the conversation relative to the patient's contribution.", "publicationTitle": "Psychiatry: Interpersonal and Biological Processes", "publisher": "", "place": "", "date": "1998", "volume": "61", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "35-45", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1943-281X(Electronic);0033-2747(Print)", "archive": "", "archiveLocation": "", "shortTitle": "Symptom study in context", "language": "", "libraryCatalog": "APA PsycNET", "callNumber": "", "rights": "(c) 2012 APA, all rights reserved", "extra": "", "tags": [ { "tag": "*Marital Relations", "type": 1 }, { "tag": "*Parkinson's Disease", "type": 1 }, { "tag": "*Symptoms", "type": 1 }, { "tag": "Patients", "type": 1 }, { "tag": "Spouses", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-01-30T18:06:58Z", "dateModified": "2014-01-30T18:06:58Z" } }, { "key": "BFTAQJNQ", "version": 187, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/BFTAQJNQ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/BFTAQJNQ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Griffin et al.", "parsedDate": "2008", "numChildren": 1 }, "data": { "key": "BFTAQJNQ", "version": 187, "itemType": "journalArticle", "title": "Agents, Modeling Processes, and the Allure of Prophecy", "creators": [ { "creatorType": "author", "firstName": "William A.", "lastName": "Griffin" }, { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "author", "firstName": "Werner", "lastName": "Callebaut" } ], "abstractNote": "", "publicationTitle": "Biological Theory", "publisher": "", "place": "", "date": "2008", "volume": "3", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "73–78", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "PhilPapers", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T18:02:46Z", "dateModified": "2014-01-30T18:02:46Z" } }, { "key": "RI93KDZA", "version": 187, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/RI93KDZA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/RI93KDZA", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/243662/items/BFTAQJNQ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } } }, "data": { "key": "RI93KDZA", "version": 187, "parentItem": "BFTAQJNQ", "itemType": "attachment", "linkMode": "linked_url", "title": "PhilPapers - Snapshot", "accessDate": "2014-01-30T18:02:46Z", "url": "http://philpapers.org/rec/WILAMP", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-01-30T18:02:46Z", "dateModified": "2014-01-30T18:02:46Z" } }, { "key": "PMTWQTP5", "version": 186, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/PMTWQTP5", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/PMTWQTP5", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler and Müller", "parsedDate": "2007", "numChildren": 0 }, "data": { "key": "PMTWQTP5", "version": 186, "itemType": "book", "title": "Modeling Biology: Structures, Behaviors, Evolution", "creators": [ { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "author", "firstName": "Gerd B.", "lastName": "Müller" } ], "abstractNote": "", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "2007", "publisher": "MIT Press", "place": "Cambridge, MA", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "numPages": "", "ISBN": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:59:30Z", "dateModified": "2014-01-30T18:01:12Z" } }, { "key": "5FCZCP6K", "version": 181, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/5FCZCP6K", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/5FCZCP6K", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler and Maienschein", "parsedDate": "2013", "numChildren": 0 }, "data": { "key": "5FCZCP6K", "version": 181, "itemType": "bookSection", "title": "Developmental evolution", "creators": [ { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "author", "firstName": "Jane", "lastName": "Maienschein" }, { "creatorType": "editor", "firstName": "Michael", "lastName": "Ruse" } ], "abstractNote": "", "bookTitle": "The Cambridge Encyclopedia of Darwin and Evolutionary Thought", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "2013", "publisher": "Cambridge University Press", "place": "Cambridge", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "pages": "375-382", "ISBN": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:57:00Z", "dateModified": "2014-01-30T17:59:11Z" } }, { "key": "VA28XA5R", "version": 177, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/VA28XA5R", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/VA28XA5R", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler and Maienschein", "parsedDate": "2009", "numChildren": 0 }, "data": { "key": "VA28XA5R", "version": 177, "itemType": "book", "title": "Form and Function in Developmental Evolution", "creators": [ { "creatorType": "editor", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "editor", "firstName": "Jane", "lastName": "Maienschein" } ], "abstractNote": "", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "2009", "publisher": "Cambridge University Press", "place": "Cambridge", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "numPages": "", "ISBN": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:55:10Z", "dateModified": "2014-01-30T17:56:15Z" } }, { "key": "XV8C896V", "version": 174, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/XV8C896V", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/XV8C896V", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler and Maienschein", "parsedDate": "2007", "numChildren": 0 }, "data": { "key": "XV8C896V", "version": 174, "itemType": "book", "title": "From Embryology to Evo Devo: A History of Developmental Evolution", "creators": [ { "creatorType": "editor", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "editor", "firstName": "Jane", "lastName": "Maienschein" } ], "abstractNote": "", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "2007", "publisher": "MIT Press", "place": "Cambridge, MA", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "numPages": "", "ISBN": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:54:04Z", "dateModified": "2014-01-30T17:54:51Z" } }, { "key": "4JS429ZJ", "version": 173, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/4JS429ZJ", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/4JS429ZJ", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler et al.", "parsedDate": "2013-03-01", "numChildren": 1 }, "data": { "key": "4JS429ZJ", "version": 173, "itemType": "journalArticle", "title": "Computational Perspectives in the History of Science: To the Memory of Peter Damerow", "creators": [ { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "author", "firstName": "Jane", "lastName": "Maienschein" }, { "creatorType": "author", "firstName": "Jürgen", "lastName": "Renn" } ], "abstractNote": "ABSTRACT Computational methods and perspectives can transform the history of science by enabling the pursuit of novel types of questions, dramatically expanding the scale of analysis (geographically and temporally), and offering novel forms of publication that greatly enhance access and transparency. This essay presents a brief summary of a computational research system for the history of science, discussing its implications for research, education, and publication practices and its connections to the open-access movement and similar transformations in the natural and social sciences that emphasize big data. It also argues that computational approaches help to reconnect the history of science to individual scientific disciplines.", "publicationTitle": "Isis", "publisher": "", "place": "", "date": "March 1, 2013", "volume": "104", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "119-130", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Isis", "DOI": "10.1086/669891", "citationKey": "", "url": "http://www.jstor.org/stable/10.1086/669891", "accessDate": "2014-01-30T17:52:13Z", "PMID": "", "PMCID": "", "ISSN": "0021-1753", "archive": "", "archiveLocation": "", "shortTitle": "Computational Perspectives in the History of Science", "language": "", "libraryCatalog": "JSTOR", "callNumber": "", "rights": "Copyright © 2013 The History of Science Society", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:52:13Z", "dateModified": "2014-01-30T17:52:26Z" } }, { "key": "UDFMK96N", "version": 173, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/UDFMK96N", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/UDFMK96N", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/243662/items/4JS429ZJ", "type": "application/json" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } } }, "data": { "key": "UDFMK96N", "version": 173, "parentItem": "4JS429ZJ", "itemType": "attachment", "linkMode": "linked_url", "title": "JSTOR Full Text PDF", "accessDate": "2014-01-30T17:52:13Z", "url": "http://www.jstor.org.ezproxy1.lib.asu.edu/stable/pdfplus/10.1086%2F669891.pdf?acceptTC=true", "note": "", "contentType": "application/pdf", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-01-30T17:52:13Z", "dateModified": "2014-01-30T17:52:13Z" } }, { "key": "NCPFMG2J", "version": 172, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/NCPFMG2J", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/NCPFMG2J", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/243662/items/HJE3XSPS", "type": "application/json" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } } }, "data": { "key": "NCPFMG2J", "version": 172, "parentItem": "HJE3XSPS", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Full Text PDF", "accessDate": "2014-01-30T17:50:47Z", "url": "http://www.sciencedirect.com.ezproxy1.lib.asu.edu/science/article/pii/S0012160607015552/pdfft?md5=b4cd58fd8ad40e2eb3ae3f91b6cd4488&pid=1-s2.0-S0012160607015552-main.pdf", "note": "", "contentType": "application/pdf", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-01-30T17:50:47Z", "dateModified": "2014-01-30T17:50:47Z" } }, { "key": "HJE3XSPS", "version": 172, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/HJE3XSPS", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/HJE3XSPS", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler and Davidson", "parsedDate": "2008-02-01", "numChildren": 2 }, "data": { "key": "HJE3XSPS", "version": 172, "itemType": "journalArticle", "title": "Boveri's long experiment: Sea urchin merogones and the establishment of the role of nuclear chromosomes in development", "creators": [ { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "author", "firstName": "Eric H.", "lastName": "Davidson" } ], "abstractNote": "Theodor Boveri's major intellectual contribution was his focus on the causality of nuclear chromosomal determinants for embryological development. His initial experimental attempt to demonstrate that the character of the developing embryo is determined by nuclear rather than cytoplasmic factors was launched in 1889. The experimental design was to fertilize enucleate sea urchin eggs with sperm of another species that produces a distinguishably different embryonic morphology. Boveri's “hybrid merogone” experiment provided what he initially thought was empirical evidence for the nuclear control of development. However, for subtle reasons, the data were not interpretable and the experiment was repeated and contested. At the end of his life, Boveri was finally able to explain the technical difficulties that had beset the original experiment. However, by 1902 Boveri had carried out his famous polyspermy experiments, which provided decisive evidence for the role of nuclear chromosomal determinants in embryogenesis. Here we present the history of the hybrid merogone experiment as an important case of conceptual reasoning paired with (often difficult) experimental approaches. We then trace the further history of the merogone and normal species hybrid approaches that this experiment had set in train, and review their results from the standpoint of current insights. The history of Boveri's hybrid merogone experiment suggests important lessons about the interplay between what we call “models”, the specific intellectual statements we conceive about how biology works, and the sometimes difficult task of generating experimental proof for these concepts.", "publicationTitle": "Developmental Biology", "publisher": "", "place": "", "date": "February 1, 2008", "volume": "314", "issue": "1", "section": "", "partNumber": "", "partTitle": "", "pages": "1-11", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Developmental Biology", "DOI": "10.1016/j.ydbio.2007.11.024", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0012160607015552", "accessDate": "2014-01-30T17:50:47Z", "PMID": "", "PMCID": "", "ISSN": "0012-1606", "archive": "", "archiveLocation": "", "shortTitle": "Boveri's long experiment", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Genomic control", "type": 1 }, { "tag": "Hybrid merogones", "type": 1 }, { "tag": "Sea urchin embryos", "type": 1 }, { "tag": "Species hybrids", "type": 1 } ], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:50:47Z", "dateModified": "2014-01-30T17:50:47Z" } }, { "key": "IG2II3AU", "version": 172, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/IG2II3AU", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/IG2II3AU", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/243662/items/HJE3XSPS", "type": "application/json" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } } }, "data": { "key": "IG2II3AU", "version": 172, "parentItem": "HJE3XSPS", "itemType": "attachment", "linkMode": "linked_url", "title": "ScienceDirect Snapshot", "accessDate": "2014-01-30T17:50:47Z", "url": "http://www.sciencedirect.com.ezproxy1.lib.asu.edu/science/article/pii/S0012160607015552", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2014-01-30T17:50:47Z", "dateModified": "2014-01-30T17:50:47Z" } }, { "key": "ARPHUWHG", "version": 171, "library": { "type": "group", "id": 243662, "name": "NIH Proposal II", "links": { "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/243662/items/ARPHUWHG", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/nih_proposal_ii/items/ARPHUWHG", "type": "text/html" } }, "meta": { "createdByUser": { "id": 119757, "username": "lauraswantek", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/lauraswantek", "type": "text/html" } } }, "creatorSummary": "Laubichler", "parsedDate": "2009", "numChildren": 0 }, "data": { "key": "ARPHUWHG", "version": 171, "itemType": "bookSection", "title": "Form and function in evo devo: a conceptual and historical analysis", "creators": [ { "creatorType": "author", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "editor", "firstName": "Manfred D.", "lastName": "Laubichler" }, { "creatorType": "editor", "firstName": "Jane", "lastName": "Maienschein" } ], "abstractNote": "", "bookTitle": "Form and Function in Developmental Evolution", "series": "", "seriesNumber": "", "volume": "", "numberOfVolumes": "", "edition": "", "date": "2009", "publisher": "Cambridge University Press", "place": "Cambridge", "originalDate": "", "originalPublisher": "", "originalPlace": "", "format": "", "pages": "10-46", "ISBN": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [], "relations": {}, "dateAdded": "2014-01-30T17:47:16Z", "dateModified": "2014-01-30T17:49:34Z" } } ]