[ { "key": "KH6K96CT", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/KH6K96CT", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/KH6K96CT", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/ECAXZ6DB", "type": "application/json" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } } }, "data": { "key": "KH6K96CT", "version": 161, "parentItem": "ECAXZ6DB", "itemType": "attachment", "linkMode": "imported_url", "title": "Snapshot", "accessDate": "2013-06-26T17:57:43Z", "url": "http://ije.oxfordjournals.org/content/22/6/1154.short", "note": "", "contentType": "text/html", "charset": "", "filename": "Rodrigues et al. - 1993 - Protective Effect of BCG against Tuberculous Menin.html", "md5": "ca4968ed8044d09efb5950e0feea0fb6", "mtime": 1372269480000, "tags": [], "relations": {}, "dateAdded": "2013-06-26T17:57:43Z", "dateModified": "2013-06-26T17:58:00Z" } }, { "key": "IC264IZX", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/IC264IZX", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/IC264IZX", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/ECAXZ6DB", "type": "application/json" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } } }, "data": { "key": "IC264IZX", "version": 161, "parentItem": "ECAXZ6DB", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2013-06-26T17:57:43Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/8144299", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-06-26T17:57:43Z", "dateModified": "2013-06-26T17:57:43Z" } }, { "key": "ECAXZ6DB", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/ECAXZ6DB", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/ECAXZ6DB", "type": "text/html" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } }, "creatorSummary": "Rodrigues et al.", "parsedDate": "1993-12-01", "numChildren": 2 }, "data": { "key": "ECAXZ6DB", "version": 161, "itemType": "journalArticle", "title": "Protective Effect of BCG against Tuberculous Meningitis and Miliary Tuberculosis: A Meta-Analysis", "creators": [ { "creatorType": "author", "firstName": "Laura C", "lastName": "Rodrigues" }, { "creatorType": "author", "firstName": "Vinod K", "lastName": "Diwan" }, { "creatorType": "author", "firstName": "Jeremy G", "lastName": "Wheeler" } ], "abstractNote": "The protective effect of BCG against tuberculosis (TB) estimated in randomized controlled trials and observational studies ranges from negative to dose to a 100%. One of the many explanations offered for this is that different immunological mechanisms may be associated with protective effect against different forms and sites of disease. In this investigation, we recalculated vaccine protective effect separately for pulmonary disease and for meningeal/miliary disease in randomized controlled trials and case-control studies, tested for heterogeneity in site-specific estimates of protective effect and calculated a summary measure when appropriate. We found protective effect against pulmonary disease to be heterogenous to a statistically significant degree, and thus we did not calculate a summary measure of protection. Protective effect against meningeal and miliary TB was higher than against pulmonary disease and, except for a single study with two cases only, appeared to be homogeneous. Summary BCG protective effect against miliary or meningeal TB in randomized controlled trials was 86% (95% confidence interval [Cl] 65, 95) and in case-control studies 75% (95% Cl: 61, 84). The fact that protective effect appeared to be homogeneous against meningitis and miliary TB but not against pulmonary disease may result from the fact that patients with meningitis are on average younger and thus less likely to have been exposed to atypical bacteria; to a waning of the protective effect of BCG; or from the diversity of mechanisms of pathogenesis of pulmonary disease, which can originate from reinfection, reactivation or primary progression.", "publicationTitle": "International Journal of Epidemiology", "publisher": "", "place": "", "date": "12/01/1993", "volume": "22", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "1154-1158", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Int. J. Epidemiol.", "DOI": "10.1093/ije/22.6.1154", "citationKey": "", "url": "http://ije.oxfordjournals.org/content/22/6/1154", "accessDate": "2013-06-26T17:57:43Z", "PMID": "", "PMCID": "", "ISSN": "0300-5771, 1464-3685", "archive": "", "archiveLocation": "", "shortTitle": "Protective Effect of BCG against Tuberculous Meningitis and Miliary Tuberculosis", "language": "en", "libraryCatalog": "ije.oxfordjournals.org", "callNumber": "", "rights": "", "extra": "PMID: 8144299", "tags": [], "collections": [ "I3ZTZW2B" ], "relations": {}, "dateAdded": "2013-06-26T17:57:43Z", "dateModified": "2013-06-26T17:57:43Z" } }, { "key": "GCXSGGT9", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/GCXSGGT9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/GCXSGGT9", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/MTG225ZA", "type": "application/json" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } } }, "data": { "key": "GCXSGGT9", "version": 161, "parentItem": "MTG225ZA", "itemType": "attachment", "linkMode": "imported_url", "title": "Snapshot", "accessDate": "2013-06-26T17:57:35Z", "url": "http://ije.oxfordjournals.org/content/22/6/1154.short", "note": "", "contentType": "text/html", "charset": "", "filename": "Rodrigues et al. - 1993 - Protective Effect of BCG against Tuberculous Menin.html", "md5": "73449f5842b0efd88d539a86e5113e44", "mtime": 1372269458000, "tags": [], "relations": {}, "dateAdded": "2013-06-26T17:57:35Z", "dateModified": "2013-06-26T17:57:38Z" } }, { "key": "BQTTMA6M", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/BQTTMA6M", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/BQTTMA6M", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/MTG225ZA", "type": "application/json" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } } }, "data": { "key": "BQTTMA6M", "version": 161, "parentItem": "MTG225ZA", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2013-06-26T17:57:35Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/8144299", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-06-26T17:57:35Z", "dateModified": "2013-06-26T17:57:35Z" } }, { "key": "MTG225ZA", "version": 161, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/MTG225ZA", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/MTG225ZA", "type": "text/html" } }, "meta": { "createdByUser": { "id": 900744, "username": "eee8um", "name": "Emily", "links": { "alternate": { "href": "https://www.zotero.org/eee8um", "type": "text/html" } } }, "creatorSummary": "Rodrigues et al.", "parsedDate": "1993-12-01", "numChildren": 2 }, "data": { "key": "MTG225ZA", "version": 161, "itemType": "journalArticle", "title": "Protective Effect of BCG against Tuberculous Meningitis and Miliary Tuberculosis: A Meta-Analysis", "creators": [ { "creatorType": "author", "firstName": "Laura C", "lastName": "Rodrigues" }, { "creatorType": "author", "firstName": "Vinod K", "lastName": "Diwan" }, { "creatorType": "author", "firstName": "Jeremy G", "lastName": "Wheeler" } ], "abstractNote": "The protective effect of BCG against tuberculosis (TB) estimated in randomized controlled trials and observational studies ranges from negative to dose to a 100%. One of the many explanations offered for this is that different immunological mechanisms may be associated with protective effect against different forms and sites of disease. In this investigation, we recalculated vaccine protective effect separately for pulmonary disease and for meningeal/miliary disease in randomized controlled trials and case-control studies, tested for heterogeneity in site-specific estimates of protective effect and calculated a summary measure when appropriate. We found protective effect against pulmonary disease to be heterogenous to a statistically significant degree, and thus we did not calculate a summary measure of protection. Protective effect against meningeal and miliary TB was higher than against pulmonary disease and, except for a single study with two cases only, appeared to be homogeneous. Summary BCG protective effect against miliary or meningeal TB in randomized controlled trials was 86% (95% confidence interval [Cl] 65, 95) and in case-control studies 75% (95% Cl: 61, 84). The fact that protective effect appeared to be homogeneous against meningitis and miliary TB but not against pulmonary disease may result from the fact that patients with meningitis are on average younger and thus less likely to have been exposed to atypical bacteria; to a waning of the protective effect of BCG; or from the diversity of mechanisms of pathogenesis of pulmonary disease, which can originate from reinfection, reactivation or primary progression.", "publicationTitle": "International Journal of Epidemiology", "publisher": "", "place": "", "date": "12/01/1993", "volume": "22", "issue": "6", "section": "", "partNumber": "", "partTitle": "", "pages": "1154-1158", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Int. J. Epidemiol.", "DOI": "10.1093/ije/22.6.1154", "citationKey": "", "url": "http://ije.oxfordjournals.org/content/22/6/1154", "accessDate": "2013-06-26T17:57:35Z", "PMID": "", "PMCID": "", "ISSN": "0300-5771, 1464-3685", "archive": "", "archiveLocation": "", "shortTitle": "Protective Effect of BCG against Tuberculous Meningitis and Miliary Tuberculosis", "language": "en", "libraryCatalog": "ije.oxfordjournals.org", "callNumber": "", "rights": "", "extra": "PMID: 8144299", "tags": [], "collections": [ "I3ZTZW2B" ], "relations": {}, "dateAdded": "2013-06-26T17:57:35Z", "dateModified": "2013-06-26T17:57:35Z" } }, { "key": "TAJTCHU4", "version": 160, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/TAJTCHU4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/TAJTCHU4", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/JCX4PW6D", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "TAJTCHU4", "version": 160, "parentItem": "JCX4PW6D", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Full Text PDF", "accessDate": "2013-04-30T17:54:27Z", "url": "http://www.sciencedirect.com/science?_ob=MiamiImageURL&_cid=271357&_user=709071&_pii=S0376738808002500&_check=y&_origin=article&_zone=toolbar&_coverDate=01-Jul-2008&view=c&originContentFamily=serial&wchp=dGLzVlt-zSkWz&md5=c8d6f3e0f8ad2c0adcc770cffea2eb41&pid=1-s2.0-S0376738808002500-main.pdf", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Paulose et al. - 2008 - Fabrication of mechanically robust, large area, po.pdf", "md5": "25c64ca5814aa25791a253da16df0b6b", "mtime": 1367344473000, "tags": [], "relations": {}, "dateAdded": "2013-04-30T17:54:27Z", "dateModified": "2013-04-30T17:54:33Z" } }, { "key": "4DNRQQ8S", "version": 160, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/4DNRQQ8S", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/4DNRQQ8S", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/JCX4PW6D", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "4DNRQQ8S", "version": 160, "parentItem": "JCX4PW6D", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Snapshot", "accessDate": "2013-04-30T17:54:27Z", "url": "http://www.sciencedirect.com/science/article/pii/S0376738808002500", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "S0376738808002500.html", "md5": "bf67f8040b3c2160ab7b06bd66ed7ff7", "mtime": 1367344468000, "tags": [], "relations": {}, "dateAdded": "2013-04-30T17:54:27Z", "dateModified": "2013-04-30T17:54:27Z" } }, { "key": "JCX4PW6D", "version": 159, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/JCX4PW6D", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/JCX4PW6D", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Paulose et al.", "parsedDate": "2008-07-01", "numChildren": 2 }, "data": { "key": "JCX4PW6D", "version": 159, "itemType": "journalArticle", "title": "Fabrication of mechanically robust, large area, polycrystalline nanotubular/porous TiO2 membranes", "creators": [ { "creatorType": "author", "firstName": "Maggie", "lastName": "Paulose" }, { "creatorType": "author", "firstName": "Lily", "lastName": "Peng" }, { "creatorType": "author", "firstName": "Ketul C.", "lastName": "Popat" }, { "creatorType": "author", "firstName": "Oomman K.", "lastName": "Varghese" }, { "creatorType": "author", "firstName": "Thomas J.", "lastName": "LaTempa" }, { "creatorType": "author", "firstName": "Ningzhong", "lastName": "Bao" }, { "creatorType": "author", "firstName": "Tejal A.", "lastName": "Desai" }, { "creatorType": "author", "firstName": "Craig A.", "lastName": "Grimes" } ], "abstractNote": "This work describes the fabrication of self-standing, mechanically robust, polycrystalline (anatase) TiO2 nanotube array membranes of uniform pore size distribution. The membranes are made as flat sheets with thicknesses ranging from approximately 4.4 μm to 1 mm. To evaluate biofiltration applications, we have used glucose, phenol-red, bovine serum albumin (BSA), and immunoglobulin (IgG) as model molecules for studying the diffusion characteristics through the nanotube array membranes. It is found that the natural log of the molecule diffusion coefficients scale linearly with molecular weight. To date, we have fabricated membranes up to 12.5 cm2, a size limited only by the processing equipment.", "publicationTitle": "Journal of Membrane Science", "publisher": "", "place": "", "date": "July 1, 2008", "volume": "319", "issue": "1–2", "section": "", "partNumber": "", "partTitle": "", "pages": "199-205", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Journal of Membrane Science", "DOI": "10.1016/j.memsci.2008.03.050", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0376738808002500", "accessDate": "2013-04-30T17:54:27Z", "PMID": "", "PMCID": "", "ISSN": "0376-7388", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Biofiltration", "type": 1 }, { "tag": "Diffusion", "type": 1 }, { "tag": "Membrane", "type": 1 }, { "tag": "Nanoporous", "type": 1 }, { "tag": "Nanotube", "type": 1 }, { "tag": "TiO2", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T17:54:27Z", "dateModified": "2013-04-30T17:54:27Z" } }, { "key": "3FCANFIR", "version": 158, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/3FCANFIR", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/3FCANFIR", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/DMBBIDZC", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "3FCANFIR", "version": 158, "parentItem": "DMBBIDZC", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2013-04-30T17:01:03Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/10911004", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-04-30T17:01:03Z", "dateModified": "2013-04-30T17:01:03Z" } }, { "key": "DMBBIDZC", "version": 158, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/DMBBIDZC", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/DMBBIDZC", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Shapiro et al.", "parsedDate": "2000-07-27", "numChildren": 1 }, "data": { "key": "DMBBIDZC", "version": 158, "itemType": "journalArticle", "title": "Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen", "creators": [ { "creatorType": "author", "firstName": "A M", "lastName": "Shapiro" }, { "creatorType": "author", "firstName": "J R", "lastName": "Lakey" }, { "creatorType": "author", "firstName": "E A", "lastName": "Ryan" }, { "creatorType": "author", "firstName": "G S", "lastName": "Korbutt" }, { "creatorType": "author", "firstName": "E", "lastName": "Toth" }, { "creatorType": "author", "firstName": "G L", "lastName": "Warnock" }, { "creatorType": "author", "firstName": "N M", "lastName": "Kneteman" }, { "creatorType": "author", "firstName": "R V", "lastName": "Rajotte" } ], "abstractNote": "BACKGROUND: Registry data on patients with type 1 diabetes mellitus who undergo pancreatic islet transplantation indicate that only 8 percent are free of the need for insulin therapy at one year.\nMETHODS: Seven consecutive patients with type 1 diabetes and a history of severe hypoglycemia and metabolic instability underwent islet transplantation in conjunction with a glucocorticoid-free immunosuppressive regimen consisting of sirolimus, tacrolimus, and daclizumab. Islets were isolated by ductal perfusion with cold, purified collagenase, digested and purified in xenoprotein-free medium, and transplanted immediately by means of a percutaneous transhepatic portal embolization.\nRESULTS: All seven patients quickly attained sustained insulin independence after transplantation of a mean (+/-SD) islet mass of 11,547+/-1604 islet equivalents per kilogram of body weight (median follow-up, 11.9 months; range, 4.4 to 14.9). All recipients required islets from two donor pancreases, and one required a third transplant from two donors to achieve sustained insulin independence. The mean glycosylated hemoglobin values were normal after transplantation in all recipients. The mean amplitude of glycemic excursions (a measure of fluctuations in blood glucose concentrations) was significantly decreased after the attainment of insulin independence (from 198+/-32 mg per deciliter [11.1+/-1.8 mmol per liter] before transplantation to 119+/-37 mg per deciliter [6.7+/-2.1 mmol per liter] after the first transplantation and 51+/-30 mg per deciliter [2.8+/-1.7 mmol per liter] after the attainment of insulin independence; P<0.001). There were no further episodes of hypoglycemic coma. Complications were minor, and there were no significant increases in lipid concentrations during follow-up.\nCONCLUSIONS: Our observations in patients with type 1 diabetes indicate that islet transplantation can result in insulin independence with excellent metabolic control when glucocorticoid-free immunosuppression is combined with the infusion of an adequate islet mass.", "publicationTitle": "The New England journal of medicine", "publisher": "", "place": "", "date": "Jul 27, 2000", "volume": "343", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "230-238", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "N. Engl. J. Med.", "DOI": "10.1056/NEJM200007273430401", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "0028-4793", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 10911004", "tags": [ { "tag": "Adult", "type": 1 }, { "tag": "Antibodies, Monoclonal", "type": 1 }, { "tag": "Antibodies, Monoclonal, Humanized", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "C-Peptide", "type": 1 }, { "tag": "Diabetes Mellitus, Type 1", "type": 1 }, { "tag": "Drug Therapy, Combination", "type": 1 }, { "tag": "Glucose Tolerance Test", "type": 1 }, { "tag": "Hemoglobin A, Glycosylated", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Immunoglobulin G", "type": 1 }, { "tag": "Immunosuppressive Agents", "type": 1 }, { "tag": "Insulin", "type": 1 }, { "tag": "Islets of Langerhans Transplantation", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Sirolimus", "type": 1 }, { "tag": "Tacrolimus", "type": 1 }, { "tag": "Transplantation Conditioning", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T17:01:03Z", "dateModified": "2013-04-30T17:01:03Z" } }, { "key": "3K76EZJI", "version": 157, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/3K76EZJI", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/3K76EZJI", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/8CWPS3VK", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "3K76EZJI", "version": 157, "parentItem": "8CWPS3VK", "itemType": "attachment", "linkMode": "linked_url", "title": "PubMed entry", "accessDate": "2013-04-30T17:00:34Z", "url": "http://www.ncbi.nlm.nih.gov/pubmed/22723582", "note": "", "contentType": "text/html", "charset": "", "tags": [], "relations": {}, "dateAdded": "2013-04-30T17:00:34Z", "dateModified": "2013-04-30T17:00:34Z" } }, { "key": "8CWPS3VK", "version": 157, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/8CWPS3VK", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/8CWPS3VK", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Barton et al.", "parsedDate": "2012-07", "numChildren": 1 }, "data": { "key": "8CWPS3VK", "version": 157, "itemType": "journalArticle", "title": "Improvement in outcomes of clinical islet transplantation: 1999-2010", "creators": [ { "creatorType": "author", "firstName": "Franca B", "lastName": "Barton" }, { "creatorType": "author", "firstName": "Michael R", "lastName": "Rickels" }, { "creatorType": "author", "firstName": "Rodolfo", "lastName": "Alejandro" }, { "creatorType": "author", "firstName": "Bernhard J", "lastName": "Hering" }, { "creatorType": "author", "firstName": "Stephen", "lastName": "Wease" }, { "creatorType": "author", "firstName": "Bashoo", "lastName": "Naziruddin" }, { "creatorType": "author", "firstName": "Jose", "lastName": "Oberholzer" }, { "creatorType": "author", "firstName": "Jon S", "lastName": "Odorico" }, { "creatorType": "author", "firstName": "Marc R", "lastName": "Garfinkel" }, { "creatorType": "author", "firstName": "Marlon", "lastName": "Levy" }, { "creatorType": "author", "firstName": "Francois", "lastName": "Pattou" }, { "creatorType": "author", "firstName": "Thierry", "lastName": "Berney" }, { "creatorType": "author", "firstName": "Antonio", "lastName": "Secchi" }, { "creatorType": "author", "firstName": "Shari", "lastName": "Messinger" }, { "creatorType": "author", "firstName": "Peter A", "lastName": "Senior" }, { "creatorType": "author", "firstName": "Paola", "lastName": "Maffi" }, { "creatorType": "author", "firstName": "Andrew", "lastName": "Posselt" }, { "creatorType": "author", "firstName": "Peter G", "lastName": "Stock" }, { "creatorType": "author", "firstName": "Dixon B", "lastName": "Kaufman" }, { "creatorType": "author", "firstName": "Xunrong", "lastName": "Luo" }, { "creatorType": "author", "firstName": "Fouad", "lastName": "Kandeel" }, { "creatorType": "author", "firstName": "Enrico", "lastName": "Cagliero" }, { "creatorType": "author", "firstName": "Nicole A", "lastName": "Turgeon" }, { "creatorType": "author", "firstName": "Piotr", "lastName": "Witkowski" }, { "creatorType": "author", "firstName": "Ali", "lastName": "Naji" }, { "creatorType": "author", "firstName": "Philip J", "lastName": "O'Connell" }, { "creatorType": "author", "firstName": "Carla", "lastName": "Greenbaum" }, { "creatorType": "author", "firstName": "Yogish C", "lastName": "Kudva" }, { "creatorType": "author", "firstName": "Kenneth L", "lastName": "Brayman" }, { "creatorType": "author", "firstName": "Meredith J", "lastName": "Aull" }, { "creatorType": "author", "firstName": "Christian", "lastName": "Larsen" }, { "creatorType": "author", "firstName": "Tom W H", "lastName": "Kay" }, { "creatorType": "author", "firstName": "Luis A", "lastName": "Fernandez" }, { "creatorType": "author", "firstName": "Marie-Christine", "lastName": "Vantyghem" }, { "creatorType": "author", "firstName": "Melena", "lastName": "Bellin" }, { "creatorType": "author", "firstName": "A M James", "lastName": "Shapiro" } ], "abstractNote": "OBJECTIVE: To describe trends of primary efficacy and safety outcomes of islet transplantation in type 1 diabetes recipients with severe hypoglycemia from the Collaborative Islet Transplant Registry (CITR) from 1999 to 2010.\nRESEARCH DESIGN AND METHODS: A total of 677 islet transplant-alone or islet-after-kidney recipients with type 1 diabetes in the CITR were analyzed for five primary efficacy outcomes and overall safety to identify any differences by early (1999-2002), mid (2003-2006), or recent (2007-2010) transplant era based on annual follow-up to 5 years.\nRESULTS: Insulin independence at 3 years after transplant improved from 27% in the early era (1999-2002, n = 214) to 37% in the mid (2003-2006, n = 255) and to 44% in the most recent era (2007-2010, n = 208; P = 0.006 for years-by-era; P = 0.01 for era alone). C-peptide ≥0.3 ng/mL, indicative of islet graft function, was retained longer in the most recent era (P < 0.001). Reduction of HbA(1c) and resolution of severe hypoglycemia exhibited enduring long-term effects. Fasting blood glucose stabilization also showed improvements in the most recent era. There were also modest reductions in the occurrence of adverse events. The islet reinfusion rate was lower: 48% by 1 year in 2007-2010 vs. 60-65% in 1999-2006 (P < 0.01). Recipients that ever achieved insulin-independence experienced longer duration of islet graft function (P < 0.001).\nCONCLUSIONS: The CITR shows improvement in primary efficacy and safety outcomes of islet transplantation in recipients who received transplants in 2007-2010 compared with those in 1999-2006, with fewer islet infusions and adverse events per recipient.", "publicationTitle": "Diabetes care", "publisher": "", "place": "", "date": "Jul 2012", "volume": "35", "issue": "7", "section": "", "partNumber": "", "partTitle": "", "pages": "1436-1445", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Diabetes Care", "DOI": "10.2337/dc12-0063", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "1935-5548", "archive": "", "archiveLocation": "", "shortTitle": "Improvement in outcomes of clinical islet transplantation", "language": "eng", "libraryCatalog": "NCBI PubMed", "callNumber": "", "rights": "", "extra": "PMID: 22723582", "tags": [ { "tag": "Adolescent", "type": 1 }, { "tag": "Adult", "type": 1 }, { "tag": "Aged", "type": 1 }, { "tag": "Blood Glucose", "type": 1 }, { "tag": "C-Peptide", "type": 1 }, { "tag": "Diabetes Mellitus, Type 1", "type": 1 }, { "tag": "Hemoglobin A, Glycosylated", "type": 1 }, { "tag": "Humans", "type": 1 }, { "tag": "Islets of Langerhans Transplantation", "type": 1 }, { "tag": "Middle Aged", "type": 1 }, { "tag": "Registries", "type": 1 }, { "tag": "Treatment Outcome", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T17:00:34Z", "dateModified": "2013-04-30T17:00:34Z" } }, { "key": "JXCZ2QAN", "version": 156, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/JXCZ2QAN", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/JXCZ2QAN", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/Z7UXF2VD", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "JXCZ2QAN", "version": 156, "parentItem": "Z7UXF2VD", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Snapshot", "accessDate": "2013-04-30T10:25:00Z", "url": "http://www.sciencedirect.com/science/article/pii/S0376738808002500", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "S0376738808002500.html", "md5": "49d810d16439e56e3d9f2d0c08789645", "mtime": 1367317501000, "tags": [], "relations": {}, "dateAdded": "2013-04-30T10:25:00Z", "dateModified": "2013-04-30T10:25:00Z" } }, { "key": "Z7UXF2VD", "version": 155, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/Z7UXF2VD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/Z7UXF2VD", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Paulose et al.", "parsedDate": "2008-07-01", "numChildren": 1 }, "data": { "key": "Z7UXF2VD", "version": 155, "itemType": "journalArticle", "title": "Fabrication of mechanically robust, large area, polycrystalline nanotubular/porous TiO2 membranes", "creators": [ { "creatorType": "author", "firstName": "Maggie", "lastName": "Paulose" }, { "creatorType": "author", "firstName": "Lily", "lastName": "Peng" }, { "creatorType": "author", "firstName": "Ketul C.", "lastName": "Popat" }, { "creatorType": "author", "firstName": "Oomman K.", "lastName": "Varghese" }, { "creatorType": "author", "firstName": "Thomas J.", "lastName": "LaTempa" }, { "creatorType": "author", "firstName": "Ningzhong", "lastName": "Bao" }, { "creatorType": "author", "firstName": "Tejal A.", "lastName": "Desai" }, { "creatorType": "author", "firstName": "Craig A.", "lastName": "Grimes" } ], "abstractNote": "This work describes the fabrication of self-standing, mechanically robust, polycrystalline (anatase) TiO2 nanotube array membranes of uniform pore size distribution. The membranes are made as flat sheets with thicknesses ranging from approximately 4.4 μm to 1 mm. To evaluate biofiltration applications, we have used glucose, phenol-red, bovine serum albumin (BSA), and immunoglobulin (IgG) as model molecules for studying the diffusion characteristics through the nanotube array membranes. It is found that the natural log of the molecule diffusion coefficients scale linearly with molecular weight. To date, we have fabricated membranes up to 12.5 cm2, a size limited only by the processing equipment.", "publicationTitle": "Journal of Membrane Science", "publisher": "", "place": "", "date": "July 1, 2008", "volume": "319", "issue": "1–2", "section": "", "partNumber": "", "partTitle": "", "pages": "199-205", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Journal of Membrane Science", "DOI": "10.1016/j.memsci.2008.03.050", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0376738808002500", "accessDate": "2013-04-30T10:25:00Z", "PMID": "", "PMCID": "", "ISSN": "0376-7388", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Biofiltration", "type": 1 }, { "tag": "Diffusion", "type": 1 }, { "tag": "Membrane", "type": 1 }, { "tag": "Nanoporous", "type": 1 }, { "tag": "Nanotube", "type": 1 }, { "tag": "TiO2", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T10:25:00Z", "dateModified": "2013-04-30T10:25:00Z" } }, { "key": "NNWDSFVV", "version": 154, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/NNWDSFVV", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/NNWDSFVV", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Chu et al.", "parsedDate": "2012-02-02", "numChildren": 0 }, "data": { "key": "NNWDSFVV", "version": 154, "itemType": "patent", "title": "High flux high efficiency nanofiber membranes and methods of production thereof", "creators": [ { "creatorType": "inventor", "firstName": "Benjamin", "lastName": "Chu" }, { "creatorType": "inventor", "firstName": "S. Benjamin", "lastName": "Hsiao" }, { "creatorType": "inventor", "firstName": "Hongyang", "lastName": "Ma" } ], "abstractNote": "A membrane is provided including a coating layer having cellulose nanofibers produced from oxidized cellulose microfibers and an electrospun substrate upon which the coating layer is applied. The nanofibers of the electrospun substrate have a diameter greater than that of the cellulose nanofibers. The membrane also has non-woven support upon which the electrospun substrate is disposed. Microfibers of the non-woven support have a diameter greater than that of the nanofibers of the electrospun substrate. Application of electrospun membrane is in microfiltration area, while the cellulose nanofiber membrane serves in ultrafiltration, nanofiltration, and reverse osmosis after chemical modification.", "place": "", "country": "", "assignee": "The Research Foundation Of State University Of New York", "issuingAuthority": "", "patentNumber": "WO2010042647 A9", "filingDate": "Oct 7, 2009", "pages": "", "applicationNumber": "", "priorityNumbers": "", "issueDate": "Feb 2, 2012", "priorityDate": "", "references": "", "legalStatus": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "shortTitle": "", "language": "", "rights": "", "extra": "International Classification: B01D69/10; B01D71/12\nU.S. Classification: B01D 71/12; B01D 67/00K; D01F 2/00; D01F 2/24; D01D 5/00E4D2; B01D 39/16B2; B01D 39/18; B01D 39/16B4", "tags": [], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T10:13:25Z", "dateModified": "2013-04-30T10:13:25Z" } }, { "key": "HIJECRZD", "version": 153, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/HIJECRZD", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/HIJECRZD", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/IFDJK62Q", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "HIJECRZD", "version": 153, "parentItem": "IFDJK62Q", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Snapshot", "accessDate": "2013-04-30T10:12:21Z", "url": "http://www.sciencedirect.com/science/article/pii/S0376738813002378", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "S0376738813002378.html", "md5": "fb9275a927c81700ff32835ced206002", "mtime": 1367316742000, "tags": [], "relations": {}, "dateAdded": "2013-04-30T10:12:21Z", "dateModified": "2013-04-30T10:12:21Z" } }, { "key": "IFDJK62Q", "version": 152, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/IFDJK62Q", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/IFDJK62Q", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Wei et al.", "parsedDate": "2013-08-01", "numChildren": 1 }, "data": { "key": "IFDJK62Q", "version": 152, "itemType": "journalArticle", "title": "Structure influence of hyperbranched polyester on structure and properties of synthesized nanofiltration membranes", "creators": [ { "creatorType": "author", "firstName": "Xiuzhen", "lastName": "Wei" }, { "creatorType": "author", "firstName": "Xin", "lastName": "Kong" }, { "creatorType": "author", "firstName": "Jia", "lastName": "Yang" }, { "creatorType": "author", "firstName": "Guoliang", "lastName": "Zhang" }, { "creatorType": "author", "firstName": "Jinyuan", "lastName": "Chen" }, { "creatorType": "author", "firstName": "Jiade", "lastName": "Wang" } ], "abstractNote": "Abstract \nNanofiltration (NF) membranes have been prepared by interfacial polymerization of hyperbranched polyester with different number of terminated hydroxyl groups and trimesol chloride (TMC). Surface morphology and chemical structure of the different membranes were characterized by Fourier transforms infrared spectrometry (FTIR-ATR), scanning electron microscopy (SEM), atom force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). Molecular weight cut-off (MWCO) and surface zeta potential of the NF membranes were evaluated. The effect of pH value, operation pressure and salt concentration on rejection properties were also assessed. Nanofiltration properties were determined with organic anionic and cationic simulated dye wastewater. It was found that all NF membranes surface presented negative charge and had a MWCO of 4–6 kDa. Rejection properties of the NF membranes were affected by the dye charges, dye concentration and salt concentration.", "publicationTitle": "Journal of Membrane Science", "publisher": "", "place": "", "date": "August 1, 2013", "volume": "440", "issue": "", "section": "", "partNumber": "", "partTitle": "", "pages": "67-76", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Journal of Membrane Science", "DOI": "10.1016/j.memsci.2013.03.034", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0376738813002378", "accessDate": "2013-04-30T10:12:21Z", "PMID": "", "PMCID": "", "ISSN": "0376-7388", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Anionic dye", "type": 1 }, { "tag": "Cationic dye", "type": 1 }, { "tag": "Dye removal", "type": 1 }, { "tag": "Hyperbranched polyester", "type": 1 }, { "tag": "Nanofiltration membranes", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T10:12:21Z", "dateModified": "2013-04-30T10:12:21Z" } }, { "key": "9A2N6SXU", "version": 151, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/9A2N6SXU", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/9A2N6SXU", "type": "text/html" } }, "meta": { "createdByUser": { "id": 530072, "username": "JessKanwal", "name": "", "links": { "alternate": { "href": "https://www.zotero.org/jesskanwal", "type": "text/html" } } }, "creatorSummary": "Zoppe et al.", "parsedDate": "2009-08-15", "numChildren": 0 }, "data": { "key": "9A2N6SXU", "version": 151, "itemType": "journalArticle", "title": "Reinforcing Poly(ε-caprolactone) Nanofibers with Cellulose Nanocrystals", "creators": [ { "creatorType": "author", "firstName": "Justin", "lastName": "Zoppe" }, { "creatorType": "author", "firstName": "Maria", "lastName": "Peresin" }, { "creatorType": "author", "firstName": "Youssef", "lastName": "Habibi" }, { "creatorType": "author", "firstName": "Richard", "lastName": "Venditti" }, { "creatorType": "author", "firstName": "Orlando", "lastName": "Rojas" } ], "abstractNote": "", "publicationTitle": "", "publisher": "", "place": "", "date": "august 15, 2009", "volume": "1", "issue": "9", "section": "", "partNumber": "", "partTitle": "", "pages": "", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "", "citationKey": "", "url": "", "accessDate": "", "PMID": "", "PMCID": "", "ISSN": "", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "", "callNumber": "", "rights": "", "extra": "", "tags": [], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T09:47:27Z", "dateModified": "2013-04-30T09:49:45Z" } }, { "key": "34FRUW8Z", "version": 147, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/34FRUW8Z", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/34FRUW8Z", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/3ARM8EW9", "type": "application/json" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } } }, "data": { "key": "34FRUW8Z", "version": 147, "parentItem": "3ARM8EW9", "itemType": "attachment", "linkMode": "imported_url", "title": "Snapshot", "accessDate": "2013-04-30T08:21:20Z", "url": "http://onlinelibrary.wiley.com/doi/10.1002/app.26949/abstract", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "abstract.html", "md5": "e6654d5749b4ee2e8c26b2c13f6e6480", "mtime": 1367310081000, "tags": [], "relations": {}, "dateAdded": "2013-04-30T08:21:20Z", "dateModified": "2013-04-30T08:21:20Z" } }, { "key": "3ARM8EW9", "version": 146, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/3ARM8EW9", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/3ARM8EW9", "type": "text/html" } }, "meta": { "createdByUser": { "id": 346010, "username": "ems2bp", "name": "Elaine Schertz", "links": { "alternate": { "href": "https://www.zotero.org/ems2bp", "type": "text/html" } } }, "creatorSummary": "Ghasemi-Mobarakeh et al.", "parsedDate": "2007", "numChildren": 1 }, "data": { "key": "3ARM8EW9", "version": 146, "itemType": "journalArticle", "title": "A novel method for porosity measurement of various surface layers of nanofibers mat using image analysis for tissue engineering applications", "creators": [ { "creatorType": "author", "firstName": "L.", "lastName": "Ghasemi-Mobarakeh" }, { "creatorType": "author", "firstName": "D.", "lastName": "Semnani" }, { "creatorType": "author", "firstName": "M.", "lastName": "Morshed" } ], "abstractNote": "Research in polymer nanofibers has undergone significant progress in the last decade. One of the main driving force for this progress is the increasing use of these polymer nanofibers for tissue engineering. Adequate porosity and surface area are widely recognized as important parameters in the design of scaffolds for tissue engineering and therefore measurement of porosity is very important. Previous methods such as mercury measurement, indirect method, the porosity measurement based on density of nanofibers do not measure the porosity of various surface layers. The goal of this study is measurement of porosity of various surface layers of scaffold. Image analysis was used for this purpose. SEM images of nanofibers mat were converted to binary images using different thresholds and porosity of scaffold was measured in various layers. On the basis of the results of our study, this method can be applied to porosity measurement of various surface layers of nanofibers mat. The results showed that porosity of various surface layers is related to the number of layers of nanofibers mat. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007", "publicationTitle": "Journal of Applied Polymer Science", "publisher": "", "place": "", "date": "2007", "volume": "106", "issue": "4", "section": "", "partNumber": "", "partTitle": "", "pages": "2536–2542", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "", "DOI": "10.1002/app.26949", "citationKey": "", "url": "http://onlinelibrary.wiley.com/doi/10.1002/app.26949/abstract", "accessDate": "2013-04-30T08:21:20Z", "PMID": "", "PMCID": "", "ISSN": "1097-4628", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "en", "libraryCatalog": "Wiley Online Library", "callNumber": "", "rights": "Copyright © 2007 Wiley Periodicals, Inc.", "extra": "", "tags": [ { "tag": "fibers", "type": 1 }, { "tag": "image analysis", "type": 1 }, { "tag": "nanotechnology", "type": 1 }, { "tag": "porosity", "type": 1 }, { "tag": "scaffold", "type": 1 }, { "tag": "tissue engineering", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-30T08:21:20Z", "dateModified": "2013-04-30T08:21:20Z" } }, { "key": "KZVKZ58E", "version": 145, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/KZVKZ58E", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/KZVKZ58E", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/ANPP9PQI", "type": "application/json" } }, "meta": { "createdByUser": { "id": 903888, "username": "mhb3bh", "name": "Mia", "links": { "alternate": { "href": "https://www.zotero.org/mhb3bh", "type": "text/html" } } } }, "data": { "key": "KZVKZ58E", "version": 145, "parentItem": "ANPP9PQI", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Snapshot", "accessDate": "2013-04-29T22:54:29Z", "url": "http://www.sciencedirect.com/science/article/pii/S0142961211002389", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "S0142961211002389.html", "md5": "d7ef38b4581513d8cdc9008246b9ae09", "mtime": 1367276071121, "tags": [], "relations": {}, "dateAdded": "2013-04-29T22:59:10Z", "dateModified": "2013-04-29T22:59:10Z" } }, { "key": "5RMTZXN7", "version": 145, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/5RMTZXN7", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/5RMTZXN7", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/ANPP9PQI", "type": "application/json" } }, "meta": { "createdByUser": { "id": 903888, "username": "mhb3bh", "name": "Mia", "links": { "alternate": { "href": "https://www.zotero.org/mhb3bh", "type": "text/html" } } }, "numChildren": 0 }, "data": { "key": "5RMTZXN7", "version": 145, "parentItem": "ANPP9PQI", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Full Text PDF", "accessDate": "2013-04-29T22:54:18Z", "url": "http://www.sciencedirect.com/science?_ob=MiamiImageURL&_cid=271870&_user=709071&_pii=S0142961211002389&_check=y&_origin=article&_zone=toolbar&_coverDate=30-Sep-2011&view=c&originContentFamily=serial&wchp=dGLzVlS-zSkWz&md5=1e2d1bbda5e593af89565daab68ad060&pid=1-s2.0-S0142961211002389-main.pdf", "note": "", "contentType": "application/pdf", "charset": "", "filename": "Vériter et al. - 2011 - The impact of hyperglycemia and the presence of en.pdf", "md5": "e8d0068bf92a9510789535610f3467d0", "mtime": 1367276067173, "tags": [], "relations": {}, "dateAdded": "2013-04-29T22:59:10Z", "dateModified": "2013-04-29T22:59:10Z" } }, { "key": "ANPP9PQI", "version": 144, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/ANPP9PQI", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/ANPP9PQI", "type": "text/html" } }, "meta": { "createdByUser": { "id": 903888, "username": "mhb3bh", "name": "Mia", "links": { "alternate": { "href": "https://www.zotero.org/mhb3bh", "type": "text/html" } } }, "creatorSummary": "Vériter et al.", "parsedDate": "2011-09", "numChildren": 2 }, "data": { "key": "ANPP9PQI", "version": 144, "itemType": "journalArticle", "title": "The impact of hyperglycemia and the presence of encapsulated islets on oxygenation within a bioartificial pancreas in the presence of mesenchymal stem cells in a diabetic Wistar rat model", "creators": [ { "creatorType": "author", "firstName": "Sophie", "lastName": "Vériter" }, { "creatorType": "author", "firstName": "Najima", "lastName": "Aouassar" }, { "creatorType": "author", "firstName": "Pierre-Yves", "lastName": "Adnet" }, { "creatorType": "author", "firstName": "Marie-Sophie", "lastName": "Paridaens" }, { "creatorType": "author", "firstName": "Charlotte", "lastName": "Stuckman" }, { "creatorType": "author", "firstName": "Bénédicte", "lastName": "Jordan" }, { "creatorType": "author", "firstName": "Oussama", "lastName": "Karroum" }, { "creatorType": "author", "firstName": "Bernard", "lastName": "Gallez" }, { "creatorType": "author", "firstName": "Pierre", "lastName": "Gianello" }, { "creatorType": "author", "firstName": "Denis", "lastName": "Dufrane" } ], "abstractNote": "This study investigates the potential of bone marrow (BM-MSCs) versus adipose mesenchymal stem cells (AMSCs) to potentiate the oxygenation of encapsulated islets in a subcutaneous bioartificial pancreas. Oxygen pressures (inside subcutaneous implants) were followed in vivo (by electronic paramagnetic resonance) in non-diabetic/diabetic rats transplanted with encapsulated porcine islets or empty implants up to 4 weeks post-transplantation. After graft explantation, neoangiogenesis surrounding the implants was assessed by histomorphometry. Angiogenic properties of BM-MSCs and AMSCs were first assessed in vitro by incubation of the cells in hypoxia chambers, under normoxic/hypoxic and hypo-/hyperglycemic conditions, followed by quantification of vascular endothelial growth factor (VEGF) release. Second, the in vivo aspect was studied by subcutaneous transplantation of encapsulated BM-MSCs and AMSCs in diabetic rats and assessment of the cells’ angiogenic properties as described above. Diabetic state and islet encapsulation induced a significant decrease of oxygenation of the subcutaneous implant and an increased number of cells expressing VEGF. AMSCs demonstrated a significantly higher VEGF secretion than BM-MSCs in vitro. In vivo, AMSCs improved the implant’s oxygenation and vascularization. Diabetes and islet encapsulation significantly reduced the oxygenation of a subcutaneous bioartificial pancreas. AMSCs can improve oxygenation by VEGF release in hypoxia and hyperglycemia states.", "publicationTitle": "Biomaterials", "publisher": "", "place": "", "date": "September 2011", "volume": "32", "issue": "26", "section": "", "partNumber": "", "partTitle": "", "pages": "5945-5956", "series": "", "seriesTitle": "", "seriesText": "", "journalAbbreviation": "Biomaterials", "DOI": "10.1016/j.biomaterials.2011.02.061", "citationKey": "", "url": "http://www.sciencedirect.com/science/article/pii/S0142961211002389", "accessDate": "2013-04-29T22:54:18Z", "PMID": "", "PMCID": "", "ISSN": "0142-9612", "archive": "", "archiveLocation": "", "shortTitle": "", "language": "", "libraryCatalog": "ScienceDirect", "callNumber": "", "rights": "", "extra": "", "tags": [ { "tag": "Adipose tissue engineering", "type": 1 }, { "tag": "Diabetes", "type": 1 }, { "tag": "Islet", "type": 1 }, { "tag": "Oxygenation", "type": 1 }, { "tag": "Transplantation", "type": 1 }, { "tag": "stem cells", "type": 1 } ], "collections": [ "6M5WEIHQ" ], "relations": {}, "dateAdded": "2013-04-29T22:59:10Z", "dateModified": "2013-04-29T22:59:10Z" } }, { "key": "T3H83SR4", "version": 145, "library": { "type": "group", "id": 144458, "name": "IDEAS Sprng", "links": { "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng", "type": "text/html" } } }, "links": { "self": { "href": "https://api.zotero.org/groups/144458/items/T3H83SR4", "type": "application/json" }, "alternate": { "href": "https://www.zotero.org/groups/ideas_sprng/items/T3H83SR4", "type": "text/html" }, "up": { "href": "https://api.zotero.org/groups/144458/items/V8KSZ2JD", "type": "application/json" } }, "meta": { "createdByUser": { "id": 903888, "username": "mhb3bh", "name": "Mia", "links": { "alternate": { "href": "https://www.zotero.org/mhb3bh", "type": "text/html" } } } }, "data": { "key": "T3H83SR4", "version": 145, "parentItem": "V8KSZ2JD", "itemType": "attachment", "linkMode": "imported_url", "title": "ScienceDirect Snapshot", "accessDate": "2013-04-29T22:29:50Z", "url": "http://www.sciencedirect.com/science/article/pii/S0169409X04001462", "note": "", "contentType": "text/html", "charset": "utf-8", "filename": "S0169409X04001462.html", "md5": "eacda9d69f16abe05c21eafeea23c813", "mtime": 1367274592188, "tags": [], "relations": {}, "dateAdded": "2013-04-29T22:58:59Z", "dateModified": "2013-04-29T22:58:59Z" } } ]